Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 64

1.

Identification and characterization of OmpT-like proteases in uropathogenic Escherichia coli clinical isolates.

Desloges I, Taylor JA, Leclerc JM, Brannon JR, Portt A, Spencer JD, Dewar K, Marczynski GT, Manges A, Gruenheid S, Le Moual H, Thomassin JL.

Microbiologyopen. 2019 Nov;8(11):e915. doi: 10.1002/mbo3.915. Epub 2019 Sep 8.

2.

Culture-Dependent Bioprospecting of Bacterial Isolates From the Canadian High Arctic Displaying Antibacterial Activity.

Marcolefas E, Leung T, Okshevsky M, McKay G, Hignett E, Hamel J, Aguirre G, Blenner-Hassett O, Boyle B, Lévesque RC, Nguyen D, Gruenheid S, Whyte L.

Front Microbiol. 2019 Aug 9;10:1836. doi: 10.3389/fmicb.2019.01836. eCollection 2019.

3.

Intestinal infection triggers Parkinson's disease-like symptoms in Pink1-/- mice.

Matheoud D, Cannon T, Voisin A, Penttinen AM, Ramet L, Fahmy AM, Ducrot C, Laplante A, Bourque MJ, Zhu L, Cayrol R, Le Campion A, McBride HM, Gruenheid S, Trudeau LE, Desjardins M.

Nature. 2019 Jul;571(7766):565-569. doi: 10.1038/s41586-019-1405-y. Epub 2019 Jul 17.

PMID:
31316206
4.

PmrC (EptA) and CptA Negatively Affect Outer Membrane Vesicle Production in Citrobacter rodentium.

Sinha A, Nyongesa S, Viau C, Gruenheid S, Veyrier FJ, Le Moual H.

J Bacteriol. 2019 Mar 13;201(7). pii: e00454-18. doi: 10.1128/JB.00454-18. Print 2019 Apr 1.

5.

The Virulence Effect of CpxRA in Citrobacter rodentium Is Independent of the Auxiliary Proteins NlpE and CpxP.

Giannakopoulou N, Mendis N, Zhu L, Gruenheid S, Faucher SP, Le Moual H.

Front Cell Infect Microbiol. 2018 Sep 18;8:320. doi: 10.3389/fcimb.2018.00320. eCollection 2018.

6.

Enterobacteria and host resistance to infection.

Kang E, Crouse A, Chevallier L, Pontier SM, Alzahrani A, Silué N, Campbell-Valois FX, Montagutelli X, Gruenheid S, Malo D.

Mamm Genome. 2018 Aug;29(7-8):558-576. doi: 10.1007/s00335-018-9749-4. Epub 2018 May 21. Review.

PMID:
29785663
7.

Salmonella enterica Prophage Sequence Profiles Reflect Genome Diversity and Can Be Used for High Discrimination Subtyping.

Mottawea W, Duceppe MO, Dupras AA, Usongo V, Jeukens J, Freschi L, Emond-Rheault JG, Hamel J, Kukavica-Ibrulj I, Boyle B, Gill A, Burnett E, Franz E, Arya G, Weadge JT, Gruenheid S, Wiedmann M, Huang H, Daigle F, Moineau S, Bekal S, Levesque RC, Goodridge LD, Ogunremi D.

Front Microbiol. 2018 May 4;9:836. doi: 10.3389/fmicb.2018.00836. eCollection 2018.

8.

Loss of disease tolerance during Citrobacter rodentium infection is associated with impaired epithelial differentiation and hyperactivation of T cell responses.

Kang E, Zhou G, Yousefi M, Cayrol R, Xia J, Gruenheid S.

Sci Rep. 2018 Jan 16;8(1):847. doi: 10.1038/s41598-017-17386-y.

9.

A Syst-OMICS Approach to Ensuring Food Safety and Reducing the Economic Burden of Salmonellosis.

