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Items: 1 to 50 of 55

1.

Theoretical study of the ligand-CYP2B4 complexes: effect of structure on binding free energies and heme spin state.

Harris DL, Park JY, Gruenke L, Waskell L.

Proteins. 2004 Jun 1;55(4):895-914. Erratum in: Proteins. 2004 Nov 15;57(3):643.

PMID:
15146488
2.

Determination of the rate of reduction of oxyferrous cytochrome P450 2B4 by 5-deazariboflavin adenine dinucleotide T491V cytochrome P450 reductase.

Zhang H, Gruenke L, Arscott D, Shen A, Kasper C, Harris DL, Glavanovich M, Johnson R, Waskell L.

Biochemistry. 2003 Oct 14;42(40):11594-603.

PMID:
14529269
3.

Preparation and characterization of a 5'-deazaFAD T491V NADPH-cytochrome P450 reductase.

Zhang H, Gruenke L, Saribas AS, Im SC, Shen AL, Kasper CB, Waskell L.

Biochemistry. 2003 Jun 10;42(22):6804-13.

PMID:
12779335
4.

Overexpression and purification of the membrane-bound cytochrome P450 2B4.

Saribas AS, Gruenke L, Waskell L.

Protein Expr Purif. 2001 Mar;21(2):303-9.

PMID:
11237692
5.

Do the pharmacokinetics of vecuronium change during prolonged administration in critically ill patients?

Segredo V, Caldwell JE, Wright PM, Sharma ML, Gruenke LD, Miller RD.

Br J Anaesth. 1998 Jun;80(6):715-9.

6.

Identification of the binding site on cytochrome P450 2B4 for cytochrome b5 and cytochrome P450 reductase.

Bridges A, Gruenke L, Chang YT, Vakser IA, Loew G, Waskell L.

J Biol Chem. 1998 Jul 3;273(27):17036-49.

7.

Resonance Raman spectral properties and stability of manganese protoporphyrin IX cytochrome b5.

Gruenke LD, Sun J, Loehr TM, Waskell L.

Biochemistry. 1997 Jun 10;36(23):7114-25.

PMID:
9188711
8.
9.

The pharmacokinetics and neuromuscular effects of rocuronium bromide in patients with liver disease.

Magorian T, Wood P, Caldwell J, Fisher D, Segredo V, Szenohradszky J, Sharma M, Gruenke L, Miller R.

Anesth Analg. 1995 Apr;80(4):754-9.

PMID:
7893030
10.

Edrophonium increases mivacurium concentrations during constant mivacurium infusion, and large doses minimally antagonize paralysis.

Hart PS, Wright PM, Brown R, Lau M, Sharma ML, Miller RD, Gruenke L, Fisher DM.

Anesthesiology. 1995 Apr;82(4):912-8.

PMID:
7717563
11.

The magnitude and time course of vecuronium potentiation by desflurane versus isoflurane.

Wright PM, Hart P, Lau M, Brown R, Sharma ML, Gruenke L, Fisher DM.

Anesthesiology. 1995 Feb;82(2):404-11.

PMID:
7856899
12.

The pharmacodynamics and pharmacokinetics of the metabolite 3-desacetylvecuronium (ORG 7268) and its parent compound, vecuronium, in human volunteers.

Caldwell JE, Szenohradszky J, Segredo V, Wright PM, McLoughlin C, Sharma ML, Gruenke LD, Fisher DM, Miller RD.

J Pharmacol Exp Ther. 1994 Sep;270(3):1216-22.

PMID:
7932174
13.

Cumulative characteristics of atracurium and vecuronium. A simultaneous clinical and pharmacokinetic study.

Wright PM, Hart P, Lau M, Sharma ML, Gruenke L, Fisher DM.

Anesthesiology. 1994 Jul;81(1):59-68; discussion 27A.

PMID:
7913801
14.

Interaction of rocuronium (ORG 9426) and phenytoin in a patient undergoing cadaver renal transplantation: a possible pharmacokinetic mechanism?

Szenohradszky J, Caldwell JE, Sharma ML, Gruenke LD, Miller RD.

Anesthesiology. 1994 May;80(5):1167-70. No abstract available.

PMID:
8017655
15.

Mild intraoperative hypothermia does not change the pharmacodynamics (concentration-effect relationship) of vecuronium in humans.

Heier T, Caldwell JE, Sharma ML, Gruenke LD, Miller RD.

Anesth Analg. 1994 May;78(5):973-7.

PMID:
7909212
16.

