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Clinical and Genetic Spectrum of a Large Cohort With Total and Sub-total Complement Deficiencies.

El Sissy C, Rosain J, Vieira-Martins P, Bordereau P, Gruber A, Devriese M, de Pontual L, Taha MK, Fieschi C, Picard C, Frémeaux-Bacchi V.

Front Immunol. 2019 Aug 8;10:1936. doi: 10.3389/fimmu.2019.01936. eCollection 2019.


Morphology, Ultrastructure, and Mitochondrial Genome of the Marine Non-Photosynthetic Bicosoecid Cafileria marina Gen. et sp. nov.

Jirsová D, Füssy Z, Richtová J, Gruber A, Oborník M.

Microorganisms. 2019 Aug 5;7(8). pii: E240. doi: 10.3390/microorganisms7080240.


Characterization of Aminoacyl-tRNA Synthetases in Chromerids.

Sharaf A, Gruber A, Jiroutová K, Oborník M.

Genes (Basel). 2019 Jul 31;10(8). pii: E582. doi: 10.3390/genes10080582.


Uncertainty in Soil Moisture Retrievals: an Ensemble Approach using SMOS L-Band Microwave Data.

Quets J, De Lannoy GJM, Al Yaari A, Chan S, Cosh MH, Gruber A, Reichle RH, Van der Schalie R, Wigneron JP.

Remote Sens Environ. 2019 Aug;229:133-147. doi: 10.1016/j.rse.2019.05.008. Epub 2019 May 15.


Agricultural exposures to carbamate herbicides and fungicides and central nervous system tumour incidence in the cohort AGRICAN.

Piel C, Pouchieu C, Carles C, Béziat B, Boulanger M, Bureau M, Busson A, Grüber A, Lecluse Y, Migault L, Renier M, Rondeau V, Schwall X, Tual S; AGRICAN group, Pierre L, Baldi I.

Environ Int. 2019 Sep;130:104876. doi: 10.1016/j.envint.2019.05.070. Epub 2019 Jul 22.


Alternative cleavage and polyadenylation in health and disease.

Gruber AJ, Zavolan M.

Nat Rev Genet. 2019 Jul 2. doi: 10.1038/s41576-019-0145-z. [Epub ahead of print] Review.


Plasmacytoid dendritic cell depletion modifies FoxP3+ T cell homeostasis and the clinical course of bacterial pneumonia in mice.

Lippitsch A, Baal N, Chukovetskyi Y, Cunningham S, Michel G, Dietert K, Gurtner C, Gruber AD, Bein G, Hackstein H.

J Leukoc Biol. 2019 Jul 2. doi: 10.1002/JLB.3AB0119-014RR. [Epub ahead of print]


Loss of ASAP1 in mice impairs adipogenic and osteogenic differentiation of mesenchymal progenitor cells through dysregulation of FAK/Src and AKT signaling.

Schreiber C, Saraswati S, Harkins S, Gruber A, Cremers N, Thiele W, Rothley M, Plaumann D, Korn C, Armant O, Augustin HG, Sleeman JP.

PLoS Genet. 2019 Jun 27;15(6):e1008216. doi: 10.1371/journal.pgen.1008216. eCollection 2019 Jun.


Endothelial PAI-1 (Plasminogen Activator Inhibitor-1) Blocks the Intrinsic Pathway of Coagulation, Inducing the Clearance and Degradation of FXIa (Activated Factor XI).

Puy C, Ngo ATP, Pang J, Keshari RS, Hagen MW, Hinds MT, Gailani D, Gruber A, Lupu F, McCarty OJT.

Arterioscler Thromb Vasc Biol. 2019 Jul;39(7):1390-1401. doi: 10.1161/ATVBAHA.119.312619. Epub 2019 May 23.


Distributed Encoding of Reinforcement in Rat Cortico-Striatal-Limbic Networks.

Donovan CH, Badenhorst CA, Gruber AJ.

Neuroscience. 2019 Aug 10;413:169-182. doi: 10.1016/j.neuroscience.2019.06.019. Epub 2019 Jun 21.


Equine Idiopathic Hemorrhagic Cystitis: Is It Idiopathic or More Likely to Be Exercise-Associated?

