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Items: 1 to 50 of 248

1.

Achieving enhanced bone regeneration using monetite granules with bone anabolic drug conjugates (C3 and C6) in rat mandibular defects.

Sheikh Z, Abdallah MN, Al-Jaf F, Chen G, Hamdan N, Young RN, Grynpas MD, Glogauer M.

J Biomed Mater Res B Appl Biomater. 2020 Mar 11. doi: 10.1002/jbm.b.34598. [Epub ahead of print]

PMID:
32159274
2.

Improved bone regeneration using bone anabolic drug conjugates (C3 and C6) with deproteinized bovine bone mineral as a carrier in rat mandibular defects.

Sheikh Z, Abdallah MN, Al-Jaf F, Chen G, Hamdan N, Young RN, Grynpas MD, Glogauer M.

J Periodontol. 2020 Feb 25. doi: 10.1002/JPER.19-0645. [Epub ahead of print]

PMID:
32100284
3.

In Vivo Bone Effects of a Novel Bisphosphonate-EP4a Conjugate Drug (C3) for Reversing Osteoporotic Bone Loss in an Ovariectomized Rat Model.

Sheikh Z, Chen G, Al-Jaf F, Thévenin M, Banks K, Glogauer M, Young RN, Grynpas MD.

JBMR Plus. 2019 Nov 9;3(12):e10237. doi: 10.1002/jbm4.10237. eCollection 2019 Dec.

4.

Ontogenetic changes to bone microstructure in an archaeologically derived sample of human ribs.

Beresheim AC, Pfeiffer S, Grynpas M.

J Anat. 2020 Mar;236(3):448-462. doi: 10.1111/joa.13116. Epub 2019 Nov 15.

PMID:
31729033
5.

Growth Hormone Increases Bone Toughness and Decreases Muscle Inflammation in Glucocorticoid-Treated Mdx Mice, Model of Duchenne Muscular Dystrophy.

Yoon SH, Grynpas MD, Mitchell J.

J Bone Miner Res. 2019 Aug;34(8):1473-1486. doi: 10.1002/jbmr.3718. Epub 2019 Jun 12.

PMID:
31188496
6.

Chlorthalidone Is Superior to Potassium Citrate in Reducing Calcium Phosphate Stones and Increasing Bone Quality in Hypercalciuric Stone-Forming Rats.

Krieger NS, Asplin JR, Granja I, Ramos FM, Flotteron C, Chen L, Wu TT, Grynpas MD, Bushinsky DA.

J Am Soc Nephrol. 2019 Jul;30(7):1163-1173. doi: 10.1681/ASN.2018101066. Epub 2019 May 17.

PMID:
31101664
7.

Ribose pre-treatment can protect the fatigue life of γ-irradiation sterilized bone.

Attia T, Grynpas M, Willett T.

Cell Tissue Bank. 2019 Jun;20(2):287-295. doi: 10.1007/s10561-019-09767-6. Epub 2019 Apr 24.

PMID:
31020508
8.

Differential response of human blood leukocytes to brushite, monetite, and calcium polyphosphate biomaterials.

Fine N, Sheikh Z, Al-Jaf F, Oveisi M, Borenstein A, Hu Y, Pilliar R, Grynpas M, Glogauer M.

J Biomed Mater Res B Appl Biomater. 2020 Jan;108(1):253-262. doi: 10.1002/jbm.b.34385. Epub 2019 Apr 22.

PMID:
31009177
9.

Increased Rates of Vitamin D Insufficiency in Boys With Duchenne Muscular Dystrophy Despite Higher Vitamin D3 Supplementation.

Bian Q, McAdam L, Grynpas M, Mitchell J, Harrington J.

Glob Pediatr Health. 2019 Mar 15;6:2333794X19835661. doi: 10.1177/2333794X19835661. eCollection 2019.

10.

Pre-clinical evaluation of bone allograft toughened with a novel sterilization method: An in vivo rabbit study.

Park SS, Zhang L, Attia T, Salat P, Banks K, Willett T, Grynpas M.

