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Items: 1 to 50 of 139

1.

Reelin is modulated by diet-induced obesity and has direct actions on arcuate proopiomelanocortin neurons.

Roberts BL, Bennett BJ, Bennett CM, Carroll JM, Dalbøge LS, Hall C, Hassouneh W, Heppner KM, Kirigiti MA, Lindsley SR, Tennant KG, True CA, Whittle A, Wolf AC, Roberts CT Jr, Tang-Christensen M, Sleeman MW, Cowley MA, Grove KL, Kievit P.

Mol Metab. 2019 Aug;26:18-29. doi: 10.1016/j.molmet.2019.06.001. Epub 2019 Jun 8.

2.

The central fibroblast growth factor receptor/beta klotho system: Comprehensive mapping in Mus musculus and comparisons to nonhuman primate and human samples using an automated in situ hybridization platform.

Hultman K, Scarlett JM, Baquero AF, Cornea A, Zhang Y, Salinas CBG, Brown J, Morton GJ, Whalen EJ, Grove KL, Koegler FH, Schwartz MW, Mercer AJ.

J Comp Neurol. 2019 Aug 15;527(12):2069-2085. doi: 10.1002/cne.24668. Epub 2019 Mar 9.

PMID:
30809795
3.

Determining the Effects of Combined Liraglutide and Phentermine on Metabolic Parameters, Blood Pressure, and Heart Rate in Lean and Obese Male Mice.

Simonds SE, Pryor JT, Koegler FH, Buch-Rasmussen AS, Kelly LE, Grove KL, Cowley MA.

Diabetes. 2019 Apr;68(4):683-695. doi: 10.2337/db18-1149. Epub 2019 Jan 23.

4.

Maternal high-fat diet reversal improves placental hemodynamics in a nonhuman primate model of diet-induced obesity.

Salati JA, Roberts VHJ, Schabel MC, Lo JO, Kroenke CD, Lewandowski KS, Lindner JR, Grove KL, Frias AE.

Int J Obes (Lond). 2019 Apr;43(4):906-916. doi: 10.1038/s41366-018-0145-7. Epub 2018 Jul 13.

5.

FGF21 decreases body weight without reducing food intake or bone mineral density in high-fat fed obese rhesus macaque monkeys.

Andersen B, Straarup EM, Heppner KM, Takahashi DL, Raffaele V, Dissen GA, Lewandowski K, Bödvarsdottir TB, Raun K, Grove KL, Kievit P.

Int J Obes (Lond). 2018 Jun;42(6):1151-1160. doi: 10.1038/s41366-018-0080-7. Epub 2018 Jun 11.

6.

Arcuate nucleus neuropeptide coexpression and connections to gonadotrophin-releasing hormone neurones in the female rhesus macaque.

True C, Takahashi D, Kirigiti M, Lindsley SR, Moctezuma C, Arik A, Smith MS, Kievit P, Grove KL.

J Neuroendocrinol. 2017 Jun;29(6). doi: 10.1111/jne.12491.

7.

Adverse Placental Perfusion and Pregnancy Outcomes in a New Nonhuman Primate Model of Gestational Protein Restriction.

Roberts VHJ, Lo JO, Lewandowski KS, Blundell P, Grove KL, Kroenke CD, Sullivan EL, Roberts CT Jr, Frias AE.

Reprod Sci. 2018 Jan;25(1):110-119. doi: 10.1177/1933719117704907. Epub 2017 Apr 26.

8.

Maternal and postnatal high-fat diet consumption programs energy balance and hypothalamic melanocortin signaling in nonhuman primate offspring.

Sullivan EL, Rivera HM, True CA, Franco JG, Baquero K, Dean TA, Valleau JC, Takahashi DL, Frazee T, Hanna G, Kirigiti MA, Bauman LA, Grove KL, Kievit P.

Am J Physiol Regul Integr Comp Physiol. 2017 Aug 1;313(2):R169-R179. doi: 10.1152/ajpregu.00309.2016. Epub 2017 Apr 12.

9.

GLP-1R Signaling Directly Activates Arcuate Nucleus Kisspeptin Action in Brain Slices but Does not Rescue Luteinizing Hormone Inhibition in Ovariectomized Mice During Negative Energy Balance.

