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Items: 1 to 50 of 274

1.

Pro-inflammatory histidyl-tRNA synthetase-specific CD4+ T cells in the blood and lung of patients with idiopathic inflammatory myopathies.

Galindo-Feria AS, Albrecht I, Fernandes-Cerqueira C, Notarnicola A, James EA, Herrath J, Dastmalchi M, Sandalova T, Rönnblom L, Jakobsson PJ, Fathi M, Achour A, Grunewald J, Malmström V, Lundberg IE.

Arthritis Rheumatol. 2019 Aug 12. doi: 10.1002/art.41075. [Epub ahead of print]

PMID:
31403245
2.

Publisher Correction: Sarcoidosis.

Grunewald J, Grutters JC, Arkema EV, Saketkoo LA, Moller DR, Müller-Quernheim J.

Nat Rev Dis Primers. 2019 Jul 16;5(1):49. doi: 10.1038/s41572-019-0107-y.

PMID:
31311930
3.

Tobacco smoking induces changes in true DNA methylation, hydroxymethylation and gene expression in bronchoalveolar lavage cells.

Ringh MV, Hagemann-Jensen M, Needhamsen M, Kular L, Breeze CE, Sjöholm LK, Slavec L, Kullberg S, Wahlström J, Grunewald J, Brynedal B, Liu Y, Almgren M, Jagodic M, Öckinger J, Ekström TJ.

EBioMedicine. 2019 Jul 11. pii: S2352-3964(19)30441-4. doi: 10.1016/j.ebiom.2019.07.006. [Epub ahead of print]

4.

Sarcoidosis.

Grunewald J, Grutters JC, Arkema EV, Saketkoo LA, Moller DR, Müller-Quernheim J.

Nat Rev Dis Primers. 2019 Jul 4;5(1):45. doi: 10.1038/s41572-019-0096-x. Review. Erratum in: Nat Rev Dis Primers. 2019 Jul 16;5(1):49.

PMID:
31273209
5.

Site-Specific Antibody Labeling Using Phosphopantetheinyl Transferase-Catalyzed Ligation.

Grünewald J, Brock A, Geierstanger BH.

Methods Mol Biol. 2019;2012:237-278. doi: 10.1007/978-1-4939-9546-2_13.

PMID:
31161512
6.

Correspondence for "Clinical epidemiology of familial sarcoidosis: A systematic literature review".

Rossides M, Grunewald J, Eklund A, Kullberg S, Askling J, Arkema EV.

Respir Med. 2019 May 13. pii: S0954-6111(19)30155-6. doi: 10.1016/j.rmed.2019.05.003. [Epub ahead of print] No abstract available.

PMID:
31104964
7.

SpotLight Proteomics-A IgG-Enrichment Phenotype Profiling Approach with Clinical Implications.

Lundström SL, Heyder T, Wiklundh E, Zhang B, Eklund A, Grunewald J, Zubarev RA.

Int J Mol Sci. 2019 May 1;20(9). pii: E2157. doi: 10.3390/ijms20092157.

8.

Moving target: shifting the focus to pulmonary sarcoidosis as an autoimmune spectrum disorder.

Kaiser Y, Eklund A, Grunewald J.

Eur Respir J. 2019 Jul 11;54(1). pii: 1802153. doi: 10.1183/13993003.021532018. Print 2019 Jul. Review.

PMID:
31000677
9.

Transcriptome-wide off-target RNA editing induced by CRISPR-guided DNA base editors.

Grünewald J, Zhou R, Garcia SP, Iyer S, Lareau CA, Aryee MJ, Joung JK.

Nature. 2019 May;569(7756):433-437. doi: 10.1038/s41586-019-1161-z. Epub 2019 Apr 17.

PMID:
30995674
10.

Mapping mononuclear phagocytes in blood, lungs, and lymph nodes of sarcoidosis patients.

Lepzien R, Rankin G, Pourazar J, Muala A, Eklund A, Grunewald J, Blomberg A, Smed-Sörensen A.

J Leukoc Biol. 2019 Apr;105(4):797-807. doi: 10.1002/JLB.5A0718-280RR. Epub 2019 Feb 11.

PMID:
30742337
11.

Soluble epoxide hydrolase derived lipid mediators are elevated in bronchoalveolar lavage fluid from patients with sarcoidosis: a cross-sectional study.