J Orthop Res. 2019 Apr;37(4):832-844. doi: 10.1002/jor.24269. Epub 2019 Mar 21.

11.

Low Sodium Diet Decreases Stone Formation in Genetic Hypercalciuric Stone-Forming Rats.

Krieger NS, Grynpas M, VandenEynde A, Asplin JR, Frick KK, Kim MH, Ramos FM, Granja I, Bushinsky DA.

Nephron. 2019;142(2):147-158. doi: 10.1159/000497117. Epub 2019 Feb 6.

12.

Intermittent PTH treatment improves bone and muscle in glucocorticoid treated Mdx mice: A model of Duchenne Muscular Dystrophy.

Yoon SH, Grynpas M, Mitchell J.

Bone. 2019 Apr;121:232-242. doi: 10.1016/j.bone.2019.01.028. Epub 2019 Feb 1.

PMID:
30716510
13.

A Novel Anabolic Conjugate (C3) in the Matrix of Dicalcium Phosphate Onlay Block Grafts for Achieving Vertical Bone Augmentation: An Experimental Study on Rabbit Calvaria.

Sheikh Z, Chen G, Thévenin M, Young RN, Grynpas MD, Glogauer M.

Int J Oral Maxillofac Implants. 2019 July/August;34(4):e51–e63. doi: 10.11607/jomi.7236. Epub 2019 Feb 4.

PMID:
30716148
14.

Processing and properties of Na-doped porous calcium polyphosphates - Mechanical properties and in vitro degradation characteristics.

Pilliar RM, Hu X, Grynpas MD, Kandel RA.

J Mech Behav Biomed Mater. 2019 Mar;91:355-365. doi: 10.1016/j.jmbbm.2018.12.025. Epub 2018 Dec 21.

PMID:
30658249
15.

Use of backscattered scanning electron microscopy to quantify the bone tissues of midthoracic human ribs.

Bereshiem AC, Pfeiffer SK, Grynpas MD, Alblas A.

Am J Phys Anthropol. 2019 Feb;168(2):262-278. doi: 10.1002/ajpa.23716.

PMID:
30628074
16.

Macrophage cells secrete factors including LRP1 that orchestrate the rejuvenation of bone repair in mice.

Vi L, Baht GS, Soderblom EJ, Whetstone H, Wei Q, Furman B, Puviindran V, Nadesan P, Foster M, Poon R, White JP, Yahara Y, Ng A, Barrientos T, Grynpas M, Mosely MA, Alman BA.

Nat Commun. 2018 Dec 5;9(1):5191. doi: 10.1038/s41467-018-07666-0.

17.

Pre-treatment with Pamidronate Improves Bone Mechanical Properties in Mdx Mice Treated with Glucocorticoids.

Chen J, Yoon SH, Grynpas MD, Mitchell J.

Calcif Tissue Int. 2019 Feb;104(2):182-192. doi: 10.1007/s00223-018-0482-5. Epub 2018 Oct 9.

PMID:
30302533
18.

Effect of 25-HydroxyVitamin D Deficiency and Its Interaction with Prednisone Treatment on Musculoskeletal Health in Growing Mdx Mice.

Yoon SH, Sugamori KS, Grynpas MD, Mitchell J.

Calcif Tissue Int. 2018 Sep;103(3):311-323. doi: 10.1007/s00223-018-0423-3. Epub 2018 Apr 24.

PMID:
29691609
19.

Targeting therapeutics to bone by conjugation with bisphosphonates.

Young RN, Grynpas MD.

Curr Opin Pharmacol. 2018 Jun;40:87-94. doi: 10.1016/j.coph.2018.03.010. Epub 2018 Apr 4. Review.

PMID:
29626715
20.

Sex-specific patterns in cortical and trabecular bone microstructure in the Kirsten Skeletal Collection, South Africa.

Beresheim AC, Pfeiffer SK, Grynpas MD, Alblas A.

