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A chromatin-based signalling mechanism directs the switch from mutagenic to error-free repair of DNA double strand breaks.

Bartke T, Groth A.

Mol Cell Oncol. 2019 May 7;6(4):1605820. doi: 10.1080/23723556.2019.1605820. eCollection 2019.


[Ear aid in Myanmar].

Biesinger E, Dillinger J, Groth A, Heiden C, Olze H, Prechtl J, Schuss JU, Rasp G, Rieffert M, Wagner G, Weitzsäcker W.

HNO. 2019 Jun 4. doi: 10.1007/s00106-019-0689-4. [Epub ahead of print] Review. German.


Transcription Restart Establishes Chromatin Accessibility after DNA Replication.

Stewart-Morgan KR, Reverón-Gómez N, Groth A.

Mol Cell. 2019 May 16. pii: S1097-2765(19)30352-1. doi: 10.1016/j.molcel.2019.04.033. [Epub ahead of print]


H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.

Nakamura K, Saredi G, Becker JR, Foster BM, Nguyen NV, Beyer TE, Cesa LC, Faull PA, Lukauskas S, Frimurer T, Chapman JR, Bartke T, Groth A.

Nat Cell Biol. 2019 Mar;21(3):311-318. doi: 10.1038/s41556-019-0282-9. Epub 2019 Feb 25.


Comparative Outcomes for the Treatment of Articular Cartilage Lesions in the Ankle With a DeNovo NT Natural Tissue Graft: Open Versus Arthroscopic Treatment.

Ryan PM, Turner RC, Anderson CD, Groth AT.

Orthop J Sports Med. 2018 Dec 14;6(12):2325967118812710. doi: 10.1177/2325967118812710. eCollection 2018 Dec.


Primary data, claims data, and linked data in observational research: the case of COPD in Germany.

Mueller S, Gottschalk F, Groth A, Meeraus W, Driessen M, Kohlmann T, Wilke T.

Respir Res. 2018 Aug 30;19(1):161. doi: 10.1186/s12931-018-0865-1.


Accurate Recycling of Parental Histones Reproduces the Histone Modification Landscape during DNA Replication.

Reverón-Gómez N, González-Aguilera C, Stewart-Morgan KR, Petryk N, Flury V, Graziano S, Johansen JV, Jakobsen JS, Alabert C, Groth A.

Mol Cell. 2018 Oct 18;72(2):239-249.e5. doi: 10.1016/j.molcel.2018.08.010. Epub 2018 Aug 23.


MCM2 promotes symmetric inheritance of modified histones during DNA replication.

Petryk N, Dalby M, Wenger A, Stromme CB, Strandsby A, Andersson R, Groth A.

Science. 2018 Sep 28;361(6409):1389-1392. doi: 10.1126/science.aau0294. Epub 2018 Aug 16.


Tousled-like kinases stabilize replication forks and show synthetic lethality with checkpoint and PARP inhibitors.

Lee SB, Segura-Bayona S, Villamor-Payà M, Saredi G, Todd MAM, Attolini CS, Chang TY, Stracker TH, Groth A.

Sci Adv. 2018 Aug 8;4(8):eaat4985. doi: 10.1126/sciadv.aat4985. eCollection 2018 Aug.


Ventral stabilization of thoracic kyphosis through bilateral intercostal thoracotomies using SOP (String of Pearls) plates contoured after a 3-dimensional print of the spine.

Mathiesen CB, de la Puerta B, Groth AM, Rutherford S, Cappello R.

Vet Surg. 2018 Aug;47(6):843-851. doi: 10.1111/vsu.12939. Epub 2018 Aug 9.


Acute hemodynamic changes by breathing hypoxic and hyperoxic gas mixtures in pulmonary arterial and chronic thromboembolic pulmonary hypertension.

Groth A, Saxer S, Bader PR, Lichtblau M, Furian M, Schneider SR, Schwarz EI, Bloch KE, Ulrich S.

Int J Cardiol. 2018 Nov 1;270:262-267. doi: 10.1016/j.ijcard.2018.05.127. Epub 2018 May 31.


Evaluation of complications and flap losses in mandibular reconstruction with microvascularized fibula flap.

Parise GK, Guebur MI, Ramos GHA, Groth AK, da Silva ABD, Sassi LM.

Oral Maxillofac Surg. 2018 Sep;22(3):281-284. doi: 10.1007/s10006-018-0701-2. Epub 2018 May 25.


Real-world effectiveness and safety of oral anticoagulation strategies in atrial fibrillation: a cohort study based on a German claims dataset.

Mueller S, Groth A, Spitzer SG, Schramm A, Pfaff A, Maywald U.

