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Targeting NOTCH activation in small cell lung cancer through LSD1 inhibition.

Augert A, Eastwood E, Ibrahim AH, Wu N, Grunblatt E, Basom R, Liggitt D, Eaton KD, Martins R, Poirier JT, Rudin CM, Milletti F, Cheng WY, Mack F, MacPherson D.

Sci Signal. 2019 Feb 5;12(567). pii: eaau2922. doi: 10.1126/scisignal.aau2922.


Cognitive, behavioral and metabolic effects of oral galactose treatment in the transgenic Tg2576 mice.

Babic Perhoc A, Osmanovic Barilar J, Knezovic A, Farkas V, Bagaric R, Svarc A, Grünblatt E, Riederer P, Salkovic-Petrisic M.

Neuropharmacology. 2018 Dec 17;148:50-67. doi: 10.1016/j.neuropharm.2018.12.018. [Epub ahead of print]


Manifesto for a European research network into Problematic Usage of the Internet.

Fineberg NA, Demetrovics Z, Stein DJ, Ioannidis K, Potenza MN, Grünblatt E, Brand M, Billieux J, Carmi L, King DL, Grant JE, Yücel M, Dell'Osso B, Rumpf HJ, Hall N, Hollander E, Goudriaan A, Menchon J, Zohar J, Burkauskas J, Martinotti G, Van Ameringen M, Corazza O, Pallanti S; COST Action Network, Chamberlain SR.

Eur Neuropsychopharmacol. 2018 Nov;28(11):1232-1246. doi: 10.1016/j.euroneuro.2018.08.004. Epub 2018 Oct 10.


Astrocyte- and Microglia-Specific Mitochondrial DNA Deletions Levels in Sporadic Alzheimer's Disease.

Strobel S, Grünblatt E, Heinsen H, Riederer P, Espach T, Meder M, Monoranu CM.

J Alzheimers Dis. 2019;67(1):149-157. doi: 10.3233/JAD-180661.


The involvement of the canonical Wnt-signaling receptor LRP5 and LRP6 gene variants with ADHD and sexual dimorphism: Association study and meta-analysis.

Grünblatt E, Nemoda Z, Werling AM, Roth A, Angyal N, Tarnok Z, Thomsen H, Peters T, Hinney A, Hebebrand J, Lesch KP, Romanos M, Walitza S.

Am J Med Genet B Neuropsychiatr Genet. 2018 Nov 25. doi: 10.1002/ajmg.b.32695. [Epub ahead of print]


Improved Generation of Induced Pluripotent Stem Cells From Hair Derived Keratinocytes - A Tool to Study Neurodevelopmental Disorders as ADHD.

Re S, Dogan AA, Ben-Shachar D, Berger G, Werling AM, Walitza S, Grünblatt E.

Front Cell Neurosci. 2018 Sep 25;12:321. doi: 10.3389/fncel.2018.00321. eCollection 2018.


Neuregulin 1 (NRG1) gene expression predicts functional outcomes in individuals at clinical high-risk for psychosis.

Jagannath V, Gerstenberg M, Walitza S, Franscini M, Heekeren K, Rössler W, Theodoridou A, Grünblatt E.

Psychiatry Res. 2018 Aug;266:143-146. doi: 10.1016/j.psychres.2018.05.025. Epub 2018 May 17.


Glucocorticoid receptor gene variants and lower expression of NR3C1 are associated with cocaine use.

Schote AB, Jäger K, Kroll SL, Vonmoos M, Hulka LM, Preller KH, Meyer J, Grünblatt E, Quednow BB.

Addict Biol. 2018 May 15. doi: 10.1111/adb.12632. [Epub ahead of print]


Augmenting mask-based lithography with direct laser writing to increase resolution and speed.

Lim MP, Guo X, Grunblatt EL, Clifton GM, Gonzalez AN, LaFratta CN.

