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Items: 1 to 50 of 279

1.

Sarcoidosis diagnosis and treatment in Sweden: A register-based assessment of variations by region and calendar period.

Rossides M, Kullberg S, Eklund A, Grunewald J, Arkema EV.

Respir Med. 2020 Jan;161:105846. doi: 10.1016/j.rmed.2019.105846. Epub 2019 Nov 26.

PMID:
32056723
2.

Are infectious diseases risk factors for sarcoidosis or a result of reverse causation? Findings from a population-based nested case-control study.

Rossides M, Kullberg S, Askling J, Eklund A, Grunewald J, Di Giuseppe D, Arkema EV.

Eur J Epidemiol. 2020 Feb 11. doi: 10.1007/s10654-020-00611-w. [Epub ahead of print]

PMID:
32048110
3.

A Gene-Environment Interaction Between Smoking and Gene polymorphisms Provides a High Risk of Two Subgroups of Sarcoidosis.

Rivera NV, Patasova K, Kullberg S, Diaz-Gallo LM, Iseda T, Bengtsson C, Alfredsson L, Eklund A, Kockum I, Grunewald J, Padyukov L.

Sci Rep. 2019 Dec 9;9(1):18633. doi: 10.1038/s41598-019-54612-1.

4.

CRISPR DNA base editors with reduced RNA off-target and self-editing activities.

Grünewald J, Zhou R, Iyer S, Lareau CA, Garcia SP, Aryee MJ, Joung JK.

Nat Biotechnol. 2019 Sep;37(9):1041-1048. doi: 10.1038/s41587-019-0236-6. Epub 2019 Sep 2.

PMID:
31477922
5.

Subpopulations of cells from bronchoalveolar lavage can predict prognosis in sarcoidosis.

Darlington P, Kullberg S, Eklund A, Grunewald J.

Eur Respir J. 2020 Jan 30;55(1). pii: 1901450. doi: 10.1183/13993003.01450-2019. Print 2020 Jan. No abstract available.

6.

Proinflammatory Histidyl-Transfer RNA Synthetase-Specific CD4+ T Cells in the Blood and Lungs of Patients With Idiopathic Inflammatory Myopathies.

Galindo-Feria AS, Albrecht I, Fernandes-Cerqueira C, Notarnicola A, James EA, Herrath J, Dastmalchi M, Sandalova T, Rönnblom L, Jakobsson PJ, Fathi M, Achour A, Grunewald J, Malmström V, Lundberg IE.

Arthritis Rheumatol. 2020 Jan;72(1):179-191. doi: 10.1002/art.41075. Epub 2019 Nov 26.

PMID:
31403245
7.

Publisher Correction: Sarcoidosis.

Grunewald J, Grutters JC, Arkema EV, Saketkoo LA, Moller DR, Müller-Quernheim J.

Nat Rev Dis Primers. 2019 Jul 16;5(1):49. doi: 10.1038/s41572-019-0107-y.

PMID:
31311930
8.

Tobacco smoking induces changes in true DNA methylation, hydroxymethylation and gene expression in bronchoalveolar lavage cells.

Ringh MV, Hagemann-Jensen M, Needhamsen M, Kular L, Breeze CE, Sjöholm LK, Slavec L, Kullberg S, Wahlström J, Grunewald J, Brynedal B, Liu Y, Almgren M, Jagodic M, Öckinger J, Ekström TJ.

EBioMedicine. 2019 Aug;46:290-304. doi: 10.1016/j.ebiom.2019.07.006. Epub 2019 Jul 12.

9.

Sarcoidosis.

Grunewald J, Grutters JC, Arkema EV, Saketkoo LA, Moller DR, Müller-Quernheim J.

Nat Rev Dis Primers. 2019 Jul 4;5(1):45. doi: 10.1038/s41572-019-0096-x. Review. Erratum in: Nat Rev Dis Primers. 2019 Jul 16;5(1):49.

PMID:
31273209
10.

Site-Specific Antibody Labeling Using Phosphopantetheinyl Transferase-Catalyzed Ligation.

Grünewald J, Brock A, Geierstanger BH.

Methods Mol Biol. 2019;2012:237-278. doi: 10.1007/978-1-4939-9546-2_13.

