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Items: 1 to 50 of 90

1.

The acidic protein rich in leucines Anp32b is an immunomodulator of inflammation in mice.

Chemnitz J, Pieper D, Stich L, Schumacher U, Balabanov S, Spohn M, Grundhoff A, Steinkasserer A, Hauber J, Zinser E.

Sci Rep. 2019 Mar 19;9(1):4853. doi: 10.1038/s41598-019-41269-z.

2.

Repression of Human Papillomavirus Oncogene Expression under Hypoxia Is Mediated by PI3K/mTORC2/AKT Signaling.

Bossler F, Kuhn BJ, Günther T, Kraemer SJ, Khalkar P, Adrian S, Lohrey C, Holzer A, Shimobayashi M, Dürst M, Mayer A, Rösl F, Grundhoff A, Krijgsveld J, Hoppe-Seyler K, Hoppe-Seyler F.

MBio. 2019 Feb 12;10(1). pii: e02323-18. doi: 10.1128/mBio.02323-18.

3.

Piscine Orthoreovirus 3 Is Not the Causative Pathogen of Proliferative Darkening Syndrome (PDS) of Brown Trout (Salmo trutta fario).

Fux R, Arndt D, Langenmayer MC, Schwaiger J, Ferling H, Fischer N, Indenbirken D, Grundhoff A, Dölken L, Adamek M, Steinhagen D, Sutter G.

Viruses. 2019 Jan 28;11(2). pii: E112. doi: 10.3390/v11020112.

4.

Identification of a novel clade of group A rotaviruses in fatally diseased domestic pigeons in Europe.

Rubbenstroth D, Peus E, Schramm E, Kottmann D, Bartels H, McCowan C, Schulze C, Akimkin V, Fischer N, Wylezich C, Hlinak A, Spadinger A, Großmann E, Petersen H, Grundhoff A, Rautenschlein S, Teske L.

Transbound Emerg Dis. 2019 Jan;66(1):552-561. doi: 10.1111/tbed.13065. Epub 2018 Nov 28.

PMID:
30407742
5.

TDP-43 enhances translation of specific mRNAs linked to neurodegenerative disease.

Neelagandan N, Gonnella G, Dang S, Janiesch PC, Miller KK, Küchler K, Marques RF, Indenbirken D, Alawi M, Grundhoff A, Kurtz S, Duncan KE.

Nucleic Acids Res. 2019 Jan 10;47(1):341-361. doi: 10.1093/nar/gky972.

6.

Dynamic changes of circulating miRNAs induced by the Ebola virus vaccine VSV-EBOV.

Fischer T, Spohn M, Olearo F, Zinser ME, Kasonta R, Stubbe HC, Rechtien A, Ly ML, Schmiedel S, Lohse AW, Grundhoff A; VEBCON (VSV-Ebola Consortium), Addo MM, Dahlke C.

Vaccine. 2018 Nov 12;36(46):7083-7094. doi: 10.1016/j.vaccine.2018.09.016. Epub 2018 Sep 21.

PMID:
30244872
7.

Identification of virus-encoded microRNAs in divergent Papillomaviruses.

Chirayil R, Kincaid RP, Dahlke C, Kuny CV, Dälken N, Spohn M, Lawson B, Grundhoff A, Sullivan CS.

PLoS Pathog. 2018 Jul 26;14(7):e1007156. doi: 10.1371/journal.ppat.1007156. eCollection 2018 Jul.

8.

T-Cell Receptor Diversity and the Control of T-Cell Homeostasis Mark Ebola Virus Disease Survival in Humans.

Speranza E, Ruibal P, Port JR, Feng F, Burkhardt L, Grundhoff A, Günther S, Oestereich L, Hiscox JA, Connor JH, Muñoz-Fontela C.

J Infect Dis. 2018 Nov 22;218(suppl_5):S508-S518. doi: 10.1093/infdis/jiy352.

PMID:
29986035
9.

Generation of a novel next-generation sequencing-based method for the isolation of new human papillomavirus types.

Brancaccio RN, Robitaille A, Dutta S, Cuenin C, Santare D, Skenders G, Leja M, Fischer N, Giuliano AR, Rollison DE, Grundhoff A, Tommasino M, Gheit T.

Virology. 2018 Jul;520:1-10. doi: 10.1016/j.virol.2018.04.017. Epub 2018 May 7.

PMID:
29747121
10.

High Abundance and Genetic Variability of Atypical Porcine Pestivirus in Pigs from Europe and Asia.

Postel A, Meyer D, Cagatay GN, Feliziani F, De Mia GM, Fischer N, Grundhoff A, Milićević V, Deng MC, Chang CY, Qiu HJ, Sun Y, Wendt M, Becher P.

