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Items: 1 to 50 of 62

1.

Connectomics and molecular imaging in neurodegeneration.

Bischof GN, Ewers M, Franzmeier N, Grothe MJ, Hoenig M, Kocagoncu E, Neitzel J, Rowe JB, Strafella A, Drzezga A, van Eimeren T; MINC faculty.

Eur J Nucl Med Mol Imaging. 2019 Jul 11. doi: 10.1007/s00259-019-04394-5. [Epub ahead of print]

PMID:
31292699
2.

Characterizing the Molecular Architecture of Cortical Regions Associated with High Educational Attainment in Older Individuals.

Bartrés-Faz D, González-Escamilla G, Vaqué-Alcázar L, Abellaneda-Pérez K, Valls-Pedret C, Ros E, Grothe MJ.

J Neurosci. 2019 Jun 5;39(23):4566-4575. doi: 10.1523/JNEUROSCI.2370-18.2019. Epub 2019 Apr 8.

PMID:
30962275
3.

The BDNFVal66Met SNP modulates the association between beta-amyloid and hippocampal disconnection in Alzheimer's disease.

Franzmeier N, Ren J, Damm A, Monté-Rubio G, Boada M, Ruiz A, Ramirez A, Jessen F, Düzel E, Rodríguez Gómez O, Benzinger T, Goate A, Karch CM, Fagan AM, McDade E, Buerger K, Levin J, Duering M, Dichgans M, Suárez-Calvet M, Haass C, Gordon BA, Lim YY, Masters CL, Janowitz D, Catak C, Wolfsgruber S, Wagner M, Milz E, Moreno-Grau S, Teipel S, Grothe MJ, Kilimann I, Rossor M, Fox N, Laske C, Chhatwal J, Falkai P, Perneczky R, Lee JH, Spottke A, Boecker H, Brosseron F, Fliessbach K, Heneka MT, Nestor P, Peters O, Fuentes M, Menne F, Priller J, Spruth EJ, Franke C, Schneider A, Westerteicher C, Speck O, Wiltfang J, Bartels C, Araque Caballero MÁ, Metzger C, Bittner D, Salloway S, Danek A, Hassenstab J, Yakushev I, Schofield PR, Morris JC, Bateman RJ, Ewers M.

Mol Psychiatry. 2019 Mar 21. doi: 10.1038/s41380-019-0404-6. [Epub ahead of print]

4.

Applicability of in vivo staging of regional amyloid burden in a cognitively normal cohort with subjective memory complaints: the INSIGHT-preAD study.

Sakr FA, Grothe MJ, Cavedo E, Jelistratova I, Habert MO, Dyrba M, Gonzalez-Escamilla G, Bertin H, Locatelli M, Lehericy S, Teipel S, Dubois B, Hampel H; INSIGHT-preAD study group; Alzheimer Precision Medicine Initiative (APMI).

Alzheimers Res Ther. 2019 Jan 31;11(1):15. doi: 10.1186/s13195-019-0466-3.

5.

Effective connectivity in the default mode network is distinctively disrupted in Alzheimer's disease-A simultaneous resting-state FDG-PET/fMRI study.

Scherr M, Utz L, Tahmasian M, Pasquini L, Grothe MJ, Rauschecker JP, Grimmer T, Drzezga A, Sorg C, Riedl V.

Hum Brain Mapp. 2019 Jan 30. doi: 10.1002/hbm.24517. [Epub ahead of print]

PMID:
30697878
6.

Subregional volume reduction of the cholinergic forebrain in subjective cognitive decline (SCD).

Scheef L, Grothe MJ, Koppara A, Daamen M, Boecker H, Biersack H, Schild HH, Wagner M, Teipel S, Jessen F.

Neuroimage Clin. 2019;21:101612. doi: 10.1016/j.nicl.2018.101612. Epub 2018 Nov 27.

7.

Neurogenetic contributions to amyloid beta and tau spreading in the human cortex.