PMID:
31161512
11.

Correspondence for "Clinical epidemiology of familial sarcoidosis: A systematic literature review".

Rossides M, Grunewald J, Eklund A, Kullberg S, Askling J, Arkema EV.

Respir Med. 2019 Nov - Dec;160:105696. doi: 10.1016/j.rmed.2019.05.003. Epub 2019 May 13. No abstract available.

PMID:
31104964
12.

SpotLight Proteomics-A IgG-Enrichment Phenotype Profiling Approach with Clinical Implications.

Lundström SL, Heyder T, Wiklundh E, Zhang B, Eklund A, Grunewald J, Zubarev RA.

Int J Mol Sci. 2019 May 1;20(9). pii: E2157. doi: 10.3390/ijms20092157.

13.

Moving target: shifting the focus to pulmonary sarcoidosis as an autoimmune spectrum disorder.

Kaiser Y, Eklund A, Grunewald J.

Eur Respir J. 2019 Jul 11;54(1). pii: 1802153. doi: 10.1183/13993003.021532018. Print 2019 Jul. Review.

PMID:
31000677
14.

Transcriptome-wide off-target RNA editing induced by CRISPR-guided DNA base editors.

Grünewald J, Zhou R, Garcia SP, Iyer S, Lareau CA, Aryee MJ, Joung JK.

Nature. 2019 May;569(7756):433-437. doi: 10.1038/s41586-019-1161-z. Epub 2019 Apr 17.

15.

Mapping mononuclear phagocytes in blood, lungs, and lymph nodes of sarcoidosis patients.

Lepzien R, Rankin G, Pourazar J, Muala A, Eklund A, Grunewald J, Blomberg A, Smed-Sörensen A.

J Leukoc Biol. 2019 Apr;105(4):797-807. doi: 10.1002/JLB.5A0718-280RR. Epub 2019 Feb 11.

16.

Soluble epoxide hydrolase derived lipid mediators are elevated in bronchoalveolar lavage fluid from patients with sarcoidosis: a cross-sectional study.

Sjödin MOD, Checa A, Yang M, Dahlén SE, Wheelock ÅM, Eklund A, Grunewald J, Wheelock CE.

Respir Res. 2018 Dec 3;19(1):236. doi: 10.1186/s12931-018-0939-0.

17.

Work ability before and after sarcoidosis diagnosis in Sweden.

Arkema EV, Eklund A, Grunewald J, Bruze G.

Respir Med. 2018 Nov;144S:S7-S12. doi: 10.1016/j.rmed.2018.09.016. Epub 2018 Oct 5.

PMID:
30343984
18.

GFR estimation in lenalidomide treatment of multiple myeloma patients: a prospective cohort study.

Schmidts A, Grünewald J, Kleber M, Terpos E, Ihorst G, Reinhardt H, Walz G, Wäsch R, Engelhardt M, Zschiedrich S.

Clin Exp Nephrol. 2019 Feb;23(2):199-206. doi: 10.1007/s10157-018-1626-7. Epub 2018 Aug 20.

PMID:
30128942
19.

Altered Fc galactosylation in IgG4 is a potential serum marker for chronic lung disease.

Heyder T, Wiklundh E, Eklund A, James A, Grunewald J, Zubarev RA, Lundström SL.

ERJ Open Res. 2018 Jul 31;4(3). pii: 00033-2018. doi: 10.1183/23120541.00033-2018. eCollection 2018 Jul.

20.

In Situ Humoral Immunity to Vimentin in HLA-DRB1*03+ Patients With Pulmonary Sarcoidosis.

Kinloch AJ, Kaiser Y, Wolfgeher D, Ai J, Eklund A, Clark MR, Grunewald J.

Front Immunol. 2018 Jul 9;9:1516. doi: 10.3389/fimmu.2018.01516. eCollection 2018.

21.

Familial aggregation and heritability of sarcoidosis: a Swedish nested case-control study.

Rossides M, Grunewald J, Eklund A, Kullberg S, Di Giuseppe D, Askling J, Arkema EV.

Eur Respir J. 2018 Aug 16;52(2). pii: 1800385. doi: 10.1183/13993003.00385-2018. Print 2018 Aug.