Heppner KM, Baquero AF, Bennett CM, Lindsley SR, Kirigiti MA, Bennett B, Bosch MA, Mercer AJ, Rønnekleiv OK, True C, Grove KL, Smith MS.

eNeuro. 2017 Jan 20;4(1). pii: ENEURO.0198-16.2016. doi: 10.1523/ENEURO.0198-16.2016. eCollection 2017 Jan-Feb.

10.

Genomic Variants Associated with Resistance to High Fat Diet Induced Obesity in a Primate Model.

Harris RA, Alcott CE, Sullivan EL, Takahashi D, McCurdy CE, Comstock S, Baquero K, Blundell P, Frias AE, Kahr M, Suter M, Wesolowski S, Friedman JE, Grove KL, Aagaard KM.

Sci Rep. 2016 Nov 4;6:36123. doi: 10.1038/srep36123.

11.

Maternal obesity reduces oxidative capacity in fetal skeletal muscle of Japanese macaques.

McCurdy CE, Schenk S, Hetrick B, Houck J, Drew BG, Kaye S, Lashbrook M, Bergman BC, Takahashi DL, Dean TA, Nemkov T, Gertsman I, Hansen KC, Philp A, Hevener AL, Chicco AJ, Aagaard KM, Grove KL, Friedman JE.

JCI Insight. 2016 Oct 6;1(16):e86612. doi: 10.1172/jci.insight.86612.

12.

α-Melanocyte stimulating hormone promotes muscle glucose uptake via melanocortin 5 receptors.

Enriori PJ, Chen W, Garcia-Rudaz MC, Grayson BE, Evans AE, Comstock SM, Gebhardt U, Müller HL, Reinehr T, Henry BA, Brown RD, Bruce CR, Simonds SE, Litwak SA, McGee SL, Luquet S, Martinez S, Jastroch M, Tschöp MH, Watt MJ, Clarke IJ, Roth CL, Grove KL, Cowley MA.

Mol Metab. 2016 Aug 5;5(10):807-822. doi: 10.1016/j.molmet.2016.07.009. eCollection 2016 Oct.

13.

Vasoconstrictor eicosanoids and impaired microvascular function in inactive and insulin-resistant primates.

Chadderdon SM, Belcik JT, Bader L, Kievit P, Grove KL, Lindner JR.

Int J Obes (Lond). 2016 Oct;40(10):1600-1603. doi: 10.1038/ijo.2016.117. Epub 2016 Jun 30.

14.

Temporal Changes in Skeletal Muscle Capillary Responses and Endothelial-Derived Vasodilators in Obesity-Related Insulin Resistance.

Chadderdon SM, Belcik JT, Bader L, Peters DM, Kievit P, Alkayed NJ, Kaul S, Grove KL, Lindner JR.

Diabetes. 2016 Aug;65(8):2249-57. doi: 10.2337/db15-1574. Epub 2016 Apr 8.

15.

Postnatal undernutrition delays a key step in the maturation of hypothalamic feeding circuits.

Juan De Solis A, Baquero AF, Bennett CM, Grove KL, Zeltser LM.

Mol Metab. 2016 Jan 15;5(3):198-209. doi: 10.1016/j.molmet.2016.01.003. eCollection 2016 Mar.

16.

The MAFB transcription factor impacts islet α-cell function in rodents and represents a unique signature of primate islet β-cells.

Conrad E, Dai C, Spaeth J, Guo M, Cyphert HA, Scoville D, Carroll J, Yu WM, Goodrich LV, Harlan DM, Grove KL, Roberts CT Jr, Powers AC, Gu G, Stein R.

Am J Physiol Endocrinol Metab. 2016 Jan 1;310(1):E91-E102. doi: 10.1152/ajpendo.00285.2015. Epub 2015 Nov 10.

17.

Maternal high-fat diet and obesity impact palatable food intake and dopamine signaling in nonhuman primate offspring.

Rivera HM, Kievit P, Kirigiti MA, Bauman LA, Baquero K, Blundell P, Dean TA, Valleau JC, Takahashi DL, Frazee T, Douville L, Majer J, Smith MS, Grove KL, Sullivan EL.

Obesity (Silver Spring). 2015 Nov;23(11):2157-64. doi: 10.1002/oby.21306.

18.

