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Items: 1 to 50 of 187

1.

Drug-induced increase in lysobisphosphatidic acid reduces the cholesterol overload in Niemann-Pick type C cells and mice.

Moreau D, Vacca F, Vossio S, Scott C, Colaco A, Paz Montoya J, Ferguson C, Damme M, Moniatte M, Parton RG, Platt FM, Gruenberg J.

EMBO Rep. 2019 Jul;20(7):e47055. doi: 10.15252/embr.201847055. Epub 2019 May 22.

2.

Drug-induced increase in lysobisphosphatidic acid reduces the cholesterol overload in Niemann-Pick type C cells and mice.

Moreau D, Vacca F, Vossio S, Scott C, Colaco A, Paz Montoya J, Ferguson C, Damme M, Moniatte M, Parton RG, Platt FM, Gruenberg J.

EMBO Rep. 2019 May 22. pii: e47055. doi: 10.15252/embr.201847055. [Epub ahead of print]

3.

Disseminated Hormographiella aspergillata Infection with Lung and Brain Involvement after Allogenic Hematopoietic Stem-Cell Transplantation in a 54-Year-Old Man.

Chauhan A, Gruenberg J, Arbefeville S, Mettler T, Brent CH, Ferrieri P.

Lab Med. 2019 May 8. pii: lmz018. doi: 10.1093/labmed/lmz018. [Epub ahead of print]

PMID:
31065690
4.

Cyclodextrin triggers MCOLN1-dependent endo-lysosome secretion in Niemann-Pick type C cells.

Vacca F, Vossio S, Mercier V, Moreau D, Johnson S, Scott CC, Montoya JP, Moniatte M, Gruenberg J.

J Lipid Res. 2019 Apr;60(4):832-843. doi: 10.1194/jlr.M089979. Epub 2019 Feb 1.

PMID:
30709900
5.

The topology of the lymphotoxin β receptor that accumulates upon endolysosomal dysfunction dictates the NF-κB signaling outcome.

Banach-Orłowska M, Jastrzębski K, Cendrowski J, Maksymowicz M, Wojciechowska K, Korostyński M, Moreau D, Gruenberg J, Miaczynska M.

J Cell Sci. 2018 Nov 21;131(22). pii: jcs218883. doi: 10.1242/jcs.218883.

6.

TFAP2 transcription factors are regulators of lipid droplet biogenesis.

Scott CC, Vossio S, Rougemont J, Gruenberg J.

Elife. 2018 Sep 26;7. pii: e36330. doi: 10.7554/eLife.36330.

7.

Phosphorylation of conserved phosphoinositide binding pocket regulates sorting nexin membrane targeting.

Lenoir M, Ustunel C, Rajesh S, Kaur J, Moreau D, Gruenberg J, Overduin M.

Nat Commun. 2018 Mar 8;9(1):993. doi: 10.1038/s41467-018-03370-1.

8.

Determining the utility of creatinine delta checks: A large retrospective analysis.

Gruenberg JM, Stein TA, Karger AB.

Clin Biochem. 2018 Mar;53:139-142. doi: 10.1016/j.clinbiochem.2018.01.023. Epub 2018 Feb 1.

PMID:
29402415
9.

In Vitro Polymerization of F-actin on Early Endosomes.

Muriel O, Scott CC, Larios J, Mercier V, Gruenberg J.

J Vis Exp. 2017 Aug 28;(126). doi: 10.3791/55829.

PMID:
28872124
10.

L-leucyl-L-leucine methyl ester does not release cysteine cathepsins to the cytosol but inactivates them in transiently permeabilized lysosomes.

Repnik U, Borg Distefano M, Speth MT, Ng MYW, Progida C, Hoflack B, Gruenberg J, Griffiths G.

J Cell Sci. 2017 Sep 15;130(18):3124-3140. doi: 10.1242/jcs.204529. Epub 2017 Jul 28.

11.

Automated Microscopy and High Content Screens (Phenotypic Screens) in Academia Labs.

Moreau D, Gruenberg J.

Chimia (Aarau). 2016 Dec 21;70(12):878-882. doi: 10.2533/chimia.2016.878. Review.

