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Items: 27

1.

Quantification of skeletal metastases in castrate-resistant prostate cancer predicts progression-free and overall survival.

Tait C, Moore D, Hodgson C, Brown M, Morris T, Growcott J, Malone M, Hughes A, Renehan A, Clarke NW, Dive C.

BJU Int. 2014 Dec;114(6b):E70-E73. doi: 10.1111/bju.12717. Epub 2014 Jul 27.

2.

A pilot study assessing the prognostic value of CK18 and nDNA biomarkers in severe sepsis patients.

Moore DJ, Greystoke A, Butt F, Wurthner J, Growcott J, Hughes A, Dive C.

Clin Drug Investig. 2012 Mar 1;32(3):179-87. doi: 10.2165/11598610-000000000-00000.

PMID:
22217154
3.

Role of the endothelin axis and its antagonists in the treatment of cancer.

Bagnato A, Loizidou M, Pflug BR, Curwen J, Growcott J.

Br J Pharmacol. 2011 May;163(2):220-33. doi: 10.1111/j.1476-5381.2011.01217.x. Review.

4.

AZD5438, a potent oral inhibitor of cyclin-dependent kinases 1, 2, and 9, leads to pharmacodynamic changes and potent antitumor effects in human tumor xenografts.

Byth KF, Thomas A, Hughes G, Forder C, McGregor A, Geh C, Oakes S, Green C, Walker M, Newcombe N, Green S, Growcott J, Barker A, Wilkinson RW.

Mol Cancer Ther. 2009 Jul;8(7):1856-66. doi: 10.1158/1535-7163.MCT-08-0836. Epub 2009 Jun 9.

5.

Epigenetic silencing of the endothelin-B receptor gene in non-small cell lung cancer.

Knight LJ, Burrage J, Bujac SR, Haggerty C, Graham A, Gibson NJ, Ellison G, Growcott JW, Brooks AN, Hughes AM, Xinarianos G, Nikolaidis G, Field JK, Liloglou T.

Int J Oncol. 2009 Feb;34(2):465-71.

PMID:
19148482
6.

Preclinical anticancer activity of the specific endothelin A receptor antagonist ZD4054.

Growcott JW.

Anticancer Drugs. 2009 Feb;20(2):83-8. doi: 10.1097/CAD.0b013e328320791c. Review.

PMID:
19065106
7.

Preclinical evaluation of M30 and M65 ELISAs as biomarkers of drug induced tumor cell death and antitumor activity.

Cummings J, Hodgkinson C, Odedra R, Sini P, Heaton SP, Mundt KE, Ward TH, Wilkinson RW, Growcott J, Hughes A, Dive C.

Mol Cancer Ther. 2008 Mar;7(3):455-63. doi: 10.1158/1535-7163.MCT-07-2136.

8.

A phase I pharmacodynamic study of the effects of the cyclin-dependent kinase-inhibitor AZD5438 on cell cycle markers within the buccal mucosa, plucked scalp hairs and peripheral blood mononucleocytes of healthy male volunteers.

Camidge DR, Pemberton M, Growcott J, Amakye D, Wilson D, Swaisland H, Forder C, Wilkinson R, Byth K, Hughes A.

Cancer Chemother Pharmacol. 2007 Sep;60(4):479-88. Epub 2006 Dec 2.

PMID:
17143601
9.

A first-in-man phase I tolerability and pharmacokinetic study of the cyclin-dependent kinase-inhibitor AZD5438 in healthy male volunteers.

Camidge DR, Smethurst D, Growcott J, Barrass NC, Foster JR, Febbraro S, Swaisland H, Hughes A.

Cancer Chemother Pharmacol. 2007 Aug;60(3):391-8. Epub 2006 Nov 18.

PMID:
17115157
10.

Assessing proliferation, cell-cycle arrest and apoptotic end points in human buccal punch biopsies for use as pharmacodynamic biomarkers in drug development.

Camidge DR, Pemberton MN, Growcott JW, Johnstone D, Laud PJ, Foster JR, Randall KJ, Hughes AM.

Br J Cancer. 2005 Jul 25;93(2):208-15.

11.

An investigation of components of variance and tachyphylaxis in a placebo-controlled intravenous tyramine study.

Cantarini MV, Watkins CL, Growcott J, Hughes AM.

Br J Clin Pharmacol. 2004 May;57(5):657-60.

12.

Body composition changes following laparoscopic gastric banding for morbid obesity.

Strauss BJ, Marks SJ, Growcott JP, Stroud DB, Lo CS, Dixon JB, O'Brien PE.

Acta Diabetol. 2003 Oct;40 Suppl 1:S266-9.

PMID:
14618490
13.

The prostaglandin E2 receptor-1 (EP-1) mediates acid-induced visceral pain hypersensitivity in humans.

Sarkar S, Hobson AR, Hughes A, Growcott J, Woolf CJ, Thompson DG, Aziz Q.

Gastroenterology. 2003 Jan;124(1):18-25.

PMID:
12512025
14.

Assessment of the reproducibility of intradermal administration of capsaicin as a model for inducing human pain.

Hughes A, Macleod A, Growcott J, Thomas I.

Pain. 2002 Sep;99(1-2):323-31.

PMID:
12237211
15.
16.

Sensitivity of repeated interdigital web pinching to detect antinociceptive effects of ibuprofen.

Growcott JW, Stone A, Beise R, Stammer H, Tetzloff W, Demey C.

Br J Clin Pharmacol. 2000 Apr;49(4):331-6.

17.

A comparison of the effects of aspirin on bleeding time measured using the Simplate method and closure time measured using the PFA-100, in healthy volunteers.

Marshall PW, Williams AJ, Dixon RM, Growcott JW, Warburton S, Armstrong J, Moores J.

Br J Clin Pharmacol. 1997 Aug;44(2):151-5.

18.

Zeneca ZD7114 acts as an antagonist at beta 3-adrenoceptors in rat isolated ileum.

Growcott JW, Holloway B, Green M, Wilson C.

Br J Pharmacol. 1993 Dec;110(4):1375-80.

19.
20.

Evaluation of ICI D7114, a putative stimulant of brown adipocytes, on histamine-contracted guinea-pig ileum.

Growcott JW, Wilson C, Holloway B, Mainwaring S.

Br J Pharmacol. 1993 Aug;109(4):1212-8.

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Further evidence for multiple tachykinin receptors.

Growcott JW, Jamieson A, Tarpey AV, Topham LD.

Eur J Pharmacol. 1982 Dec 17;86(1):59-64.

PMID:
6186499
24.

Effects of substance P-(1-9) nonapeptide amide on inactivation of substance P in vitro.

Growcott JW, Tarpey AV.

Eur J Pharmacol. 1982 Oct 15;84(1-2):107-9.

PMID:
6183129
25.

Effects of neonatal capsaicin administration on the nociceptive response of the rat to mechanical and chemical stimuli.

Faulkner DC, Growcott JW.

J Pharm Pharmacol. 1980 Sep;32(9):656-7. No abstract available.

PMID:
6107372
26.

Tachyphylaxis due to the D-Phe7 analogue of substance P.

Growcott JW, Petter NN.

J Pharm Pharmacol. 1980 May;32(5):376-7. No abstract available.

PMID:
6156233
27.

Failure of substance P to produce analgesia in the mouse [proceedings].

Growcott JW, Shaw JS.

Br J Pharmacol. 1979 May;66(1):129P. No abstract available.

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