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Effect of positron range on PET quantification in diseased and normal lungs.

Emond E, Groves AM, Hutton BF, Thielemans K.

Phys Med Biol. 2019 Sep 20. doi: 10.1088/1361-6560/ab469d. [Epub ahead of print]


Synergistic application of pulmonary 18F-FDG PET/HRCT and computer-based CT analysis with conventional severity measures to refine current risk stratification in idiopathic pulmonary fibrosis (IPF).

Fraioli F, Lyasheva M, Porter JC, Bomanji J, Shortman RI, Endozo R, Wan S, Bertoletti L, Machado M, Ganeshan B, Win T, Groves AM.

Eur J Nucl Med Mol Imaging. 2019 Sep;46(10):2023-2031. doi: 10.1007/s00259-019-04386-5. Epub 2019 Jul 8.


Diagnostic accuracy of whole-body MRI versus standard imaging pathways for metastatic disease in newly diagnosed non-small-cell lung cancer: the prospective Streamline L trial.

Taylor SA, Mallett S, Ball S, Beare S, Bhatnagar G, Bhowmik A, Boavida P, Bridgewater J, Clarke CS, Duggan M, Ellis S, Glynne-Jones R, Goh V, Groves AM, Hameeduddin A, Janes SM, Johnston EW, Koh DM, Lock S, Miles A, Morris S, Morton A, Navani N, Oliver A, O'Shaughnessy T, Padhani AR, Prezzi D, Punwani S, Quinn L, Rafiee H, Reczko K, Rockall AG, Russell P, Sidhu HS, Strickland N, Tarver K, Teague J, Halligan S; Streamline investigators.

Lancet Respir Med. 2019 Jun;7(6):523-532. doi: 10.1016/S2213-2600(19)30090-6. Epub 2019 May 9.


Diagnostic accuracy of whole-body MRI versus standard imaging pathways for metastatic disease in newly diagnosed colorectal cancer: the prospective Streamline C trial.

Taylor SA, Mallett S, Beare S, Bhatnagar G, Blunt D, Boavida P, Bridgewater J, Clarke CS, Duggan M, Ellis S, Glynne-Jones R, Goh V, Groves AM, Hameeduddin A, Janes SM, Johnston EW, Koh DM, Miles A, Morris S, Morton A, Navani N, O'Donohue J, Oliver A, Padhani AR, Pardoe H, Patel U, Punwani S, Quinn L, Rafiee H, Reczko K, Rockall AG, Shahabuddin K, Sidhu HS, Teague J, Thaha MA, Train M, van Ree K, Wijeyekoon S, Halligan S; Streamline investigators.

Lancet Gastroenterol Hepatol. 2019 Jul;4(7):529-537. doi: 10.1016/S2468-1253(19)30056-1. Epub 2019 May 9.


Apoptosis Resistance in Fibroblasts Precedes Progressive Scarring in Pulmonary Fibrosis and Is Partially Mediated by Toll-Like Receptor 4 Activation.

Hanson KM, Hernady EB, Reed CK, Johnston CJ, Groves AM, Finkelstein JN.

Toxicol Sci. 2019 Aug 1;170(2):489-498. doi: 10.1093/toxsci/kfz103.


Saving normal tissues - a goal for the ages.

Groves AM, Williams JP.

Int J Radiat Biol. 2019 Jul;95(7):920-935. doi: 10.1080/09553002.2019.1589654. Epub 2019 Mar 29.


A randomised, placebo-controlled study of omipalisib (PI3K/mTOR) in idiopathic pulmonary fibrosis.

Lukey PT, Harrison SA, Yang S, Man Y, Holman BF, Rashidnasab A, Azzopardi G, Grayer M, Simpson JK, Bareille P, Paul L, Woodcock HV, Toshner R, Saunders P, Molyneaux PL, Thielemans K, Wilson FJ, Mercer PF, Chambers RC, Groves AM, Fahy WA, Marshall RP, Maher TM.

Eur Respir J. 2019 Mar 18;53(3). pii: 1801992. doi: 10.1183/13993003.01992-2018. Print 2019 Mar.


Ventricular remodeling in preterm infants: computational cardiac magnetic resonance atlasing shows significant early remodeling of the left ventricle.

Cox DJ, Bai W, Price AN, Edwards AD, Rueckert D, Groves AM.

Pediatr Res. 2019 May;85(6):807-815. doi: 10.1038/s41390-018-0171-0. Epub 2018 Nov 19.


Magnetic Resonance Texture Analysis in Identifying Complete Pathological Response to Neoadjuvant Treatment in Locally Advanced Rectal Cancer.