Emond-Rheault JG, Jeukens J, Freschi L, Kukavica-Ibrulj I, Boyle B, Dupont MJ, Colavecchio A, Barrere V, Cadieux B, Arya G, Bekal S, Berry C, Burnett E, Cavestri C, Chapin TK, Crouse A, Daigle F, Danyluk MD, Delaquis P, Dewar K, Doualla-Bell F, Fliss I, Fong K, Fournier E, Franz E, Garduno R, Gill A, Gruenheid S, Harris L, Huang CB, Huang H, Johnson R, Joly Y, Kerhoas M, Kong N, Lapointe G, Larivière L, Loignon S, Malo D, Moineau S, Mottawea W, Mukhopadhyay K, Nadon C, Nash J, Ngueng Feze I, Ogunremi D, Perets A, Pilar AV, Reimer AR, Robertson J, Rohde J, Sanderson KE, Song L, Stephan R, Tamber S, Thomassin P, Tremblay D, Usongo V, Vincent C, Wang S, Weadge JT, Wiedmann M, Wijnands L, Wilson ED, Wittum T, Yoshida C, Youfsi K, Zhu L, Weimer BC, Goodridge L, Levesque RC.

Front Microbiol. 2017 Jun 2;8:996. doi: 10.3389/fmicb.2017.00996. eCollection 2017.

10.

Systematic Analysis of Two-Component Systems in Citrobacter rodentium Reveals Positive and Negative Roles in Virulence.

Thomassin JL, Leclerc JM, Giannakopoulou N, Zhu L, Salmon K, Portt A, Daigle F, Le Moual H, Gruenheid S.

Infect Immun. 2017 Jan 26;85(2). pii: e00654-16. doi: 10.1128/IAI.00654-16. Print 2017 Feb.

11.

R-Spondins Are Expressed by the Intestinal Stroma and are Differentially Regulated during Citrobacter rodentium- and DSS-Induced Colitis in Mice.

Kang E, Yousefi M, Gruenheid S.

PLoS One. 2016 Apr 5;11(4):e0152859. doi: 10.1371/journal.pone.0152859. eCollection 2016.

12.

Antimicrobial Peptide Conformation as a Structural Determinant of Omptin Protease Specificity.

Brannon JR, Thomassin JL, Gruenheid S, Le Moual H.

J Bacteriol. 2015 Nov;197(22):3583-91. doi: 10.1128/JB.00469-15. Epub 2015 Sep 8.

13.

Inhibition of outer membrane proteases of the omptin family by aprotinin.

Brannon JR, Burk DL, Leclerc JM, Thomassin JL, Portt A, Berghuis AM, Gruenheid S, Le Moual H.

Infect Immun. 2015 Jun;83(6):2300-11. doi: 10.1128/IAI.00136-15. Epub 2015 Mar 30.

14.

ER egress of invariant chain isoform p35 requires direct binding to MHCII molecules and is inhibited by the NleA virulence factor of enterohaemorrhagic Escherichia coli.

Cloutier M, Gauthier C, Fortin JS, Genève L, Kim K, Gruenheid S, Kim J, Thibodeau J.

Hum Immunol. 2015 Apr;76(4):292-6. doi: 10.1016/j.humimm.2015.02.002. Epub 2015 Feb 27.

PMID:
25731712
15.

The CpxRA two-component system is essential for Citrobacter rodentium virulence.

Thomassin JL, Giannakopoulou N, Zhu L, Gross J, Salmon K, Leclerc JM, Daigle F, Le Moual H, Gruenheid S.

Infect Immun. 2015 May;83(5):1919-28. doi: 10.1128/IAI.00194-15. Epub 2015 Feb 23.

16.

Enterohemorrhagic Escherichia coli OmpT regulates outer membrane vesicle biogenesis.

Premjani V, Tilley D, Gruenheid S, Le Moual H, Samis JA.

FEMS Microbiol Lett. 2014 Jun;355(2):185-92. doi: 10.1111/1574-6968.12463. Epub 2014 May 29.

17.

Contribution of increased ISG15, ISGylation and deregulated type I IFN signaling in Usp18 mutant mice during the course of bacterial infections.

Dauphinee SM, Richer E, Eva MM, McIntosh F, Paquet M, Dangoor D, Burkart C, Zhang DE, Gruenheid S, Gros P, Behr M, Malo D.

