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Items: 1 to 50 of 162

1.

Genetic Characterization and Zoonotic Potential of Highly Pathogenic Avian Influenza Virus A(H5N6/H5N5), Germany, 2017-2018.

Pohlmann A, Hoffmann D, Grund C, Koethe S, Hüssy D, Meier SM, King J, Schinköthe J, Ulrich R, Harder T, Beer M.

Emerg Infect Dis. 2019 Oct;25(10):1973-1976. doi: 10.3201/eid2510.181931.

2.

Updated unified phylogenetic classification system and revised nomenclature for Newcastle disease virus.

Dimitrov KM, Abolnik C, Afonso CL, Albina E, Bahl J, Berg M, Briand FX, Brown IH, Choi KS, Chvala I, Diel DG, Durr PA, Ferreira HL, Fusaro A, Gil P, Goujgoulova GV, Grund C, Hicks JT, Joannis TM, Torchetti MK, Kolosov S, Lambrecht B, Lewis NS, Liu H, Liu H, McCullough S, Miller PJ, Monne I, Muller CP, Munir M, Reischak D, Sabra M, Samal SK, Servan de Almeida R, Shittu I, Snoeck CJ, Suarez DL, Van Borm S, Wang Z, Wong FYK.

Infect Genet Evol. 2019 Oct;74:103917. doi: 10.1016/j.meegid.2019.103917. Epub 2019 Jun 11.

3.

Investigation of suspected Newcastle disease (ND) outbreaks in Egypt uncovers a high virus velogenic ND virus burden in small-scale holdings and the presence of multiple pathogens.

Moharam I, Razik AAE, Sultan H, Ghezlan M, Meseko C, Franzke K, Harder T, Beer M, Grund C.

Avian Pathol. 2019 Oct;48(5):406-415. doi: 10.1080/03079457.2019.1612852. Epub 2019 Jul 25.

PMID:
31090444
4.

A novel European H5N8 influenza A virus has increased virulence in ducks but low zoonotic potential.

Grund C, Hoffmann D, Ulrich R, Naguib M, Schinköthe J, Hoffmann B, Harder T, Saenger S, Zscheppang K, Tönnies M, Hippenstiel S, Hocke A, Wolff T, Beer M.

Emerg Microbes Infect. 2018 Jul 19;7(1):132. doi: 10.1038/s41426-018-0130-1.

5.

From low to high pathogenicity-Characterization of H7N7 avian influenza viruses in two epidemiologically linked outbreaks.

Dietze K, Graaf A, Homeier-Bachmann T, Grund C, Forth L, Pohlmann A, Jeske C, Wintermann M, Beer M, Conraths FJ, Harder T.

Transbound Emerg Dis. 2018 Dec;65(6):1576-1587. doi: 10.1111/tbed.12906. Epub 2018 May 23.

PMID:
29790657
6.

Highly Pathogenic Avian Influenza H5N8 Clade 2.3.4.4b in Germany in 2016/2017.

Globig A, Staubach C, Sauter-Louis C, Dietze K, Homeier-Bachmann T, Probst C, Gethmann J, Depner KR, Grund C, Harder TC, Starick E, Pohlmann A, Höper D, Beer M, Mettenleiter TC, Conraths FJ.

Front Vet Sci. 2018 Jan 24;4:240. doi: 10.3389/fvets.2017.00240. eCollection 2017.

7.

Zoonotic Infection With Pigeon Paramyxovirus Type 1 Linked to Fatal Pneumonia.

Kuiken T, Breitbart M, Beer M, Grund C, Höper D, van den Hoogen B, Kerkhoffs JH, Kroes ACM, Rosario K, van Run P, Schwarz M, Svraka S, Teifke J, Koopmans M.

J Infect Dis. 2018 Aug 24;218(7):1037-1044. doi: 10.1093/infdis/jiy036.

PMID:
29373675
8.
9.

Swarm incursions of reassortants of highly pathogenic avian influenza virus strains H5N8 and H5N5, clade 2.3.4.4b, Germany, winter 2016/17.

Pohlmann A, Starick E, Grund C, Höper D, Strebelow G, Globig A, Staubach C, Conraths FJ, Mettenleiter TC, Harder T, Beer M.

Sci Rep. 2018 Jan 8;8(1):15. doi: 10.1038/s41598-017-16936-8.

10.

Natural Reassortants of Potentially Zoonotic Avian Influenza Viruses H5N1 and H9N2 from Egypt Display Distinct Pathogenic Phenotypes in Experimentally Infected Chickens and Ferrets.