Aker M, Ganeshan B, Afaq A, Wan S, Groves AM, Arulampalam T.

Dis Colon Rectum. 2019 Feb;62(2):163-170. doi: 10.1097/DCR.0000000000001224.


Modeling radiation-induced lung injury: lessons learned from whole thorax irradiation.

Beach TA, Groves AM, Williams JP, Finkelstein JN.

Int J Radiat Biol. 2018 Oct 25:1-16. doi: 10.1080/09553002.2018.1532619. [Epub ahead of print]


Recurrent DNA damage is associated with persistent injury in progressive radiation-induced pulmonary fibrosis.

Beach TA, Groves AM, Johnston CJ, Williams JP, Finkelstein JN.

Int J Radiat Biol. 2018 Dec;94(12):1104-1115. doi: 10.1080/09553002.2018.1516907. Epub 2018 Sep 21.


3D airway model to assess airway dead space.

Nieves A, Cozzo A, Kosoff Z, Traube C, Groves AM.

Arch Dis Child Fetal Neonatal Ed. 2019 May;104(3):F321-F323. doi: 10.1136/archdischild-2018-315621. Epub 2018 Sep 19.


A Potential Biomarker for Predicting the Risk of Radiation-Induced Fibrosis in the Lung.

Groves AM, Williams JP, Hernady E, Reed C, Fenton B, Love T, Finkelstein JN, Johnston CJ.

Radiat Res. 2018 Nov;190(5):513-525. doi: 10.1667/RR15122.1. Epub 2018 Aug 17.


Introduction to neonatologist-performed echocardiography.

Groves AM, Singh Y, Dempsey E, Molnar Z, Austin T, El-Khuffash A, de Boode WP; European Special Interest Group ‘Neonatologist Performed Echocardiography’ (NPE).

Pediatr Res. 2018 Jul;84(Suppl 1):1-12. doi: 10.1038/s41390-018-0076-y. Review.


Improved quantitation and reproducibility in multi-PET/CT lung studies by combining CT information.

Holman BF, Cuplov V, Millner L, Endozo R, Maher TM, Groves AM, Hutton BF, Thielemans K.

EJNMMI Phys. 2018 Jun 5;5(1):14. doi: 10.1186/s40658-018-0212-0.


Additional Clinical Value for PET/MRI in Oncology: Moving Beyond Simple Diagnosis.

Miles KA, Voo SA, Groves AM.

J Nucl Med. 2018 Jul;59(7):1028-1032. doi: 10.2967/jnumed.117.203612. Epub 2018 Mar 15. Review.


Pulmonary 18F-FDG uptake helps refine current risk stratification in idiopathic pulmonary fibrosis (IPF).

Win T, Screaton NJ, Porter JC, Ganeshan B, Maher TM, Fraioli F, Endozo R, Shortman RI, Hurrell L, Holman BF, Thielemans K, Rashidnasab A, Hutton BF, Lukey PT, Flynn A, Ell PJ, Groves AM.

Eur J Nucl Med Mol Imaging. 2018 May;45(5):806-815. doi: 10.1007/s00259-017-3917-8. Epub 2018 Jan 16.


Role of Infiltrating Monocytes in the Development of Radiation-Induced Pulmonary Fibrosis.

Groves AM, Johnston CJ, Williams JP, Finkelstein JN.

Radiat Res. 2018 Mar;189(3):300-311. doi: 10.1667/RR14874.1. Epub 2018 Jan 13.


Diagnostic accuracy and prognostic value of simultaneous hybrid 18F-fluorodeoxyglucose positron emission tomography/magnetic resonance imaging in cardiac sarcoidosis.

Wicks EC, Menezes LJ, Barnes A, Mohiddin SA, Sekhri N, Porter JC, Booth HL, Garrett E, Patel RS, Pavlou M, Groves AM, Elliott PM.

Eur Heart J Cardiovasc Imaging. 2018 Jul 1;19(7):757-767. doi: 10.1093/ehjci/jex340.


Effectiveness of echocardiography simulation training for paediatric cardiology fellows in CHD.

Dayton JD, Groves AM, Glickstein JS, Flynn PA.

Cardiol Young. 2018 Apr;28(4):611-615. doi: 10.1017/S104795111700275X. Epub 2018 Jan 8.


High-resolution rapid neonatal whole-body composition using 3.0 Tesla chemical shift magnetic resonance imaging.

Dyke JP, Garfinkel AC, Groves AM, Kovanlikaya A.

Pediatr Res. 2018 Mar;83(3):638-644. doi: 10.1038/pr.2017.294. Epub 2017 Dec 20.


