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Items: 34


Selenoprotein T is a novel OST subunit that regulates UPR signaling and hormone secretion.

Hamieh A, Cartier D, Abid H, Calas A, Burel C, Bucharles C, Jehan C, Grumolato L, Landry M, Lerouge P, Anouar Y, Lihrmann I.

EMBO Rep. 2017 Nov;18(11):1935-1946. doi: 10.15252/embr.201643504. Epub 2017 Sep 19.


CRISPR/Cas9 editing of the genome for cancer modeling.

Guernet A, Grumolato L.

Methods. 2017 May 15;121-122:130-137. doi: 10.1016/j.ymeth.2017.03.007. Epub 2017 Mar 10. Review.


Modeling intratumor heterogeneity through CRISPR-barcodes.

Guernet A, Aaronson SA, Anouar Y, Grumolato L.

Mol Cell Oncol. 2016 Sep 6;3(6):e1227894. doi: 10.1080/23723556.2016.1227894. eCollection 2016.


CRISPR-Barcoding for Intratumor Genetic Heterogeneity Modeling and Functional Analysis of Oncogenic Driver Mutations.

Guernet A, Mungamuri SK, Cartier D, Sachidanandam R, Jayaprakash A, Adriouch S, Vezain M, Charbonnier F, Rohkin G, Coutant S, Yao S, Ainani H, Alexandre D, Tournier I, Boyer O, Aaronson SA, Anouar Y, Grumolato L.

Mol Cell. 2016 Aug 4;63(3):526-38. doi: 10.1016/j.molcel.2016.06.017. Epub 2016 Jul 21.


ROR1 contributes to melanoma cell growth and migration by regulating N-cadherin expression via the PI3K/Akt pathway.

Fernández NB, Lorenzo D, Picco ME, Barbero G, Dergan-Dylon LS, Marks MP, García-Rivello H, Gimenez L, Labovsky V, Grumolato L, Lopez-Bergami P.

Mol Carcinog. 2016 Nov;55(11):1772-1785. doi: 10.1002/mc.22426. Epub 2015 Oct 28.


Chromatin modifications sequentially enhance ErbB2 expression in ErbB2-positive breast cancers.

Mungamuri SK, Murk W, Grumolato L, Bernstein E, Aaronson SA.

Cell Rep. 2013 Oct 31;5(2):302-13. doi: 10.1016/j.celrep.2013.09.009. Epub 2013 Oct 10.


β-Catenin-independent activation of TCF1/LEF1 in human hematopoietic tumor cells through interaction with ATF2 transcription factors.

Grumolato L, Liu G, Haremaki T, Mungamuri SK, Mong P, Akiri G, Lopez-Bergami P, Arita A, Anouar Y, Mlodzik M, Ronai ZA, Brody J, Weinstein DC, Aaronson SA.

PLoS Genet. 2013;9(8):e1003603. doi: 10.1371/journal.pgen.1003603. Epub 2013 Aug 15.


Wnk kinases are positive regulators of canonical Wnt/β-catenin signalling.

Serysheva E, Berhane H, Grumolato L, Demir K, Balmer S, Bodak M, Boutros M, Aaronson S, Mlodzik M, Jenny A.

EMBO Rep. 2013 Aug;14(8):718-25. doi: 10.1038/embor.2013.88. Epub 2013 Jun 25. Erratum in: EMBO Rep. 2013 Sep;14(9):845.


High-frequency canonical Wnt activation in multiple sarcoma subtypes drives proliferation through a TCF/β-catenin target gene, CDC25A.

Vijayakumar S, Liu G, Rus IA, Yao S, Chen Y, Akiri G, Grumolato L, Aaronson SA.

Cancer Cell. 2011 May 17;19(5):601-12. doi: 10.1016/j.ccr.2011.03.010.


Maternal perinatal undernutrition has long-term consequences on morphology, function and gene expression of the adrenal medulla in the adult male rat.