Pharmacokinetics of rocuronium bromide (ORG 9426) in patients with normal renal function or patients undergoing cadaver renal transplantation.

Szenohradszky J, Fisher DM, Segredo V, Caldwell JE, Bragg P, Sharma ML, Gruenke LD, Miller RD.

Anesthesiology. 1992 Nov;77(5):899-904.

PMID:
1443743
17.

Persistent paralysis in critically ill patients after long-term administration of vecuronium.

Segredo V, Caldwell JE, Matthay MA, Sharma ML, Gruenke LD, Miller RD.

N Engl J Med. 1992 Aug 20;327(8):524-8.

18.

Fluoride metabolites after prolonged exposure of volunteers and patients to desflurane.

Sutton TS, Koblin DD, Gruenke LD, Weiskopf RB, Rampil IJ, Waskell L, Eger EI 2nd.

Anesth Analg. 1991 Aug;73(2):180-5.

PMID:
1854033
19.

Pharmacokinetics, neuromuscular effects, and biodisposition of 3-desacetylvecuronium (Org 7268) in cats.

Segredo V, Shin YS, Sharma ML, Gruenke LD, Caldwell JE, Khuenl-Brady KS, Agoston S, Miller RD.

Anesthesiology. 1991 Jun;74(6):1052-9.

PMID:
1675040
20.

Prolonged neuromuscular blockade after long-term administration of vecuronium in two critically ill patients.

Segredo V, Matthay MA, Sharma ML, Gruenke LD, Caldwell JE, Miller RD.

Anesthesiology. 1990 Mar;72(3):566-70. No abstract available.

PMID:
1968730
21.

Factors associated with obtaining nipple aspirate fluid: analysis of 1428 women and literature review.

Wrensch MR, Petrakis NL, Gruenke LD, Ernster VL, Miike R, King EB, Hauck WW.

Breast Cancer Res Treat. 1990 Jan;15(1):39-51. Review.

PMID:
2183892
22.

Metabolism of isoflurane in patients receiving isoniazid.

Gauntlett IS, Koblin DD, Fahey MR, Konopka K, Gruenke LD, Waskell L, Eger EI 2nd.

Anesth Analg. 1989 Aug;69(2):245-9. No abstract available.

PMID:
2764294
23.

Synthesis and hydrolytic behavior of the sulfate conjugate of 2'-hydroxy-3,4,4'-trichlorocarbanilide.

Craig JC, Gruenke LD, North-Root H, Corbin NC.

Drug Metab Dispos. 1989 May-Jun;17(3):345-7. No abstract available.

PMID:
2568919
24.

Breast fluid cholesterol and cholesterol beta-epoxide concentrations in women with benign breast disease.

Wrensch MR, Petrakis NL, Gruenke LD, Miike R, Ernster VL, King EB, Hauck WW, Craig JC, Goodson WH 3rd.

Cancer Res. 1989 Apr 15;49(8):2168-74. Erratum in: Cancer Res 1989 Jul 1;49(13):3710.

26.
27.

Breast fluid cholesterol and cholesterol epoxides: relationship to breast cancer risk factors and other characteristics.

Gruenke LD, Wrensch MR, Petrakis NL, Miike R, Ernster VL, Craig JC.

Cancer Res. 1987 Oct 15;47(20):5483-7.

28.
29.

A selected ion monitoring GC/MS assay for 3,4,4'-trichlorocarbanilide and its metabolites in biological fluids.

Gruenke LD, Craig JC, Wester RC, Maibach HI, North-Root H, Corbin NC.

J Anal Toxicol. 1987 Mar-Apr;11(2):75-80.

PMID:
3573729
30.

Quantitative analysis of benzene by selected ion monitoring/gas chromatography/mass spectrometry.

Gruenke LD, Craig JC, Wester RC, Maibach HI.

J Anal Toxicol. 1986 Nov-Dec;10(6):225-32.

PMID:
3807320
31.

Quantitative estimation of quaternary ammonium neuromuscular blocking agents in serum by direct insertion probe chemical ionization mass spectrometry.

Castagnoli KP, Shinohara Y, Furuta T, Nguyen TL, Gruenke LD, Miller RD, Castagnoli N Jr.

Biomed Environ Mass Spectrom. 1986 Jul;13(7):327-32.

PMID:
2874852
32.

Benzene levels in ambient air and breath of smokers and nonsmokers in urban and pristine environments.

Wester RC, Maibach HI, Gruenke LD, Craig JC.

J Toxicol Environ Health. 1986;18(4):567-73.