Naguib MM, Ulrich R, Kasbohm E, Eng CLP, Hoffmann D, Grund C, Beer M, Harder TC.

J Virol. 2017 Nov 14;91(23). pii: e01300-17. doi: 10.1128/JVI.01300-17. Print 2017 Dec 1.

11.

Newcastle disease virus mediates pancreatic tumor rejection via NK cell activation and prevents cancer relapse by prompting adaptive immunity.

Schwaiger T, Knittler MR, Grund C, Roemer-Oberdoerfer A, Kapp JF, Lerch MM, Mettenleiter TC, Mayerle J, Blohm U.

Int J Cancer. 2017 Dec 15;141(12):2505-2516. doi: 10.1002/ijc.31026. Epub 2017 Sep 13.

12.

Heterologous post-infection immunity against Egyptian avian influenza virus (AIV) H9N2 modulates the course of subsequent infection by highly pathogenic AIV H5N1, but vaccination immunity does not.

Naguib MM, Grund C, Arafa AS, Abdelwhab EM, Beer M, Harder TC.

J Gen Virol. 2017 Jun;98(6):1169-1173. doi: 10.1099/jgv.0.000767. Epub 2017 Jun 8.

PMID:
28590242
13.

Mirror neuron activation of musicians and non-musicians in response to motion captured piano performances.

Hou J, Rajmohan R, Fang D, Kashfi K, Al-Khalil K, Yang J, Westney W, Grund CM, O'Boyle MW.

Brain Cogn. 2017 Jul;115:47-55. doi: 10.1016/j.bandc.2017.04.001. Epub 2017 May 2.

PMID:
28460215
14.

New real time and conventional RT-PCRs for updated molecular diagnosis of infectious bronchitis virus infection (IBV) in chickens in Egypt associated with frequent co-infections with avian influenza and Newcastle Disease viruses.

Naguib MM, El-Kady MF, Lüschow D, Hassan KE, Arafa AS, El-Zanaty A, Hassan MK, Hafez HM, Grund C, Harder TC.

J Virol Methods. 2017 Jul;245:19-27. doi: 10.1016/j.jviromet.2017.02.018. Epub 2017 Mar 21.

PMID:
28336367
15.

Outbreaks among Wild Birds and Domestic Poultry Caused by Reassorted Influenza A(H5N8) Clade 2.3.4.4 Viruses, Germany, 2016.

Pohlmann A, Starick E, Harder T, Grund C, Höper D, Globig A, Staubach C, Dietze K, Strebelow G, Ulrich RG, Schinköthe J, Teifke JP, Conraths FJ, Mettenleiter TC, Beer M.

Emerg Infect Dis. 2017 Apr;23(4):633-636. doi: 10.3201/eid2304.161949. Epub 2017 Apr 15.

16.

Highly pathogenic avian influenza A(H5N8) outbreaks: protection and management of exposed people in Europe, 2014/15 and 2016.

Adlhoch C, Brown IH, Angelova SG, Bálint Á, Bouwstra R, Buda S, Castrucci MR, Dabrera G, Dán Á, Grund C, Harder T, van der Hoek W, Krisztalovics K, Parry-Ford F, Popescu R, Wallensten A, Zdravkova A, Zohari S, Tsolova S, Penttinen P.

Euro Surveill. 2016 Dec 8;21(49). pii: 30419. doi: 10.2807/1560-7917.ES.2016.21.49.30419.

17.

Progressive glycosylation of the haemagglutinin of avian influenza H5N1 modulates virus replication, virulence and chicken-to-chicken transmission without significant impact on antigenic drift.

Abdelwhab EM, Veits J, Tauscher K, Ziller M, Grund C, Hassan MK, Shaheen M, Harder TC, Teifke J, Stech J, Mettenleiter TC.

J Gen Virol. 2016 Dec;97(12):3193-3204. doi: 10.1099/jgv.0.000648. Epub 2016 Oct 28.

PMID:
27902339
18.

Epidemiological and Molecular Analysis of an Outbreak of Highly Pathogenic Avian Influenza H5N8 clade 2.3.4.4 in a German Zoo: Effective Disease Control with Minimal Culling.

Globig A, Starick E, Homeier T, Pohlmann A, Grund C, Wolf P, Zimmermann A, Wolf C, Heim D, Schlößer H, Zander S, Beer M, Conraths FJ, Harder TC.

Transbound Emerg Dis. 2017 Dec;64(6):1813-1824. doi: 10.1111/tbed.12570. Epub 2016 Nov 15.

PMID:
27860371
19.

A genetically engineered H5 protein expressed in insect cells confers protection against different clades of H5N1 highly pathogenic avian influenza viruses in chickens.