Sjödin MOD, Checa A, Yang M, Dahlén SE, Wheelock ÅM, Eklund A, Grunewald J, Wheelock CE.

Respir Res. 2018 Dec 3;19(1):236. doi: 10.1186/s12931-018-0939-0.

12.

Work ability before and after sarcoidosis diagnosis in Sweden.

Arkema EV, Eklund A, Grunewald J, Bruze G.

Respir Med. 2018 Nov;144S:S7-S12. doi: 10.1016/j.rmed.2018.09.016. Epub 2018 Oct 5.

PMID:
30343984
13.

GFR estimation in lenalidomide treatment of multiple myeloma patients: a prospective cohort study.

Schmidts A, Grünewald J, Kleber M, Terpos E, Ihorst G, Reinhardt H, Walz G, Wäsch R, Engelhardt M, Zschiedrich S.

Clin Exp Nephrol. 2019 Feb;23(2):199-206. doi: 10.1007/s10157-018-1626-7. Epub 2018 Aug 20.

PMID:
30128942
14.

Altered Fc galactosylation in IgG4 is a potential serum marker for chronic lung disease.

Heyder T, Wiklundh E, Eklund A, James A, Grunewald J, Zubarev RA, Lundström SL.

ERJ Open Res. 2018 Jul 31;4(3). pii: 00033-2018. doi: 10.1183/23120541.00033-2018. eCollection 2018 Jul.

15.

In Situ Humoral Immunity to Vimentin in HLA-DRB1*03+ Patients With Pulmonary Sarcoidosis.

Kinloch AJ, Kaiser Y, Wolfgeher D, Ai J, Eklund A, Clark MR, Grunewald J.

Front Immunol. 2018 Jul 9;9:1516. doi: 10.3389/fimmu.2018.01516. eCollection 2018.

16.

Familial aggregation and heritability of sarcoidosis: a Swedish nested case-control study.

Rossides M, Grunewald J, Eklund A, Kullberg S, Di Giuseppe D, Askling J, Arkema EV.

Eur Respir J. 2018 Aug 16;52(2). pii: 1800385. doi: 10.1183/13993003.00385-2018. Print 2018 Aug.

PMID:
29946010
17.

Expression of MATE1, P-gp, OCTN1 and OCTN2, in epithelial and immune cells in the lung of COPD and healthy individuals.

Berg T, Hegelund-Myrbäck T, Öckinger J, Zhou XH, Brännström M, Hagemann-Jensen M, Werkström V, Seidegård J, Grunewald J, Nord M, Gustavsson L.

Respir Res. 2018 Apr 20;19(1):68. doi: 10.1186/s12931-018-0760-9.

18.

The rheumatic disease-associated FAM167A-BLK locus encodes DIORA-1, a novel disordered protein expressed highly in bronchial epithelium and alveolar macrophages.

Mentlein L, Thorlacius GE, Meneghel L, Aqrawi LA, Ramírez Sepúlveda JI, Grunewald J, Espinosa A, Wahren-Herlenius M.

Clin Exp Immunol. 2018 Aug;193(2):167-177. doi: 10.1111/cei.13138. Epub 2018 May 16.

19.

Proteomic profiling of lung immune cells reveals dysregulation of phagocytotic pathways in female-dominated molecular COPD phenotype.

Yang M, Kohler M, Heyder T, Forsslund H, Garberg HK, Karimi R, Grunewald J, Berven FS, Nyrén S, Magnus Sköld C, Wheelock ÅM.

Respir Res. 2018 Mar 8;19(1):39. doi: 10.1186/s12931-017-0699-2.

20.

Long-term smoking alters abundance of over half of the proteome in bronchoalveolar lavage cell in smokers with normal spirometry, with effects on molecular pathways associated with COPD.

Yang M, Kohler M, Heyder T, Forsslund H, Garberg HK, Karimi R, Grunewald J, Berven FS, Magnus Sköld C, Wheelock ÅM.

Respir Res. 2018 Mar 8;19(1):40. doi: 10.1186/s12931-017-0695-6.

21.

Sarcoidosis mortality in Sweden: a population-based cohort study.

Rossides M, Kullberg S, Askling J, Eklund A, Grunewald J, Arkema EV.

Eur Respir J. 2018 Feb 21;51(2). pii: 1701815. doi: 10.1183/13993003.01815-2017. Print 2018 Feb.

22.