Am J Hum Biol. 2018 May;30(3):e23108. doi: 10.1002/ajhb.23108. Epub 2018 Feb 7.

PMID:
29411454
21.

The effect of ribose pre-treatment of cortical bone on γ-irradiation sterilization effectiveness.

Attia T, Tupy J, Asker D, Hatton B, Grynpas M, Willett T.

Cell Tissue Bank. 2017 Dec;18(4):555-560. doi: 10.1007/s10561-017-9662-1. Epub 2017 Oct 14.

PMID:
29032461
22.

Overexpression of GαS in Murine Osteoblasts In Vivo Leads to Increased Bone Mass and Decreased Bone Quality.

Zhang L, Sugamori KS, Claridge C, Dela Cruz A, Grynpas MD, Mitchell J.

J Bone Miner Res. 2017 Nov;32(11):2171-2181. doi: 10.1002/jbmr.3223. Epub 2017 Aug 10.

23.

The CRH-Transgenic Cushingoid Mouse Is a Model of Glucocorticoid-Induced Osteoporosis.

Williams-Dautovich J, Yogendirarajah K, Dela Cruz A, Patel R, Tsai R, Morgan SA, Mitchell J, Grynpas MD, Cummins CL.

JBMR Plus. 2017 Jun 28;1(1):46-57. doi: 10.1002/jbm4.10009. eCollection 2017 Aug.

24.

Natural graft tissues and synthetic biomaterials for periodontal and alveolar bone reconstructive applications: a review.

Sheikh Z, Hamdan N, Ikeda Y, Grynpas M, Ganss B, Glogauer M.

Biomater Res. 2017 Jun 5;21:9. doi: 10.1186/s40824-017-0095-5. eCollection 2017. Review.

25.

Ubiquitin ligase RNF146 coordinates bone dynamics and energy metabolism.

Matsumoto Y, La Rose J, Lim M, Adissu HA, Law N, Mao X, Cong F, Mera P, Karsenty G, Goltzman D, Changoor A, Zhang L, Stajkowski M, Grynpas MD, Bergmann C, Rottapel R.

J Clin Invest. 2017 Jun 30;127(7):2612-2625. doi: 10.1172/JCI92233. Epub 2017 Jun 5.

26.

Development of a novel method for the strengthening and toughening of irradiation-sterilized bone allografts.

Attia T, Woodside M, Minhas G, Lu XZ, Josey DS, Burrow T, Grynpas M, Willett TL.

Cell Tissue Bank. 2017 Sep;18(3):323-334. doi: 10.1007/s10561-017-9634-5. Epub 2017 May 30.

PMID:
28560495
27.

RANKL coordinates multiple osteoclastogenic pathways by regulating expression of ubiquitin ligase RNF146.

Matsumoto Y, Larose J, Kent OA, Lim M, Changoor A, Zhang L, Storozhuk Y, Mao X, Grynpas MD, Cong F, Rottapel R.

J Clin Invest. 2017 Apr 3;127(4):1303-1315. doi: 10.1172/JCI90527. Epub 2017 Mar 13.

28.

The Lyme Disease Pathogen Borrelia burgdorferi Infects Murine Bone and Induces Trabecular Bone Loss.

Tang TT, Zhang L, Bansal A, Grynpas M, Moriarty TJ.

Infect Immun. 2017 Jan 26;85(2). pii: e00781-16. doi: 10.1128/IAI.00781-16. Print 2017 Feb.

29.

Bone histomorphometric changes in children with rheumatic disorders on chronic glucocorticoids.

Harrington J, Holmyard D, Silverman E, Sochett E, Grynpas M.

Pediatr Rheumatol Online J. 2016 Nov 10;14(1):58.

30.

Reciprocal stabilization of ABL and TAZ regulates osteoblastogenesis through transcription factor RUNX2.

Matsumoto Y, La Rose J, Kent OA, Wagner MJ, Narimatsu M, Levy AD, Omar MH, Tong J, Krieger JR, Riggs E, Storozhuk Y, Pasquale J, Ventura M, Yeganeh B, Post M, Moran MF, Grynpas MD, Wrana JL, Superti-Furga G, Koleske AJ, Pendergast AM, Rottapel R.