Oliveira Cavalcanti M, Vaughn E, Capua I, Cattoli G, Terregino C, Harder T, Grund C, Vega C, Robles F, Franco J, Darji A, Arafa AS, Mundt E.

Avian Pathol. 2017 Apr;46(2):224-233. doi: 10.1080/03079457.2016.1250866. Epub 2017 Jan 27.

PMID:
27807985
20.

Current Concepts and Controversies in Innate Immunity of Cystic Fibrosis Lung Disease.

Ralhan A, Laval J, Lelis F, Ballbach M, Grund C, Hector A, Hartl D.

J Innate Immun. 2016;8(6):531-540. Epub 2016 Jul 1. Review.

21.

Lack of virological and serological evidence for continued circulation of highly pathogenic avian influenza H5N8 virus in wild birds in the Netherlands, 14 November 2014 to 31 January 2016.

Poen MJ, Verhagen JH, Manvell RJ, Brown I, Bestebroer TM, van der Vliet S, Vuong O, Scheuer RD, van der Jeugd HP, Nolet BA, Kleyheeg E, Müskens GJ, Majoor FA, Grund C, Fouchier RA.

Euro Surveill. 2016 Sep 22;21(38). doi: 10.2807/1560-7917.ES.2016.21.38.30349.

22.

Benefits and Limits of Egg Yolk vs. Serum Samples for Avian Influenza Virus Serosurveillance.

Abdelwhab EM, Grund C, Aly MM, Beer M, Harder TC, Hafez HM.

Avian Dis. 2016 Jun;60(2):496-9. doi: 10.1637/11207-060115-ResNote.

PMID:
27309294
23.

Introduction and enzootic of A/H5N1 in Egypt: Virus evolution, pathogenicity and vaccine efficacy ten years on.

Abdelwhab EM, Hassan MK, Abdel-Moneim AS, Naguib MM, Mostafa A, Hussein ITM, Arafa A, Erfan AM, Kilany WH, Agour MG, El-Kanawati Z, Hussein HA, Selim AA, Kholousy S, El-Naggar H, El-Zoghby EF, Samy A, Iqbal M, Eid A, Ibraheem EM, Pleschka S, Veits J, Nasef SA, Beer M, Mettenleiter TC, Grund C, Ali MM, Harder TC, Hafez HM.

Infect Genet Evol. 2016 Jun;40:80-90. doi: 10.1016/j.meegid.2016.02.023. Epub 2016 Feb 23. Review.

PMID:
26917362
24.

Pathfinding on the Frontier.

Sylvia E, Parks B, Grund C.

Am J Nurs. 2015 Oct;115(10):58-63. doi: 10.1097/01.NAJ.0000471946.51739.b5.

PMID:
26402291
25.

Relationship between Root Apices and the Mandibular Canal: A Cone-beam Computed Tomographic Analysis in a German Population.

Bürklein S, Grund C, Schäfer E.

J Endod. 2015 Oct;41(10):1696-700. doi: 10.1016/j.joen.2015.06.016. Epub 2015 Aug 12.

PMID:
26277053
26.

Complete Genome Sequence of Avian Paramyxovirus Strain APMV-6/red-crested pochard/Balkhash/5842/2013 from Kazakhstan.

Karamendin K, Kydyrmanov A, Seidalina A, Jenckel M, Starick E, Grund C, Asanova S, Khan E, Daulbayeva K, Kasymbekov Y, Zhumatov K, Sayatov M, Beer M, Fereidouni S.

Genome Announc. 2015 Jul 16;3(4). pii: e00158-15. doi: 10.1128/genomeA.00158-15.

27.

Influenza A(H5N8) Virus Similar to Strain in Korea Causing Highly Pathogenic Avian Influenza in Germany.

Harder T, Maurer-Stroh S, Pohlmann A, Starick E, Höreth-Böntgen D, Albrecht K, Pannwitz G, Teifke J, Gunalan V, Lee RT, Sauter-Louis C, Homeier T, Staubach C, Wolf C, Strebelow G, Höper D, Grund C, Conraths FJ, Mettenleiter TC, Beer M.

Emerg Infect Dis. 2015 May;21(5):860-3. doi: 10.3201/eid2105.141897.

28.

Emergence of a novel cluster of influenza A(H5N1) virus clade 2.2.1.2 with putative human health impact in Egypt, 2014/15.

Arafa AS, Naguib MM, Luttermann C, Selim AA, Kilany WH, Hagag N, Samy A, Abdelhalim A, Hassan MK, Abdelwhab EM, Makonnen Y, Dauphin G, Lubroth J, Mettenleiter TC, Beer M, Grund C, Harder TC.

