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Analysis of Damage and Wound Healing in the Retinal Pigmented Epithelium.

Donaldson KJ, Wu WF, Skelton H, Markand S, Ferdous S, Sellers J, Chrenek MA, Gefke I, Kim SM, Rha J, Liao KL, Grossniklaus HE, Jiang Y, Kong J, Boatright JH, Nickerson JM.

Adv Exp Med Biol. 2019;1185:425-430. doi: 10.1007/978-3-030-27378-1_70.


Consensus Nomenclature for Reporting Neovascular Age-Related Macular Degeneration Data: Consensus on Neovascular Age-Related Macular Degeneration Nomenclature Study Group.

Spaide RF, Jaffe GJ, Sarraf D, Freund KB, Sadda SR, Staurenghi G, Waheed NK, Chakravarthy U, Rosenfeld PJ, Holz FG, Souied EH, Cohen SY, Querques G, Ohno-Matsui K, Boyer D, Gaudric A, Blodi B, Baumal CR, Li X, Coscas GJ, Brucker A, Singerman L, Luthert P, Schmitz-Valckenberg S, Schmidt-Erfurth U, Grossniklaus HE, Wilson DJ, Guymer R, Yannuzzi LA, Chew EY, Csaky K, Monés JM, Pauleikhoff D, Tadayoni R, Fujimoto J.

Ophthalmology. 2019 Nov 14. pii: S0161-6420(19)32243-2. doi: 10.1016/j.ophtha.2019.11.004. [Epub ahead of print]


Primary ductal adenocarcinoma of the lacrimal gland: A review and report of five cases.

See TRO, Stålhammar G, Tang T, Manusow JS, Jordan DR, Nerad JA, Kersten RC, Yonkers M, Syed NA, Brownstein S, Grossniklaus HE.

Surv Ophthalmol. 2019 Dec 16. pii: S0039-6257(19)30289-9. doi: 10.1016/j.survophthal.2019.11.002. [Epub ahead of print] Review.


Basal Cell Carcinoma of the Eyelid With Metaplastic Bone Formation.

Schaffer LR, Kim HJ, Grossniklaus HE.

Ophthalmic Plast Reconstr Surg. 2019 Nov 27. doi: 10.1097/IOP.0000000000001554. [Epub ahead of print]


Characterization of LSD1 Expression Within the Murine Eye.

Ferdous S, Grossniklaus HE, Boatright JH, Nickerson JM.

Invest Ophthalmol Vis Sci. 2019 Nov 1;60(14):4619-4631. doi: 10.1167/iovs.19-26728.


Prediction of BAP1 Expression in Uveal Melanoma Using Densely-Connected Deep Classification Networks.

Sun M, Zhou W, Qi X, Zhang G, Girnita L, Seregard S, Grossniklaus HE, Yao Z, Zhou X, Stålhammar G.

Cancers (Basel). 2019 Oct 16;11(10). pii: E1579. doi: 10.3390/cancers11101579.


Precision detection of liver metastasis by collagen-targeted protein MRI contrast agent.

Salarian M, Yang H, Turaga RC, Tan S, Qiao J, Xue S, Gui Z, Peng G, Han H, Mittal P, Grossniklaus HE, Yang JJ.

Biomaterials. 2019 Dec;224:119478. doi: 10.1016/j.biomaterials.2019.119478. Epub 2019 Sep 6.


Melanocytoma of the Conjunctiva: Clinicopathologic Features of Three Cases.

Herwig-Carl MC, Loeffler KU, Grossniklaus HE.

Ocul Oncol Pathol. 2019 Jun;5(4):290-297. doi: 10.1159/000496557. Epub 2019 Mar 18.


International multicentre retrospective cohort study of ocular adnexal marginal zone B-cell lymphoma.

Hindsø TG, Esmaeli B, Holm F, Mikkelsen LH, Rasmussen PK, Coupland SE, Finger PT, Graue GF, Grossniklaus HE, Honavar SG, Khong JJ, McKelvie PA, Mulay K, Sjö LD, Vemuganti GK, Thuro BA, Heegaard S.

Br J Ophthalmol. 2019 Jun 8. pii: bjophthalmol-2019-314008. doi: 10.1136/bjophthalmol-2019-314008. [Epub ahead of print]


Masquerades of Giant Cell Arteritis Evident on Temporal Artery Biopsy.

Micieli JA, Grossniklaus HE, Peragallo JH.

J Clin Rheumatol. 2019 May 21. doi: 10.1097/RHU.0000000000001072. [Epub ahead of print] No abstract available.


Natural killer cells and pigment epithelial-derived factor control the infiltrative and nodular growth of hepatic metastases in an Orthotopic murine model of ocular melanoma.