Sepulcre J, Grothe MJ, d'Oleire Uquillas F, Ortiz-Terán L, Diez I, Yang HS, Jacobs HIL, Hanseeuw BJ, Li Q, El-Fakhri G, Sperling RA, Johnson KA.

Nat Med. 2018 Dec;24(12):1910-1918. doi: 10.1038/s41591-018-0206-4. Epub 2018 Oct 29.

8.

Relationship between Basal Forebrain Resting-State Functional Connectivity and Brain Amyloid-β Deposition in Cognitively Intact Older Adults with Subjective Memory Complaints.

Chiesa PA, Cavedo E, Grothe MJ, Houot M, Teipel SJ, Potier MC, Habert MO, Lista S, Dubois B, Hampel H; INSIGHT-preAD Study Group and the Alzheimer Precision Medicine Initiative (APMI).

Radiology. 2019 Jan;290(1):167-176. doi: 10.1148/radiol.2018180268. Epub 2018 Oct 23.

PMID:
30351255
9.

The corticotopic organization of the human basal forebrain as revealed by regionally selective functional connectivity profiles.

Fritz HJ, Ray N, Dyrba M, Sorg C, Teipel S, Grothe MJ.

Hum Brain Mapp. 2019 Feb 15;40(3):868-878. doi: 10.1002/hbm.24417. Epub 2018 Oct 11.

PMID:
30311315
10.

Sex differences in functional and molecular neuroimaging biomarkers of Alzheimer's disease in cognitively normal older adults with subjective memory complaints.

Cavedo E, Chiesa PA, Houot M, Ferretti MT, Grothe MJ, Teipel SJ, Lista S, Habert MO, Potier MC, Dubois B, Hampel H; INSIGHT-preAD Study Group; Alzheimer Precision Medicine Initiative (APMI).

Alzheimers Dement. 2018 Sep;14(9):1204-1215. doi: 10.1016/j.jalz.2018.05.014. Epub 2018 Jul 7. Review.

PMID:
30201102
11.

Basal Forebrain Volume, but Not Hippocampal Volume, Is a Predictor of Global Cognitive Decline in Patients With Alzheimer's Disease Treated With Cholinesterase Inhibitors.

Teipel SJ, Cavedo E, Hampel H, Grothe MJ; Alzheimer's Disease Neuroimaging Initiative; Alzheimer Precision Medicine Initiative (APMI).

Front Neurol. 2018 Aug 14;9:642. doi: 10.3389/fneur.2018.00642. eCollection 2018.

12.

Molecular properties underlying regional vulnerability to Alzheimer's disease pathology.

Grothe MJ, Sepulcre J, Gonzalez-Escamilla G, Jelistratova I, Schöll M, Hansson O, Teipel SJ; Alzheimer’s Disease Neuroimaging Initiative.

Brain. 2018 Sep 1;141(9):2755-2771. doi: 10.1093/brain/awy189.

13.

Effect of Alzheimer's disease risk and protective factors on cognitive trajectories in subjective memory complainers: An INSIGHT-preAD study.

Teipel SJ, Cavedo E, Lista S, Habert MO, Potier MC, Grothe MJ, Epelbaum S, Sambati L, Gagliardi G, Toschi N, Greicius MD, Dubois B, Hampel H; INSIGHT-preAD study group; Alzheimer Precision Medicine Initiative (APMI).

Alzheimers Dement. 2018 Sep;14(9):1126-1136. doi: 10.1016/j.jalz.2018.04.004. Epub 2018 May 21.

PMID:
29792873
14.

Magnetic resonance imaging-based hippocampus volume for prediction of dementia in mild cognitive impairment: Why does the measurement method matter so little?

Buchert R, Lange C, Suppa P, Apostolova I, Spies L, Teipel S, Dubois B, Hampel H, Grothe MJ.

Alzheimers Dement. 2018 Jul;14(7):976-978. doi: 10.1016/j.jalz.2018.03.006. Epub 2018 Apr 19. No abstract available.

PMID:
29679575
15.

Recent advances in cholinergic imaging and cognitive decline-Revisiting the cholinergic hypothesis of dementia.