Development of a PET/CT and PET/MRI patient information films in collaboration with patient representatives previously treated for cancer.

Shortman R, Hoath J, Osadolor T, Inga P, Roper L, Bomanji J, Groves AM.

J Nucl Med Technol. 2017 Oct 17. pii: jnmt.117.198770. doi: 10.2967/jnmt.117.198770. [Epub ahead of print]


Histologic and biochemical alterations predict pulmonary mechanical dysfunction in aging mice with chronic lung inflammation.

Massa CB, Groves AM, Jaggernauth SU, Laskin DL, Gow AJ.

PLoS Comput Biol. 2017 Aug 24;13(8):e1005570. doi: 10.1371/journal.pcbi.1005570. eCollection 2017 Aug.


Radiation induced pulmonary fibrosis as a model of progressive fibrosis: Contributions of DNA damage, inflammatory response and cellular senescence genes.

Beach TA, Johnston CJ, Groves AM, Williams JP, Finkelstein JN.

Exp Lung Res. 2017 Apr;43(3):134-149. doi: 10.1080/01902148.2017.1318975. Epub 2017 May 23.


Streamlining staging of lung and colorectal cancer with whole body MRI; study protocols for two multicentre, non-randomised, single-arm, prospective diagnostic accuracy studies (Streamline C and Streamline L).

Taylor SA, Mallett S, Miles A, Beare S, Bhatnagar G, Bridgewater J, Glynne-Jones R, Goh V, Groves AM, Janes SM, Koh DM, Morris S, Morton A, Navani N, Oliver A, Padhani AR, Punwani S, Rockall AG, Halligan S.

BMC Cancer. 2017 May 2;17(1):299. doi: 10.1186/s12885-017-3281-x.


Detection of Atherosclerotic Inflammation by 68Ga-DOTATATE PET Compared to [18F]FDG PET Imaging.

Tarkin JM, Joshi FR, Evans NR, Chowdhury MM, Figg NL, Shah AV, Starks LT, Martin-Garrido A, Manavaki R, Yu E, Kuc RE, Grassi L, Kreuzhuber R, Kostadima MA, Frontini M, Kirkpatrick PJ, Coughlin PA, Gopalan D, Fryer TD, Buscombe JR, Groves AM, Ouwehand WH, Bennett MR, Warburton EA, Davenport AP, Rudd JH.

J Am Coll Cardiol. 2017 Apr 11;69(14):1774-1791. doi: 10.1016/j.jacc.2017.01.060.


Quantification of Lung PET Images: Challenges and Opportunities.

Chen DL, Cheriyan J, Chilvers ER, Choudhury G, Coello C, Connell M, Fisk M, Groves AM, Gunn RN, Holman BF, Hutton BF, Lee S, MacNee W, Mohan D, Parr D, Subramanian D, Tal-Singer R, Thielemans K, van Beek EJ, Vass L, Wellen JW, Wilkinson I, Wilson FJ.

J Nucl Med. 2017 Feb;58(2):201-207. doi: 10.2967/jnumed.116.184796. Epub 2017 Jan 12. Review.


Accuracy and cost-effectiveness of dynamic contrast-enhanced CT in the characterisation of solitary pulmonary nodules-the SPUtNIk study.

Qureshi NR, Rintoul RC, Miles KA, George S, Harris S, Madden J, Cozens K, Little LA, Eichhorst K, Jones J, Moate P, McClement C, Pike L, Sinclair D, Wong WL, Shekhdar J, Eaton R, Shah A, Brindle L, Peebles C, Banerjee A, Dizdarevic S, Han S, Poon FW, Groves AM, Kurban L, Frew AJ, Callister ME, Crosbie P, Gleeson FV, Karunasaagarar K, Kankam O, Gilbert FJ.

BMJ Open Respir Res. 2016 Oct 14;3(1):e000156. eCollection 2016.


Editor's Highlight: CCR2 Regulates Inflammatory Cell Accumulation in the Lung and Tissue Injury following Ozone Exposure.

Francis M, Groves AM, Sun R, Cervelli JA, Choi H, Laskin JD, Laskin DL.

Toxicol Sci. 2017 Feb;155(2):474-484. doi: 10.1093/toxsci/kfw226. Epub 2016 Nov 11.


Imaging biomarker roadmap for cancer studies.