Emerg Infect Dis. 2017 Dec;23(12):2104-2107. doi: 10.3201/eid2312.170951.

11.

Insights into Microalga and Bacteria Interactions of Selected Phycosphere Biofilms Using Metagenomic, Transcriptomic, and Proteomic Approaches.

Krohn-Molt I, Alawi M, Förstner KU, Wiegandt A, Burkhardt L, Indenbirken D, Thieß M, Grundhoff A, Kehr J, Tholey A, Streit WR.

Front Microbiol. 2017 Oct 10;8:1941. doi: 10.3389/fmicb.2017.01941. eCollection 2017.

12.

Complete Genome Sequence of a Novel Human Gammapapillomavirus Isolated from Skin.

Brancaccio RN, Robitaille A, Dutta S, Rollison DE, Fischer N, Grundhoff A, Tommasino M, Gheit T.

Genome Announc. 2017 Aug 24;5(34). pii: e00833-17. doi: 10.1128/genomeA.00833-17.

13.

Epigenetic manipulation of host chromatin by Kaposi sarcoma-associated herpesvirus: a tumor-promoting factor?

Günther T, Grundhoff A.

Curr Opin Virol. 2017 Oct;26:104-111. doi: 10.1016/j.coviro.2017.07.018. Epub 2017 Aug 9. Review.

PMID:
28802146
14.

Persistent KSHV Infection Increases EBV-Associated Tumor Formation In Vivo via Enhanced EBV Lytic Gene Expression.

McHugh D, Caduff N, Barros MHM, Rämer PC, Raykova A, Murer A, Landtwing V, Quast I, Styles CT, Spohn M, Fowotade A, Delecluse HJ, Papoudou-Bai A, Lee YM, Kim JM, Middeldorp J, Schulz TF, Cesarman E, Zbinden A, Capaul R, White RE, Allday MJ, Niedobitek G, Blackbourn DJ, Grundhoff A, Münz C.

Cell Host Microbe. 2017 Jul 12;22(1):61-73.e7. doi: 10.1016/j.chom.2017.06.009.

15.

Recovery of the first full-length genome sequence of a parapoxvirus directly from a clinical sample.

Günther T, Haas L, Alawi M, Wohlsein P, Marks J, Grundhoff A, Becher P, Fischer N.

Sci Rep. 2017 Jun 16;7(1):3734. doi: 10.1038/s41598-017-03997-y.

16.

Spontaneous lung metastasis formation of human Merkel cell carcinoma cell lines transplanted into scid mice.

Knips J, Czech-Sioli M, Spohn M, Heiland M, Moll I, Grundhoff A, Schumacher U, Fischer N.

Int J Cancer. 2017 Jul 1;141(1):160-171. doi: 10.1002/ijc.30723. Epub 2017 Apr 21.

17.

Novel poly-uridine insertion in the 3'UTR and E2 amino acid substitutions in a low virulent classical swine fever virus.

Coronado L, Liniger M, Muñoz-González S, Postel A, Pérez LJ, Pérez-Simó M, Perera CL, Frías-Lepoureau MT, Rosell R, Grundhoff A, Indenbirken D, Alawi M, Fischer N, Becher P, Ruggli N, Ganges L.

Vet Microbiol. 2017 Mar;201:103-112. doi: 10.1016/j.vetmic.2017.01.013. Epub 2017 Jan 17.

PMID:
28284595
18.

Pregnancy-Related Immune Adaptation Promotes the Emergence of Highly Virulent H1N1 Influenza Virus Strains in Allogenically Pregnant Mice.

Engels G, Hierweger AM, Hoffmann J, Thieme R, Thiele S, Bertram S, Dreier C, Resa-Infante P, Jacobsen H, Thiele K, Alawi M, Indenbirken D, Grundhoff A, Siebels S, Fischer N, Stojanovska V, Muzzio D, Jensen F, Karimi K, Mittrücker HW, Arck PC, Gabriel G.

Cell Host Microbe. 2017 Mar 8;21(3):321-333. doi: 10.1016/j.chom.2017.02.020.

19.

RNF40 regulates gene expression in an epigenetic context-dependent manner.

Xie W, Nagarajan S, Baumgart SJ, Kosinsky RL, Najafova Z, Kari V, Hennion M, Indenbirken D, Bonn S, Grundhoff A, Wegwitz F, Mansouri A, Johnsen SA.

Genome Biol. 2017 Feb 16;18(1):32. doi: 10.1186/s13059-017-1159-5.

20.