Melanocortin agonists stimulate lipolysis in human adipose tissue explants but not in adipocytes.

Møller CL, Pedersen SB, Richelsen B, Conde-Frieboes KW, Raun K, Grove KL, Wulff BS.

BMC Res Notes. 2015 Oct 12;8:559. doi: 10.1186/s13104-015-1539-4.

19.

Urocortin3 mediates somatostatin-dependent negative feedback control of insulin secretion.

van der Meulen T, Donaldson CJ, Cáceres E, Hunter AE, Cowing-Zitron C, Pound LD, Adams MW, Zembrzycki A, Grove KL, Huising MO.

Nat Med. 2015 Jul;21(7):769-76. doi: 10.1038/nm.3872. Epub 2015 Jun 15.

20.

Developmental changes in synaptic distribution in arcuate nucleus neurons.

Baquero AF, Kirigiti MA, Baquero KC, Lee SJ, Smith MS, Grove KL.

J Neurosci. 2015 Jun 3;35(22):8558-69. doi: 10.1523/JNEUROSCI.0058-15.2015.

21.

Impact of maternal obesity on fetal programming of cardiovascular disease.

Roberts VH, Frias AE, Grove KL.

Physiology (Bethesda). 2015 May;30(3):224-31. doi: 10.1152/physiol.00021.2014. Review.

22.

Peroxisome proliferator-activated receptor γ controls ingestive behavior, agouti-related protein, and neuropeptide Y mRNA in the arcuate hypothalamus.

Garretson JT, Teubner BJ, Grove KL, Vazdarjanova A, Ryu V, Bartness TJ.

J Neurosci. 2015 Mar 18;35(11):4571-81. doi: 10.1523/JNEUROSCI.2129-14.2015.

23.

Gadolinium Chelate Contrast Material in Pregnancy: Fetal Biodistribution in the Nonhuman Primate.

Oh KY, Roberts VH, Schabel MC, Grove KL, Woods M, Frias AE.

Radiology. 2015 Jul;276(1):110-8. doi: 10.1148/radiol.15141488. Epub 2015 Mar 11.

24.

Leptin mediates the increase in blood pressure associated with obesity.

Simonds SE, Pryor JT, Ravussin E, Greenway FL, Dileone R, Allen AM, Bassi J, Elmquist JK, Keogh JM, Henning E, Myers MG Jr, Licinio J, Brown RD, Enriori PJ, O'Rahilly S, Sternson SM, Grove KL, Spanswick DC, Farooqi IS, Cowley MA.

Cell. 2014 Dec 4;159(6):1404-16. doi: 10.1016/j.cell.2014.10.058.

25.

Expression and distribution of glucagon-like peptide-1 receptor mRNA, protein and binding in the male nonhuman primate (Macaca mulatta) brain.

Heppner KM, Kirigiti M, Secher A, Paulsen SJ, Buckingham R, Pyke C, Knudsen LB, Vrang N, Grove KL.

Endocrinology. 2015 Jan;156(1):255-67. doi: 10.1210/en.2014-1675.

26.

Brain insulin lowers circulating BCAA levels by inducing hepatic BCAA catabolism.

Shin AC, Fasshauer M, Filatova N, Grundell LA, Zielinski E, Zhou JY, Scherer T, Lindtner C, White PJ, Lapworth AL, Ilkayeva O, Knippschild U, Wolf AM, Scheja L, Grove KL, Smith RD, Qian WJ, Lynch CJ, Newgard CB, Buettner C.

Cell Metab. 2014 Nov 4;20(5):898-909. doi: 10.1016/j.cmet.2014.09.003. Epub 2014 Oct 9.

27.

The arcuate nucleus mediates GLP-1 receptor agonist liraglutide-dependent weight loss.

Secher A, Jelsing J, Baquero AF, Hecksher-Sørensen J, Cowley MA, Dalbøge LS, Hansen G, Grove KL, Pyke C, Raun K, Schäffer L, Tang-Christensen M, Verma S, Witgen BM, Vrang N, Bjerre Knudsen L.

J Clin Invest. 2014 Oct;124(10):4473-88. doi: 10.1172/JCI75276. Epub 2014 Sep 9.

28.

Developmental switch of leptin signaling in arcuate nucleus neurons.