O'Connor JP, Aboagye EO, Adams JE, Aerts HJ, Barrington SF, Beer AJ, Boellaard R, Bohndiek SE, Brady M, Brown G, Buckley DL, Chenevert TL, Clarke LP, Collette S, Cook GJ, deSouza NM, Dickson JC, Dive C, Evelhoch JL, Faivre-Finn C, Gallagher FA, Gilbert FJ, Gillies RJ, Goh V, Griffiths JR, Groves AM, Halligan S, Harris AL, Hawkes DJ, Hoekstra OS, Huang EP, Hutton BF, Jackson EF, Jayson GC, Jones A, Koh DM, Lacombe D, Lambin P, Lassau N, Leach MO, Lee TY, Leen EL, Lewis JS, Liu Y, Lythgoe MF, Manoharan P, Maxwell RJ, Miles KA, Morgan B, Morris S, Ng T, Padhani AR, Parker GJ, Partridge M, Pathak AP, Peet AC, Punwani S, Reynolds AR, Robinson SP, Shankar LK, Sharma RA, Soloviev D, Stroobants S, Sullivan DC, Taylor SA, Tofts PS, Tozer GM, van Herk M, Walker-Samuel S, Wason J, Williams KJ, Workman P, Yankeelov TE, Brindle KM, McShane LM, Jackson A, Waterton JC.

Nat Rev Clin Oncol. 2017 Mar;14(3):169-186. doi: 10.1038/nrclinonc.2016.162. Epub 2016 Oct 11. Review.


"Textural analysis of multiparametric MRI detects transition zone prostate cancer".

Sidhu HS, Benigno S, Ganeshan B, Dikaios N, Johnston EW, Allen C, Kirkham A, Groves AM, Ahmed HU, Emberton M, Taylor SA, Halligan S, Punwani S.

Eur Radiol. 2017 Jun;27(6):2348-2358. doi: 10.1007/s00330-016-4579-9. Epub 2016 Sep 12.


Effects of IL-4 on pulmonary fibrosis and the accumulation and phenotype of macrophage subpopulations following thoracic irradiation.

Groves AM, Johnston CJ, Misra RS, Williams JP, Finkelstein JN.

Int J Radiat Biol. 2016 Dec;92(12):754-765. Epub 2016 Sep 15.


CT-based texture analysis potentially provides prognostic information complementary to interim fdg-pet for patients with hodgkin's and aggressive non-hodgkin's lymphomas.

Ganeshan B, Miles KA, Babikir S, Shortman R, Afaq A, Ardeshna KM, Groves AM, Kayani I.

Eur Radiol. 2017 Mar;27(3):1012-1020. doi: 10.1007/s00330-016-4470-8. Epub 2016 Jul 5.


A modified echocardiographic approach improves reliability of superior vena caval flow quantification.

Ficial B, Bonafiglia E, Padovani EM, Prioli MA, Finnemore AE, Cox DJ, Broadhouse KM, Price AN, Durighel G, Groves AM.

Arch Dis Child Fetal Neonatal Ed. 2017 Jan;102(1):F7-F11. doi: 10.1136/archdischild-2015-309523. Epub 2016 May 26.


Cerebral metabolism and perfusion in MR-negative individuals with refractory focal epilepsy assessed by simultaneous acquisition of (18)F-FDG PET and arterial spin labeling.

Boscolo Galazzo I, Mattoli MV, Pizzini FB, De Vita E, Barnes A, Duncan JS, Jäger HR, Golay X, Bomanji JB, Koepp M, Groves AM, Fraioli F.

Neuroimage Clin. 2016 Apr 12;11:648-657. doi: 10.1016/j.nicl.2016.04.005. eCollection 2016.


The effect of respiratory induced density variations on non-TOF PET quantitation in the lung.

Holman BF, Cuplov V, Hutton BF, Groves AM, Thielemans K.

Phys Med Biol. 2016 Apr 21;61(8):3148-63. doi: 10.1088/0031-9155/61/8/3148. Epub 2016 Mar 23.


Positive (18)Fluorodeoxyglucose-Positron Emission Tomography/Computed Tomography Predicts Preinvasive Endobronchial Lesion Progression to Invasive Cancer.

Fraioli F, Kayani I, Smith LJ, Bomanji JB, Capitanio A, Falzon M, Carroll B, Navani N, Brown J, Thakrar RM, George PJ, Groves AM, Janes SM.

Am J Respir Crit Care Med. 2016 Mar 1;193(5):576-9. doi: 10.1164/rccm.201508-1617LE. No abstract available.


Whole-Lung Irradiation Results in Pulmonary Macrophage Alterations that are Subpopulation and Strain Specific.

Groves AM, Johnston CJ, Misra RS, Williams JP, Finkelstein JN.

Radiat Res. 2015 Dec;184(6):639-49. doi: 10.1667/RR14178.1. Epub 2015 Dec 3.