PMID:
3735457
33.

Determination of chlorpromazine and its major metabolites by gas chromatography/mass spectrometry: application to biological fluids.

Gruenke LD, Craig JC, Klein FD, Nguyen TL, Hitzemann BA, Holaday JW, Loh HH, Braff L, Fischer A, Glick ID, et al.

Biomed Mass Spectrom. 1985 Dec;12(12):707-13.

PMID:
2936401
34.

Metabolic fate of extracted glucose in normal human myocardium.

Wisneski JA, Gertz EW, Neese RA, Gruenke LD, Morris DL, Craig JC.

J Clin Invest. 1985 Nov;76(5):1819-27.

35.

Placental transfer of ephedrine does not affect neonatal outcome.

Hughes SC, Ward MG, Levinson G, Shnider SM, Wright RG, Gruenke LD, Craig JC.

Anesthesiology. 1985 Aug;63(2):217-9. No abstract available.

PMID:
4025872
36.
37.

Stable isotope dilution analysis of orotic acid and uracil in amniotic fluid.

Jakobs C, Sweetman L, Nyhan WL, Gruenke L, Craig JC, Wadman SK.

Clin Chim Acta. 1984 Nov 15;143(2):123-33.

PMID:
6391739
38.

A stable isotope technique for investigating lactate metabolism in humans.

Neese RA, Gertz EW, Wisneski JA, Gruenke LD, Craig JC.

Biomed Mass Spectrom. 1983 Aug;10(8):458-62.

PMID:
6616022
39.

Chlorpromazine metabolism in extracts of liver and small intestine from guinea pig and from man.

Hartmann F, Gruenke LD, Craig JC, Bissell DM.

Drug Metab Dispos. 1983 May-Jun;11(3):244-8.

PMID:
6135583
40.

Simultaneous analysis of imipramine and its metabolite desipramine in biological fluids.

Craig JC, Gruenke LD, Nguyen TL.

J Chromatogr. 1982 Apr 30;239:81-6.

PMID:
7096509
41.

Cholesterol and cholesterol epoxides in nipple aspirates of human breast fluid.

Petrakis NL, Gruenke LD, Craig JC.

Cancer Res. 1981 Jun;41(6):2563-5.

42.

An improved selected ion recording system for precise isotope ratio determination.

Gruenke LD, Craig JC, Bier DM.

Biomed Mass Spectrom. 1980 Sep;7(9):381-4.

PMID:
7008860
43.

C-Glucuronidation of the acetylenic moiety of ethchlorvynol in the rabbit.

Abolin CR, Tozer TN, Craig JC, Gruenke LD.

Science. 1980 Aug 8;209(4457):703-4.

PMID:
7394528
44.

The determination of nicotine in biological fluids at picogram levels by selected ion recording.

Gruenke LD, Beelen TC, Craig JC, Petrakis NL.

Anal Biochem. 1979 Apr 15;94(2):411-6. No abstract available.

PMID:
464312
45.

Metabolic oxidation of nicotine to chemically reactive intermediates.

Nguyen TL, Gruenke LD, Castagnoli N Jr.

J Med Chem. 1979 Mar;22(3):259-63.

PMID:
423207
46.

Nicotine in breast fluid of nonlactating women.

Petrakis NL, Gruenke LD, Beelen TC, Castagnoli N Jr, Craig JC.

Science. 1978 Jan 20;199(4326):303-5.

PMID:
619458
47.

Measurement of "true" glucose production rates in infancy and childhood with 6,6-dideuteroglucose.

Bier DM, Leake RD, Haymond MW, Arnold KJ, Gruenke LD, Sperling MA, Kipnis DM.

Diabetes. 1977 Nov;26(11):1016-23.

PMID:
913891
48.

Specific lysine labeling by 18OH- during alkaline cleavage of the alpha-1-antitrypsin-trypsin complex.

Cohen AB, Gruenke LD, Craig JC, Geczy D.

Proc Natl Acad Sci U S A. 1977 Oct;74(10):4311-4.

49.

Metabolic N-demethylation of nicotine. Trapping of a reactive iminium species with cyanide ion.

Nguyen TL, Gruenke LD, Castagnoli N Jr.

J Med Chem. 1976 Sep;19(9):1168-9. No abstract available.

PMID:
978682
50.

A contribution to psychoactive drug measurement techniques.

Craig JC, Gruenke LD.

Psychopharmacol Bull. 1975 Oct;11(4):25-7. No abstract available.

PMID:
1197590

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