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Age-Dependent Changes in Synaptic NMDA Receptor Composition in Adult Human Cortical Neurons.

Pegasiou CM, Zolnourian A, Gomez-Nicola D, Deinhardt K, Nicoll JAR, Ahmed AI, Vajramani G, Grundy P, Verhoog MB, Mansvelder HD, Perry VH, Bulters D, Vargas-Caballero M.

Cereb Cortex. 2020 Mar 17. pii: bhaa052. doi: 10.1093/cercor/bhaa052. [Epub ahead of print]


Imaging Characteristics of Nephrogenic Rests Versus Small Wilms Tumors: A Report From the Children's Oncology Group Study AREN03B2.

Sandberg JK, Chi YY, Smith EA, Servaes S, Hoffer FA, Mullen EA, Perlman EJ, Tornwall B, Ehrlich PF, Geller JI, Grundy PE, Fernandez CV, Dome JS, Khanna G.

AJR Am J Roentgenol. 2020 Mar 11:1-8. doi: 10.2214/AJR.19.22301. [Epub ahead of print]


Activity of Vincristine and Irinotecan in Diffuse Anaplastic Wilms Tumor and Therapy Outcomes of Stage II to IV Disease: Results of the Children's Oncology Group AREN0321 Study.

Daw NC, Chi YY, Kalapurakal JA, Kim Y, Hoffer FA, Geller JI, Perlman EJ, Ehrlich PF, Mullen EA, Warwick AB, Grundy PE, Paulino AC, Gratias E, Ward D, Anderson JR, Khanna G, Tornwall B, Fernandez CV, Dome JS; AREN0321 Study Committee.

J Clin Oncol. 2020 Mar 5:JCO1901265. doi: 10.1200/JCO.19.01265. [Epub ahead of print]


Augmentation of Therapy for Combined Loss of Heterozygosity 1p and 16q in Favorable Histology Wilms Tumor: A Children's Oncology Group AREN0532 and AREN0533 Study Report.

Dix DB, Fernandez CV, Chi YY, Mullen EA, Geller JI, Gratias EJ, Khanna G, Kalapurakal JA, Perlman EJ, Seibel NL, Ehrlich PF, Malogolowkin M, Anderson J, Gastier-Foster J, Shamberger RC, Kim Y, Grundy PE, Dome JS; AREN0532 and AREN0533 study committees.

J Clin Oncol. 2019 Oct 20;37(30):2769-2777. doi: 10.1200/JCO.18.01972. Epub 2019 Aug 26.


Treatment of stage I anaplastic Wilms' tumour: a report from the Children's Oncology Group AREN0321 study.

Daw NC, Chi YY, Kim Y, Mullen EA, Kalapurakal JA, Tian J, Khanna G, Geller JI, Perlman EJ, Ehrlich PF, Warwick AB, Grundy PE, Fernandez CV, Dome JS; AREN0321 Study Committee.

Eur J Cancer. 2019 Sep;118:58-66. doi: 10.1016/j.ejca.2019.05.033. Epub 2019 Jul 17.


A primate-specific short GluN2A-NMDA receptor isoform is expressed in the human brain.

Warming H, Pegasiou CM, Pitera AP, Kariis H, Houghton SD, Kurbatskaya K, Ahmed A, Grundy P, Vajramani G, Bulters D, Altafaj X, Deinhardt K, Vargas-Caballero M.

Mol Brain. 2019 Jul 4;12(1):64. doi: 10.1186/s13041-019-0485-9.


A comparison of two models of follow-up care for adult survivors of childhood cancer.

Reynolds K, Spavor M, Brandelli Y, Kwok C, Li Y, Disciglio M, Carlson LE, Schulte F, Anderson R, Grundy P, Giese-Davis J.

J Cancer Surviv. 2019 Aug;13(4):547-557. doi: 10.1007/s11764-019-00774-w. Epub 2019 Jun 27.


SVM Optimization for Brain Tumor Identification Using Infrared Spectroscopic Samples.

Fabelo H, Ortega S, Casselden E, Loh J, Bulstrode H, Zolnourian A, Grundy P, Callico GM, Bulters D, Sarmiento R.

Sensors (Basel). 2018 Dec 18;18(12). pii: E4487. doi: 10.3390/s18124487.


Impact of Surveillance Imaging Modality on Survival After Recurrence in Patients With Favorable-Histology Wilms Tumor: A Report From the Children's Oncology Group.

Mullen EA, Chi YY, Hibbitts E, Anderson JR, Steacy KJ, Geller JI, Green DM, Khanna G, Malogolowkin MH, Grundy PE, Fernandez CV, Dome JS.