Baquero AF, de Solis AJ, Lindsley SR, Kirigiti MA, Smith MS, Cowley MA, Zeltser LM, Grove KL.

J Neurosci. 2014 Jul 23;34(30):9982-94. doi: 10.1523/JNEUROSCI.0933-14.2014.

29.

Endogenous kisspeptin tone is a critical excitatory component of spontaneous GnRH activity and the GnRH response to NPY and CART.

Verma S, Kirigiti MA, Millar RP, Grove KL, Smith MS.

Neuroendocrinology. 2014;99(3-4):190-203. doi: 10.1159/000365419. Epub 2014 Jul 7.

30.

High-fat maternal diet during pregnancy persistently alters the offspring microbiome in a primate model.

Ma J, Prince AL, Bader D, Hu M, Ganu R, Baquero K, Blundell P, Alan Harris R, Frias AE, Grove KL, Aagaard KM.

Nat Commun. 2014 May 20;5:3889. doi: 10.1038/ncomms4889.

31.

Consumption of a Western-style diet during pregnancy impairs offspring islet vascularization in a Japanese macaque model.

Pound LD, Comstock SM, Grove KL.

Am J Physiol Endocrinol Metab. 2014 Jul 1;307(1):E115-23. doi: 10.1152/ajpendo.00131.2014. Epub 2014 May 20.

32.

Early life exposure to maternal insulin resistance has persistent effects on hepatic NAFLD in juvenile nonhuman primates.

Thorn SR, Baquero KC, Newsom SA, El Kasmi KC, Bergman BC, Shulman GI, Grove KL, Friedman JE.

Diabetes. 2014 Aug;63(8):2702-13. doi: 10.2337/db14-0276. Epub 2014 Apr 4.

33.

The nonhuman primate as a model for type 2 diabetes.

Pound LD, Kievit P, Grove KL.

Curr Opin Endocrinol Diabetes Obes. 2014 Apr;21(2):89-94. doi: 10.1097/MED.0000000000000043. Review.

PMID:
24569549
34.

Beneficial and cautionary outcomes of resveratrol supplementation in pregnant nonhuman primates.

Roberts VH, Pound LD, Thorn SR, Gillingham MB, Thornburg KL, Friedman JE, Frias AE, Grove KL.

FASEB J. 2014 Jun;28(6):2466-77. doi: 10.1096/fj.13-245472. Epub 2014 Feb 21.

35.

Proinflammatory endothelial activation detected by molecular imaging in obese nonhuman primates coincides with onset of insulin resistance and progressively increases with duration of insulin resistance.

Chadderdon SM, Belcik JT, Bader L, Kirigiti MA, Peters DM, Kievit P, Grove KL, Lindner JR.

Circulation. 2014 Jan 28;129(4):471-8. doi: 10.1161/CIRCULATIONAHA.113.003645. Epub 2013 Oct 25.

36.

Targeting oxidized LDL improves insulin sensitivity and immune cell function in obese Rhesus macaques.

Li S, Kievit P, Robertson AK, Kolumam G, Li X, von Wachenfeldt K, Valfridsson C, Bullens S, Messaoudi I, Bader L, Cowan KJ, Kamath A, van Bruggen N, Bunting S, Frendéus B, Grove KL.

Mol Metab. 2013 Jun 11;2(3):256-69. doi: 10.1016/j.molmet.2013.06.001. eCollection 2013.

37.

Leptin stimulates neuropeptide Y and cocaine amphetamine-regulated transcript coexpressing neuronal activity in the dorsomedial hypothalamus in diet-induced obese mice.

Lee SJ, Verma S, Simonds SE, Kirigiti MA, Kievit P, Lindsley SR, Loche A, Smith MS, Cowley MA, Grove KL.

J Neurosci. 2013 Sep 18;33(38):15306-17. doi: 10.1523/JNEUROSCI.0837-13.2013.

38.

Neonatal overnutrition in mice exacerbates high-fat diet-induced metabolic perturbations.

Liu Z, Lim CY, Su MY, Soh SL, Shui G, Wenk MR, Grove KL, Radda GK, Han W, Xiao X.

J Endocrinol. 2013 Oct 4;219(2):131-43. doi: 10.1530/JOE-13-0111. Print 2013 Nov.