22.

Expression of MATE1, P-gp, OCTN1 and OCTN2, in epithelial and immune cells in the lung of COPD and healthy individuals.

Berg T, Hegelund-Myrbäck T, Öckinger J, Zhou XH, Brännström M, Hagemann-Jensen M, Werkström V, Seidegård J, Grunewald J, Nord M, Gustavsson L.

Respir Res. 2018 Apr 20;19(1):68. doi: 10.1186/s12931-018-0760-9.

23.

The rheumatic disease-associated FAM167A-BLK locus encodes DIORA-1, a novel disordered protein expressed highly in bronchial epithelium and alveolar macrophages.

Mentlein L, Thorlacius GE, Meneghel L, Aqrawi LA, Ramírez Sepúlveda JI, Grunewald J, Espinosa A, Wahren-Herlenius M.

Clin Exp Immunol. 2018 Aug;193(2):167-177. doi: 10.1111/cei.13138. Epub 2018 May 16.

24.

Proteomic profiling of lung immune cells reveals dysregulation of phagocytotic pathways in female-dominated molecular COPD phenotype.

Yang M, Kohler M, Heyder T, Forsslund H, Garberg HK, Karimi R, Grunewald J, Berven FS, Nyrén S, Magnus Sköld C, Wheelock ÅM.

Respir Res. 2018 Mar 8;19(1):39. doi: 10.1186/s12931-017-0699-2.

25.

Long-term smoking alters abundance of over half of the proteome in bronchoalveolar lavage cell in smokers with normal spirometry, with effects on molecular pathways associated with COPD.

Yang M, Kohler M, Heyder T, Forsslund H, Garberg HK, Karimi R, Grunewald J, Berven FS, Magnus Sköld C, Wheelock ÅM.

Respir Res. 2018 Mar 8;19(1):40. doi: 10.1186/s12931-017-0695-6.

26.

Sarcoidosis mortality in Sweden: a population-based cohort study.

Rossides M, Kullberg S, Askling J, Eklund A, Grunewald J, Arkema EV.

Eur Respir J. 2018 Feb 21;51(2). pii: 1701815. doi: 10.1183/13993003.01815-2017. Print 2018 Feb.

27.

Th17-lineage cells in pulmonary sarcoidosis and Löfgren's syndrome: Friend or foe?

Miedema JR, Kaiser Y, Broos CE, Wijsenbeek MS, Grunewald J, Kool M.

J Autoimmun. 2018 Feb;87:82-96. doi: 10.1016/j.jaut.2017.12.012. Epub 2018 Jan 5. Review.

PMID:
29310925
28.

Enhanced CD8+ cytolytic T cell responses in the peripheral circulation of patients with sarcoidosis and non-Löfgren's disease.

Parasa VR, Forsslund H, Enger T, Lorenz D, Kullberg S, Eklund A, Sköld M, Wahlström J, Grunewald J, Brighenti S.

Respir Med. 2018 May;138S:S38-S44. doi: 10.1016/j.rmed.2017.10.006. Epub 2017 Oct 13.

PMID:
29055517
29.

Evidence of fatigue, disordered sleep and peripheral inflammation, but not increased brain TSPO expression, in seasonal allergy: A [11C]PBR28 PET study.

Tamm S, Cervenka S, Forsberg A, Estelius J, Grunewald J, Gyllfors P, Karshikoff B, Kosek E, Lampa J, Lensmar C, Strand V, Åkerstedt T, Halldin C, Ingvar M, Olgart Höglund C, Lekander M.

Brain Behav Immun. 2018 Feb;68:146-157. doi: 10.1016/j.bbi.2017.10.013. Epub 2017 Oct 18.

30.

Mass Cytometry Identifies Distinct Lung CD4+ T Cell Patterns in Löfgren's Syndrome and Non-Löfgren's Syndrome Sarcoidosis.

Kaiser Y, Lakshmikanth T, Chen Y, Mikes J, Eklund A, Brodin P, Achour A, Grunewald J.

Front Immunol. 2017 Sep 12;8:1130. doi: 10.3389/fimmu.2017.01130. eCollection 2017.

31.