Bohnen NI, Grothe MJ, Ray NJ, Müller MLTM, Teipel SJ.

Curr Geriatr Rep. 2018 Mar;7(1):1-11. doi: 10.1007/s13670-018-0234-4. Epub 2018 Jan 13.

16.

Impact of plasma glucose level on the pattern of brain FDG uptake and the predictive power of FDG PET in mild cognitive impairment.

Apostolova I, Lange C, Suppa P, Spies L, Klutmann S, Adam G, Grothe MJ, Buchert R; Alzheimer’s Disease Neuroimaging Initiative.

Eur J Nucl Med Mol Imaging. 2018 Jul;45(8):1417-1422. doi: 10.1007/s00259-018-3985-4. Epub 2018 Mar 3.

PMID:
29502311
17.

Hypermetabolism in the hippocampal formation of cognitively impaired patients indicates detrimental maladaptation.

Apostolova I, Lange C, Mäurer A, Suppa P, Spies L, Grothe MJ, Nierhaus T, Fiebach JB, Steinhagen-Thiessen E, Buchert R; Alzheimer's Disease Neuroimaging Initiative.

Neurobiol Aging. 2018 May;65:41-50. doi: 10.1016/j.neurobiolaging.2018.01.002. Epub 2018 Jan 31.

PMID:
29407465
18.

In vivo cholinergic basal forebrain atrophy predicts cognitive decline in de novo Parkinson's disease.

Ray NJ, Bradburn S, Murgatroyd C, Toseeb U, Mir P, Kountouriotis GK, Teipel SJ, Grothe MJ.

Brain. 2018 Jan 1;141(1):165-176. doi: 10.1093/brain/awx310.

19.

Mean diffusivity in cortical gray matter in Alzheimer's disease: The importance of partial volume correction.

Henf J, Grothe MJ, Brueggen K, Teipel S, Dyrba M.

Neuroimage Clin. 2017 Oct 4;17:579-586. doi: 10.1016/j.nicl.2017.10.005. eCollection 2018.

20.

No association of cortical amyloid load and EEG connectivity in older people with subjective memory complaints.

Teipel S, Bakardjian H, Gonzalez-Escamilla G, Cavedo E, Weschke S, Dyrba M, Grothe MJ, Potier MC, Habert MO, Dubois B, Hampel H; INSIGHT-preAD study group.

Neuroimage Clin. 2017 Oct 29;17:435-443. doi: 10.1016/j.nicl.2017.10.031. eCollection 2018.

21.

In vivo staging of regional amyloid deposition.

Grothe MJ, Barthel H, Sepulcre J, Dyrba M, Sabri O, Teipel SJ; Alzheimer's Disease Neuroimaging Initiative.

Neurology. 2017 Nov 14;89(20):2031-2038. doi: 10.1212/WNL.0000000000004643. Epub 2017 Oct 18.

22.

Reduced basal forebrain atrophy progression in a randomized Donepezil trial in prodromal Alzheimer's disease.

Cavedo E, Grothe MJ, Colliot O, Lista S, Chupin M, Dormont D, Houot M, Lehéricy S, Teipel S, Dubois B, Hampel H; Hippocampus Study Group.

Sci Rep. 2017 Sep 15;7(1):11706. doi: 10.1038/s41598-017-09780-3.

23.

Comparison of Different Hypotheses Regarding the Spread of Alzheimer's Disease Using Markov Random Fields and Multimodal Imaging.

Dyrba M, Grothe MJ, Mohammadi A, Binder H, Kirste T, Teipel SJ; Alzheimer’s Disease Neuroimaging Initiative.

J Alzheimers Dis. 2018;65(3):731-746. doi: 10.3233/JAD-161197.

PMID:
28697557
24.

Cortical amyloid accumulation is associated with alterations of structural integrity in older people with subjective memory complaints.

Teipel SJ, Cavedo E, Weschke S, Grothe MJ, Rojkova K, Fontaine G, Dauphinot L, Gonzalez-Escamilla G, Potier MC, Bertin H, Habert MO, Dubois B, Hampel H; INSIGHT-preAD study group.