J Clin Invest. 2016 Dec 1;126(12):4482-4496. doi: 10.1172/JCI87802. Epub 2016 Oct 31.

31.

The incorporation of fluoride and strontium in hydroxyapatite affects the composition, structure, and mechanical properties of human cortical bone.

Riedel C, Zimmermann EA, Zustin J, Niecke M, Amling M, Grynpas M, Busse B.

J Biomed Mater Res A. 2017 Feb;105(2):433-442. doi: 10.1002/jbm.a.35917. Epub 2016 Oct 21.

PMID:
27684387
32.

Heterogeneity of osteoclast activity and bone turnover in different skeletal sites.

Goldberg S, Grynpas MD, Glogauer M.

Arch Oral Biol. 2016 Nov;71:134-143. doi: 10.1016/j.archoralbio.2016.06.026. Epub 2016 Jul 26.

PMID:
27505033
33.

Prophylactic pamidronate partially protects from glucocorticoid-induced bone loss in the mdx mouse model of Duchenne muscular dystrophy.

Yoon SH, Chen J, Grynpas MD, Mitchell J.

Bone. 2016 Sep;90:168-80. doi: 10.1016/j.bone.2016.06.015. Epub 2016 Jun 29.

PMID:
27373502
34.

Overexpression of Gα11 in Osteoblast Lineage Cells Suppresses the Osteoanabolic Response to Intermittent PTH and Exercise.

Dela Cruz A, Grynpas MD, Mitchell J.

Calcif Tissue Int. 2016 Oct;99(4):423-34. doi: 10.1007/s00223-016-0158-y. Epub 2016 Jun 14.

PMID:
27300035
35.

Phase transformations during processing and in vitro degradation of porous calcium polyphosphates.

Hu Y, Pilliar R, Grynpas M, Kandel R, Werner-Zwanziger U, Filiaggi M.

J Mater Sci Mater Med. 2016 Jul;27(7):117. doi: 10.1007/s10856-016-5725-2. Epub 2016 Jun 2.

PMID:
27255688
36.

Elevated Gα11 expression in osteoblast lineage cells promotes osteoclastogenesis and leads to enhanced trabecular bone accrual in response to pamidronate.

Dela Cruz A, Grynpas MD, Mitchell J.

Am J Physiol Endocrinol Metab. 2016 May 15;310(10):E811-20. doi: 10.1152/ajpendo.00049.2016. Epub 2016 Mar 22.

37.

Systemic Mesenchymal Stromal Cell Transplantation Prevents Functional Bone Loss in a Mouse Model of Age-Related Osteoporosis.

Kiernan J, Hu S, Grynpas MD, Davies JE, Stanford WL.

Stem Cells Transl Med. 2016 May;5(5):683-93. doi: 10.5966/sctm.2015-0231. Epub 2016 Mar 17.

38.

Calcium polyphosphate particulates for bone void filler applications.

Pilliar RM, Kandel RA, Grynpas MD, Theodoropoulos J, Hu Y, Allo B, Changoor A.

J Biomed Mater Res B Appl Biomater. 2017 May;105(4):874-884. doi: 10.1002/jbm.b.33623. Epub 2016 Feb 1.

PMID:
26833448
39.

Positive effects of bisphosphonates on bone and muscle in a mouse model of Duchenne muscular dystrophy.

Yoon SH, Sugamori KS, Grynpas MD, Mitchell J.

Neuromuscul Disord. 2016 Jan;26(1):73-84. doi: 10.1016/j.nmd.2015.09.015. Epub 2015 Oct 1.

PMID:
26494410
40.

Adynamic Bone Decreases Bone Toughness During Aging by Affecting Mineral and Matrix.

Ng AH, Omelon S, Variola F, Allo B, Willett TL, Alman BA, Grynpas MD.

