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Items: 23

1.

In silico and in vitro immunogenicity assessment of B-domain-modified recombinant factor VIII molecules.

Bartholdy C, Reedtz-Runge SL, Wang J, Hjerrild Zeuthen L, Gruhler A, Gudme CN, Lamberth K.

Haemophilia. 2018 Sep;24(5):e354-e362. doi: 10.1111/hae.13555. Epub 2018 Jul 19.

PMID:
30024643
2.

Collagen induces maturation of human monocyte-derived dendritic cells by signaling through osteoclast-associated receptor.

Schultz HS, Nitze LM, Zeuthen LH, Keller P, Gruhler A, Pass J, Chen J, Guo L, Fleetwood AJ, Hamilton JA, Berchtold MW, Panina S.

J Immunol. 2015 Apr 1;194(7):3169-79. doi: 10.4049/jimmunol.1402800. Epub 2015 Feb 27.

3.

Hemostatic effect of a monoclonal antibody mAb 2021 blocking the interaction between FXa and TFPI in a rabbit hemophilia model.

Hilden I, Lauritzen B, Sørensen BB, Clausen JT, Jespersgaard C, Krogh BO, Bowler AN, Breinholt J, Gruhler A, Svensson LA, Petersen HH, Petersen LC, Balling KW, Hansen L, Hermit MB, Egebjerg T, Friederichsen B, Ezban M, Bjørn SE.

Blood. 2012 Jun 14;119(24):5871-8. doi: 10.1182/blood-2012-01-401620. Epub 2012 May 4.

PMID:
22563084
4.

Rat liver sinusoidal endothelial cells (LSECs) express functional low density lipoprotein receptor-related protein-1 (LRP-1).

Øie CI, Appa RS, Hilden I, Petersen HH, Gruhler A, Smedsrød B, Hansen JB.

J Hepatol. 2011 Dec;55(6):1346-52. doi: 10.1016/j.jhep.2011.03.013. Epub 2011 Apr 13.

PMID:
21703209
5.

A comparative integrated transcript analysis and functional characterization of differential mechanisms for induction of liver hypertrophy in the rat.

Boitier E, Amberg A, Barbié V, Blichenberg A, Brandenburg A, Gmuender H, Gruhler A, McCarthy D, Meyer K, Riefke B, Raschke M, Schoonen W, Sieber M, Suter L, Thomas CE, Sajot N.

Toxicol Appl Pharmacol. 2011 Apr 15;252(2):85-96. doi: 10.1016/j.taap.2011.01.021. Epub 2011 Feb 26.

PMID:
21315101
6.

Protocols of two-dimensional difference gel electrophoresis to investigate mechanisms of toxicity.

Com E, Gruhler A, Courcol M, Gautier JC.

Methods Mol Biol. 2011;691:187-203. doi: 10.1007/978-1-60761-849-2_11.

PMID:
20972754
7.

The enhanced value of combining conventional and "omics" analyses in early assessment of drug-induced hepatobiliary injury.

Ellinger-Ziegelbauer H, Adler M, Amberg A, Brandenburg A, Callanan JJ, Connor S, Fountoulakis M, Gmuender H, Gruhler A, Hewitt P, Hodson M, Matheis KA, McCarthy D, Raschke M, Riefke B, Schmitt CS, Sieber M, Sposny A, Suter L, Sweatman B, Mally A.

Toxicol Appl Pharmacol. 2011 Apr 15;252(2):97-111. doi: 10.1016/j.taap.2010.09.022. Epub 2010 Oct 1.

PMID:
20888850
8.

The sphingolipid long-chain base-Pkh1/2-Ypk1/2 signaling pathway regulates eisosome assembly and turnover.

Luo G, Gruhler A, Liu Y, Jensen ON, Dickson RC.

J Biol Chem. 2008 Apr 18;283(16):10433-44. doi: 10.1074/jbc.M709972200. Epub 2008 Feb 22.

9.

Quantitation with virtual expert mass spectrometrist.

Gruhler A, Matthiesen R.

Methods Mol Biol. 2007;367:139-52.

PMID:
17185774
10.

Stable isotope labeling of Arabidopsis thaliana cells and quantitative proteomics by mass spectrometry.

Gruhler A, Schulze WX, Matthiesen R, Mann M, Jensen ON.

Mol Cell Proteomics. 2005 Nov;4(11):1697-709. Epub 2005 Aug 8.

11.

Quantitative phosphoproteomics applied to the yeast pheromone signaling pathway.

Gruhler A, Olsen JV, Mohammed S, Mortensen P, Faergeman NJ, Mann M, Jensen ON.

Mol Cell Proteomics. 2005 Mar;4(3):310-27. Epub 2005 Jan 22.

12.

Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry.

Ho Y, Gruhler A, Heilbut A, Bader GD, Moore L, Adams SL, Millar A, Taylor P, Bennett K, Boutilier K, Yang L, Wolting C, Donaldson I, Schandorff S, Shewnarane J, Vo M, Taggart J, Goudreault M, Muskat B, Alfarano C, Dewar D, Lin Z, Michalickova K, Willems AR, Sassi H, Nielsen PA, Rasmussen KJ, Andersen JR, Johansen LE, Hansen LH, Jespersen H, Podtelejnikov A, Nielsen E, Crawford J, Poulsen V, Sørensen BD, Matthiesen J, Hendrickson RC, Gleeson F, Pawson T, Moran MF, Durocher D, Mann M, Hogue CW, Figeys D, Tyers M.

Nature. 2002 Jan 10;415(6868):180-3.

PMID:
11805837
13.

Characterization of human muscle type cofilin (CFL2) in normal and regenerating muscle.

Thirion C, Stucka R, Mendel B, Gruhler A, Jaksch M, Nowak KJ, Binz N, Laing NG, Lochmüller H.

Eur J Biochem. 2001 Jun;268(12):3473-82.

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A comparison of viral immune escape strategies targeting the MHC class I assembly pathway.

Früh K, Gruhler A, Krishna RM, Schoenhals GJ.

Immunol Rev. 1999 Apr;168:157-66. Review.

PMID:
10399072
17.

N-terminal hydrophobic sorting signals of preproteins confer mitochondrial hsp70 independence for import into mitochondria.

Gruhler A, Arnold I, Seytter T, Guiard B, Schwarz E, Neupert W, Stuart RA.

J Biol Chem. 1997 Jul 11;272(28):17410-5.

18.

The ER-luminal domain of the HCMV glycoprotein US6 inhibits peptide translocation by TAP.

Ahn K, Gruhler A, Galocha B, Jones TR, Wiertz EJ, Ploegh HL, Peterson PA, Yang Y, Früh K.

Immunity. 1997 May;6(5):613-21.

19.

Sorting of cytochrome b2 to the intermembrane space of mitochondria. Kinetic analysis of intermediates demonstrates passage through the matrix.

Ono H, Gruhler A, Stuart RA, Guiard B, Schwarz E, Neupert W.

J Biol Chem. 1995 Jul 14;270(28):16932-8.

20.

A novel intermediate on the import pathway of cytochrome b2 into mitochondria: evidence for conservative sorting.

Gruhler A, Ono H, Guiard B, Neupert W, Stuart RA.

EMBO J. 1995 Apr 3;14(7):1349-59.

21.

The requirement of matrix ATP for the import of precursor proteins into the mitochondrial matrix and intermembrane space.

Stuart RA, Gruhler A, van der Klei I, Guiard B, Koll H, Neupert W.

Eur J Biochem. 1994 Feb 15;220(1):9-18.

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