Opt Express. 2018 Mar 19;26(6):7085-7090. doi: 10.1364/OE.26.007085.


Neurochemical markers as potential indicators of postmortem tissue quality.

Sian-Hülsmann J, Monoranu CM, Grünblatt E, Riederer P.

Handb Clin Neurol. 2018;150:119-127. doi: 10.1016/B978-0-444-63639-3.00009-8. Review.


Methylphenidate enhances neuronal differentiation and reduces proliferation concomitant to activation of Wnt signal transduction pathways.

Grünblatt E, Bartl J, Walitza S.

Transl Psychiatry. 2018 Mar 1;8(1):51. doi: 10.1038/s41398-018-0096-8.

Free PMC Article

Prediction Analysis for Transition to Schizophrenia in Individuals at Clinical High Risk for Psychosis: The Relationship of DAO, DAOA, and NRG1 Variants with Negative Symptoms and Cognitive Deficits.

Jagannath V, Theodoridou A, Gerstenberg M, Franscini M, Heekeren K, Correll CU, Rössler W, Grünblatt E, Walitza S.

Front Psychiatry. 2017 Dec 20;8:292. doi: 10.3389/fpsyt.2017.00292. eCollection 2017.


A pilot investigation on DNA methylation modifications associated with complex posttraumatic symptoms in elderly traumatized in childhood.

Marinova Z, Maercker A, Grünblatt E, Wojdacz TK, Walitza S.

BMC Res Notes. 2017 Dec 19;10(1):752. doi: 10.1186/s13104-017-3082-y.


Differential Alterations in Metabolism and Proteolysis-Related Proteins in Human Parkinson's Disease Substantia Nigra.

Grünblatt E, Ruder J, Monoranu CM, Riederer P, Youdim MB, Mandel SA.

Neurotox Res. 2018 Apr;33(3):560-568. doi: 10.1007/s12640-017-9843-5. Epub 2017 Dec 7.


High resolution chromosomal microarray analysis in paediatric obsessive-compulsive disorder.

Grünblatt E, Oneda B, Ekici AB, Ball J, Geissler J, Uebe S, Romanos M, Rauch A, Walitza S.

BMC Med Genomics. 2017 Nov 28;10(1):68. doi: 10.1186/s12920-017-0299-5.


Combining genetic and epigenetic parameters of the serotonin transporter gene in obsessive-compulsive disorder.

Grünblatt E, Marinova Z, Roth A, Gardini E, Ball J, Geissler J, Wojdacz TK, Romanos M, Walitza S.

J Psychiatr Res. 2018 Jan;96:209-217. doi: 10.1016/j.jpsychires.2017.10.010. Epub 2017 Oct 16.


Integrating evolutionary and regulatory information with a multispecies approach implicates genes and pathways in obsessive-compulsive disorder.

Noh HJ, Tang R, Flannick J, O'Dushlaine C, Swofford R, Howrigan D, Genereux DP, Johnson J, van Grootheest G, Grünblatt E, Andersson E, Djurfeldt DR, Patel PD, Koltookian M, M Hultman C, Pato MT, Pato CN, Rasmussen SA, Jenike MA, Hanna GL, Stewart SE, Knowles JA, Ruhrmann S, Grabe HJ, Wagner M, Rück C, Mathews CA, Walitza S, Cath DC, Feng G, Karlsson EK, Lindblad-Toh K.

Nat Commun. 2017 Oct 17;8(1):774. doi: 10.1038/s41467-017-00831-x.


Explorative results from multistep screening for potential genetic risk loci of Alzheimer's disease in the longitudinal VITA study cohort.

Scholz CJ, Weber H, Jungwirth S, Danielczyk W, Reif A, Tragl KH, Fischer P, Riederer P, Deckert J, Grünblatt E.

J Neural Transm (Vienna). 2018 Jan;125(1):77-87. doi: 10.1007/s00702-017-1796-6. Epub 2017 Oct 12.