Neurobiol Aging. 2017 Sep;57:143-152. doi: 10.1016/j.neurobiolaging.2017.05.016. Epub 2017 May 31.

PMID:
28646687
25.

Hierarchical Organization of Tau and Amyloid Deposits in the Cerebral Cortex.

Sepulcre J, Grothe MJ, Sabuncu M, Chhatwal J, Schultz AP, Hanseeuw B, El Fakhri G, Sperling R, Johnson KA.

JAMA Neurol. 2017 Jul 1;74(7):813-820. doi: 10.1001/jamaneurol.2017.0263.

26.

Individual Correspondence of Amyloid-β and Intrinsic Connectivity in the Posterior Default Mode Network Across Stages of Alzheimer's Disease.

Pasquini L, Benson G, Grothe MJ, Utz L, Myers NE, Yakushev I, Grimmer T, Scherr M, Sorg C; Alzheimer’s Disease Neuroimaging Initiative.

J Alzheimers Dis. 2017;58(3):763-773. doi: 10.3233/JAD-170096.

PMID:
28482640
27.

Basal forebrain mediated increase in brain CRF is associated with increased cholinergic tone and depression.

Gollan JK, Dong H, Bruno D, Nierenberg J, Nobrega JN, Grothe MJ, Pollock BG, Marmar CR, Teipel S, Csernansky JG, Pomara N.

Psychiatry Res Neuroimaging. 2017 Jun 30;264:76-81. doi: 10.1016/j.pscychresns.2017.04.009. Epub 2017 Apr 23. No abstract available.

PMID:
28477491
28.

Tau Pathology Distribution in Alzheimer's disease Corresponds Differentially to Cognition-Relevant Functional Brain Networks.

Hansson O, Grothe MJ, Strandberg TO, Ohlsson T, Hägerström D, Jögi J, Smith R, Schöll M.

Front Neurosci. 2017 Mar 31;11:167. doi: 10.3389/fnins.2017.00167. eCollection 2017.

29.

Does Functional Connectivity Provide a Marker for Cognitive Rehabilitation Effects in Alzheimer's Disease? An Interventional Study.

Ochmann S, Dyrba M, Grothe MJ, Kasper E, Webel S, Hauenstein K, Teipel SJ.

J Alzheimers Dis. 2017;57(4):1303-1313. doi: 10.3233/JAD-160773.

30.

Reference standard space hippocampus labels according to the European Alzheimer's Disease Consortium-Alzheimer's Disease Neuroimaging Initiative harmonized protocol: Utility in automated volumetry.

Wolf D, Bocchetta M, Preboske GM, Boccardi M, Grothe MJ; Alzheimer's Disease Neuroimaging Initiative.

Alzheimers Dement. 2017 Aug;13(8):893-902. doi: 10.1016/j.jalz.2017.01.009. Epub 2017 Feb 24.

PMID:
28238738
31.

Multicenter stability of resting state fMRI in the detection of Alzheimer's disease and amnestic MCI.

Teipel SJ, Wohlert A, Metzger C, Grimmer T, Sorg C, Ewers M, Meisenzahl E, Klöppel S, Borchardt V, Grothe MJ, Walter M, Dyrba M.

Neuroimage Clin. 2017 Jan 18;14:183-194. doi: 10.1016/j.nicl.2017.01.018. eCollection 2017.

32.

Reduced Cholinergic Basal Forebrain Integrity Links Neonatal Complications and Adult Cognitive Deficits After Premature Birth.

Grothe MJ, Scheef L, Bäuml J, Meng C, Daamen M, Baumann N, Zimmer C, Teipel S, Bartmann P, Boecker H, Wolke D, Wohlschläger A, Sorg C.

Biol Psychiatry. 2017 Jul 15;82(2):119-126. doi: 10.1016/j.biopsych.2016.12.008. Epub 2016 Dec 15.

PMID:
28129944
33.