Pragmat Obs Res. 2018 May 1;9:1-10. doi: 10.2147/POR.S156521. eCollection 2018.


Preclinical pharmacokinetics and biodistribution of subcutaneously administered glycoPEGylated recombinant factor VIII (N8-GP) and development of a human pharmacokinetic prediction model.

Rode F, Almholt K, Petersen M, Kreilgaard M, Kjalke M, Karpf DM, Groth AV, Johansen PB, Larsen LF, Loftager M, Haaning J.

J Thromb Haemost. 2018 Jun;16(6):1141-1152. doi: 10.1111/jth.14013. Epub 2018 May 10.


Prediction of human pharmacokinetics of activated recombinant factor VII and B-domain truncated factor VIII from animal population pharmacokinetic models of haemophilia.

Larsen MS, Juul RV, Groth AV, Simonsson USH, Kristensen AT, Knudsen T, Agersø H, Kreilgaard M.

Eur J Pharm Sci. 2018 Mar 30;115:196-203. doi: 10.1016/j.ejps.2018.01.035. Epub 2018 Jan 31.


Chromatin Replication and Histone Dynamics.

Alabert C, Jasencakova Z, Groth A.

Adv Exp Med Biol. 2017;1042:311-333. doi: 10.1007/978-981-10-6955-0_15. Review.


Synchronization of world economic activity.

Groth A, Ghil M.

Chaos. 2017 Dec;27(12):127002. doi: 10.1063/1.5001820.


Persistence with VKA treatment in newly treated atrial fibrillation patients: an analysis based on a large sample of 38,076 German patients.

Wilke T, Groth A, Fuchs A, Pfannkuche M, Maywald U.

Eur J Clin Pharmacol. 2017 Nov;73(11):1437-1447. doi: 10.1007/s00228-017-2307-2. Epub 2017 Aug 5.


Effects of dissolution conditions on the properties of PVDF ultrafiltration membranes.

Ike IA, Zhang J, Groth A, Orbell JD, Duke M.

Ultrason Sonochem. 2017 Nov;39:716-726. doi: 10.1016/j.ultsonch.2017.05.041. Epub 2017 Jun 1.


Differential requirements for Tousled-like kinases 1 and 2 in mammalian development.

Segura-Bayona S, Knobel PA, González-Burón H, Youssef SA, Peña-Blanco A, Coyaud É, López-Rovira T, Rein K, Palenzuela L, Colombelli J, Forrow S, Raught B, Groth A, de Bruin A, Stracker TH.

Cell Death Differ. 2017 Nov;24(11):1872-1885. doi: 10.1038/cdd.2017.108. Epub 2017 Jul 14.


A new modeling approach allowing prediction and comparison of the long-term outcomes of treatments for hemophilia B.

Keep MV, Hoxer CS, Hemstock M, Groth AV, Knight C.

J Comp Eff Res. 2018 Jan;7(1):39-48. doi: 10.2217/cer-2017-0028. Epub 2017 May 30.


Histone chaperone networks shaping chromatin function.

Hammond CM, Strømme CB, Huang H, Patel DJ, Groth A.

Nat Rev Mol Cell Biol. 2017 Mar;18(3):141-158. doi: 10.1038/nrm.2016.159. Epub 2017 Jan 5. Review.


Implementing an Electronic Patient-Based Orthopaedic Outcomes System: Factors Affecting Patient Participation Compliance.

Tokish JM, Chisholm JN, Bottoni CR, Groth AT, Chen W, Orchowski JR.

Mil Med. 2017 Jan;182(1):e1626-e1630. doi: 10.7205/MILMED-D-15-00499.


Haem oxygenase-1 polymorphisms can affect HCV replication and treatment responses with different efficacy in humanized mice.

Kah J, Volz T, Lütgehetmann M, Groth A, Lohse AW, Tiegs G, Sass G, Dandri M.

Liver Int. 2017 Aug;37(8):1128-1137. doi: 10.1111/liv.13347. Epub 2017 Jan 25.


Forensic Analysis of Cigarette Ash-Brand Determination Through Trace-metal Analysis.

Groth AC, Barnes JH, Lewis C, Murray CK, Albahadily F, Jourdan TH.

J Forensic Sci. 2016 Jul;61(4):913-21. doi: 10.1111/1556-4029.13040. Epub 2016 Feb 9.


H4K20me0 marks post-replicative chromatin and recruits the TONSL–MMS22L DNA repair complex.

Saredi G, Huang H, Hammond CM, Alabert C, Bekker-Jensen S, Forne I, Reverón-Gómez N, Foster BM, Mlejnkova L, Bartke T, Cejka P, Mailand N, Imhof A, Patel DJ, Groth A.