Shared αβ TCR Usage in Lungs of Sarcoidosis Patients with Löfgren's Syndrome.

Mitchell AM, Kaiser Y, Falta MT, Munson DJ, Landry LG, Eklund A, Nakayama M, Slansky JE, Grunewald J, Fontenot AP.

J Immunol. 2017 Oct 1;199(7):2279-2290. doi: 10.4049/jimmunol.1700570. Epub 2017 Aug 21.

32.

Löfgren's Syndrome: Diagnosis, Management, and Disease Pathogenesis.

Karakaya B, Kaiser Y, van Moorsel CHM, Grunewald J.

Semin Respir Crit Care Med. 2017 Aug;38(4):463-476. doi: 10.1055/s-0037-1602380. Epub 2017 Jul 27. Review. No abstract available.

PMID:
28750461
33.

Common variants of T-cells contribute differently to phenotypic variation in sarcoidosis.

Rivera NV, Hagemann-Jensen M, Ferreira MAR, Kullberg S, Eklund A, Martin NG, Padyukov L, Grunewald J.

Sci Rep. 2017 Jul 17;7(1):5623. doi: 10.1038/s41598-017-05754-7.

34.

Optimization of an Enzymatic Antibody-Drug Conjugation Approach Based on Coenzyme A Analogs.

Grünewald J, Jin Y, Vance J, Read J, Wang X, Wan Y, Zhou H, Ou W, Klock HE, Peters EC, Uno T, Brock A, Geierstanger BH.

Bioconjug Chem. 2017 Jul 19;28(7):1906-1915. doi: 10.1021/acs.bioconjchem.7b00236. Epub 2017 Jun 14.

PMID:
28590752
35.

Pulmonary Extracellular Vesicles as Mediators of Local and Systemic Inflammation.

Wahlund CJE, Eklund A, Grunewald J, Gabrielsson S.

Front Cell Dev Biol. 2017 Apr 26;5:39. doi: 10.3389/fcell.2017.00039. eCollection 2017. Review.

36.

SNP Variants in Major Histocompatibility Complex Are Associated with Sarcoidosis Susceptibility-A Joint Analysis in Four European Populations.

Wolin A, Lahtela EL, Anttila V, Petrek M, Grunewald J, van Moorsel CHM, Eklund A, Grutters JC, Kolek V, Mrazek F, Kishore A, Padyukov L, Pietinalho A, Ronninger M, Seppänen M, Selroos O, Lokki ML.

Front Immunol. 2017 Apr 19;8:422. doi: 10.3389/fimmu.2017.00422. eCollection 2017.

37.

Humoral immune profiling of mycobacterial antigen recognition in sarcoidosis and Löfgren's syndrome using high-content peptide microarrays.

Ferrara G, Valentini D, Rao M, Wahlström J, Grunewald J, Larsson LO, Brighenti S, Dodoo E, Zumla A, Maeurer M.

Int J Infect Dis. 2017 Mar;56:167-175. doi: 10.1016/j.ijid.2017.01.021. Epub 2017 Jan 31.

38.

Clinical career and research: are they mutually exclusive?

Gori T, Grünewald J.

Eur Heart J. 2017 Jan 7;38(2):72-74. doi: 10.1093/eurheartj/ehw608. No abstract available.

PMID:
28158634
39.

Gender differences in the T-cell profiles of the airways in COPD patients associated with clinical phenotypes.

Forsslund H, Yang M, Mikko M, Karimi R, Nyrén S, Engvall B, Grunewald J, Merikallio H, Kaarteenaho R, Wahlström J, Wheelock ÅM, Sköld CM.

Int J Chron Obstruct Pulmon Dis. 2016 Dec 20;12:35-48. doi: 10.2147/COPD.S113625. eCollection 2017.

40.

The lung microbiota in early rheumatoid arthritis and autoimmunity.

Scher JU, Joshua V, Artacho A, Abdollahi-Roodsaz S, Öckinger J, Kullberg S, Sköld M, Eklund A, Grunewald J, Clemente JC, Ubeda C, Segal LN, Catrina AI.

Microbiome. 2016 Nov 17;4(1):60.

41.

Immune cell activation and cytokine release after stimulation of whole blood with pneumococcal C-polysaccharide and capsular polysaccharides.