A systematic meta-analysis of the association of Neuregulin 1 (NRG1), D-amino acid oxidase (DAO), and DAO activator (DAOA)/G72 polymorphisms with schizophrenia.

Jagannath V, Gerstenberg M, Correll CU, Walitza S, Grünblatt E.

J Neural Transm (Vienna). 2018 Jan;125(1):89-102. doi: 10.1007/s00702-017-1782-z. Epub 2017 Sep 1.


Effects of oxytocin and arginine vasopressin on the proliferation and differentiation of a serotonergic cell line.

Marinova Z, Walitza S, Grünblatt E.

J Neural Transm (Vienna). 2018 Jan;125(1):103-106. doi: 10.1007/s00702-017-1778-8. Epub 2017 Aug 18.


The diabetic brain and cognition.

Riederer P, Korczyn AD, Ali SS, Bajenaru O, Choi MS, Chopp M, Dermanovic-Dobrota V, Grünblatt E, Jellinger KA, Kamal MA, Kamal W, Leszek J, Sheldrick-Michel TM, Mushtaq G, Meglic B, Natovich R, Pirtosek Z, Rakusa M, Salkovic-Petrisic M, Schmidt R, Schmitt A, Sridhar GR, Vécsei L, Wojszel ZB, Yaman H, Zhang ZG, Cukierman-Yaffe T.

J Neural Transm (Vienna). 2017 Nov;124(11):1431-1454. doi: 10.1007/s00702-017-1763-2. Epub 2017 Aug 1. Review.


A Single Dose of LSD Does Not Alter Gene Expression of the Serotonin 2A Receptor Gene (HTR2A) or Early Growth Response Genes (EGR1-3) in Healthy Subjects.

Dolder PC, Grünblatt E, Müller F, Borgwardt SJ, Liechti ME.

Front Pharmacol. 2017 Jun 28;8:423. doi: 10.3389/fphar.2017.00423. eCollection 2017.


The impact of methylphenidate and its enantiomers on dopamine synthesis and metabolism in vitro.

Bartl J, Palazzesi F, Parrinello M, Hommers L, Riederer P, Walitza S, Grünblatt E.

Prog Neuropsychopharmacol Biol Psychiatry. 2017 Oct 3;79(Pt B):281-288. doi: 10.1016/j.pnpbp.2017.07.002. Epub 2017 Jul 8.


Determination of Monoamine Oxidase A and B Activity in Long-Term Treated Patients With Parkinson Disease.

Müller T, Riederer P, Grünblatt E.

Clin Neuropharmacol. 2017 Sep/Oct;40(5):208-211. doi: 10.1097/WNF.0000000000000233.


Emerging role of miRNA in attention deficit hyperactivity disorder: a systematic review.

Srivastav S, Walitza S, Grünblatt E.

Atten Defic Hyperact Disord. 2018 Mar;10(1):49-63. doi: 10.1007/s12402-017-0232-y. Epub 2017 May 10. Review.


Expression of D-Amino Acid Oxidase (DAO/DAAO) and D-Amino Acid Oxidase Activator (DAOA/G72) during Development and Aging in the Human Post-mortem Brain.

Jagannath V, Marinova Z, Monoranu CM, Walitza S, Grünblatt E.

Front Neuroanat. 2017 Apr 6;11:31. doi: 10.3389/fnana.2017.00031. eCollection 2017.


The hallucinogen 2,5-dimethoxy-4-iodoamphetamine hydrochloride activates neurotrophin receptors in a neuronal cell line and promotes neurites extension.

Marinova Z, Walitza S, Grünblatt E.

J Neural Transm (Vienna). 2017 Jun;124(6):749-759. doi: 10.1007/s00702-017-1706-y. Epub 2017 Mar 18.


Simultaneous determination of MAO-A and -B activity following first time intake of an irreversible MAO-B inhibitor in patients with Parkinson's disease.