Successful retreatment of a patient with chronic hepatitis C genotype 2k/1b virus with ombitasvir/paritaprevir/ritonavir plus dasabuvir.

Todt D, Schlevogt B, Deterding K, Grundhoff A, Manns MP, Wedemeyer H, Fischer N, Cornberg M, Steinmann E.

J Antimicrob Chemother. 2017 May 1;72(5):1541-1543. doi: 10.1093/jac/dkw572. No abstract available.

PMID:
28100444
21.

BRD4 promotes p63 and GRHL3 expression downstream of FOXO in mammary epithelial cells.

Nagarajan S, Bedi U, Budida A, Hamdan FH, Mishra VK, Najafova Z, Xie W, Alawi M, Indenbirken D, Knapp S, Chiang CM, Grundhoff A, Kari V, Scheel CH, Wegwitz F, Johnsen SA.

Nucleic Acids Res. 2017 Apr 7;45(6):3130-3145. doi: 10.1093/nar/gkw1276.

22.

First report of Escherichia coli co-producing NDM-1 and OXA-232.

Both A, Huang J, Kaase M, Hezel J, Wertheimer D, Fenner I, Günther T, Grundhoff A, Büttner H, Aepfelbacher M, Rohde H, Hentschke M.

Diagn Microbiol Infect Dis. 2016 Dec;86(4):437-438. doi: 10.1016/j.diagmicrobio.2016.09.005. Epub 2016 Sep 16.

PMID:
27681362
23.

Indication of Horizontal DNA Gene Transfer by Extracellular Vesicles.

Fischer S, Cornils K, Speiseder T, Badbaran A, Reimer R, Indenbirken D, Grundhoff A, Brunswig-Spickenheier B, Alawi M, Lange C.

PLoS One. 2016 Sep 29;11(9):e0163665. doi: 10.1371/journal.pone.0163665. eCollection 2016.

24.

Replication of Merkel cell polyomavirus induces reorganization of promyelocytic leukemia nuclear bodies.

Neumann F, Czech-Sioli M, Dobner T, Grundhoff A, Schreiner S, Fischer N.

J Gen Virol. 2016 Nov;97(11):2926-2938. doi: 10.1099/jgv.0.000593. Epub 2016 Aug 30.

PMID:
27580912
25.

Suspected encephalitis with Candida tropicalis and Fusarium detected by unbiased RNA sequencing.

Christopeit M, Grundhoff A, Rohde H, Belmar-Campos C, Grzyska U, Fiehler J, Wolschke C, Ayuk F, Kröger N, Fischer N.

Ann Hematol. 2016 Oct;95(11):1919-21. doi: 10.1007/s00277-016-2770-3. Epub 2016 Jul 29. No abstract available.

PMID:
27468852
26.

Pegivirus Infection in Domestic Pigs, Germany.

Baechlein C, Grundhoff A, Fischer N, Alawi M, Hoeltig D, Waldmann KH, Becher P.

Emerg Infect Dis. 2016 Jul;22(7):1312-4. doi: 10.3201/eid2207.160024. No abstract available.

27.

Immunosuppressive Yersinia Effector YopM Binds DEAD Box Helicase DDX3 to Control Ribosomal S6 Kinase in the Nucleus of Host Cells.

Berneking L, Schnapp M, Rumm A, Trasak C, Ruckdeschel K, Alawi M, Grundhoff A, Kikhney AG, Koch-Nolte F, Buck F, Perbandt M, Betzel C, Svergun DI, Hentschke M, Aepfelbacher M.

PLoS Pathog. 2016 Jun 14;12(6):e1005660. doi: 10.1371/journal.ppat.1005660. eCollection 2016 Jun.

28.

Presence of atypical porcine pestivirus (APPV) genomes in newborn piglets correlates with congenital tremor.

Postel A, Hansmann F, Baechlein C, Fischer N, Alawi M, Grundhoff A, Derking S, Tenhündfeld J, Pfankuche VM, Herder V, Baumgärtner W, Wendt M, Becher P.

Sci Rep. 2016 Jun 13;6:27735. doi: 10.1038/srep27735.

29.

Deep metagenome and metatranscriptome analyses of microbial communities affiliated with an industrial biogas fermenter, a cow rumen, and elephant feces reveal major differences in carbohydrate hydrolysis strategies.

Güllert S, Fischer MA, Turaev D, Noebauer B, Ilmberger N, Wemheuer B, Alawi M, Rattei T, Daniel R, Schmitz RA, Grundhoff A, Streit WR.

Biotechnol Biofuels. 2016 Jun 7;9:121. doi: 10.1186/s13068-016-0534-x. eCollection 2016.

30.