Jones NM, Yang H, Zhang Q, Morales-Tirado VM, Grossniklaus HE.

BMC Cancer. 2019 May 22;19(1):484. doi: 10.1186/s12885-019-5712-3.


Digital Image Analysis of BAP-1 Accurately Predicts Uveal Melanoma Metastasis.

Stålhammar G, See TRO, Phillips S, Seregard S, Grossniklaus HE.

Transl Vis Sci Technol. 2019 May 6;8(3):11. doi: 10.1167/tvst.8.3.11. eCollection 2019 May.


Are Risk Factors for Growth of Choroidal Nevi Associated With Malignant Transformation? Assessment With a Validated Genomic Biomarker.

Grossniklaus HE, Van Meir EG.

Am J Ophthalmol. 2019 Jul;203:117-118. doi: 10.1016/j.ajo.2019.01.033. Epub 2019 May 18. No abstract available.


Conjunctival Myxoid Lesions: Clinical-Pathologic Multiparametric Analysis, Including Molecular Genetics (An American Ophthalmological Society Thesis).

Milman T, Salomao DR, Ida CM, Capiz Correa DR, Grossniklaus HE, Zhang Q, Hamershock RA, Shields C, Shields JA, Raber I, Rapuano CJ, Patel R, Eagle RC Jr.

Am J Ophthalmol. 2019 Sep;205:115-131. doi: 10.1016/j.ajo.2019.04.027. Epub 2019 May 10.


Pyogenic Granuloma of the Retina: A Case Series.

Ahmad S, Capiz-Correa D, Grossniklaus HE.

Ocul Oncol Pathol. 2019 Apr;5(3):176-181. doi: 10.1159/000492598. Epub 2018 Sep 10.


Expression of immune checkpoint receptors Indoleamine 2,3-dioxygenase and T cell Ig and ITIM domain in metastatic versus nonmetastatic choroidal melanoma.

Stålhammar G, Seregard S, Grossniklaus HE.

Cancer Med. 2019 Jun;8(6):2784-2792. doi: 10.1002/cam4.2167. Epub 2019 Apr 16.


Neurothekeoma of the eye, conjunctiva, and periorbital adnexa: A report of two cases and brief review.

See TRO, Stålhammar G, Grossniklaus HE.

Surv Ophthalmol. 2019 Nov - Dec;64(6):852-857. doi: 10.1016/j.survophthal.2019.04.002. Epub 2019 Apr 9. Review.


Understanding Uveal Melanoma Metastasis to the Liver: The Zimmerman Effect and the Zimmerman Hypothesis.

Grossniklaus HE.

Ophthalmology. 2019 Apr;126(4):483-487. doi: 10.1016/j.ophtha.2018.09.031. No abstract available.


Comparison of histologic findings in age-related macular degeneration with RPE flatmount images.

Zhang Q, Chrenek MA, Bhatia S, Rashid A, Ferdous S, Donaldson KJ, Skelton H, Wu W, See TRO, Jiang Y, Dalal N, Nickerson JM, Grossniklaus HE.

Mol Vis. 2019 Feb 7;25:70-78. eCollection 2019.


Pyogenic granuloma associated with conjunctival epithelial neoplasia: report of nine cases.

Herwig-Carl MC, Grossniklaus HE, Müller PL, Atzrodt L, Loeffler KU, Auw-Haedrich C.

Br J Ophthalmol. 2019 Oct;103(10):1469-1474. doi: 10.1136/bjophthalmol-2018-312960. Epub 2019 Feb 1.


Proceedings of the Association for Research in Vision and Ophthalmology and Champalimaud Foundation Ocular Oncogenesis and Oncology Conference.

Smith JR, Pe'er J, Belfort RN, Cardoso F, Carvajal RD, Carvalho C, Coupland SE, Desjardins L, Francis JH, Gallie BL, Gombos DS, Grossniklaus HE, Heegaard S, Jager MJ, Kaliki S, Ksander BR, Maeurer M, Moreno E, Pulido JS, Ryll B, Singh AD, Zhao J, Parreira A, Wilson DJ, O'Brien JM.

Transl Vis Sci Technol. 2018 Jan 9;8(1):9. doi: 10.1167/tvst.8.1.9. eCollection 2019 Jan.


Conjunctival Squamous Cell Carcinoma with Corneal Stromal Invasion in Presumed Pterygia: A Case Series.

Mendoza PR, Craven CM, Ip MH, Wilson MW, Coroneo MT, Grossniklaus HE.

Ocul Oncol Pathol. 2018 Jun;4(4):240-249. doi: 10.1159/000485425. Epub 2018 Jan 19.