Barton AK, Kershaw O, Gruber AD, Gehlen H.

J Equine Vet Sci. 2019 Jul;78:6-9. doi: 10.1016/j.jevs.2019.03.212. Epub 2019 Apr 4.


NF1 mutations identify molecular and clinical subtypes of lung adenocarcinomas.

Tlemsani C, Pécuchet N, Gruber A, Laurendeau I, Danel C, Riquet M, Le Pimpec-Barthes F, Fabre E, Mansuet-Lupo A, Damotte D, Alifano M, Luscan A, Rousseau B, Vidaud D, Varin J, Parfait B, Bieche I, Leroy K, Laurent-Puig P, Terris B, Blons H, Vidaud M, Pasmant E.

Cancer Med. 2019 Aug;8(9):4330-4337. doi: 10.1002/cam4.2175. Epub 2019 Jun 14.


Organelle Studies and Proteome Analyses of Mitochondria and Plastids Fractions from the Diatom Thalassiosira pseudonana.

Schober AF, Rï O Bï Rtulos C, Bischoff A, Lepetit B, Gruber A, Kroth PG.

Plant Cell Physiol. 2019 Aug 1;60(8):1811-1828. doi: 10.1093/pcp/pcz097.


Most marathon runners at the 2017 IAAF World Championships were rearfoot strikers, and most did not change footstrike pattern.

Hanley B, Bissas A, Merlino S, Gruber AH.

J Biomech. 2019 Jul 19;92:54-60. doi: 10.1016/j.jbiomech.2019.05.024. Epub 2019 May 22.


A non-circulating pool of factor XI associated with glycosaminoglycans in mice.

Mohammed BM, Cheng Q, Matafonov A, Verhamme IM, Emsley J, McCrae KR, McCarty OJT, Gruber A, Gailani D.

J Thromb Haemost. 2019 May 24. doi: 10.1111/jth.14494. [Epub ahead of print]


Aging and Senescence in Canine Testes.

Merz SE, Klopfleisch R, Breithaupt A, Gruber AD.

Vet Pathol. 2019 Sep;56(5):715-724. doi: 10.1177/0300985819843683. Epub 2019 May 6.


The influence of age on the peri- and postoperative clinical course in patients undergoing minimally invasive transforaminal lumbar interbody fusion techniques of the lumbar spine.

Senker W, Stefanits H, Gmeiner M, Trutschnig W, Radl C, Gruber A.

Clin Neurol Neurosurg. 2019 Jul;182:25-31. doi: 10.1016/j.clineuro.2019.04.025. Epub 2019 Apr 30.


Effect of the additional cysteine 503 of vancomycin-resistant Enterococcus faecalis (V583) alkylhydroperoxide reductase subunit F (AhpF) and the mechanism of AhpF and subunit C assembling.

Toh YK, Shin J, Balakrishna AM, Kamariah N, Grüber A, Eisenhaber F, Eisenhaber B, Grüber G.

Free Radic Biol Med. 2019 Jul;138:10-22. doi: 10.1016/j.freeradbiomed.2019.04.036. Epub 2019 Apr 30.


High prevalence of Sarcocystis calchasi in racing pigeon flocks in Germany.

Parmentier SL, Maier-Sam K, Failing K, Gruber AD, Lierz M.

PLoS One. 2019 Apr 15;14(4):e0215241. doi: 10.1371/journal.pone.0215241. eCollection 2019.


ATP13A2 missense variant in Australian Cattle Dogs with late onset neuronal ceroid lipofuscinosis.

Schmutz I, Jagannathan V, Bartenschlager F, Stein VM, Gruber AD, Leeb T, Katz ML.

Mol Genet Metab. 2019 May;127(1):95-106. doi: 10.1016/j.ymgme.2018.11.015. Epub 2019 Mar 27.


Soft X-ray microscopy for probing of topical tacrolimus delivery via micelles.

Yamamoto K, Klossek A, Fuchs K, Watts B, Raabe J, Flesch R, Rancan F, Pischon H, Radbruch M, Gruber AD, Mundhenk L, Vogt A, Blume-Peytavi U, Schrade P, Bachmann S, Gurny R, Rühl E.