Genes Immun. 2014 Jul-Aug;15(5):282-92. doi: 10.1038/gene.2014.17. Epub 2014 May 8.

18.

Both group 4 capsule and lipopolysaccharide O-antigen contribute to enteropathogenic Escherichia coli resistance to human α-defensin 5.

Thomassin JL, Lee MJ, Brannon JR, Sheppard DC, Gruenheid S, Le Moual H.

PLoS One. 2013 Dec 4;8(12):e82475. doi: 10.1371/journal.pone.0082475. eCollection 2013.

19.

[Rspo2 controls C. rodentium infection outcome in mice].

Papapietro O, Gruenheid S.

Med Sci (Paris). 2013 Aug-Sep;29(8-9):688-90. doi: 10.1051/medsci/2013298003. Epub 2013 Sep 5. French. No abstract available.

20.

The inhibition of COPII trafficking is important for intestinal epithelial tight junction disruption during enteropathogenic Escherichia coli and Citrobacter rodentium infection.

Thanabalasuriar A, Kim J, Gruenheid S.

Microbes Infect. 2013 Sep-Oct;15(10-11):738-44. doi: 10.1016/j.micinf.2013.05.001. Epub 2013 Jun 6.

PMID:
23747681
21.

Role of uropathogenic Escherichia coli OmpT in the resistance against human cathelicidin LL-37.

Brannon JR, Thomassin JL, Desloges I, Gruenheid S, Le Moual H.

FEMS Microbiol Lett. 2013 Aug;345(1):64-71. doi: 10.1111/1574-6968.12185. Epub 2013 Jun 13.

22.

R-spondin 2 signalling mediates susceptibility to fatal infectious diarrhoea.

Papapietro O, Teatero S, Thanabalasuriar A, Yuki KE, Diez E, Zhu L, Kang E, Dhillon S, Muise AM, Durocher Y, Marcinkiewicz MM, Malo D, Gruenheid S.

Nat Commun. 2013;4:1898. doi: 10.1038/ncomms2816.

23.

Identification of potentially diarrheagenic atypical enteropathogenic Escherichia coli strains present in Canadian food animals at slaughter and in retail meats.

Comery R, Thanabalasuriar A, Garneau P, Portt A, Boerlin P, Reid-Smith RJ, Harel J, Manges AR, Gruenheid S.

Appl Environ Microbiol. 2013 Jun;79(12):3892-6. doi: 10.1128/AEM.00182-13. Epub 2013 Apr 12.

24.

Enterohemorrhagic and enteropathogenic Escherichia coli evolved different strategies to resist antimicrobial peptides.

Thomassin JL, Brannon JR, Kaiser J, Gruenheid S, Le Moual H.

Gut Microbes. 2012 Nov-Dec;3(6):556-61. doi: 10.4161/gmic.21656. Epub 2012 Aug 16. Review.

25.

Sec24 interaction is essential for localization and virulence-associated function of the bacterial effector protein NleA.

Thanabalasuriar A, Bergeron J, Gillingham A, Mimee M, Thomassin JL, Strynadka N, Kim J, Gruenheid S.

Cell Microbiol. 2012 Aug;14(8):1206-18. doi: 10.1111/j.1462-5822.2012.01789.x. Epub 2012 Apr 12.

PMID:
22432415
26.

An N-ethyl-N-nitrosourea (ENU)-induced dominant negative mutation in the JAK3 kinase protects against cerebral malaria.

Bongfen SE, Rodrigue-Gervais IG, Berghout J, Torre S, Cingolani P, Wiltshire SA, Leiva-Torres GA, Letourneau L, Sladek R, Blanchette M, Lathrop M, Behr MA, Gruenheid S, Vidal SM, Saleh M, Gros P.

PLoS One. 2012;7(2):e31012. doi: 10.1371/journal.pone.0031012. Epub 2012 Feb 21.

27.

Resistance to antimicrobial peptides in Gram-negative bacteria.

Gruenheid S, Le Moual H.

FEMS Microbiol Lett. 2012 May;330(2):81-9. doi: 10.1111/j.1574-6968.2012.02528.x. Epub 2012 Mar 12. Review.