J Clin Oncol. 2018 Oct 18:JCO1800076. doi: 10.1200/JCO.18.00076. [Epub ahead of print]


Impact of cyclophosphamide and etoposide on outcome of clear cell sarcoma of the kidney treated on the National Wilms Tumor Study-5 (NWTS-5).

Seibel NL, Chi YY, Perlman EJ, Tian J, Sun J, Anderson JR, Ritchey ML, Thomas PR, Miser J, Kalapurakal JA, Grundy PE, Green DM.

Pediatr Blood Cancer. 2019 Jan;66(1):e27450. doi: 10.1002/pbc.27450. Epub 2018 Sep 25.


Corrigendum to "Comparative effectiveness of pediatric integrative medicine as an adjunct to usual care for pediatric inpatients of a North American tertiary care centre: A study protocol for a pragmatic cluster controlled trial" [Contemp. Clin. Trials Commun. (2017) 12-18].

Vohra S, Schlegelmilch M, Jou H, Hartfield D, Mayan M, Ohinmaa A, Wilson B, Spavor M, Grundy P.

Contemp Clin Trials Commun. 2017 Apr 21;6:147. doi: 10.1016/j.conctc.2017.04.004. eCollection 2017 Jun.


Treatment of Stage IV Favorable Histology Wilms Tumor With Lung Metastases: A Report From the Children's Oncology Group AREN0533 Study.

Dix DB, Seibel NL, Chi YY, Khanna G, Gratias E, Anderson JR, Mullen EA, Geller JI, Kalapurakal JA, Paulino AC, Perlman EJ, Ehrlich PF, Malogolowkin M, Gastier-Foster JM, Wagner E, Grundy PE, Fernandez CV, Dome JS.

J Clin Oncol. 2018 Jun 1;36(16):1564-1570. doi: 10.1200/JCO.2017.77.1931. Epub 2018 Apr 16.


Outcome and Prognostic Factors in Stage III Favorable-Histology Wilms Tumor: A Report From the Children's Oncology Group Study AREN0532.

Fernandez CV, Mullen EA, Chi YY, Ehrlich PF, Perlman EJ, Kalapurakal JA, Khanna G, Paulino AC, Hamilton TE, Gow KW, Tochner Z, Hoffer FA, Withycombe JS, Shamberger RC, Kim Y, Geller JI, Anderson JR, Grundy PE, Dome JS.

J Clin Oncol. 2018 Jan 20;36(3):254-261. doi: 10.1200/JCO.2017.73.7999. Epub 2017 Dec 6. Erratum in: J Clin Oncol. 2019 Oct 10;37(29):2710.


Second malignant neoplasms after childhood non-central nervous system embryonal tumours in North America: A population-based study.

Zong X, Pole JD, Grundy PE, Mahmud SM, Parker L, Hung RJ.

Eur J Cancer. 2017 Oct;84:173-183. doi: 10.1016/j.ejca.2017.06.035. Epub 2017 Aug 17.


Interaction of Health Care Worker Health and Safety and Patient Health and Safety in the US Health Care System: Recommendations From the 2016 Summit.

Loeppke R, Boldrighini J, Bowe J, Braun B, Eggins E, Eisenberg BS, Grundy P, Hohn T, Hudson TW, Kannas J Jr, Kapp EA, Konicki D, Larson P, McCutcheon S, McLellan RK, Ording J, Perkins C, Russi M, Stutts C, Yarbrough M.

J Occup Environ Med. 2017 Aug;59(8):803-813. doi: 10.1097/JOM.0000000000001100. No abstract available.


Results of the First Prospective Multi-institutional Treatment Study in Children With Bilateral Wilms Tumor (AREN0534): A Report From the Children's Oncology Group.

Ehrlich P, Chi YY, Chintagumpala MM, Hoffer FA, Perlman EJ, Kalapurakal JA, Warwick A, Shamberger RC, Khanna G, Hamilton TE, Gow KW, Paulino AC, Gratias EJ, Mullen EA, Geller JI, Grundy PE, Fernandez CV, Ritchey ML, Dome JS.

Ann Surg. 2017 Sep;266(3):470-478. doi: 10.1097/SLA.0000000000002356. Erratum in: Ann Surg. 2018 Mar;267(3):e64.


Comparative effectiveness of pediatric integrative medicine as an adjunct to usual care for pediatric inpatients of a North American tertiary care centre: A study protocol for a pragmatic cluster controlled trial.