Nature. 2016 Jun 30;534(7609):714-718. doi: 10.1038/nature18312. Epub 2016 Jun 22.


Modeled Perfluorooctanoic Acid (PFOA) Exposure and Liver Function in a Mid-Ohio Valley Community.

Darrow LA, Groth AC, Winquist A, Shin HM, Bartell SM, Steenland K.

Environ Health Perspect. 2016 Aug;124(8):1227-33. doi: 10.1289/ehp.1510391. Epub 2016 Mar 15.


Healthcare Burden and Costs Associated with Urinary Tract Infections in Type 2 Diabetes Mellitus Patients: An Analysis Based on a Large Sample of 456,586 German Patients.

Wilke T, Böttger B, Berg B, Groth A, Botteman M, Yu S, Fuchs A, Maywald U.

Nephron. 2016;132(3):215-26. doi: 10.1159/000444420. Epub 2016 Mar 2.


Pathogens trigger top-down climate forcing on ecosystem dynamics.

Edeline E, Groth A, Cazelles B, Claessen D, Winfield IJ, Ohlberger J, Asbjørn Vøllestad L, Stenseth NC, Ghil M.

Oecologia. 2016 Jun;181(2):519-32. doi: 10.1007/s00442-016-3575-8. Epub 2016 Feb 24.


Human liver chimeric mice as a new model of chronic hepatitis E virus infection and preclinical drug evaluation.

Allweiss L, Gass S, Giersch K, Groth A, Kah J, Volz T, Rapp G, Schöbel A, Lohse AW, Polywka S, Pischke S, Herker E, Dandri M, Lütgehetmann M.

J Hepatol. 2016 May;64(5):1033-1040. doi: 10.1016/j.jhep.2016.01.011. Epub 2016 Jan 22.


Paenibacillus larvae Phage Tripp Genome Has 378-Base-Pair Terminal Repeats.

Abraham J, Bousquet AC, Bruff E, Carson N, Clark A, Connell A, Davis Z, Dums J, Everington C, Groth A, Hawes N, McArthur N, McKenney C, Oufkir A, Pearce B, Rampal S, Rozier H, Schaff J, Slehria T, Carson S, Miller ES.

Genome Announc. 2016 Jan 7;4(1). pii: e01498-15. doi: 10.1128/genomeA.01498-15.


TRAIP is a PCNA-binding ubiquitin ligase that protects genome stability after replication stress.

Hoffmann S, Smedegaard S, Nakamura K, Mortuza GB, Räschle M, Ibañez de Opakua A, Oka Y, Feng Y, Blanco FJ, Mann M, Montoya G, Groth A, Bekker-Jensen S, Mailand N.

J Cell Biol. 2016 Jan 4;212(1):63-75. doi: 10.1083/jcb.201506071. Epub 2015 Dec 28.


Non-Persistence and Non-Adherence of Patients with Type 2 Diabetes Mellitus in Therapy with GLP-1 Receptor Agonists: A Retrospective Analysis.

Wilke T, Mueller S, Groth A, Berg B, Fuchs A, Sikirica M, Logie J, Martin A, Maywald U.

Diabetes Ther. 2016 Mar;7(1):105-24. doi: 10.1007/s13300-015-0149-4. Epub 2015 Dec 22.


BRPF3-HBO1 regulates replication origin activation and histone H3K14 acetylation.

Feng Y, Vlassis A, Roques C, Lalonde ME, González-Aguilera C, Lambert JP, Lee SB, Zhao X, Alabert C, Johansen JV, Paquet E, Yang XJ, Gingras AC, Côté J, Groth A.

EMBO J. 2016 Jan 18;35(2):176-92. doi: 10.15252/embj.201591293. Epub 2015 Nov 30.


Factors Associated with the Risk of Diabetes-Related Events: A Retrospective Analysis.

Mueller S, Wilke T, Groth A, Fuchs A, Seitz L, Kienhoefer J, Maywald U, Lundershausen R, Wehling M.

Value Health. 2015 Nov;18(7):A600-1. doi: 10.1016/j.jval.2015.09.2061. Epub 2015 Oct 20. No abstract available.


Bacterial isolates, antimicrobial susceptibility, and clinical characteristics of bacterial keratitis in dogs presenting to referral practice in Australia.

Hindley KE, Groth AD, King M, Graham K, Billson FM.

Vet Ophthalmol. 2016 Sep;19(5):418-26. doi: 10.1111/vop.12325. Epub 2015 Nov 1.


Epidemiology of urinary tract infections in type 2 diabetes mellitus patients: An analysis based on a large sample of 456,586 German T2DM patients.