Robust Detection of Impaired Resting State Functional Connectivity Networks in Alzheimer's Disease Using Elastic Net Regularized Regression.

Teipel SJ, Grothe MJ, Metzger CD, Grimmer T, Sorg C, Ewers M, Franzmeier N, Meisenzahl E, Klöppel S, Borchardt V, Walter M, Dyrba M.

Front Aging Neurosci. 2017 Jan 4;8:318. doi: 10.3389/fnagi.2016.00318. eCollection 2016.

34.

Multimodal characterization of older APOE2 carriers reveals selective reduction of amyloid load.

Grothe MJ, Villeneuve S, Dyrba M, Bartrés-Faz D, Wirth M; Alzheimer's Disease Neuroimaging Initiative.

Neurology. 2017 Feb 7;88(6):569-576. doi: 10.1212/WNL.0000000000003585. Epub 2017 Jan 6.

35.

PETPVE12: an SPM toolbox for Partial Volume Effects correction in brain PET - Application to amyloid imaging with AV45-PET.

Gonzalez-Escamilla G, Lange C, Teipel S, Buchert R, Grothe MJ; Alzheimer's Disease Neuroimaging Initiative.

Neuroimage. 2017 Feb 15;147:669-677. doi: 10.1016/j.neuroimage.2016.12.077. Epub 2016 Dec 28.

PMID:
28039094
36.

Neuronal correlates of serial position performance in amnestic mild cognitive impairment.

Kasper E, Brueggen K, Grothe MJ, Bruno D, Pomara N, Unterauer E, Duering M, Ewers M, Teipel S, Buerger K.

Neuropsychology. 2016 Nov;30(8):906-914. Epub 2016 May 16.

PMID:
27182709
37.

Atrophy and structural covariance of the cholinergic basal forebrain in primary progressive aphasia.

Teipel S, Raiser T, Riedl L, Riederer I, Schroeter ML, Bisenius S, Schneider A, Kornhuber J, Fliessbach K, Spottke A, Grothe MJ, Prudlo J, Kassubek J, Ludolph A, Landwehrmeyer B, Straub S, Otto M, Danek A; FTLDc study group.

Cortex. 2016 Oct;83:124-35. doi: 10.1016/j.cortex.2016.07.004. Epub 2016 Jul 16.

38.

Contribution of the Cholinergic System to Verbal Memory Performance in Mild Cognitive Impairment.

Peter J, Lahr J, Minkova L, Lauer E, Grothe MJ, Teipel S, Köstering L, Kaller CP, Heimbach B, Hüll M, Normann C, Nissen C, Reis J, Klöppel S.

J Alzheimers Dis. 2016 Jun 18;53(3):991-1001. doi: 10.3233/JAD-160273.

39.

Hippocampal volume and integrity as predictors of cognitive decline in intact elderly.

Bruno D, Ciarleglio A, Grothe MJ, Nierenberg J, Bachman AH, Teipel SJ, Petkova E, Ardekani BA, Pomara N.

Neuroreport. 2016 Aug 3;27(11):869-73. doi: 10.1097/WNR.0000000000000629.

40.

Hippocampus and basal forebrain volumes modulate effects of anticholinergic treatment on delayed recall in healthy older adults.

Teipel SJ, Bruno D, Grothe MJ, Nierenberg J, Pomara N.

Alzheimers Dement (Amst). 2015 May 7;1(2):216-9. doi: 10.1016/j.dadm.2015.01.007. eCollection 2015 Jun.

41.

Association Between Smoking and Cholinergic Basal Forebrain Volume in Healthy Aging and Prodromal and Dementia Stages of Alzheimer's Disease.

Teipel S, Grothe MJ; Alzheimer’s Disease Neuroimaging Initiative.

J Alzheimers Dis. 2016 Apr 12;52(4):1443-51. doi: 10.3233/JAD-151100.

PMID:
27079707
42.

The European DTI Study on Dementia - A multicenter DTI and MRI study on Alzheimer's disease and Mild Cognitive Impairment.