Laborie C, Molendi-Coste O, Breton C, Montel V, Vandenbulcke F, Grumolato L, Anouar Y, Vieau D.

J Neuroendocrinol. 2011 Aug;23(8):711-24. doi: 10.1111/j.1365-2826.2011.02159.x.


A new piece to the unsolved planar cell polarity puzzle.

Grumolato L, Weber U, Mlodzik M.

Dev Cell. 2011 Feb 15;20(2):146-7. doi: 10.1016/j.devcel.2011.01.013.


Canonical and noncanonical Wnts use a common mechanism to activate completely unrelated coreceptors.

Grumolato L, Liu G, Mong P, Mudbhary R, Biswas R, Arroyave R, Vijayakumar S, Economides AN, Aaronson SA.

Genes Dev. 2010 Nov 15;24(22):2517-30. doi: 10.1101/gad.1957710.


Diverse mechanisms of Wnt activation and effects of pathway inhibition on proliferation of human gastric carcinoma cells.

Asciutti S, Akiri G, Grumolato L, Vijayakumar S, Aaronson SA.

Oncogene. 2011 Feb 24;30(8):956-66. doi: 10.1038/onc.2010.475. Epub 2010 Nov 1.


Abelson family kinases regulate Frizzled planar cell polarity signaling via Dsh phosphorylation.

Singh J, Yanfeng WA, Grumolato L, Aaronson SA, Mlodzik M.

Genes Dev. 2010 Oct 1;24(19):2157-68. doi: 10.1101/gad.1961010. Epub 2010 Sep 13.


Canonical Wnts function as potent regulators of osteogenesis by human mesenchymal stem cells.

Liu G, Vijayakumar S, Grumolato L, Arroyave R, Qiao H, Akiri G, Aaronson SA.

J Cell Biol. 2009 Apr 6;185(1):67-75. doi: 10.1083/jcb.200810137.


Selenoprotein T is a PACAP-regulated gene involved in intracellular Ca2+ mobilization and neuroendocrine secretion.

Grumolato L, Ghzili H, Montero-Hadjadje M, Gasman S, Lesage J, Tanguy Y, Galas L, Ait-Ali D, Leprince J, Guérineau NC, Elkahloun AG, Fournier A, Vieau D, Vaudry H, Anouar Y.

FASEB J. 2008 Jun;22(6):1756-68. doi: 10.1096/fj.06-075820. Epub 2008 Jan 15.


Role of PACAP in the physiology and pathology of the sympathoadrenal system.

Ghzili H, Grumolato L, Thouënnon E, Tanguy Y, Turquier V, Vaudry H, Anouar Y.

Front Neuroendocrinol. 2008 Jan;29(1):128-41. Epub 2007 Oct 22. Review.


Identification of potential gene markers and insights into the pathophysiology of pheochromocytoma malignancy.

Thouënnon E, Elkahloun AG, Guillemot J, Gimenez-Roqueplo AP, Bertherat J, Pierre A, Ghzili H, Grumolato L, Muresan M, Klein M, Lefebvre H, Ouafik L, Vaudry H, Plouin PF, Yon L, Anouar Y.

J Clin Endocrinol Metab. 2007 Dec;92(12):4865-72. Epub 2007 Sep 18.


Possible implication of the transcriptional regulator Id3 in PACAP-induced pro-survival signaling during PC12 cell differentiation.

Ghzili H, Grumolato L, Thouënnon E, Vaudry H, Anouar Y.

Regul Pept. 2006 Nov 15;137(1-2):89-94. Epub 2006 Aug 22.


Maternal perinatal undernutrition alters neuronal and neuroendocrine differentiation in the rat adrenal medulla at weaning.

Molendi-Coste O, Grumolato L, Laborie C, Lesage J, Maubert E, Ghzili H, Vaudry H, Anouar Y, Breton C, Vieau D.

Endocrinology. 2006 Jun;147(6):3050-9. Epub 2006 Feb 23.


Circulating EM66 is a highly sensitive marker for the diagnosis and follow-up of pheochromocytoma.