Sundberg-Kövamees M, Grunewald J, Wahlström J.

Int J Infect Dis. 2016 Nov;52:1-8. doi: 10.1016/j.ijid.2016.07.004. Epub 2016 Jul 18.

42.

Distinctive Regulatory T Cells and Altered Cytokine Profile Locally in the Airways of Young Smokers with Normal Lung Function.

Ostadkarampour M, Müller M, Öckinger J, Kullberg S, Lindén A, Eklund A, Grunewald J, Wahlström J.

PLoS One. 2016 Oct 31;11(10):e0164751. doi: 10.1371/journal.pone.0164751. eCollection 2016.

43.

Expression Profile of Six RNA-Binding Proteins in Pulmonary Sarcoidosis.

Navratilova Z, Novosadova E, Hagemann-Jensen M, Kullberg S, Kolek V, Grunewald J, Petrek M.

PLoS One. 2016 Aug 30;11(8):e0161669. doi: 10.1371/journal.pone.0161669. eCollection 2016.

44.

Pulmonary sarcoidosis is associated with exosomal vitamin D-binding protein and inflammatory molecules.

Martinez-Bravo MJ, Wahlund CJ, Qazi KR, Moulder R, Lukic A, Rådmark O, Lahesmaa R, Grunewald J, Eklund A, Gabrielsson S.

J Allergy Clin Immunol. 2017 Apr;139(4):1186-1194. doi: 10.1016/j.jaci.2016.05.051. Epub 2016 Aug 23.

PMID:
27566455
45.

Sarcoidosis incidence and prevalence: a nationwide register-based assessment in Sweden.

Arkema EV, Grunewald J, Kullberg S, Eklund A, Askling J.

Eur Respir J. 2016 Dec;48(6):1690-1699. doi: 10.1183/13993003.00477-2016. Epub 2016 Jul 28.

46.

Approach for Identifying Human Leukocyte Antigen (HLA)-DR Bound Peptides from Scarce Clinical Samples.

Heyder T, Kohler M, Tarasova NK, Haag S, Rutishauser D, Rivera NV, Sandin C, Mia S, Malmström V, Wheelock ÅM, Wahlström J, Holmdahl R, Eklund A, Zubarev RA, Grunewald J, Ytterberg AJ.

Mol Cell Proteomics. 2016 Sep;15(9):3017-29. doi: 10.1074/mcp.M116.060764. Epub 2016 Jul 24.

47.

T-cell activation and HLA-regulated response to smoking in the deep airways of patients with multiple sclerosis.

Öckinger J, Hagemann-Jensen M, Kullberg S, Engvall B, Eklund A, Grunewald J, Piehl F, Olsson T, Wahlström J.

Clin Immunol. 2016 Aug;169:114-120. doi: 10.1016/j.clim.2016.06.006. Epub 2016 Jun 23.

PMID:
27339331
48.

Elevated levels of FN1 and CCL2 in bronchoalveolar lavage fluid from sarcoidosis patients.

Hamsten C, Wiklundh E, Grönlund H, Schwenk JM, Uhlén M, Eklund A, Nilsson P, Grunewald J, Häggmark-Månberg A.

Respir Res. 2016 Jun 4;17(1):69. doi: 10.1186/s12931-016-0381-0.

49.

Expanded lung T-bet+RORγT+ CD4+ T-cells in sarcoidosis patients with a favourable disease phenotype.

Kaiser Y, Lepzien R, Kullberg S, Eklund A, Smed-Sörensen A, Grunewald J.

Eur Respir J. 2016 Aug;48(2):484-94. doi: 10.1183/13993003.00092-2016. Epub 2016 May 26.

50.

Protein profiles of CCL5, HPGDS, and NPSR1 in plasma reveal association with childhood asthma.

Hamsten C, Häggmark A, Grundström J, Mikus M, Lindskog C, Konradsen JR, Eklund A, Pershagen G, Wickman M, Grunewald J, Melén E, Hedlin G, Nilsson P, van Hage M.

Allergy. 2016 Sep;71(9):1357-61. doi: 10.1111/all.12927. Epub 2016 May 25.

PMID:
27145233

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