Müller T, Riederer P, Grünblatt E.

J Neural Transm (Vienna). 2017 Jun;124(6):745-748. doi: 10.1007/s00702-017-1705-z. Epub 2017 Mar 15.


Development of a Novel Markov Chain Model for the Prediction of Head and Neck Squamous Cell Carcinoma Dissemination.

Jung H, Law A, Grunblatt E, Wang LL, Kusano A, Mejino JL Jr, Whipple ME.

AMIA Annu Symp Proc. 2017 Feb 10;2016:1832-1839. eCollection 2016.


DNA methylation profiles of elderly individuals subjected to indentured childhood labor and trauma.

Marinova Z, Maercker A, Küffer A, Robinson MD, Wojdacz TK, Walitza S, Grünblatt E, Burri A.

BMC Med Genet. 2017 Feb 27;18(1):21. doi: 10.1186/s12881-017-0370-2.


Genome sequencing in a case of Niemann-Pick type C.

Dougherty M, Lazar J, Klein JC, Diaz K, Gobillot T, Grunblatt E, Hasle N, Lawrence D, Maurano M, Nelson M, Olson G, Srivatsan S, Shendure J, Keene CD, Bird T, Horwitz MS, Marshall DA.

Cold Spring Harb Mol Case Stud. 2016 Nov;2(6):a001222.


Consensus paper of the WFSBP Task Force on Biological Markers: Criteria for biomarkers and endophenotypes of schizophrenia, part III: Molecular mechanisms.

Schmitt A, Martins-de-Souza D, Akbarian S, Cassoli JS, Ehrenreich H, Fischer A, Fonteh A, Gattaz WF, Gawlik M, Gerlach M, Grünblatt E, Halene T, Hasan A, Hashimoto K, Kim YK, Kirchner SK, Kornhuber J, Kraus TFJ, Malchow B, Nascimento JM, Rossner M, Schwarz M, Steiner J, Talib L, Thibaut F, Riederer P, Falkai P; Members of the WFSBP Task Force on Biological Markers.

World J Biol Psychiatry. 2017 Aug;18(5):330-356. doi: 10.1080/15622975.2016.1224929. Epub 2016 Oct 26. Review.


Biological markers for anxiety disorders, OCD and PTSD: A consensus statement. Part II: Neurochemistry, neurophysiology and neurocognition.

Bandelow B, Baldwin D, Abelli M, Bolea-Alamanac B, Bourin M, Chamberlain SR, Cinosi E, Davies S, Domschke K, Fineberg N, Grünblatt E, Jarema M, Kim YK, Maron E, Masdrakis V, Mikova O, Nutt D, Pallanti S, Pini S, Ströhle A, Thibaut F, Vaghi MM, Won E, Wedekind D, Wichniak A, Woolley J, Zwanzger P, Riederer P.

World J Biol Psychiatry. 2017 Apr;18(3):162-214. doi: 10.1080/15622975.2016.1190867. Epub 2016 Jul 15. Review.


Biological markers for anxiety disorders, OCD and PTSD - a consensus statement. Part I: Neuroimaging and genetics.

Bandelow B, Baldwin D, Abelli M, Altamura C, Dell'Osso B, Domschke K, Fineberg NA, Grünblatt E, Jarema M, Maron E, Nutt D, Pini S, Vaghi MM, Wichniak A, Zai G, Riederer P.

World J Biol Psychiatry. 2016 Aug;17(5):321-65. doi: 10.1080/15622975.2016.1181783. Epub 2016 Jul 12.


The Application of Molecular Diagnostics to Stained Cytology Smears.

Oktay MH, Adler E, Hakima L, Grunblatt E, Pieri E, Seymour A, Khader S, Cajigas A, Suhrland M, Goswami S.

J Mol Diagn. 2016 May;18(3):407-415. doi: 10.1016/j.jmoldx.2016.01.007. Epub 2016 Feb 24.