J Bone Miner Res. 2016 Feb;31(2):369-79. doi: 10.1002/jbmr.2702. Epub 2015 Oct 6.

41.

In vivo effects of two novel ALN-EP4a conjugate drugs on bone in the ovariectomized rat model for reversing postmenopausal bone loss.

Hu S, Liu CC, Chen G, Willett T, Young RN, Grynpas MD.

Osteoporos Int. 2016 Feb;27(2):797-808. doi: 10.1007/s00198-015-3284-x. Epub 2015 Aug 14.

PMID:
26272313
42.

Bone Marrow Stress Decreases Osteogenic Progenitors.

Ng AH, Baht GS, Alman BA, Grynpas MD.

Calcif Tissue Int. 2015 Nov;97(5):476-86. doi: 10.1007/s00223-015-0032-3. Epub 2015 Jul 29.

PMID:
26220824
43.

Deletion of filamin A in monocytes protects cortical and trabecular bone from post-menopausal changes in bone microarchitecture.

Goldberg S, Glogauer J, Grynpas MD, Glogauer M.

Calcif Tissue Int. 2015 Aug;97(2):113-24. doi: 10.1007/s00223-015-9994-4. Epub 2015 Apr 17.

PMID:
25894069
44.

Effect of Potassium Citrate on Calcium Phosphate Stones in a Model of Hypercalciuria.

Krieger NS, Asplin JR, Frick KK, Granja I, Culbertson CD, Ng A, Grynpas MD, Bushinsky DA.

J Am Soc Nephrol. 2015 Dec;26(12):3001-8. doi: 10.1681/ASN.2014121223. Epub 2015 Apr 8.

45.

Long-term effects of castration on the skeleton of male rhesus monkeys (Macaca mulatta).

Kessler MJ, Wang Q, Cerroni AM, Grynpas MD, Gonzalez Velez OD, Rawlins RG, Ethun KF, Wimsatt JH, Kensler TB, Pritzker KP.

Am J Primatol. 2016 Jan;78(1):152-66. doi: 10.1002/ajp.22399. Epub 2015 Mar 16.

46.

Macrophages promote osteoblastic differentiation in-vivo: implications in fracture repair and bone homeostasis.

Vi L, Baht GS, Whetstone H, Ng A, Wei Q, Poon R, Mylvaganam S, Grynpas M, Alman BA.

J Bone Miner Res. 2015 Jun;30(6):1090-102. doi: 10.1002/jbmr.2422.

47.

Treatment with eldecalcitol positively affects mineralization, microdamage, and collagen crosslinks in primate bone.

Saito M, Grynpas MD, Burr DB, Allen MR, Smith SY, Doyle N, Amizuka N, Hasegawa T, Kida Y, Marumo K, Saito H.

Bone. 2015 Apr;73:8-15. doi: 10.1016/j.bone.2014.11.025. Epub 2014 Dec 5.

48.

Novel EP4 receptor agonist-bisphosphonate conjugate drug (C1) promotes bone formation and improves vertebral mechanical properties in the ovariectomized rat model of postmenopausal bone loss.

Liu CC, Hu S, Chen G, Georgiou J, Arns S, Kumar NS, Young RN, Grynpas MD.

J Bone Miner Res. 2015 Apr;30(4):670-80. doi: 10.1002/jbmr.2382.

49.

Development, validation and characterization of a novel mouse model of Adynamic Bone Disease (ABD).

Ng AH, Willett TL, Alman BA, Grynpas MD.

Bone. 2014 Nov;68:57-66. doi: 10.1016/j.bone.2014.07.037. Epub 2014 Aug 8.

PMID:
25111968
50.

Can OP-1 stimulate union in a rat model of pathological fracture post treatment for soft tissue sarcoma?

Nicholls F, Ng AH, Hu S, Janic K, Fallis C, Willett T, Grynpas M, Ferguson P.

J Orthop Res. 2014 Oct;32(10):1252-63. doi: 10.1002/jor.22661. Epub 2014 Jun 25.

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