Eur J Pharm Biopharm. 2019 Jun;139:68-75. doi: 10.1016/j.ejpb.2019.03.006. Epub 2019 Mar 6.


Efficacy and safety of oral alitretinoin as treatment for chronic hand eczema in France: a real-life open-label study.

Halioua B, Paul C, Berbis P, Cambazard F, Doutre MS, Joly P, Richard MA, Aubin C, Gruber A, Chosidow O.

Eur J Dermatol. 2019 Feb 1;29(1):59-66. doi: 10.1684/ejd.2018.3484.


Inhibition of contact-mediated activation of factor XI protects baboons against S aureus-induced organ damage and death.

Silasi R, Keshari RS, Lupu C, Van Rensburg WJ, Chaaban H, Regmi G, Shamanaev A, Shatzel JJ, Puy C, Lorentz CU, Tucker EI, Gailani D, Gruber A, McCarty OJT, Lupu F.

Blood Adv. 2019 Feb 26;3(4):658-669. doi: 10.1182/bloodadvances.2018029983.


Phase of electroencephalography theta oscillation during stimulus encoding affects accuracy of memory recall.

Jalali A, Tata MS, Gruber AJ, Luczak A.

Neuroreport. 2019 Apr 10;30(6):404-408. doi: 10.1097/WNR.0000000000001215.


Pharmacodynamic Study of Miransertib in Individuals with Proteus Syndrome.

Keppler-Noreuil KM, Sapp JC, Lindhurst MJ, Darling TN, Burton-Akright J, Bagheri M, Dombi E, Gruber A, Jarosinski PF, Martin S, Nathan N, Paul SM, Savage RE, Wolters PL, Schwartz B, Widemann BC, Biesecker LG.

Am J Hum Genet. 2019 Mar 7;104(3):484-491. doi: 10.1016/j.ajhg.2019.01.015. Epub 2019 Feb 22.


Pseudogout - periarticular calcium pyrophosphate crystal deposition disease in a dog.

Bertram CA, Burger M, Raila G, Zentek J, Gruber AD.

J Small Anim Pract. 2019 May;60(5):323. doi: 10.1111/jsap.12981. Epub 2019 Feb 18. No abstract available.


Infectious complications and NK cell depletion following daratumumab treatment of Multiple Myeloma.

Nahi H, Chrobok M, Gran C, Lund J, Gruber A, Gahrton G, Ljungman P, Wagner AK, Alici E.

PLoS One. 2019 Feb 13;14(2):e0211927. doi: 10.1371/journal.pone.0211927. eCollection 2019.


What's in a name? How organelles of endosymbiotic origin can be distinguished from endosymbionts.

Gruber A.

Microb Cell. 2019 Jan 21;6(2):123-133. doi: 10.15698/mic2019.02.668.


Acute Moraxella catarrhalis Airway Infection of Chronically Smoke-Exposed Mice Increases Mechanisms of Emphysema Development: A Pilot Study.

Fischer K, Doehn JM, Herr C, Lachner C, Heinrich A, Kershaw O, Voss M, Jacobson MH, Gruber AD, Clauss M, Witzenrath M, Bals R, Gutbier B, Slevogt H.

Eur J Microbiol Immunol (Bp). 2018 Dec 11;8(4):128-134. doi: 10.1556/1886.2018.00019. eCollection 2018 Dec 23.


Contact Activation Inhibitor and Factor XI Antibody, AB023, Produces Safe, Dose-Dependent Anticoagulation in a Phase 1 First-In-Human Trial.

Lorentz CU, Verbout NG, Wallisch M, Hagen MW, Shatzel JJ, Olson SR, Puy C, Hinds MT, McCarty OJT, Gailani D, Gruber A, Tucker EI.

Arterioscler Thromb Vasc Biol. 2019 Apr;39(4):799-809. doi: 10.1161/ATVBAHA.118.312328.


Hepatic arterial infusion of irinotecan and EmboCept® S results in high tumor concentration of SN-38 in a rat model of colorectal liver metastases.

Kauffels A, Kitzmüller M, Gruber A, Nowack H, Bohnenberger H, Spitzner M, Kuthning A, Sprenger T, Czejka M, Ghadimi M, Sperling J.