Euro Surveill. 2015 Apr 2;20(13):2-8.

29.

Different regions of the newcastle disease virus fusion protein modulate pathogenicity.

Heiden S, Grund C, Röder A, Granzow H, Kühnel D, Mettenleiter TC, Römer-Oberdörfer A.

PLoS One. 2014 Dec 1;9(12):e113344. doi: 10.1371/journal.pone.0113344. eCollection 2014.

30.

Avian paramyoxvirus-8 immunization reduces viral shedding after homologous APMV-8 challenge but fails to protect against Newcastle disease.

Grund C, Steglich C, Huthmann E, Beer M, Mettenleiter TC, Römer-Oberdörfer A.

Virol J. 2014 Oct 8;11:179. doi: 10.1186/1743-422X-11-179.

31.

Pigeon paramyxovirus type 1 variants with polybasic F protein cleavage site but strikingly different pathogenicity.

Heiden S, Grund C, Höper D, Mettenleiter TC, Römer-Oberdörfer A.

Virus Genes. 2014 Dec;49(3):502-6. doi: 10.1007/s11262-014-1111-7. Epub 2014 Sep 17.

PMID:
25228150
32.

Complementary medicine down-regulates side-effects of hormone therapy in prostate cancer patients.

Beuth J, Van Leendert R, Pempelfort K, Schneider B, Grund C, Engelmann U.

In Vivo. 2014 Sep-Oct;28(5):979-82.

PMID:
25189917
33.

Avian influenza H7N9/13 and H7N7/13: a comparative virulence study in chickens, pigeons, and ferrets.

Kalthoff D, Bogs J, Grund C, Tauscher K, Teifke JP, Starick E, Harder T, Beer M.

J Virol. 2014 Aug;88(16):9153-65. doi: 10.1128/JVI.01241-14. Epub 2014 Jun 4.

34.

Mice with cardiac-restricted overexpression of Myozap are sensitized to biomechanical stress and develop a protein-aggregate-associated cardiomyopathy.

Frank D, Rangrez AY, Poyanmehr R, Seeger TS, Kuhn C, Eden M, Stiebeling K, Bernt A, Grund C, Franke WW, Frey N.

J Mol Cell Cardiol. 2014 Jul;72:196-207. doi: 10.1016/j.yjmcc.2014.03.016. Epub 2014 Mar 31.

PMID:
24698889
35.

Nucleic acid-based detection of influenza A virus subtypes H7 and N9 with a special emphasis on the avian H7N9 virus.

Kalthoff D, Bogs J, Harder T, Grund C, Pohlmann A, Beer M, Hoffmann B.

Euro Surveill. 2014 Mar 13;19(10). pii: 20731.

36.

Chimeric newcastle disease virus protects chickens against avian influenza in the presence of maternally derived NDV immunity.

Steglich C, Grund C, Ramp K, Breithaupt A, Höper D, Keil G, Veits J, Ziller M, Granzow H, Mettenleiter TC, Römer-Oberdörfer A.

PLoS One. 2013 Sep 4;8(9):e72530. doi: 10.1371/journal.pone.0072530. eCollection 2013.

37.

Distinction of subtype-specific antibodies against European porcine influenza viruses by indirect ELISA based on recombinant hemagglutinin protein fragment-1.

Zhao N, Lange E, Kubald S, Grund C, Beer M, Harder TC.

Virol J. 2013 Jul 30;10:246. doi: 10.1186/1743-422X-10-246.

38.

Expanded cocirculation of stable subtypes, emerging lineages, and new sporadic reassortants of porcine influenza viruses in swine populations in Northwest Germany.

Harder TC, Grosse Beilage E, Lange E, Meiners C, Döhring S, Pesch S, Noé T, Grund C, Beer M, Starick E.

J Virol. 2013 Oct;87(19):10460-76. doi: 10.1128/JVI.00381-13. Epub 2013 Jul 3.

39.

Transmembrane protein PERP is a component of tessellate junctions and of other junctional and non-junctional plasma membrane regions in diverse epithelial and epithelium-derived cells.

Franke WW, Heid H, Zimbelmann R, Kuhn C, Winter-Simanowski S, Dörflinger Y, Grund C, Rickelt S.

Cell Tissue Res. 2013 Jul;353(1):99-115. doi: 10.1007/s00441-013-1645-3. Epub 2013 May 21.

40.

Towards a new, ecologically targeted approach to monitoring wild bird populations for avian influenza viruses.