Histone Chaperone SSRP1 is Essential for Wnt Signaling Pathway Activity During Osteoblast Differentiation.

Hossan T, Nagarajan S, Baumgart SJ, Xie W, Magallanes RT, Hernandez C, Chiaroni PM, Indenbirken D, Spitzner M, Thomas-Chollier M, Grade M, Thieffry D, Grundhoff A, Wegwitz F, Johnsen SA.

Stem Cells. 2016 May;34(5):1369-76. doi: 10.1002/stem.2287. Epub 2016 Feb 13.

31.

A transplant "immunome" screening platform defines a targetable epitope fingerprint of multiple myeloma.

Schieferdecker A, Oberle A, Thiele B, Hofmann F, Göthel M, Miethe S, Hust M, Braig F, Voigt M, von Pein UM, Koch-Nolte F, Haag F, Alawi M, Indenbirken D, Grundhoff A, Bokemeyer C, Bacher U, Kröger N, Binder M.

Blood. 2016 Jun 23;127(25):3202-14. doi: 10.1182/blood-2015-10-676536. Epub 2016 Mar 31.

32.

Role of Clinicogenomics in Infectious Disease Diagnostics and Public Health Microbiology.

Westblade LF, van Belkum A, Grundhoff A, Weinstock GM, Pamer EG, Pallen MJ, Dunne WM Jr.

J Clin Microbiol. 2016 Jul;54(7):1686-1693. doi: 10.1128/JCM.02664-15. Epub 2016 Feb 24.

33.

Functional Dissection of an Alternatively Spliced Herpesvirus Gene by Splice Site Mutagenesis.

Schommartz T, Loroch S, Alawi M, Grundhoff A, Sickmann A, Brune W.

J Virol. 2016 Apr 14;90(9):4626-4636. doi: 10.1128/JVI.02987-15. Print 2016 May.

34.

Directed evolution of a recombinase that excises the provirus of most HIV-1 primary isolates with high specificity.

Karpinski J, Hauber I, Chemnitz J, Schäfer C, Paszkowski-Rogacz M, Chakraborty D, Beschorner N, Hofmann-Sieber H, Lange UC, Grundhoff A, Hackmann K, Schrock E, Abi-Ghanem J, Pisabarro MT, Surendranath V, Schambach A, Lindner C, van Lunzen J, Hauber J, Buchholz F.

Nat Biotechnol. 2016 Apr;34(4):401-9. doi: 10.1038/nbt.3467. Epub 2016 Feb 22.

PMID:
26900663
35.

Investigation of Viral and Host Chromatin by ChIP-PCR or ChIP-Seq Analysis.

Günther T, Theiss JM, Fischer N, Grundhoff A.

Curr Protoc Microbiol. 2016 Feb 8;40:1E.10.1-21. doi: 10.1002/9780471729259.mc01e10s40.

PMID:
26855283
36.

Merkel cell polyomavirus, a highly prevalent virus with tumorigenic potential.

Grundhoff A, Fischer N.

Curr Opin Virol. 2015 Oct;14:129-37. doi: 10.1016/j.coviro.2015.08.010. Review.

PMID:
26447560
37.

CRISPR/Cas9 nickase-mediated disruption of hepatitis B virus open reading frame S and X.

Karimova M, Beschorner N, Dammermann W, Chemnitz J, Indenbirken D, Bockmann JH, Grundhoff A, Lüth S, Buchholz F, Schulze zur Wiesch J, Hauber J.

Sci Rep. 2015 Sep 3;5:13734. doi: 10.1038/srep13734.

38.

In Vitro Replication Assay for Merkel Cell Polyomavirus (MCPyV).

Neumann F, Czech-Sioli M, Grundhoff A, Fischer N.

Curr Protoc Microbiol. 2015 Aug 3;38:14F.2.1-19. doi: 10.1002/9780471729259.mc14f02s38.

PMID:
26237107
39.

A Comprehensive Analysis of Replicating Merkel Cell Polyomavirus Genomes Delineates the Viral Transcription Program and Suggests a Role for mcv-miR-M1 in Episomal Persistence.

Theiss JM, Günther T, Alawi M, Neumann F, Tessmer U, Fischer N, Grundhoff A.

PLoS Pathog. 2015 Jul 28;11(7):e1004974. doi: 10.1371/journal.ppat.1004974. eCollection 2015 Jul.

40.

Epidermal growth factor receptor mutation mediates cross-resistance to panitumumab and cetuximab in gastrointestinal cancer.

Braig F, März M, Schieferdecker A, Schulte A, Voigt M, Stein A, Grob T, Alawi M, Indenbirken D, Kriegs M, Engel E, Vanhoefer U, Grundhoff A, Loges S, Riecken K, Fehse B, Bokemeyer C, Binder M.