PMID:
28661361
12.

Moesin and cortactin control actin-dependent multivesicular endosome biogenesis.

Muriel O, Tomas A, Scott CC, Gruenberg J.

Mol Biol Cell. 2016 Nov 1;27(21):3305-3316. Epub 2016 Sep 7.

13.

Selective Imaging of Late Endosomes with a pH-Sensitive Diazaoxatriangulene Fluorescent Probe.

Wallabregue A, Moreau D, Sherin P, Moneva Lorente P, Jarolímová Z, Bakker E, Vauthey E, Gruenberg J, Lacour J.

J Am Chem Soc. 2016 Feb 17;138(6):1752-5. doi: 10.1021/jacs.5b09972. Epub 2016 Feb 5.

PMID:
26799309
14.

Fatal acute cardiac vasculopathy during cisplatin-gemcitabine-bevacizumab (CGB) chemotherapy for advanced urothelial carcinoma.

Gruenberg J, Manivel JC, Gupta P, Dykoski R, Mesa H.

J Infect Chemother. 2016 Feb;22(2):112-6. doi: 10.1016/j.jiac.2015.08.015. Epub 2015 Sep 28.

PMID:
26423690
15.

Secondary structure and (1)H, (13)C, (15)N resonance assignments of the endosomal sorting protein sorting nexin 3.

Overduin M, Rajesh S, Gruenberg J, Lenoir M.

Biomol NMR Assign. 2015 Oct;9(2):355-8. doi: 10.1007/s12104-015-9609-z. Epub 2015 Apr 19.

16.

Wnt directs the endosomal flux of LDL-derived cholesterol and lipid droplet homeostasis.

Scott CC, Vossio S, Vacca F, Snijder B, Larios J, Schaad O, Guex N, Kuznetsov D, Martin O, Chambon M, Turcatti G, Pelkmans L, Gruenberg J.

EMBO Rep. 2015 Jun;16(6):741-52. doi: 10.15252/embr.201540081. Epub 2015 Apr 7.

17.

Close encounter of the third kind: the ER meets endosomes at fission sites.

van der Goot FG, Gruenberg J.

Dev Cell. 2014 Dec 22;31(6):673-4. doi: 10.1016/j.devcel.2014.12.008.

18.

Discovery of novel membrane binding structures and functions.

Kufareva I, Lenoir M, Dancea F, Sridhar P, Raush E, Bissig C, Gruenberg J, Abagyan R, Overduin M.

Biochem Cell Biol. 2014 Dec;92(6):555-63. doi: 10.1139/bcb-2014-0074. Epub 2014 Sep 18.

19.

Endosome maturation, transport and functions.

Scott CC, Vacca F, Gruenberg J.

Semin Cell Dev Biol. 2014 Jul;31:2-10. doi: 10.1016/j.semcdb.2014.03.034. Epub 2014 Apr 4. Review.

PMID:
24709024
20.

ALIX and the multivesicular endosome: ALIX in Wonderland.

Bissig C, Gruenberg J.

Trends Cell Biol. 2014 Jan;24(1):19-25. doi: 10.1016/j.tcb.2013.10.009. Epub 2013 Nov 26. Review.

PMID:
24287454
21.

Lipid sorting and multivesicular endosome biogenesis.

Bissig C, Gruenberg J.

Cold Spring Harb Perspect Biol. 2013 Oct 1;5(10):a016816. doi: 10.1101/cshperspect.a016816. Review.

22.

Viral infection controlled by a calcium-dependent lipid-binding module in ALIX.

Bissig C, Lenoir M, Velluz MC, Kufareva I, Abagyan R, Overduin M, Gruenberg J.

Dev Cell. 2013 May 28;25(4):364-73. doi: 10.1016/j.devcel.2013.04.003. Epub 2013 May 9.

23.

PNPLA3/adiponutrin functions in lipid droplet formation.

Chamoun Z, Vacca F, Parton RG, Gruenberg J.

Biol Cell. 2013 May;105(5):219-233. doi: 10.1111/boc.201200036. Epub 2013 Apr 17.