Th17-lineage cells in pulmonary sarcoidosis and Löfgren's syndrome: Friend or foe?

Miedema JR, Kaiser Y, Broos CE, Wijsenbeek MS, Grunewald J, Kool M.

J Autoimmun. 2018 Feb;87:82-96. doi: 10.1016/j.jaut.2017.12.012. Epub 2018 Jan 5. Review.

PMID:
29310925
23.

Enhanced CD8+ cytolytic T cell responses in the peripheral circulation of patients with sarcoidosis and non-Löfgren's disease.

Parasa VR, Forsslund H, Enger T, Lorenz D, Kullberg S, Eklund A, Sköld M, Wahlström J, Grunewald J, Brighenti S.

Respir Med. 2018 May;138S:S38-S44. doi: 10.1016/j.rmed.2017.10.006. Epub 2017 Oct 13.

PMID:
29055517
24.

Evidence of fatigue, disordered sleep and peripheral inflammation, but not increased brain TSPO expression, in seasonal allergy: A [11C]PBR28 PET study.

Tamm S, Cervenka S, Forsberg A, Estelius J, Grunewald J, Gyllfors P, Karshikoff B, Kosek E, Lampa J, Lensmar C, Strand V, Åkerstedt T, Halldin C, Ingvar M, Olgart Höglund C, Lekander M.

Brain Behav Immun. 2018 Feb;68:146-157. doi: 10.1016/j.bbi.2017.10.013. Epub 2017 Oct 18.

25.

Mass Cytometry Identifies Distinct Lung CD4+ T Cell Patterns in Löfgren's Syndrome and Non-Löfgren's Syndrome Sarcoidosis.

Kaiser Y, Lakshmikanth T, Chen Y, Mikes J, Eklund A, Brodin P, Achour A, Grunewald J.

Front Immunol. 2017 Sep 12;8:1130. doi: 10.3389/fimmu.2017.01130. eCollection 2017.

26.

Shared αβ TCR Usage in Lungs of Sarcoidosis Patients with Löfgren's Syndrome.

Mitchell AM, Kaiser Y, Falta MT, Munson DJ, Landry LG, Eklund A, Nakayama M, Slansky JE, Grunewald J, Fontenot AP.

J Immunol. 2017 Oct 1;199(7):2279-2290. doi: 10.4049/jimmunol.1700570. Epub 2017 Aug 21.

27.

Löfgren's Syndrome: Diagnosis, Management, and Disease Pathogenesis.

Karakaya B, Kaiser Y, van Moorsel CHM, Grunewald J.

Semin Respir Crit Care Med. 2017 Aug;38(4):463-476. doi: 10.1055/s-0037-1602380. Epub 2017 Jul 27. Review. No abstract available.

PMID:
28750461
28.

Common variants of T-cells contribute differently to phenotypic variation in sarcoidosis.

Rivera NV, Hagemann-Jensen M, Ferreira MAR, Kullberg S, Eklund A, Martin NG, Padyukov L, Grunewald J.

Sci Rep. 2017 Jul 17;7(1):5623. doi: 10.1038/s41598-017-05754-7.

29.

Optimization of an Enzymatic Antibody-Drug Conjugation Approach Based on Coenzyme A Analogs.

Grünewald J, Jin Y, Vance J, Read J, Wang X, Wan Y, Zhou H, Ou W, Klock HE, Peters EC, Uno T, Brock A, Geierstanger BH.

Bioconjug Chem. 2017 Jul 19;28(7):1906-1915. doi: 10.1021/acs.bioconjchem.7b00236. Epub 2017 Jun 14.

PMID:
28590752
30.

Pulmonary Extracellular Vesicles as Mediators of Local and Systemic Inflammation.

Wahlund CJE, Eklund A, Grunewald J, Gabrielsson S.

Front Cell Dev Biol. 2017 Apr 26;5:39. doi: 10.3389/fcell.2017.00039. eCollection 2017. Review.

31.

SNP Variants in Major Histocompatibility Complex Are Associated with Sarcoidosis Susceptibility-A Joint Analysis in Four European Populations.

Wolin A, Lahtela EL, Anttila V, Petrek M, Grunewald J, van Moorsel CHM, Eklund A, Grutters JC, Kolek V, Mrazek F, Kishore A, Padyukov L, Pietinalho A, Ronninger M, Seppänen M, Selroos O, Lokki ML.