Vohra S, Schlegelmilch M, Jou H, Hartfield D, Mayan M, Ohinmaa A, Wilson B, Spavor M, Grundy P.

Contemp Clin Trials Commun. 2016 Nov 23;5:12-18. doi: 10.1016/j.conctc.2016.11.002. eCollection 2017 Mar. Erratum in: Contemp Clin Trials Commun. 2017 Apr 21;6:147.


Clinical Outcome and Biological Predictors of Relapse After Nephrectomy Only for Very Low-risk Wilms Tumor: A Report From Children's Oncology Group AREN0532.

Fernandez CV, Perlman EJ, Mullen EA, Chi YY, Hamilton TE, Gow KW, Ferrer FA, Barnhart DC, Ehrlich PF, Khanna G, Kalapurakal JA, Bocking T, Huff V, Tian J, Geller JI, Grundy PE, Anderson JR, Dome JS, Shamberger RC.

Ann Surg. 2017 Apr;265(4):835-840. doi: 10.1097/SLA.0000000000001716.


Association of Chromosome 1q Gain With Inferior Survival in Favorable-Histology Wilms Tumor: A Report From the Children's Oncology Group.

Gratias EJ, Dome JS, Jennings LJ, Chi YY, Tian J, Anderson J, Grundy P, Mullen EA, Geller JI, Fernandez CV, Perlman EJ.

J Clin Oncol. 2016 Sep 10;34(26):3189-94. doi: 10.1200/JCO.2015.66.1140. Epub 2016 Jul 11.


Genomic imbalances pinpoint potential oncogenes and tumor suppressors in Wilms tumors.

Krepischi ACV, Maschietto M, Ferreira EN, Silva AG, Costa SS, da Cunha IW, Barros BDF, Grundy PE, Rosenberg C, Carraro DM.

Mol Cytogenet. 2016 Feb 24;9:20. doi: 10.1186/s13039-016-0227-y. eCollection 2016.


Leveraging the principles of osteopathic medicine to improve diabetes outcomes within a new era of health care reform.

Ciervo CA, Shubrook JH, Grundy P.

J Am Osteopath Assoc. 2015 Apr;115(4 Suppl):eS8-eS19. doi: 10.7556/jaoa.2015.058. Review.


Diabetes management within evolving health care delivery models: the osteopathic perspective.

Ciervo CA, Shubrook JH, Grundy P.

J Am Osteopath Assoc. 2015 Apr;115(4 Suppl):eS5-7. doi: 10.7556/jaoa.2015.057. Review. No abstract available.


Novel association between microglia and stem cells in human gliomas: A contributor to tumour proliferation?

Noorani I, Petty G, Grundy PL, Sharpe G, Willaime-Morawek S, Harris S, Thomas GJ, Nicoll JA, Boche D.

J Pathol Clin Res. 2015 Jan 14;1(2):67-75. doi: 10.1002/cjp2.7. eCollection 2015 Apr.


TP53 mutational status is a potential marker for risk stratification in Wilms tumour with diffuse anaplasia.

Maschietto M, Williams RD, Chagtai T, Popov SD, Sebire NJ, Vujanic G, Perlman E, Anderson JR, Grundy P, Dome JS, Pritchard-Jones K.

PLoS One. 2014 Oct 14;9(10):e109924. doi: 10.1371/journal.pone.0109924. eCollection 2014.


Phenytoin-induced methaemoglobinaemia in a patient with glioblastoma multiforme.

Noorani I, Durnford A, Sadek AR, Charalambides C, Grundy P.

Br J Neurosurg. 2015 Feb;29(1):112. doi: 10.3109/02688697.2014.950635. Epub 2014 Aug 19. No abstract available.


Recurrent somatic mutation in DROSHA induces microRNA profile changes in Wilms tumour.

Torrezan GT, Ferreira EN, Nakahata AM, Barros BD, Castro MT, Correa BR, Krepischi AC, Olivieri EH, Cunha IW, Tabori U, Grundy PE, Costa CM, de Camargo B, Galante PA, Carraro DM.

Nat Commun. 2014 Jun 9;5:4039. doi: 10.1038/ncomms5039.


Delayed post-operative haemorrhage after carmustine wafer implantation: a case series from two UK centres.

Shah RS, Homapour B, Casselden E, Barr JG, Grundy PL, Brydon HL.

Br J Neurosurg. 2014 Aug;28(4):488-94. doi: 10.3109/02688697.2013.861387. Epub 2013 Dec 9.


CAM and Pediatric Oncology: Where Are All the Best Cases?

Adams D, Spelliscy C, Sivakumar L, Grundy P, Leis A, Sencer S, Vohra S.