PMID:
23398201
24.

An MBoC favorite: Functional interactions between sphingolipids and sterols in biological membranes regulating cell physiology.

Gruenberg J.

Mol Biol Cell. 2012 Jul;23(13):2402. doi: 10.1091/mbc.E12-03-0190. No abstract available.

25.

SNX12 role in endosome membrane transport.

Pons V, Ustunel C, Rolland C, Torti E, Parton RG, Gruenberg J.

PLoS One. 2012;7(6):e38949. doi: 10.1371/journal.pone.0038949. Epub 2012 Jun 15.

26.

Single-cell analysis of population context advances RNAi screening at multiple levels.

Snijder B, Sacher R, Rämö P, Liberali P, Mench K, Wolfrum N, Burleigh L, Scott CC, Verheije MH, Mercer J, Moese S, Heger T, Theusner K, Jurgeit A, Lamparter D, Balistreri G, Schelhaas M, De Haan CA, Marjomäki V, Hyypiä T, Rottier PJ, Sodeik B, Marsh M, Gruenberg J, Amara A, Greber U, Helenius A, Pelkmans L.

Mol Syst Biol. 2012 Apr 24;8:579. doi: 10.1038/msb.2012.9.

27.

Regulation of the EGF transcriptional response by endocytic sorting.

Brankatschk B, Wichert SP, Johnson SD, Schaad O, Rossner MJ, Gruenberg J.

Sci Signal. 2012 Mar 13;5(215):ra21. doi: 10.1126/scisignal.2002351.

28.

Studying lipids involved in the endosomal pathway.

Bissig C, Johnson S, Gruenberg J.

Methods Cell Biol. 2012;108:19-46. doi: 10.1016/B978-0-12-386487-1.00002-X. Review.

PMID:
22325596
29.

A novel strategy to identify drugs that interfere with endosomal lipids.

Moreau D, Scott C, Gruenberg J.

Chimia (Aarau). 2011;65(11):846-8. doi: 10.2533/chimia.2011.846. Review.

PMID:
22289369
30.

Duelling functions of the V-ATPase.

Scott CC, Bissig C, Gruenberg J.

EMBO J. 2011 Oct 19;30(20):4113-5. doi: 10.1038/emboj.2011.355. No abstract available.

31.

Regulation of the MVB pathway by SCAMP3.

Falguières T, Castle D, Gruenberg J.

Traffic. 2012 Jan;13(1):131-42. doi: 10.1111/j.1600-0854.2011.01291.x. Epub 2011 Oct 18.

32.

Role of SNX16 in the dynamics of tubulo-cisternal membrane domains of late endosomes.

Brankatschk B, Pons V, Parton RG, Gruenberg J.

PLoS One. 2011;6(7):e21771. doi: 10.1371/journal.pone.0021771. Epub 2011 Jul 6.

33.

Role of AP1 and Gadkin in the traffic of secretory endo-lysosomes.

Laulagnier K, Schieber NL, Maritzen T, Haucke V, Parton RG, Gruenberg J.

Mol Biol Cell. 2011 Jun 15;22(12):2068-82. doi: 10.1091/mbc.E11-03-0193. Epub 2011 Apr 27.

35.

Structure, dynamics, and energetics of lysobisphosphatidic acid (LBPA) isomers.

Goursot A, Mineva T, Bissig C, Gruenberg J, Salahub DR.

J Phys Chem B. 2010 Dec 2;114(47):15712-20. doi: 10.1021/jp108361d. Epub 2010 Nov 5.

PMID:
21053942
36.

The Biochemistry Department of the University of Geneva: Understanding the Molecular Basis and Function of Intracellular Organization.

González-Gaitán M, Gruenberg J, Halazonetis T, Laemmli UK, Matter JM, Riezman H, Schaad O, Soldati T, Watanabe R.

Chimia (Aarau). 2009 Dec 1;63(12):830-834. doi: 10.2533/chimia.2009.830.

PMID:
28372605
37.

Viruses and endosome membrane dynamics.

Gruenberg J.