Wilke T, Boettger B, Berg B, Groth A, Mueller S, Botteman M, Yu S, Fuchs A, Maywald U.

J Diabetes Complications. 2015 Nov-Dec;29(8):1015-23. doi: 10.1016/j.jdiacomp.2015.08.021. Epub 2015 Sep 1.


A unique binding mode enables MCM2 to chaperone histones H3-H4 at replication forks.

Huang H, Strømme CB, Saredi G, Hödl M, Strandsby A, González-Aguilera C, Chen S, Groth A, Patel DJ.

Nat Struct Mol Biol. 2015 Aug;22(8):618-26. doi: 10.1038/nsmb.3055. Epub 2015 Jul 13.


Genome Sequences of Six Paenibacillus larvae Siphoviridae Phages.

Carson S, Bruff E, DeFoor W, Dums J, Groth A, Hatfield T, Iyer A, Joshi K, McAdams S, Miles D, Miller D, Oufkir A, Raynor B, Riley S, Roland S, Rozier H, Talley S, Miller ES.

Genome Announc. 2015 Jun 18;3(3). pii: e00101-15. doi: 10.1128/genomeA.00101-15.


Remote sensing and conservation of isolated indigenous villages in Amazonia.

Walker RS, Hamilton MJ, Groth AA.

R Soc Open Sci. 2014 Nov 5;1(3):140246. doi: 10.1098/rsos.140246. eCollection 2014 Nov.


Subperiosteal abscesses in acute mastoiditis in 115 Swedish children.

Enoksson F, Groth A, Hultcrantz M, Stalfors J, Stenfeldt K, Hermansson A.

Int J Pediatr Otorhinolaryngol. 2015 Jul;79(7):1115-20. doi: 10.1016/j.ijporl.2015.05.002. Epub 2015 May 12.


[Somatosensoric tinnitus].

Biesinger E, Groth A, Höing R, Hölzl M.

HNO. 2015 Apr;63(4):266-71. doi: 10.1007/s00106-014-2971-9. German.


Cmr1/WDR76 defines a nuclear genotoxic stress body linking genome integrity and protein quality control.

Gallina I, Colding C, Henriksen P, Beli P, Nakamura K, Offman J, Mathiasen DP, Silva S, Hoffmann E, Groth A, Choudhary C, Lisby M.

Nat Commun. 2015 Mar 30;6:6533. doi: 10.1038/ncomms7533.


Two distinct modes for propagation of histone PTMs across the cell cycle.

Alabert C, Barth TK, Reverón-Gómez N, Sidoli S, Schmidt A, Jensen ON, Imhof A, Groth A.

Genes Dev. 2015 Mar 15;29(6):585-90. doi: 10.1101/gad.256354.114.


Treatment-dependent and treatment-independent risk factors associated with the risk of diabetes-related events: a retrospective analysis based on 229,042 patients with type 2 diabetes mellitus.

Wilke T, Mueller S, Groth A, Fuchs A, Seitz L, Kienhöfer J, Maywald U, Lundershausen R, Wehling M.

Cardiovasc Diabetol. 2015 Feb 3;14:14. doi: 10.1186/s12933-015-0179-2.


Effectiveness of sulphonylureas in the therapy of diabetes mellitus type 2 patients: an observational cohort study.

Wilke T, Mueller S, Groth A, Berg B, Hammar N, Tsai K, Fuchs A, Stephens S, Maywald U.

J Diabetes Metab Disord. 2016 Aug 2;15:28. doi: 10.1186/s40200-016-0251-9. eCollection 2015.


Determination of methane emission rates on a biogas plant using data from laser absorption spectrometry.

Groth A, Maurer C, Reiser M, Kranert M.

Bioresour Technol. 2015 Feb;178:359-361. doi: 10.1016/j.biortech.2014.09.112. Epub 2014 Oct 13.


Non-Adherence And Non-Persistence Related To Glp-1 Therapy In Patients With Diabetes Mellitus Type 2 (T2dm): Analysis of A Large German Claims-Based Dataset And Comparison To Oral Anti-Diabetics.

Wilke T, Groth A, Berg B, Sikirica M, Martin AA, Fuchs A, Maywald U.

Value Health. 2014 Nov;17(7):A359. doi: 10.1016/j.jval.2014.08.778. Epub 2014 Oct 26. No abstract available.


Real life anticoagulation treatment of patients with atrial fibrillation in Germany: extent and causes of anticoagulant under-use.

Wilke T, Groth A, Pfannkuche M, Harks O, Fuchs A, Maywald U, Krabbe B.

J Thromb Thrombolysis. 2015 Jul;40(1):97-107. doi: 10.1007/s11239-014-1136-8.


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