Clin Exp Metastasis. 2019 Feb;36(1):57-66. doi: 10.1007/s10585-019-09954-5. Epub 2019 Jan 24.


Haemoproteus minutus is highly virulent for Australasian and South American parrots.

Ortiz-Catedral L, Brunton D, Stidworthy MF, Elsheikha HM, Pennycott T, Schulze C, Braun M, Wink M, Gerlach H, Pendl H, Gruber AD, Ewen J, Pérez-Tris J, Valkiūnas G, Olias P.

Parasit Vectors. 2019 Jan 17;12(1):40. doi: 10.1186/s13071-018-3255-0.


ADAR1 Is Required for Dendritic Cell Subset Homeostasis and Alveolar Macrophage Function.

Baal N, Cunningham S, Obermann HL, Thomas J, Lippitsch A, Dietert K, Gruber AD, Kaufmann A, Michel G, Nist A, Stiewe T, Rupp O, Goesmann A, Zukunft S, Fleming I, Bein G, Lohmeyer J, Bauer S, Hackstein H.

J Immunol. 2019 Feb 15;202(4):1099-1111. doi: 10.4049/jimmunol.1800269. Epub 2019 Jan 16.


A mechanism for hereditary angioedema with normal C1 inhibitor: an inhibitory regulatory role for the factor XII heavy chain.

Ivanov I, Matafonov A, Sun MF, Mohammed BM, Cheng Q, Dickeson SK, Kundu S, Verhamme IM, Gruber A, McCrae K, Gailani D.

Blood. 2019 Mar 7;133(10):1152-1163. doi: 10.1182/blood-2018-06-860270. Epub 2018 Dec 27.


Protease-activated receptor 4 activity promotes platelet granule release and platelet-leukocyte interactions.

Rigg RA, Healy LD, Chu TT, Ngo ATP, Mitrugno A, Zilberman-Rudenko J, Aslan JE, Hinds MT, Vecchiarelli LD, Morgan TK, Gruber A, Temple KJ, Lindsley CW, Duvernay MT, Hamm HE, McCarty OJT.

Platelets. 2019;30(1):126-135. doi: 10.1080/09537104.2017.1406076. Epub 2018 Dec 18.


Prevalence of Sarcocystis calchasi in free-ranging host species: Accipiter hawks and Common Woodpigeon in Germany.

Parmentier SL, Maier-Sam K, Failing K, Enderlein D, Gruber AD, Lierz M.

Sci Rep. 2018 Dec 4;8(1):17610. doi: 10.1038/s41598-018-35862-x.


Blasticidin-S deaminase, a new selection marker for genetic transformation of the diatom Phaeodactylum tricornutum.

Buck JM, Río Bártulos C, Gruber A, Kroth PG.

PeerJ. 2018 Nov 14;6:e5884. doi: 10.7717/peerj.5884. eCollection 2018.


Kinematics and shock attenuation during a prolonged run on the athletic track as measured with inertial magnetic measurement units.

Reenalda J, Maartens E, Buurke JH, Gruber AH.

Gait Posture. 2019 Feb;68:155-160. doi: 10.1016/j.gaitpost.2018.11.020. Epub 2018 Nov 19.


Increased risk of central nervous system tumours with carbamate insecticide use in the prospective cohort AGRICAN.

Piel C, Pouchieu C, Migault L, Béziat B, Boulanger M, Bureau M, Carles C, Grüber A, Lecluse Y, Rondeau V, Schwall X, Tual S, Lebailly P, Baldi I; AGRICAN group .

Int J Epidemiol. 2018 Nov 23. doi: 10.1093/ije/dyy246. [Epub ahead of print]


All-oral ixazomib, cyclophosphamide, and dexamethasone for transplant-ineligible patients with newly diagnosed multiple myeloma.

Dimopoulos MA, Grosicki S, Jędrzejczak WW, Nahi H, Gruber A, Hansson M, Gupta N, Byrne C, Labotka R, Teng Z, Yang H, Grzasko N, Kumar S.

Eur J Cancer. 2019 Jan;106:89-98. doi: 10.1016/j.ejca.2018.09.011. Epub 2018 Nov 22.