Brueggen K, Grothe MJ, Dyrba M, Fellgiebel A, Fischer F, Filippi M, Agosta F, Nestor P, Meisenzahl E, Blautzik J, Frölich L, Hausner L, Bokde ALW, Frisoni G, Pievani M, Klöppel S, Prvulovic D, Barkhof F, Pouwels PJW, Schröder J, Hampel H, Hauenstein K, Teipel S.

Neuroimage. 2017 Jan;144(Pt B):305-308. doi: 10.1016/j.neuroimage.2016.03.067. Epub 2016 Apr 2.

PMID:
27046114
43.

Measuring Cortical Connectivity in Alzheimer's Disease as a Brain Neural Network Pathology: Toward Clinical Applications.

Teipel S, Grothe MJ, Zhou J, Sepulcre J, Dyrba M, Sorg C, Babiloni C.

J Int Neuropsychol Soc. 2016 Feb;22(2):138-63. doi: 10.1017/S1355617715000995. Review.

PMID:
26888613
44.

Predictors of cognitive decline and treatment response in a clinical trial on suspected prodromal Alzheimer's disease.

Teipel SJ, Cavedo E, Grothe MJ, Lista S, Galluzzi S, Colliot O, Chupin M, Bakardjian H, Dormont D, Dubois B, Hampel H; Hippocampus Study Group.

Neuropharmacology. 2016 Sep;108:128-35. doi: 10.1016/j.neuropharm.2016.02.005. Epub 2016 Feb 10.

PMID:
26876309
45.

The complex link between amyloid and neuronal dysfunction in Alzheimer's disease.

Sorg C, Grothe MJ.

Brain. 2015 Dec;138(Pt 12):3472-5. doi: 10.1093/brain/awv302. No abstract available.

PMID:
26598492
46.

Output order and variability in free recall are linked to cognitive ability and hippocampal volume in elderly individuals.

Bruno D, Grothe MJ, Nierenberg J, Sidtis JJ, Teipel SJ, Pomara N.

Neuropsychologia. 2016 Jan 8;80:126-132. doi: 10.1016/j.neuropsychologia.2015.11.014. Epub 2015 Nov 22.

47.

Does posterior cingulate hypometabolism result from disconnection or local pathology across preclinical and clinical stages of Alzheimer's disease?

Teipel S, Grothe MJ; Alzheimer´s Disease Neuroimaging Initiative.

Eur J Nucl Med Mol Imaging. 2016 Mar;43(3):526-36. doi: 10.1007/s00259-015-3222-3. Epub 2015 Nov 10.

48.

Spatial patterns of atrophy, hypometabolism, and amyloid deposition in Alzheimer's disease correspond to dissociable functional brain networks.

Grothe MJ, Teipel SJ; Alzheimer's Disease Neuroimaging Initiative.

Hum Brain Mapp. 2016 Jan;37(1):35-53. doi: 10.1002/hbm.23018. Epub 2015 Oct 6.

49.

Basal Forebrain and Hippocampus as Predictors of Conversion to Alzheimer's Disease in Patients with Mild Cognitive Impairment - A Multicenter DTI and Volumetry Study.

Brueggen K, Dyrba M, Barkhof F, Hausner L, Filippi M, Nestor PJ, Hauenstein K, Klöppel S, Grothe MJ, Kasper E, Teipel SJ.

J Alzheimers Dis. 2015;48(1):197-204. doi: 10.3233/JAD-150063.

PMID:
26401940
50.

Multimodal imaging in Alzheimer's disease: validity and usefulness for early detection.

Teipel S, Drzezga A, Grothe MJ, Barthel H, Chételat G, Schuff N, Skudlarski P, Cavedo E, Frisoni GB, Hoffmann W, Thyrian JR, Fox C, Minoshima S, Sabri O, Fellgiebel A.

Lancet Neurol. 2015 Oct;14(10):1037-53. doi: 10.1016/S1474-4422(15)00093-9. Epub 2015 Aug 26. Review.

PMID:
26318837

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