Evid Based Complement Alternat Med. 2013;2013:632351. doi: 10.1155/2013/632351. Epub 2013 Aug 25.


Outcome of patients with Stage II/favorable histology Wilms tumor with and without local tumor spill: a report from the National Wilms Tumor Study Group.

Green DM, Breslow NE, D'Angio GJ, Malogolowkin MH, Ritchey ML, Evans AE, Beckwith JB, Perlman EJ, Shamberger RC, Peterson S, Grundy PE, Dome JS, Thomas PR, Kalapurakal JA.

Pediatr Blood Cancer. 2014 Jan;61(1):134-9. doi: 10.1002/pbc.24658. Epub 2013 Aug 23.


Gain of 1q is associated with inferior event-free and overall survival in patients with favorable histology Wilms tumor: a report from the Children's Oncology Group.

Gratias EJ, Jennings LJ, Anderson JR, Dome JS, Grundy P, Perlman EJ.

Cancer. 2013 Nov 1;119(21):3887-94. doi: 10.1002/cncr.28239. Epub 2013 Aug 26.


Protecting the culture of a patient-centered medical home.

Dorrance KA, Ramchandani S, LaRochelle J, Mael F, Lynch S, Grundy P.

Mil Med. 2013 Feb;178(2):153-8.


Effectiveness and outcomes of surgery for cerebral metastases.

Lim CS, Grundy PL.

Br J Neurosurg. 2013 Oct;27(5):654-7. doi: 10.3109/02688697.2013.771729. Epub 2013 Mar 5.


New policies to address the global burden of childhood cancers.

Sullivan R, Kowalczyk JR, Agarwal B, Ladenstein R, Fitzgerald E, Barr R, Steliarova-Foucher E, Magrath I, Howard SC, Kruger M, Valsecchi MG, Biondi A, Grundy P, Smith MA, Adamson P, Vassal G, Pritchard-Jones K.

Lancet Oncol. 2013 Mar;14(3):e125-35. doi: 10.1016/S1470-2045(13)70007-X. Epub 2013 Feb 20. Review.


Clinicopathologic findings predictive of relapse in children with stage III favorable-histology Wilms tumor.

Ehrlich PF, Anderson JR, Ritchey ML, Dome JS, Green DM, Grundy PE, Perlman EJ, Kalapurakal JA, Breslow NE, Shamberger RC.

J Clin Oncol. 2013 Mar 20;31(9):1196-201. doi: 10.1200/JCO.2011.41.1165. Epub 2013 Feb 4.


Primary nephrectomy and intraoperative tumor spill: report from the Children's Oncology Group (COG) renal tumors committee.

Gow KW, Barnhart DC, Hamilton TE, Kandel JJ, Chen MK, Ferrer FA, Price MR, Mullen EA, Geller JI, Gratias EJ, Rosen N, Khanna G, Naranjo A, Ritchey ML, Grundy PE, Dome JS, Ehrlich PF.

J Pediatr Surg. 2013 Jan;48(1):34-8. doi: 10.1016/j.jpedsurg.2012.10.015.


Infantile myofibromatosis: report on a family with autosomal dominant inheritance and variable penetrance.

Kulkarni K, Desai S, Grundy P, Sergi C.

J Pediatr Surg. 2012 Dec;47(12):2312-5. doi: 10.1016/j.jpedsurg.2012.09.046.


Detection of preoperative wilms tumor rupture with CT: a report from the Children's Oncology Group.

Khanna G, Naranjo A, Hoffer F, Mullen E, Geller J, Gratias EJ, Ehrlich PF, Perlman EJ, Rosen N, Grundy P, Dome JS.

Radiology. 2013 Feb;266(2):610-7. doi: 10.1148/radiol.12120670. Epub 2012 Nov 28.


B7-h1 as a biomarker for therapy failure in patients with favorable histology Wilms tumor.

Routh JC, Grundy PE, Anderson JR, Retik AB, Kurek KC.

J Urol. 2013 Apr;189(4):1487-92. doi: 10.1016/j.juro.2012.11.012. Epub 2012 Nov 12.


Use of gemcitabine with multi-stage surgical resection as successful second-line treatment of metastatic pancreatoblastoma.

Belletrutti MJ, Bigam D, Bhargava R, Grundy P.

J Pediatr Hematol Oncol. 2013 Jan;35(1):e7-10. doi: 10.1097/MPH.0b013e3182707577.


Clinically relevant subsets identified by gene expression patterns support a revised ontogenic model of Wilms tumor: a Children's Oncology Group Study.