28.

OmpT outer membrane proteases of enterohemorrhagic and enteropathogenic Escherichia coli contribute differently to the degradation of human LL-37.

Thomassin JL, Brannon JR, Gibbs BF, Gruenheid S, Le Moual H.

Infect Immun. 2012 Feb;80(2):483-92. doi: 10.1128/IAI.05674-11. Epub 2011 Dec 5.

29.

Perturbation of host cell cytoskeleton by cranberry proanthocyanidins and their effect on enteric infections.

Harmidy K, Tufenkji N, Gruenheid S.

PLoS One. 2011;6(11):e27267. doi: 10.1371/journal.pone.0027267. Epub 2011 Nov 4.

30.

The Cri1 locus is the common genetic cause of susceptibility to Citrobacter rodentium infection in C3H and FVB mouse strains.

Teatero SA, Thomassin JL, Zhu L, Diez E, Malo D, Gruenheid S.

Gut Microbes. 2011 May-Jun;2(3):173-7. Epub 2011 May 1.

PMID:
21804358
31.
32.

Identification and characterization of Cri1, a locus controlling mortality during Citrobacter rodentium infection in mice.

Diez E, Zhu L, Teatero SA, Paquet M, Roy MF, Loredo-Osti JC, Malo D, Gruenheid S.

Genes Immun. 2011 Jun;12(4):280-90. doi: 10.1038/gene.2010.76. Epub 2011 Feb 17.

PMID:
21326319
33.

Forward genetic dissection of innate response to infection in inbred mouse strains: selected success stories.

Gruenheid S, Gros P.

Clin Exp Immunol. 2010 Dec;162(3):393-401. doi: 10.1111/j.1365-2249.2010.04249.x. Review.

34.

Antibacterial autophagy occurs at PI(3)P-enriched domains of the endoplasmic reticulum and requires Rab1 GTPase.

Huang J, Birmingham CL, Shahnazari S, Shiu J, Zheng YT, Smith AC, Campellone KG, Heo WD, Gruenheid S, Meyer T, Welch MD, Ktistakis NT, Kim PK, Klionsky DJ, Brumell JH.

Autophagy. 2011 Jan;7(1):17-26. Epub 2011 Jan 1.

35.

The bacterial virulence factor NleA is required for the disruption of intestinal tight junctions by enteropathogenic Escherichia coli.

Thanabalasuriar A, Koutsouris A, Weflen A, Mimee M, Hecht G, Gruenheid S.

Cell Microbiol. 2010 Jan;12(1):31-41. doi: 10.1111/j.1462-5822.2009.01376.x. Epub 2009 Aug 27.

36.

An outer membrane protease of the omptin family prevents activation of the Citrobacter rodentium PhoPQ two-component system by antimicrobial peptides.

Le Sage V, Zhu L, Lepage C, Portt A, Viau C, Daigle F, Gruenheid S, Le Moual H.

Mol Microbiol. 2009 Oct;74(1):98-111. doi: 10.1111/j.1365-2958.2009.06854.x. Epub 2009 Aug 24.

37.

Use of Nramp2-transfected Chinese hamster ovary cells and reticulocytes from mk/mk mice to study iron transport mechanisms.

Zhang AS, Canonne-Hergaux F, Gruenheid S, Gros P, Ponka P.

Exp Hematol. 2008 Oct;36(10):1227-35. doi: 10.1016/j.exphem.2008.04.014. Epub 2008 Aug 22.

38.

Impact of temperature on biodegradation of bulk and trace organics during soil passage in an indirect reuse system.

Gruenheid S, Huebner U, Jekel M.

Water Sci Technol. 2008;57(7):987-94. doi: 10.2166/wst.2008.207.

PMID:
18441423
39.

Caspase-12 modulates NOD signaling and regulates antimicrobial peptide production and mucosal immunity.

LeBlanc PM, Yeretssian G, Rutherford N, Doiron K, Nadiri A, Zhu L, Green DR, Gruenheid S, Saleh M.

Cell Host Microbe. 2008 Mar 13;3(3):146-57. doi: 10.1016/j.chom.2008.02.004.