CNTNAP2 gene in high functioning autism: no association according to family and meta-analysis approaches.

Werling AM, Bobrowski E, Taurines R, Gundelfinger R, Romanos M, Grünblatt E, Walitza S.

J Neural Transm (Vienna). 2016 Mar;123(3):353-63. doi: 10.1007/s00702-015-1458-5. Epub 2015 Nov 11.


α2A -Adrenergic receptor polymorphisms and mRNA expression levels are associated with delay discounting in cocaine users.

Havranek MM, Hulka LM, Tasiudi E, Eisenegger C, Vonmoos M, Preller KH, Mössner R, Baumgartner MR, Seifritz E, Grünblatt E, Quednow BB.

Addict Biol. 2017 Mar;22(2):561-569. doi: 10.1111/adb.12324. Epub 2015 Nov 8.


Characterization of cognitive deficits in spontaneously hypertensive rats, accompanied by brain insulin receptor dysfunction.

Grünblatt E, Bartl J, Iuhos DI, Knezovic A, Trkulja V, Riederer P, Walitza S, Salkovic-Petrisic M.

J Mol Psychiatry. 2015 Jun 4;3(1):6. doi: 10.1186/s40303-015-0012-6. eCollection 2015.


Serotonin Transporter and Tryptophan Hydroxylase Gene Variations Mediate Working Memory Deficits of Cocaine Users.

Havranek MM, Vonmoos M, Müller CP, Büetiger JR, Tasiudi E, Hulka LM, Preller KH, Mössner R, Grünblatt E, Seifritz E, Quednow BB.

Neuropsychopharmacology. 2015 Dec;40(13):2929-37. doi: 10.1038/npp.2015.146. Epub 2015 May 27.


Changes in the expression of genes related to neuroinflammation over the course of sporadic Alzheimer's disease progression: CX3CL1, TREM2, and PPARγ.

Strobel S, Grünblatt E, Riederer P, Heinsen H, Arzberger T, Al-Sarraj S, Troakes C, Ferrer I, Monoranu CM.

J Neural Transm (Vienna). 2015 Jul;122(7):1069-76. doi: 10.1007/s00702-015-1369-5. Epub 2015 Jan 18.


Biological Model Development as an Opportunity to Provide Content Auditing for the Foundational Model of Anatomy Ontology.

Wang LL, Grunblatt E, Jung H, Kalet IJ, Whipple ME.

AMIA Annu Symp Proc. 2015 Nov 5;2015:2111-20. eCollection 2015.


Neurotrophin blood-based gene expression and social cognition analysis in patients with autism spectrum disorder.

Segura M, Pedreño C, Obiols J, Taurines R, Pàmias M, Grünblatt E, Gella A.

Neurogenetics. 2015 Apr;16(2):123-31. doi: 10.1007/s10048-014-0434-9. Epub 2014 Dec 24.


Nine-month follow-up of the insulin receptor signalling cascade in the brain of streptozotocin rat model of sporadic Alzheimer's disease.

Barilar JO, Knezovic A, Grünblatt E, Riederer P, Salkovic-Petrisic M.

J Neural Transm (Vienna). 2015 Apr;122(4):565-76. doi: 10.1007/s00702-014-1323-y. Epub 2014 Dec 12.


Association study in siblings and case-controls of serotonin- and oxytocin-related genes with high functioning autism.

Nyffeler J, Walitza S, Bobrowski E, Gundelfinger R, Grünblatt E.

J Mol Psychiatry. 2014 Jan 24;2(1):1. doi: 10.1186/2049-9256-2-1. eCollection 2014.


Aldehyde dehydrogenase (ALDH) in Alzheimer's and Parkinson's disease.

Grünblatt E, Riederer P.

J Neural Transm (Vienna). 2016 Feb;123(2):83-90. doi: 10.1007/s00702-014-1320-1. Epub 2014 Oct 9. Review.