Multicenter Reproducibility of 18F-Fluciclatide PET Imaging in Subjects with Solid Tumors.

Sharma R, Kallur KG, Ryu JS, Parameswaran RV, Lindman H, Avril N, Gleeson FV, Lee JD, Lee KH, O'Doherty MJ, Groves AM, Miller MP, Somer EJ, Coombes CR, Aboagye EO.

J Nucl Med. 2015 Dec;56(12):1855-61. doi: 10.2967/jnumed.115.158253. Epub 2015 Sep 17.


Expert consensus statement 'Neonatologist-performed Echocardiography (NoPE)'-training and accreditation in UK.

Singh Y, Gupta S, Groves AM, Gandhi A, Thomson J, Qureshi S, Simpson JM.

Eur J Pediatr. 2016 Feb;175(2):281-7. doi: 10.1007/s00431-015-2633-2. Epub 2015 Sep 12.


Improved correction for the tissue fraction effect in lung PET/CT imaging.

Holman BF, Cuplov V, Millner L, Hutton BF, Maher TM, Groves AM, Thielemans K.

Phys Med Biol. 2015 Sep 21;60(18):7387-402. doi: 10.1088/0031-9155/60/18/7387. Epub 2015 Sep 9.


Examining the Effects of External or Internal Radiation Exposure of Juvenile Mice on Late Morbidity after Infection with Influenza A.

Misra RS, Johnston CJ, Groves AM, DeDiego ML, St Martin J, Reed C, Hernady E, Miller JN, Love T, Finkelstein JN, Williams JP.

Radiat Res. 2015 Jul;184(1):3-13. Epub 2015 Jun 26.


A comparison of the psychological burden of PET/MRI and PET/CT scans and association to initial state anxiety and previous imaging experiences.

Shortman RI, Neriman D, Hoath J, Millner L, Endozo R, Azzopardi G, O'Meara C, Bomanji J, Groves AM.

Br J Radiol. 2015 Aug;88(1052):20150121. doi: 10.1259/bjr.20150121. Epub 2015 Jun 19.


Predicting Aortic Aneurysm Expansion by PET.

Rudd JH, Coughlin PA, Groves AM.

J Nucl Med. 2015 Jul;56(7):971-3. doi: 10.2967/jnumed.115.154062. Epub 2015 Apr 23. No abstract available.


Decreasing mean airway pressure as a management strategy for tension pneumatocoeles.

Wellington AC, Spigland NA, Worgall S, Groves AM.

Arch Dis Child Fetal Neonatal Ed. 2015 Mar;100(2):F101. doi: 10.1136/archdischild-2014-307405. Epub 2014 Nov 13. No abstract available.


18F-fluoroethylcholine (18F-Cho) PET/MRI functional parameters in pediatric astrocytic brain tumors.

Fraioli F, Shankar A, Hargrave D, Hyare H, Gaze MN, Groves AM, Alongi P, Stoneham S, Michopoulou S, Syed R, Bomanji JB.

Clin Nucl Med. 2015 Jan;40(1):e40-5. doi: 10.1097/RLU.0000000000000556.


Cardiovascular magnetic resonance of cardiac function and myocardial mass in preterm infants: a preliminary study of the impact of patent ductus arteriosus.

Broadhouse KM, Finnemore AE, Price AN, Durighel G, Cox DJ, Edwards AD, Hajnal JV, Groves AM.

J Cardiovasc Magn Reson. 2014 Jul 23;16:54. doi: 10.1186/s12968-014-0054-4.


Non-small-cell lung cancer resectability: diagnostic value of PET/MR.

Fraioli F, Screaton NJ, Janes SM, Win T, Menezes L, Kayani I, Syed R, Zaccagna F, O'Meara C, Barnes A, Bomanji JB, Punwani S, Groves AM.

Eur J Nucl Med Mol Imaging. 2015 Jan;42(1):49-55. doi: 10.1007/s00259-014-2873-9. Epub 2014 Aug 15.


Superior vena flow quantification in the newborn: reply to a letter by Kluckow and Evans.

Ficial B, Groves AM.

J Am Soc Echocardiogr. 2014 Jul;27(7):794-6. doi: 10.1016/j.echo.2014.05.004. No abstract available.


Correlation of intra-tumor 18F-FDG uptake heterogeneity indices with perfusion CT derived parameters in colorectal cancer.

Tixier F, Groves AM, Goh V, Hatt M, Ingrand P, Le Rest CC, Visvikis D.

PLoS One. 2014 Jun 13;9(6):e99567. doi: 10.1371/journal.pone.0099567. eCollection 2014.

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