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Items: 28

1.

Membrane topologies of PEX13 and PEX14 provide new insights on the mechanism of protein import into peroxisomes.

Barros-Barbosa A, Ferreira MJ, Rodrigues TA, Pedrosa AG, Grou CP, Pinto MP, Fransen M, Francisco T, Azevedo JE.

FEBS J. 2019 Jan;286(1):205-222. doi: 10.1111/febs.14697. Epub 2018 Nov 28.

2.

Sp1 phosphorylation by ATM downregulates BER and promotes cell elimination in response to persistent DNA damage.

Fletcher SC, Grou CP, Legrand AJ, Chen X, Soderstrom K, Poletto M, Dianov GL.

Nucleic Acids Res. 2018 Feb 28;46(4):1834-1846. doi: 10.1093/nar/gkx1291.

3.

Determining the Topology of Peroxisomal Proteins Using Protease Protection Assays.

Francisco T, Dias AF, Pedrosa AG, Grou CP, Rodrigues TA, Azevedo JE.

Methods Mol Biol. 2017;1595:27-35. doi: 10.1007/978-1-4939-6937-1_3.

PMID:
28409448
4.

A cell-free organelle-based in vitro system for studying the peroxisomal protein import machinery.

Rodrigues TA, Francisco T, Dias AF, Pedrosa AG, Grou CP, Azevedo JE.

Nat Protoc. 2016 Dec;11(12):2454-2469. doi: 10.1038/nprot.2016.147. Epub 2016 Nov 10.

PMID:
27831570
5.

Evaluation of the activity and substrate specificity of the human SENP family of SUMO proteases.

Mendes AV, Grou CP, Azevedo JE, Pinto MP.

Biochim Biophys Acta. 2016 Jan;1863(1):139-47. doi: 10.1016/j.bbamcr.2015.10.020. Epub 2015 Oct 30.

6.

The first minutes in the life of a peroxisomal matrix protein.

Dias AF, Francisco T, Rodrigues TA, Grou CP, Azevedo JE.

Biochim Biophys Acta. 2016 May;1863(5):814-20. doi: 10.1016/j.bbamcr.2015.09.025. Epub 2015 Sep 25. Review.

7.

The de novo synthesis of ubiquitin: identification of deubiquitinases acting on ubiquitin precursors.

Grou CP, Pinto MP, Mendes AV, Domingues P, Azevedo JE.

Sci Rep. 2015 Aug 3;5:12836. doi: 10.1038/srep12836.

8.

Revisiting the intraperoxisomal pathway of mammalian PEX7.

Rodrigues TA, Grou CP, Azevedo JE.

Sci Rep. 2015 Jul 3;5:11806. doi: 10.1038/srep11806.

9.

The peroxisomal protein import machinery displays a preference for monomeric substrates.

Freitas MO, Francisco T, Rodrigues TA, Lismont C, Domingues P, Pinto MP, Grou CP, Fransen M, Azevedo JE.

Open Biol. 2015 Apr;5(4):140236. doi: 10.1098/rsob.140236.

10.

A PEX7-centered perspective on the peroxisomal targeting signal type 2-mediated protein import pathway.

Rodrigues TA, Alencastre IS, Francisco T, Brites P, Fransen M, Grou CP, Azevedo JE.

Mol Cell Biol. 2014 Aug;34(15):2917-28. doi: 10.1128/MCB.01727-13. Epub 2014 May 27.

11.

PEX5, the shuttling import receptor for peroxisomal matrix proteins, is a redox-sensitive protein.

Apanasets O, Grou CP, Van Veldhoven PP, Brees C, Wang B, Nordgren M, Dodt G, Azevedo JE, Fransen M.

Traffic. 2014 Jan;15(1):94-103. doi: 10.1111/tra.12129. Epub 2013 Oct 31.

12.

A cargo-centered perspective on the PEX5 receptor-mediated peroxisomal protein import pathway.

Francisco T, Rodrigues TA, Freitas MO, Grou CP, Carvalho AF, Sá-Miranda C, Pinto MP, Azevedo JE.

J Biol Chem. 2013 Oct 4;288(40):29151-9. doi: 10.1074/jbc.M113.487140. Epub 2013 Aug 20.

13.

Ubiquitin in the peroxisomal protein import pathway.

Francisco T, Rodrigues TA, Pinto MP, Carvalho AF, Azevedo JE, Grou CP.

Biochimie. 2014 Mar;98:29-35. doi: 10.1016/j.biochi.2013.08.003. Epub 2013 Aug 14. Review.

PMID:
23954799
14.

Heat shock induces a massive but differential inactivation of SUMO-specific proteases.

Pinto MP, Carvalho AF, Grou CP, Rodríguez-Borges JE, Sá-Miranda C, Azevedo JE.

Biochim Biophys Acta. 2012 Oct;1823(10):1958-66. doi: 10.1016/j.bbamcr.2012.07.010. Epub 2012 Jul 31.

15.

Identification of ubiquitin-specific protease 9X (USP9X) as a deubiquitinase acting on ubiquitin-peroxin 5 (PEX5) thioester conjugate.

Grou CP, Francisco T, Rodrigues TA, Freitas MO, Pinto MP, Carvalho AF, Domingues P, Wood SA, Rodríguez-Borges JE, Sá-Miranda C, Fransen M, Azevedo JE.