Cross-disorder genome-wide analyses suggest a complex genetic relationship between Tourette's syndrome and OCD.

Yu D, Mathews CA, Scharf JM, Neale BM, Davis LK, Gamazon ER, Derks EM, Evans P, Edlund CK, Crane J, Fagerness JA, Osiecki L, Gallagher P, Gerber G, Haddad S, Illmann C, McGrath LM, Mayerfeld C, Arepalli S, Barlassina C, Barr CL, Bellodi L, Benarroch F, Berrió GB, Bienvenu OJ, Black DW, Bloch MH, Brentani H, Bruun RD, Budman CL, Camarena B, Campbell DD, Cappi C, Silgado JC, Cavallini MC, Chavira DA, Chouinard S, Cook EH, Cookson MR, Coric V, Cullen B, Cusi D, Delorme R, Denys D, Dion Y, Eapen V, Egberts K, Falkai P, Fernandez T, Fournier E, Garrido H, Geller D, Gilbert DL, Girard SL, Grabe HJ, Grados MA, Greenberg BD, Gross-Tsur V, Grünblatt E, Hardy J, Heiman GA, Hemmings SM, Herrera LD, Hezel DM, Hoekstra PJ, Jankovic J, Kennedy JL, King RA, Konkashbaev AI, Kremeyer B, Kurlan R, Lanzagorta N, Leboyer M, Leckman JF, Lennertz L, Liu C, Lochner C, Lowe TL, Lupoli S, Macciardi F, Maier W, Manunta P, Marconi M, McCracken JT, Mesa Restrepo SC, Moessner R, Moorjani P, Morgan J, Muller H, Murphy DL, Naarden AL, Nurmi E, Ochoa WC, Ophoff RA, Pakstis AJ, Pato MT, Pato CN, Piacentini J, Pittenger C, Pollak Y, Rauch SL, Renner T, Reus VI, Richter MA, Riddle MA, Robertson MM, Romero R, Rosário MC, Rosenberg D, Ruhrmann S, Sabatti C, Salvi E, Sampaio AS, Samuels J, Sandor P, Service SK, Sheppard B, Singer HS, Smit JH, Stein DJ, Strengman E, Tischfield JA, Turiel M, Valencia Duarte AV, Vallada H, Veenstra-VanderWeele J, Walitza S, Wang Y, Weale M, Weiss R, Wendland JR, Westenberg HG, Shugart YY, Hounie AG, Miguel EC, Nicolini H, Wagner M, Ruiz-Linares A, Cath DC, McMahon W, Posthuma D, Oostra BA, Nestadt G, Rouleau GA, Purcell S, Jenike MA, Heutink P, Hanna GL, Conti DV, Arnold PD, Freimer NB, Stewart SE, Knowles JA, Cox NJ, Pauls DL.

Am J Psychiatry. 2015 Jan;172(1):82-93. doi: 10.1176/appi.ajp.2014.13101306. Epub 2014 Oct 31.


Common mechanisms in neurodegeneration and neuroinflammation: a BrainNet Europe gene expression microarray study.

Durrenberger PF, Fernando FS, Kashefi SN, Bonnert TP, Seilhean D, Nait-Oumesmar B, Schmitt A, Gebicke-Haerter PJ, Falkai P, Grünblatt E, Palkovits M, Arzberger T, Kretzschmar H, Dexter DT, Reynolds R.

J Neural Transm (Vienna). 2015 Jul;122(7):1055-68. doi: 10.1007/s00702-014-1293-0. Epub 2014 Aug 13.


Prenatal stress increases the striatal and hippocampal expression of correlating c-FOS and serotonin transporters in murine offspring.

Bielas H, Arck P, Bruenahl CA, Walitza S, Grünblatt E.

Int J Dev Neurosci. 2014 Nov;38:30-5. doi: 10.1016/j.ijdevneu.2014.07.006. Epub 2014 Aug 4.


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