Schoene CU, Staubach C, Grund C, Globig A, Kramer M, Wilking H, Beer M, Conraths FJ, Harder TC; BL Monitoring Group.

Epidemiol Infect. 2013 May;141(5):1050-60. doi: 10.1017/S0950268812001732. Epub 2012 Aug 24.

PMID:
22917447
41.

Consecutive natural influenza a virus infections in sentinel mallards in the evident absence of subtype-specific hemagglutination inhibiting antibodies.

Globig A, Fereidouni SR, Harder TC, Grund C, Beer M, Mettenleiter TC, Starick E.

Transbound Emerg Dis. 2013 Oct;60(5):395-402. doi: 10.1111/j.1865-1682.2012.01357.x. Epub 2012 Jul 22.

PMID:
22816511
42.

Diversifying evolution of highly pathogenic H5N1 avian influenza virus in Egypt from 2006 to 2011.

Abdelwhab EM, Arafa AS, Stech J, Grund C, Stech O, Graeber-Gerberding M, Beer M, Hassan MK, Aly MM, Harder TC, Hafez HM.

Virus Genes. 2012 Aug;45(1):14-23. doi: 10.1007/s11262-012-0758-1. Epub 2012 Jun 5.

PMID:
22669540
43.

Reassortants of pandemic influenza A virus H1N1/2009 and endemic porcine HxN2 viruses emerge in swine populations in Germany.

Starick E, Lange E, Grund C, Grosse Beilage E, Döhring S, Maas A, Noé T, Beer M, Harder TC.

J Gen Virol. 2012 Aug;93(Pt 8):1658-63. doi: 10.1099/vir.0.042648-0. Epub 2012 May 23.

PMID:
22622326
44.

Pathogenicity and immunogenicity of different recombinant Newcastle disease virus clone 30 variants after in ovo vaccination.

Ramp K, Topfstedt E, Wäckerlin R, Höper D, Ziller M, Mettenleiter TC, Grund C, Römer-Oberdörfer A.

Avian Dis. 2012 Mar;56(1):208-17.

PMID:
22545548
45.

E-N-cadherin heterodimers define novel adherens junctions connecting endoderm-derived cells.

Straub BK, Rickelt S, Zimbelmann R, Grund C, Kuhn C, Iken M, Ott M, Schirmacher P, Franke WW.

J Cell Biol. 2011 Nov 28;195(5):873-87. doi: 10.1083/jcb.201106023. Epub 2011 Nov 21.

46.

Coexpression of avian influenza virus H5 and N1 by recombinant Newcastle disease virus and the impact on immune response in chickens.

Ramp K, Veits J, Deckers D, Rudolf M, Grund C, Mettenleiter TC, Römer-Oberdörfer A.

Avian Dis. 2011 Sep;55(3):413-21.

PMID:
22017039
47.

Influence of maternal immunity on vaccine efficacy and susceptibility of one day old chicks against Egyptian highly pathogenic avian influenza H5N1.

Abdelwhab EM, Grund C, Aly MM, Beer M, Harder TC, Hafez HM.

Vet Microbiol. 2012 Feb 24;155(1):13-20. doi: 10.1016/j.vetmic.2011.08.004. Epub 2011 Aug 7.

PMID:
21920677
48.

Multiple dose vaccination with heterologous H5N2 vaccine: immune response and protection against variant clade 2.2.1 highly pathogenic avian influenza H5N1 in broiler breeder chickens.

Abdelwhab EM, Grund C, Aly MM, Beer M, Harder TC, Hafez HM.

Vaccine. 2011 Aug 26;29(37):6219-25. doi: 10.1016/j.vaccine.2011.06.090. Epub 2011 Jul 13.

PMID:
21745517
49.

Analysis of influenza A viruses of subtype H1 from wild birds, turkeys and pigs in Germany reveals interspecies transmission events.

Starick E, Fereidouni SR, Lange E, Grund C, Vahlenkamp T, Beer M, Harder TC.

Influenza Other Respir Viruses. 2011 Jul;5(4):276-84. doi: 10.1111/j.1750-2659.2011.00201.x. Epub 2011 Feb 28.

50.

Highly pathogenic avian influenza virus H5N1 from Egypt escapes vaccine-induced immunity but confers clinical protection against a heterologous clade 2.2.1 Egyptian isolate.

Grund C, Abdelwhab el-SM, Arafa AS, Ziller M, Hassan MK, Aly MM, Hafez HM, Harder TC, Beer M.

Vaccine. 2011 Jul 26;29(33):5567-73. doi: 10.1016/j.vaccine.2011.01.006. Epub 2011 Jan 15.

PMID:
21244859

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