J Biol Chem. 2012 Apr 13;287(16):12815-27. doi: 10.1074/jbc.M112.340158. Epub 2012 Feb 27.

16.

High-yield expression in Escherichia coli and purification of mouse ubiquitin-activating enzyme E1.

Carvalho AF, Pinto MP, Grou CP, Vitorino R, Domingues P, Yamao F, Sá-Miranda C, Azevedo JE.

Mol Biotechnol. 2012 Jul;51(3):254-61. doi: 10.1007/s12033-011-9463-x.

PMID:
22012022
17.

PEX5 protein binds monomeric catalase blocking its tetramerization and releases it upon binding the N-terminal domain of PEX14.

Freitas MO, Francisco T, Rodrigues TA, Alencastre IS, Pinto MP, Grou CP, Carvalho AF, Fransen M, Sá-Miranda C, Azevedo JE.

J Biol Chem. 2011 Nov 25;286(47):40509-19. doi: 10.1074/jbc.M111.287201. Epub 2011 Oct 5.

18.

The cytosolic domain of PEX3, a protein involved in the biogenesis of peroxisomes, binds membrane lipids.

Pinto MP, Grou CP, Fransen M, Sá-Miranda C, Azevedo JE.

Biochim Biophys Acta. 2009 Nov;1793(11):1669-75. doi: 10.1016/j.bbamcr.2009.08.007. Epub 2009 Aug 26.

19.

Mapping the cargo protein membrane translocation step into the PEX5 cycling pathway.

Alencastre IS, Rodrigues TA, Grou CP, Fransen M, Sá-Miranda C, Azevedo JE.

J Biol Chem. 2009 Oct 2;284(40):27243-51. doi: 10.1074/jbc.M109.032565. Epub 2009 Jul 23.

20.

Properties of the ubiquitin-pex5p thiol ester conjugate.

Grou CP, Carvalho AF, Pinto MP, Huybrechts SJ, Sá-Miranda C, Fransen M, Azevedo JE.

J Biol Chem. 2009 Apr 17;284(16):10504-13. doi: 10.1074/jbc.M808978200. Epub 2009 Feb 10.

21.

The peroxisomal protein import machinery--a case report of transient ubiquitination with a new flavor.

Grou CP, Carvalho AF, Pinto MP, Alencastre IS, Rodrigues TA, Freitas MO, Francisco T, Sá-Miranda C, Azevedo JE.

Cell Mol Life Sci. 2009 Jan;66(2):254-62. doi: 10.1007/s00018-008-8415-5. Review.

PMID:
18810320
22.

Members of the E2D (UbcH5) family mediate the ubiquitination of the conserved cysteine of Pex5p, the peroxisomal import receptor.

Grou CP, Carvalho AF, Pinto MP, Wiese S, Piechura H, Meyer HE, Warscheid B, Sá-Miranda C, Azevedo JE.

J Biol Chem. 2008 May 23;283(21):14190-7. doi: 10.1074/jbc.M800402200. Epub 2008 Mar 22.

23.

Proteomics characterization of mouse kidney peroxisomes by tandem mass spectrometry and protein correlation profiling.

Wiese S, Gronemeyer T, Ofman R, Kunze M, Grou CP, Almeida JA, Eisenacher M, Stephan C, Hayen H, Schollenberger L, Korosec T, Waterham HR, Schliebs W, Erdmann R, Berger J, Meyer HE, Just W, Azevedo JE, Wanders RJ, Warscheid B.

Mol Cell Proteomics. 2007 Dec;6(12):2045-57. Epub 2007 Sep 2.

24.

Ubiquitination of mammalian Pex5p, the peroxisomal import receptor.

Carvalho AF, Pinto MP, Grou CP, Alencastre IS, Fransen M, Sá-Miranda C, Azevedo JE.

J Biol Chem. 2007 Oct 26;282(43):31267-72. Epub 2007 Aug 28.

25.

Functional characterization of two missense mutations in Pex5p - C11S and N526K.

Carvalho AF, Grou CP, Pinto MP, Alencastre IS, Costa-Rodrigues J, Fransen M, Sá-Miranda C, Azevedo JE.

Biochim Biophys Acta. 2007 Jul;1773(7):1141-8. Epub 2007 Apr 29.

26.

The import competence of a peroxisomal membrane protein is determined by Pex19p before the docking step.

Pinto MP, Grou CP, Alencastre IS, Oliveira ME, Sá-Miranda C, Fransen M, Azevedo JE.

J Biol Chem. 2006 Nov 10;281(45):34492-502. Epub 2006 Sep 15.

27.

Ontogeny of the common carp (Cyprinus carpio L.) innate immune system.

Huttenhuis HB, Taverne-Thiele AJ, Grou CP, Bergsma J, Saeij JP, Nakayasu C, Rombout JH.

Dev Comp Immunol. 2006;30(6):557-74. Epub 2005 Sep 6.

PMID:
16406121
28.

Carp (Cyprinus carpio L.) innate immune factors are present before hatching.

Huttenhuis HB, Grou CP, Taverne-Thiele AJ, Taverne N, Rombout JH.

Fish Shellfish Immunol. 2006 Apr;20(4):586-96. Epub 2005 Oct 5.

PMID:
16169251

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