Oncotarget. 2015 May 20;6(14):12035-47.

41.

Evaluation of Unbiased Next-Generation Sequencing of RNA (RNA-seq) as a Diagnostic Method in Influenza Virus-Positive Respiratory Samples.

Fischer N, Indenbirken D, Meyer T, Lütgehetmann M, Lellek H, Spohn M, Aepfelbacher M, Alawi M, Grundhoff A.

J Clin Microbiol. 2015 Jul;53(7):2238-50. doi: 10.1128/JCM.02495-14. Epub 2015 May 13.

42.

Identification of a Novel Hepacivirus in Domestic Cattle from Germany.

Baechlein C, Fischer N, Grundhoff A, Alawi M, Indenbirken D, Postel A, Baron AL, Offinger J, Becker K, Beineke A, Rehage J, Becher P.

J Virol. 2015 Jul;89(14):7007-15. doi: 10.1128/JVI.00534-15. Epub 2015 Apr 29.

43.

Close relationship of ruminant pestiviruses and classical Swine Fever virus.

Postel A, Schmeiser S, Oguzoglu TC, Indenbirken D, Alawi M, Fischer N, Grundhoff A, Becher P.

Emerg Infect Dis. 2015 Apr;21(4):668-72. doi: 10.3201/eid2104.141441.

44.

Highly divergent hepaciviruses from African cattle.

Corman VM, Grundhoff A, Baechlein C, Fischer N, Gmyl A, Wollny R, Dei D, Ritz D, Binger T, Adankwah E, Marfo KS, Annison L, Annan A, Adu-Sarkodie Y, Oppong S, Becher P, Drosten C, Drexler JF.

J Virol. 2015 Jun;89(11):5876-82. doi: 10.1128/JVI.00393-15. Epub 2015 Mar 18.

45.

Generation of high-titre virus stocks using BrK.219, a B-cell line infected stably with recombinant Kaposi's sarcoma-associated herpesvirus.

Kati S, Hage E, Mynarek M, Ganzenmueller T, Indenbirken D, Grundhoff A, Schulz TF.

J Virol Methods. 2015 Jun 1;217:79-86. doi: 10.1016/j.jviromet.2015.02.022. Epub 2015 Feb 28.

PMID:
25736227
46.

Complete genome sequence of Pig-tailed macaque rhadinovirus 2 and its evolutionary relationship with rhesus macaque rhadinovirus and human herpesvirus 8/Kaposi's sarcoma-associated herpesvirus.

Bruce AG, Thouless ME, Haines AS, Pallen MJ, Grundhoff A, Rose TM.

J Virol. 2015 Apr;89(7):3888-909. doi: 10.1128/JVI.03597-14. Epub 2015 Jan 21.

47.

A comparative metagenome survey of the fecal microbiota of a breast- and a plant-fed Asian elephant reveals an unexpectedly high diversity of glycoside hydrolase family enzymes.

Ilmberger N, Güllert S, Dannenberg J, Rabausch U, Torres J, Wemheuer B, Alawi M, Poehlein A, Chow J, Turaev D, Rattei T, Schmeisser C, Salomon J, Olsen PB, Daniel R, Grundhoff A, Borchert MS, Streit WR.

PLoS One. 2014 Sep 10;9(9):e106707. doi: 10.1371/journal.pone.0106707. eCollection 2014.

48.

Influence of ND10 components on epigenetic determinants of early KSHV latency establishment.

Günther T, Schreiner S, Dobner T, Tessmer U, Grundhoff A.

PLoS Pathog. 2014 Jul 17;10(7):e1004274. doi: 10.1371/journal.ppat.1004274. eCollection 2014 Jul.

49.

Bromodomain protein BRD4 is required for estrogen receptor-dependent enhancer activation and gene transcription.

Nagarajan S, Hossan T, Alawi M, Najafova Z, Indenbirken D, Bedi U, Taipaleenmäki H, Ben-Batalla I, Scheller M, Loges S, Knapp S, Hesse E, Chiang CM, Grundhoff A, Johnsen SA.

Cell Rep. 2014 Jul 24;8(2):460-9. doi: 10.1016/j.celrep.2014.06.016. Epub 2014 Jul 10.

50.

Complete genome sequence of pronghorn virus, a pestivirus.

Neill JD, Ridpath JF, Fischer N, Grundhoff A, Postel A, Becher P.

Genome Announc. 2014 Jun 12;2(3). pii: e00575-14. doi: 10.1128/genomeA.00575-14.

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