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Items: 7


Thioridazine inhibits autophagy and sensitizes glioblastoma cells to temozolomide.

Johannessen TC, Hasan-Olive MM, Zhu H, Denisova O, Grudic A, Latif MA, Saed H, Varughese JK, Røsland GV, Yang N, Sundstrøm T, Nordal A, Tronstad KJ, Wang J, Lund-Johansen M, Simonsen A, Janji B, Westermarck J, Bjerkvig R, Prestegarden L.

Int J Cancer. 2019 Apr 1;144(7):1735-1745. doi: 10.1002/ijc.31912. Epub 2018 Dec 11.


The DNA repair protein ALKBH2 mediates temozolomide resistance in human glioblastoma cells.

Johannessen TC, Prestegarden L, Grudic A, Hegi ME, Tysnes BB, Bjerkvig R.

Neuro Oncol. 2013 Mar;15(3):269-78. doi: 10.1093/neuonc/nos301. Epub 2012 Dec 20.


The arsenic-based cure of acute promyelocytic leukemia promotes cytoplasmic sequestration of PML and PML/RARA through inhibition of PML body recycling.

Lång E, Grudic A, Pankiv S, Bruserud O, Simonsen A, Bjerkvig R, Bjørås M, Bøe SO.

Blood. 2012 Jul 26;120(4):847-57. doi: 10.1182/blood-2011-10-388496. Epub 2012 Jun 12.


Subcellular distribution of nuclear import-defective isoforms of the promyelocytic leukemia protein.

Jul-Larsen A, Grudic A, Bjerkvig R, Bøe SO.

BMC Mol Biol. 2010 Nov 21;11:89. doi: 10.1186/1471-2199-11-89.


Cell-cycle regulation and dynamics of cytoplasmic compartments containing the promyelocytic leukemia protein and nucleoporins.

Jul-Larsen A, Grudic A, Bjerkvig R, Bøe SO.

J Cell Sci. 2009 Apr 15;122(Pt 8):1201-10. doi: 10.1242/jcs.040840.


Replication protein A prevents accumulation of single-stranded telomeric DNA in cells that use alternative lengthening of telomeres.

Grudic A, Jul-Larsen A, Haring SJ, Wold MS, Lønning PE, Bjerkvig R, Bøe SO.

Nucleic Acids Res. 2007;35(21):7267-78. Epub 2007 Oct 24.


Promyelocytic leukemia nuclear bodies are predetermined processing sites for damaged DNA.

Bøe SO, Haave M, Jul-Larsen A, Grudic A, Bjerkvig R, Lønning PE.

J Cell Sci. 2006 Aug 15;119(Pt 16):3284-95. Epub 2006 Jul 25.

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