PMID:
23959078
39.

Postweaning exposure to a high-fat diet is associated with alterations to the hepatic histone code in Japanese macaques.

Suter MA, Takahashi D, Grove KL, Aagaard KM.

Pediatr Res. 2013 Sep;74(3):252-8. doi: 10.1038/pr.2013.106. Epub 2013 Jun 20.

40.

Increased fibroblast growth factor 21 expression in high-fat diet-sensitive non-human primates (Macaca mulatta).

Nygaard EB, Møller CL, Kievit P, Grove KL, Andersen B.

Int J Obes (Lond). 2014 Feb;38(2):183-91. doi: 10.1038/ijo.2013.79. Epub 2013 May 21.

41.
42.

Pancreatic inflammation and increased islet macrophages in insulin-resistant juvenile primates.

Nicol LE, Grant WF, Comstock SM, Nguyen ML, Smith MS, Grove KL, Marks DL.

J Endocrinol. 2013 Apr 15;217(2):207-13. doi: 10.1530/JOE-12-0424. Print 2013 May. Erratum in: J Endocrinol. 2013 Jul;218(1):X1. Grant, W R [corrected to Grant, W F].

43.

Efferent projections of neuropeptide Y-expressing neurons of the dorsomedial hypothalamus in chronic hyperphagic models.

Lee SJ, Kirigiti M, Lindsley SR, Loche A, Madden CJ, Morrison SF, Smith MS, Grove KL.

J Comp Neurol. 2013 Jun 1;521(8):1891-914. doi: 10.1002/cne.23265.

44.

Perinatal exposure to a high-fat diet is associated with reduced hepatic sympathetic innervation in one-year old male Japanese macaques.

Grant WF, Nicol LE, Thorn SR, Grove KL, Friedman JE, Marks DL.

PLoS One. 2012;7(10):e48119. doi: 10.1371/journal.pone.0048119. Epub 2012 Oct 30.

45.

Obesity: a transgenerational problem linked to nutrition during pregnancy.

Frias AE, Grove KL.

Semin Reprod Med. 2012 Dec;30(6):472-8. doi: 10.1055/s-0032-1328875. Epub 2012 Oct 16. Review.

46.

Chronic treatment with a melanocortin-4 receptor agonist causes weight loss, reduces insulin resistance, and improves cardiovascular function in diet-induced obese rhesus macaques.

Kievit P, Halem H, Marks DL, Dong JZ, Glavas MM, Sinnayah P, Pranger L, Cowley MA, Grove KL, Culler MD.

Diabetes. 2013 Feb;62(2):490-7. doi: 10.2337/db12-0598. Epub 2012 Oct 9.

47.

Maternal high-fat diet modulates the fetal thyroid axis and thyroid gene expression in a nonhuman primate model.

Suter MA, Sangi-Haghpeykar H, Showalter L, Shope C, Hu M, Brown K, Williams S, Harris RA, Grove KL, Lane RH, Aagaard KM.

Mol Endocrinol. 2012 Dec;26(12):2071-80. doi: 10.1210/me.2012-1214. Epub 2012 Sep 26.

48.

A maternal high-fat diet modulates fetal SIRT1 histone and protein deacetylase activity in nonhuman primates.

Suter MA, Chen A, Burdine MS, Choudhury M, Harris RA, Lane RH, Friedman JE, Grove KL, Tackett AJ, Aagaard KM.

FASEB J. 2012 Dec;26(12):5106-14. doi: 10.1096/fj.12-212878. Epub 2012 Sep 14.

49.

Activity restriction, impaired capillary function, and the development of insulin resistance in lean primates.

Chadderdon SM, Belcik JT, Smith E, Pranger L, Kievit P, Grove KL, Lindner JR.

Am J Physiol Endocrinol Metab. 2012 Sep 1;303(5):E607-13. doi: 10.1152/ajpendo.00231.2012. Epub 2012 Jun 26.

50.

Maternal high-fat diet impacts endothelial function in nonhuman primate offspring.

Fan L, Lindsley SR, Comstock SM, Takahashi DL, Evans AE, He GW, Thornburg KL, Grove KL.

Int J Obes (Lond). 2013 Feb;37(2):254-62. doi: 10.1038/ijo.2012.42. Epub 2012 Mar 27.

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