Curr Opin Cell Biol. 2009 Aug;21(4):582-8. doi: 10.1016/j.ceb.2009.03.008. Epub 2009 May 13. Review.

PMID:
19443190
38.

Annexin A2-dependent polymerization of actin mediates endosome biogenesis.

Morel E, Parton RG, Gruenberg J.

Dev Cell. 2009 Mar;16(3):445-57. doi: 10.1016/j.devcel.2009.01.007.

39.

Molecular assemblies and membrane domains in multivesicular endosome dynamics.

Falguières T, Luyet PP, Gruenberg J.

Exp Cell Res. 2009 May 15;315(9):1567-73. doi: 10.1016/j.yexcr.2008.12.006. Epub 2008 Dec 24. Review.

PMID:
19133258
40.

Annexin A2 binding to endosomes and functions in endosomal transport are regulated by tyrosine 23 phosphorylation.

Morel E, Gruenberg J.

J Biol Chem. 2009 Jan 16;284(3):1604-11. doi: 10.1074/jbc.M806499200. Epub 2008 Nov 5.

41.

The ESCRT-I subunit TSG101 controls endosome-to-cytosol release of viral RNA.

Luyet PP, Falguières T, Pons V, Pattnaik AK, Gruenberg J.

Traffic. 2008 Dec;9(12):2279-90. doi: 10.1111/j.1600-0854.2008.00820.x. Epub 2008 Sep 24.

42.

In vitro budding of intralumenal vesicles into late endosomes is regulated by Alix and Tsg101.

Falguières T, Luyet PP, Bissig C, Scott CC, Velluz MC, Gruenberg J.

Mol Biol Cell. 2008 Nov;19(11):4942-55. doi: 10.1091/mbc.E08-03-0239. Epub 2008 Sep 3.

43.

Hrs and SNX3 functions in sorting and membrane invagination within multivesicular bodies.

Pons V, Luyet PP, Morel E, Abrami L, van der Goot FG, Parton RG, Gruenberg J.

PLoS Biol. 2008 Sep 2;6(9):e214. doi: 10.1371/journal.pbio.0060214.

44.

Lysobisphosphatidic acid controls endosomal cholesterol levels.

Chevallier J, Chamoun Z, Jiang G, Prestwich G, Sakai N, Matile S, Parton RG, Gruenberg J.

J Biol Chem. 2008 Oct 10;283(41):27871-80. doi: 10.1074/jbc.M801463200. Epub 2008 Jul 21.

45.

Down syndrome fibroblast model of Alzheimer-related endosome pathology: accelerated endocytosis promotes late endocytic defects.

Cataldo AM, Mathews PM, Boiteau AB, Hassinger LC, Peterhoff CM, Jiang Y, Mullaney K, Neve RL, Gruenberg J, Nixon RA.

Am J Pathol. 2008 Aug;173(2):370-84. doi: 10.2353/ajpath.2008.071053. Epub 2008 Jun 5.

46.

Subcellular fractionation of tissue culture cells.

Aniento F, Gruenberg J.

Curr Protoc Immunol. 2003 Nov;Chapter 8:Unit 8.1C. doi: 10.1002/0471142735.im0801cs57. Review.

PMID:
18432914
47.

Subcellular fractionation of tissue culture cells.

Aniento F, Gruenberg J.

Curr Protoc Protein Sci. 2004 Aug;Chapter 4:Unit 4.3. doi: 10.1002/0471140864.ps0403s32.

PMID:
18429269
48.

The cargo receptors Surf4, endoplasmic reticulum-Golgi intermediate compartment (ERGIC)-53, and p25 are required to maintain the architecture of ERGIC and Golgi.

Mitrovic S, Ben-Tekaya H, Koegler E, Gruenberg J, Hauri HP.

Mol Biol Cell. 2008 May;19(5):1976-90. doi: 10.1091/mbc.E07-10-0989. Epub 2008 Feb 20.

49.

The redox sensor TXNL1 plays a regulatory role in fluid phase endocytosis.

Felberbaum-Corti M, Morel E, Cavalli V, Vilbois F, Gruenberg J.

PLoS One. 2007 Nov 7;2(11):e1144.

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