Front Immunol. 2017 Apr 19;8:422. doi: 10.3389/fimmu.2017.00422. eCollection 2017.

32.

Humoral immune profiling of mycobacterial antigen recognition in sarcoidosis and Löfgren's syndrome using high-content peptide microarrays.

Ferrara G, Valentini D, Rao M, Wahlström J, Grunewald J, Larsson LO, Brighenti S, Dodoo E, Zumla A, Maeurer M.

Int J Infect Dis. 2017 Mar;56:167-175. doi: 10.1016/j.ijid.2017.01.021. Epub 2017 Jan 31.

33.

Clinical career and research: are they mutually exclusive?

Gori T, Grünewald J.

Eur Heart J. 2017 Jan 7;38(2):72-74. doi: 10.1093/eurheartj/ehw608. No abstract available.

PMID:
28158634
34.

Gender differences in the T-cell profiles of the airways in COPD patients associated with clinical phenotypes.

Forsslund H, Yang M, Mikko M, Karimi R, Nyrén S, Engvall B, Grunewald J, Merikallio H, Kaarteenaho R, Wahlström J, Wheelock ÅM, Sköld CM.

Int J Chron Obstruct Pulmon Dis. 2016 Dec 20;12:35-48. doi: 10.2147/COPD.S113625. eCollection 2017.

35.

The lung microbiota in early rheumatoid arthritis and autoimmunity.

Scher JU, Joshua V, Artacho A, Abdollahi-Roodsaz S, Öckinger J, Kullberg S, Sköld M, Eklund A, Grunewald J, Clemente JC, Ubeda C, Segal LN, Catrina AI.

Microbiome. 2016 Nov 17;4(1):60.

36.

Immune cell activation and cytokine release after stimulation of whole blood with pneumococcal C-polysaccharide and capsular polysaccharides.

Sundberg-Kövamees M, Grunewald J, Wahlström J.

Int J Infect Dis. 2016 Nov;52:1-8. doi: 10.1016/j.ijid.2016.07.004. Epub 2016 Jul 18.

37.

Distinctive Regulatory T Cells and Altered Cytokine Profile Locally in the Airways of Young Smokers with Normal Lung Function.

Ostadkarampour M, Müller M, Öckinger J, Kullberg S, Lindén A, Eklund A, Grunewald J, Wahlström J.

PLoS One. 2016 Oct 31;11(10):e0164751. doi: 10.1371/journal.pone.0164751. eCollection 2016.

38.

Expression Profile of Six RNA-Binding Proteins in Pulmonary Sarcoidosis.

Navratilova Z, Novosadova E, Hagemann-Jensen M, Kullberg S, Kolek V, Grunewald J, Petrek M.

PLoS One. 2016 Aug 30;11(8):e0161669. doi: 10.1371/journal.pone.0161669. eCollection 2016.

39.

Pulmonary sarcoidosis is associated with exosomal vitamin D-binding protein and inflammatory molecules.

Martinez-Bravo MJ, Wahlund CJ, Qazi KR, Moulder R, Lukic A, Rådmark O, Lahesmaa R, Grunewald J, Eklund A, Gabrielsson S.

J Allergy Clin Immunol. 2017 Apr;139(4):1186-1194. doi: 10.1016/j.jaci.2016.05.051. Epub 2016 Aug 23.

PMID:
27566455
40.

Sarcoidosis incidence and prevalence: a nationwide register-based assessment in Sweden.

Arkema EV, Grunewald J, Kullberg S, Eklund A, Askling J.

Eur Respir J. 2016 Dec;48(6):1690-1699. doi: 10.1183/13993003.00477-2016. Epub 2016 Jul 28.

41.

Approach for Identifying Human Leukocyte Antigen (HLA)-DR Bound Peptides from Scarce Clinical Samples.

Heyder T, Kohler M, Tarasova NK, Haag S, Rutishauser D, Rivera NV, Sandin C, Mia S, Malmström V, Wheelock ÅM, Wahlström J, Holmdahl R, Eklund A, Zubarev RA, Grunewald J, Ytterberg AJ.

Mol Cell Proteomics. 2016 Sep;15(9):3017-29. doi: 10.1074/mcp.M116.060764. Epub 2016 Jul 24.

42.

T-cell activation and HLA-regulated response to smoking in the deep airways of patients with multiple sclerosis.