Guillemot J, Anouar Y, Montero-Hadjadje M, Grouzmann E, Grumolato L, Roshmaninho-Salgado J, Turquier V, Duparc C, Lefebvre H, Plouin PF, Klein M, Muresan M, Chow BK, Vaudry H, Yon L.

Int J Cancer. 2006 Apr 15;118(8):2003-12.


Identification of the secretogranin II-derived peptide EM66 in pheochromocytomas as a potential marker for discriminating benign versus malignant tumors.

Yon L, Guillemot J, Montero-Hadjadje M, Grumolato L, Leprince J, Lefebvre H, Contesse V, Plouin PF, Vaudry H, Anouar Y.

J Clin Endocrinol Metab. 2003 Jun;88(6):2579-85.


Microarray and suppression subtractive hybridization analyses of gene expression in pheochromocytoma cells reveal pleiotropic effects of pituitary adenylate cyclase-activating polypeptide on cell proliferation, survival, and adhesion.

Grumolato L, Elkahloun AG, Ghzili H, Alexandre D, Coulouarn C, Yon L, Salier JP, Eiden LE, Fournier A, Vaudry H, Anouar Y.

Endocrinology. 2003 Jun;144(6):2368-79.


PACAP and NGF regulate common and distinct traits of the sympathoadrenal lineage: effects on electrical properties, gene markers and transcription factors in differentiating PC12 cells.

Grumolato L, Louiset E, Alexandre D, Aït-Ali D, Turquier V, Fournier A, Fasolo A, Vaudry H, Anouar Y.

Eur J Neurosci. 2003 Jan;17(1):71-82.


Pituitary adenylate cyclase--activating polypeptide stimulates secretoneurin release and secretogranin II gene transcription in bovine adrenochromaffin cells.

Turquier V, Yon L, Grumolato L, Alexandre D, Fournier A, Vaudry H, Anouar Y.

Ann N Y Acad Sci. 2002 Oct;971:471-3. No abstract available.


Pituitary adenylate cyclase-activating polypeptide regulates neuroendocrine markers and transcription factors in differentiating pheochromocytoma cells.

Grumolato L, Alexandre D, Turquier V, Ait-Ali D, Fournier A, Vaudry H, Anouar Y.

Ann N Y Acad Sci. 2002 Oct;971:467-70. No abstract available.


Proinflammatory cytokines TNF-alpha and IL-1alpha stimulate neuropeptide gene expression in adrenochromaffin cells.

Turquier V, Vaudry H, Yon L, Hsu CM, Ait-Ali D, Grumolato L, Eiden LE, Anouar Y.

Ann N Y Acad Sci. 2002 Oct;971:45-8. No abstract available.


Novel splice variants of type I pituitary adenylate cyclase-activating polypeptide receptor in frog exhibit altered adenylate cyclase stimulation and differential relative abundance.

Alexandre D, Vaudry H, Grumolato L, Turquier V, Fournier A, Jégou S, Anouar Y.

Endocrinology. 2002 Jul;143(7):2680-92.


Molecular characterization of frog chromogranin B reveals conservation of selective sequences encoding potential novel regulatory peptides.

Aït-Ali D, Turquier V, Alexandre D, Grumolato L, Jégou S, Vaudry H, Anouar Y.

FEBS Lett. 2002 Jan 30;511(1-3):127-32.


Pharmacological and molecular characterization of 5-hydroxytryptamine(7) receptors in the rat adrenal gland.

Contesse V, Lenglet S, Grumolato L, Anouar Y, Lihrmann I, Lefebvre H, Delarue C, Vaudry H.

Mol Pharmacol. 1999 Sep;56(3):552-61.


Pharmacological profile of serotonergic receptors in the adrenal gland.

Delarue C, Contesse V, Lefebvre H, Lenglet S, Grumolato L, Kuhn JM, Vaudry H.

Endocr Res. 1998 Aug-Nov;24(3-4):687-94.


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