The role of coagulation and platelets in colon cancer-associated thrombosis.

Mitrugno A, Tassi Yunga S, Sylman JL, Zilberman-Rudenko J, Shirai T, Hebert JF, Kayton R, Zhang Y, Nan X, Shatzel JJ, Esener S, Duvernay MT, Hamm HE, Gruber A, Williams CD, Takata Y, Armstrong R, Morgan TK, McCarty OJT.

Am J Physiol Cell Physiol. 2019 Feb 1;316(2):C264-C273. doi: 10.1152/ajpcell.00367.2018. Epub 2018 Nov 21.


In-Host Adaptation of Salmonella enterica Serotype Dublin during Prosthetic Hip Joint Infection.

El Sayed F, Sapriel G, Fawal N, Gruber A, Bauer T, Heym B, Dupont C, Garchon HJ, Gaillard JL, Rottman M, Le Hello S.

Emerg Infect Dis. 2018 Dec;24(12):2360-2363. doi: 10.3201/eid2412.180214.


[Patients in the IDEAL cohort: A snapshot of severe asthma in France].

Taillé C, Pison C, Nocent C, Devouassoux G, Prud'homme A, Gruber A, Gunsoy N, Albers F.

Rev Mal Respir. 2019 Feb;36(2):179-190. doi: 10.1016/j.rmr.2018.10.005. Epub 2018 Nov 11. French.


Establishment of a Mucin Secreting Cell Line Cx-03 from an Uterine Carcino Sarcoma.

Bücker R, Schaefer C, Gruber AD, Hoppe J, Lazzerini L, Barinoff J, Sehouli J, Cichon G.

Pharm Res. 2018 Nov 8;36(1):7. doi: 10.1007/s11095-018-2533-z.


Lesions of lateral habenula attenuate win-stay but not lose-shift responses in a competitive choice task.

Thapa R, Donovan CH, Wong SA, Sutherland RJ, Gruber AJ.

Neurosci Lett. 2019 Jan 23;692:159-166. doi: 10.1016/j.neulet.2018.10.056. Epub 2018 Oct 31.


Delay in antibiotic therapy results in fatal disease outcome in murine pneumococcal pneumonia.

Berger S, Goekeri C, Gupta SK, Vera J, Dietert K, Behrendt U, Lienau J, Wienhold SM, Gruber AD, Suttorp N, Witzenrath M, Nouailles G.

Crit Care. 2018 Nov 1;22(1):287. doi: 10.1186/s13054-018-2224-5.


Ventilator-induced lung injury is aggravated by antibiotic mediated microbiota depletion in mice.

Wienhold SM, Macrì M, Nouailles G, Dietert K, Gurtner C, Gruber AD, Heimesaat MM, Lienau J, Schumacher F, Kleuser B, Opitz B, Suttorp N, Witzenrath M, Müller-Redetzky HC.

Crit Care. 2018 Oct 29;22(1):282. doi: 10.1186/s13054-018-2213-8.


Factor XII Activation Promotes Platelet Consumption in the Presence of Bacterial-Type Long-Chain Polyphosphate In Vitro and In Vivo.

Zilberman-Rudenko J, Reitsma SE, Puy C, Rigg RA, Smith SA, Tucker EI, Silasi R, Merkulova A, McCrae KR, Maas C, Urbanus RT, Gailani D, Morrissey JH, Gruber A, Lupu F, Schmaier AH, McCarty OJT.

Arterioscler Thromb Vasc Biol. 2018 Aug;38(8):1748-1760. doi: 10.1161/ATVBAHA.118.311193.


The Influence of Ankle Braces on Functional Performance Tests and Ankle Joint Range of Motion.

Mann B, Gruber AH, Murphy SP, Docherty CL.

J Sport Rehabil. 2019 Mar 3:1-7. doi: 10.1123/jsr.2018-0315. [Epub ahead of print]


Terminal exon characterization with TECtool reveals an abundance of cell-specific isoforms.

Gruber AJ, Gypas F, Riba A, Schmidt R, Zavolan M.

Nat Methods. 2018 Oct;15(10):832-836. doi: 10.1038/s41592-018-0114-z. Epub 2018 Sep 10.


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