Öckinger J, Hagemann-Jensen M, Kullberg S, Engvall B, Eklund A, Grunewald J, Piehl F, Olsson T, Wahlström J.

Clin Immunol. 2016 Aug;169:114-120. doi: 10.1016/j.clim.2016.06.006. Epub 2016 Jun 23.

PMID:
27339331
43.

Elevated levels of FN1 and CCL2 in bronchoalveolar lavage fluid from sarcoidosis patients.

Hamsten C, Wiklundh E, Grönlund H, Schwenk JM, Uhlén M, Eklund A, Nilsson P, Grunewald J, Häggmark-Månberg A.

Respir Res. 2016 Jun 4;17(1):69. doi: 10.1186/s12931-016-0381-0.

44.

Expanded lung T-bet+RORγT+ CD4+ T-cells in sarcoidosis patients with a favourable disease phenotype.

Kaiser Y, Lepzien R, Kullberg S, Eklund A, Smed-Sörensen A, Grunewald J.

Eur Respir J. 2016 Aug;48(2):484-94. doi: 10.1183/13993003.00092-2016. Epub 2016 May 26.

45.

Protein profiles of CCL5, HPGDS, and NPSR1 in plasma reveal association with childhood asthma.

Hamsten C, Häggmark A, Grundström J, Mikus M, Lindskog C, Konradsen JR, Eklund A, Pershagen G, Wickman M, Grunewald J, Melén E, Hedlin G, Nilsson P, van Hage M.

Allergy. 2016 Sep;71(9):1357-61. doi: 10.1111/all.12927. Epub 2016 May 25.

PMID:
27145233
46.

Alterations in the membrane-associated proteome fraction of alveolar macrophages in sarcoidosis.

Kjellin H, Silva E, Branca RM, Eklund A, Jakobsson PJ, Grunewald J, Lehtiö J, Wheelock ÅM.

Sarcoidosis Vasc Diffuse Lung Dis. 2016 Mar 29;33(1):17-28.

PMID:
27055832
47.

High-Density Genetic Mapping Identifies New Susceptibility Variants in Sarcoidosis Phenotypes and Shows Genomic-driven Phenotypic Differences.

Rivera NV, Ronninger M, Shchetynsky K, Franke A, Nöthen MM, Müller-Quernheim J, Schreiber S, Adrianto I, Karakaya B, van Moorsel CH, Navratilova Z, Kolek V, Rybicki BA, Iannuzzi MC, Petrek M, Grutters JC, Montgomery C, Fischer A, Eklund A, Padyukov L, Grunewald J.

Am J Respir Crit Care Med. 2016 May 1;193(9):1008-22. doi: 10.1164/rccm.201507-1372OC.

48.

Efficient Preparation of Site-Specific Antibody-Drug Conjugates Using Phosphopantetheinyl Transferases.

Grünewald J, Klock HE, Cellitti SE, Bursulaya B, McMullan D, Jones DH, Chiu HP, Wang X, Patterson P, Zhou H, Vance J, Nigoghossian E, Tong H, Daniel D, Mallet W, Ou W, Uno T, Brock A, Lesley SA, Geierstanger BH.

Bioconjug Chem. 2015 Dec 16;26(12):2554-62. doi: 10.1021/acs.bioconjchem.5b00558. Epub 2015 Dec 4.

PMID:
26588668
49.

T-cell receptor-HLA-DRB1 associations suggest specific antigens in pulmonary sarcoidosis.

Grunewald J, Kaiser Y, Ostadkarampour M, Rivera NV, Vezzi F, Lötstedt B, Olsen RA, Sylwan L, Lundin S, Käller M, Sandalova T, Ahlgren KM, Wahlström J, Achour A, Ronninger M, Eklund A.

Eur Respir J. 2016 Mar;47(3):898-909. doi: 10.1183/13993003.01209-2015. Epub 2015 Nov 19.

50.

Signs of immune activation and local inflammation are present in the bronchial tissue of patients with untreated early rheumatoid arthritis.

Reynisdottir G, Olsen H, Joshua V, Engström M, Forsslund H, Karimi R, Sköld CM, Nyren S, Eklund A, Grunewald J, Catrina AI.

Ann Rheum Dis. 2016 Sep;75(9):1722-7. doi: 10.1136/annrheumdis-2015-208216. Epub 2015 Nov 3.

PMID:
26530319

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