Gadd S, Huff V, Huang CC, Ruteshouser EC, Dome JS, Grundy PE, Breslow N, Jennings L, Green DM, Beckwith JB, Perlman EJ.

Neoplasia. 2012 Aug;14(8):742-56.


Transforming care delivery. Interview by Bob Kehoe.

Grundy P.

Hosp Health Netw. 2012 May;86(5):30-1. No abstract available.


The effects of the NICE Technology Appraisal 121 (gliadel and temozolomide) on survival in high-grade glioma.

Barr JG, Grundy PL.

Br J Neurosurg. 2012 Dec;26(6):818-22. doi: 10.3109/02688697.2012.697221. Epub 2012 Jun 21.


Outcomes of patients with revised stage I clear cell sarcoma of kidney treated in National Wilms Tumor Studies 1-5.

Kalapurakal JA, Perlman EJ, Seibel NL, Ritchey M, Dome JS, Grundy PE.

Int J Radiat Oncol Biol Phys. 2013 Feb 1;85(2):428-31. doi: 10.1016/j.ijrobp.2012.04.023. Epub 2012 Jun 1.


Magneto-optical stokes polarimetry and nanostructured magnetic materials.

Cook PJ, Zhang J, Liu Y, Guan W, Wang N, Qin L, Shen TH, Jones GA, Grundy PJ.

J Nanosci Nanotechnol. 2012 Feb;12(2):1067-73.


A genome-wide association study identifies susceptibility loci for Wilms tumor.

Turnbull C, Perdeaux ER, Pernet D, Naranjo A, Renwick A, Seal S, Munoz-Xicola RM, Hanks S, Slade I, Zachariou A, Warren-Perry M, Ruark E, Gerrard M, Hale J, Hewitt M, Kohler J, Lane S, Levitt G, Madi M, Morland B, Neefjes V, Nicholson J, Picton S, Pizer B, Ronghe M, Stevens M, Traunecker H, Stiller CA, Pritchard-Jones K, Dome J, Grundy P, Rahman N.

Nat Genet. 2012 Apr 29;44(6):681-4. doi: 10.1038/ng.2251. Erratum in: Nat Genet. 2013 Aug;45(8):962.


NICE guidance on the use of carmustine wafers in high grade gliomas: a national study on variation in practice.

Price SJ, Whittle IR, Ashkan K, Grundy P, Cruickshank G; UK-HGG Study Group.

Br J Neurosurg. 2012 Jun;26(3):331-5. doi: 10.3109/02688697.2012.673651. Epub 2012 Apr 6.


Stratification of Wilms tumor by genetic and epigenetic analysis.

Scott RH, Murray A, Baskcomb L, Turnbull C, Loveday C, Al-Saadi R, Williams R, Breatnach F, Gerrard M, Hale J, Kohler J, Lapunzina P, Levitt GA, Picton S, Pizer B, Ronghe MD, Traunecker H, Williams D, Kelsey A, Vujanic GM, Sebire NJ, Grundy P, Stiller CA, Pritchard-Jones K, Douglas J, Rahman N.

Oncotarget. 2012 Mar;3(3):327-35.


Optimizing health care delivery by integrating workplaces, homes, and communities: how occupational and environmental medicine can serve as a vital connecting link between accountable care organizations and the patient-centered medical home.

McLellan RK, Sherman B, Loeppke RR, McKenzie J, Mueller KL, Yarborough CM, Grundy P, Allen H, Larson PW.

J Occup Environ Med. 2012 Apr;54(4):504-12. doi: 10.1097/JOM.0b013e31824fe0aa.


Clinical significance of pulmonary nodules detected by CT and Not CXR in patients treated for favorable histology Wilms tumor on national Wilms tumor studies-4 and -5: a report from the Children's Oncology Group.

Grundy PE, Green DM, Dirks AC, Berendt AE, Breslow NE, Anderson JR, Dome JS.

Pediatr Blood Cancer. 2012 Oct;59(4):631-5. doi: 10.1002/pbc.24123. Epub 2012 Mar 15.


Temporal blastemal cell gene expression analysis in the kidney reveals new Wnt and related signaling pathway genes to be essential for Wilms' tumor onset.

Maschietto M, Trapé AP, Piccoli FS, Ricca TI, Dias AA, Coudry RA, Galante PA, Torres C, Fahhan L, Lourenço S, Grundy PE, de Camargo B, de Souza S, Neves EJ, Soares FA, Brentani H, Carraro DM.

Cell Death Dis. 2011 Nov 3;2:e224. doi: 10.1038/cddis.2011.105.

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