40.

Characterization of the NleF effector protein from attaching and effacing bacterial pathogens.

Echtenkamp F, Deng W, Wickham ME, Vazquez A, Puente JL, Thanabalasuriar A, Gruenheid S, Finlay BB, Hardwidge PR.

FEMS Microbiol Lett. 2008 Apr;281(1):98-107. doi: 10.1111/j.1574-6968.2008.01088.x.

41.

Molecular analysis as an aid to assess the public health risk of non-O157 Shiga toxin-producing Escherichia coli strains.

Coombes BK, Wickham ME, Mascarenhas M, Gruenheid S, Finlay BB, Karmali MA.

Appl Environ Microbiol. 2008 Apr;74(7):2153-60. doi: 10.1128/AEM.02566-07. Epub 2008 Feb 1.

42.

Phosphorylated YDXV motifs and Nck SH2/SH3 adaptors act cooperatively to induce actin reorganization.

Blasutig IM, New LA, Thanabalasuriar A, Dayarathna TK, Goudreault M, Quaggin SE, Li SS, Gruenheid S, Jones N, Pawson T.

Mol Cell Biol. 2008 Mar;28(6):2035-46. doi: 10.1128/MCB.01770-07. Epub 2008 Jan 22.

43.

The bacterial virulence factor NleA inhibits cellular protein secretion by disrupting mammalian COPII function.

Kim J, Thanabalasuriar A, Chaworth-Musters T, Fromme JC, Frey EA, Lario PI, Metalnikov P, Rizg K, Thomas NA, Lee SF, Hartland EL, Hardwidge PR, Pawson T, Strynadka NC, Finlay BB, Schekman R, Gruenheid S.

Cell Host Microbe. 2007 Sep 13;2(3):160-71.

44.

Regulation of type III secretion hierarchy of translocators and effectors in attaching and effacing bacterial pathogens.

Deng W, Li Y, Hardwidge PR, Frey EA, Pfuetzner RA, Lee S, Gruenheid S, Strynakda NC, Puente JL, Finlay BB.

Infect Immun. 2005 Apr;73(4):2135-46.

45.

Dissecting virulence: systematic and functional analyses of a pathogenicity island.

Deng W, Puente JL, Gruenheid S, Li Y, Vallance BA, Vázquez A, Barba J, Ibarra JA, O'Donnell P, Metalnikov P, Ashman K, Lee S, Goode D, Pawson T, Finlay BB.

Proc Natl Acad Sci U S A. 2004 Mar 9;101(10):3597-602. Epub 2004 Feb 26.

46.

Identification and characterization of NleA, a non-LEE-encoded type III translocated virulence factor of enterohaemorrhagic Escherichia coli O157:H7.

Gruenheid S, Sekirov I, Thomas NA, Deng W, O'Donnell P, Goode D, Li Y, Frey EA, Brown NF, Metalnikov P, Pawson T, Ashman K, Finlay BB.

Mol Microbiol. 2004 Mar;51(5):1233-49.

47.

Microbial pathogenesis and cytoskeletal function.

Gruenheid S, Finlay BB.

Nature. 2003 Apr 17;422(6933):775-81. Review.

PMID:
12700772
48.

Iron transporter Nramp2/DMT-1 is associated with the membrane of phagosomes in macrophages and Sertoli cells.

Jabado N, Canonne-Hergaux F, Gruenheid S, Picard V, Gros P.

Blood. 2002 Oct 1;100(7):2617-22.

PMID:
12239176
49.

Delivery of dangerous goods: type III secretion in enteric pathogens.

Zaharik ML, Gruenheid S, Perrin AJ, Finlay BB.

Int J Med Microbiol. 2002 Mar;291(8):593-603. Review.

PMID:
12008913
50.

Enteropathogenic E. coli Tir binds Nck to initiate actin pedestal formation in host cells.

Gruenheid S, DeVinney R, Bladt F, Goosney D, Gelkop S, Gish GD, Pawson T, Finlay BB.

Nat Cell Biol. 2001 Sep;3(9):856-9.

PMID:
11533668

Supplemental Content

Loading ...
Support Center