Scleral Thinning after Transscleral Biopsy for Uveal Melanoma Using Lamellar Scleral Flap.

Siegel DT, Szalai E, Wells JR, Grossniklaus HE.

Ocul Oncol Pathol. 2018 Nov;4(6):381-387. doi: 10.1159/000487007. Epub 2018 Feb 23.


Arylsulfonamide 64B Inhibits Hypoxia/HIF-Induced Expression of c-Met and CXCR4 and Reduces Primary Tumor Growth and Metastasis of Uveal Melanoma.

Dong L, You S, Zhang Q, Osuka S, Devi NS, Kaluz S, Ferguson JH, Yang H, Chen G, Wang B, Grossniklaus HE, Van Meir EG.

Clin Cancer Res. 2019 Apr 1;25(7):2206-2218. doi: 10.1158/1078-0432.CCR-18-1368. Epub 2018 Dec 18.


Orbital Lymphoma-An International Multicenter Retrospective Study.

Olsen TG, Holm F, Mikkelsen LH, Rasmussen PK, Coupland SE, Esmaeli B, Finger PT, Graue GF, Grossniklaus HE, Honavar SG, Khong JJ, McKelvie PA, Mulay K, Sjö LD, Vemuganti GK, Thuro BA, Heegaard S.

Am J Ophthalmol. 2019 Mar;199:44-57. doi: 10.1016/j.ajo.2018.11.002. Epub 2018 Nov 10.


Association of Uveal Melanoma Metastatic Rate With Stochastic Mutation Rate and Type of Mutation.

Szalai E, Jiang Y, van Poppelen NM, Jager MJ, de Klein A, Kilic E, Grossniklaus HE.

JAMA Ophthalmol. 2018 Oct 1;136(10):1115-1120. doi: 10.1001/jamaophthalmol.2018.2986.


Distinct Gene Expression Profiles Define Anaplastic Grade in Retinoblastoma.

Hudson LE, Mendoza P, Hudson WH, Ziesel A, Hubbard GB 3rd, Wells J, Dwivedi B, Kowalski J, Seby S, Patel V, Geisert E, Specht C, Grossniklaus HE.

Am J Pathol. 2018 Oct;188(10):2328-2338. doi: 10.1016/j.ajpath.2018.06.013. Epub 2018 Jul 21.


Iris melanoma presenting as childhood glaucoma.

Gapsis BC, Warren NA, Nutaitis MJ, Bonaparte LA, Cooper SL, Ashenafi M, Grossniklaus HE, Magrath GN.

Am J Ophthalmol Case Rep. 2018 May 26;11:56-60. doi: 10.1016/j.ajoc.2018.05.009. eCollection 2018 Sep.


The American Journal of Ophthalmology Will Publish American Ophthalmological Society Theses.

Parrish RK 2nd, Chew EY, Grossniklaus HE.

Am J Ophthalmol. 2018 Jun;190:xiii-xv. doi: 10.1016/j.ajo.2018.03.019. Epub 2018 Apr 11. No abstract available.


Ocular drug delivery targeted by iontophoresis in the suprachoroidal space using a microneedle.

Jung JH, Chiang B, Grossniklaus HE, Prausnitz MR.

J Control Release. 2018 May 10;277:14-22. doi: 10.1016/j.jconrel.2018.03.001. Epub 2018 Mar 2.


Prognostication for Uveal Melanoma: Are Two Tests Better than One?

Bellerive C, Grossniklaus HE, Singh AD.

Ocul Oncol Pathol. 2017 Nov;3(4):301-303. doi: 10.1159/000472153. Epub 2017 Apr 14. No abstract available.


Retinoinvasive Uveal Melanoma: Report of 2 Cases and Review of the Literature.

Gorham JP, Szalai E, Wells JR, Grossniklaus HE.

Ocul Oncol Pathol. 2017 Nov;3(4):292-295. doi: 10.1159/000468940. Epub 2017 Apr 14.


Mechanisms of Optic Nerve Invasion in Primary Choroidal Melanoma.

Szalai E, Wells JR, Grossniklaus HE.

Ocul Oncol Pathol. 2017 Nov;3(4):267-275. doi: 10.1159/000456718. Epub 2017 Apr 5.


BRAF, NRAS, and GNAQ Mutations in Conjunctival Melanocytic Nevi.

Francis JH, Grossniklaus HE, Habib LA, Marr B, Abramson DH, Busam KJ.

Invest Ophthalmol Vis Sci. 2018 Jan 1;59(1):117-121. doi: 10.1167/iovs.17-22517.


Comparative outcomes and toxicities for ruthenium-106 versus palladium-103 in the treatment of choroidal melanoma.

Danish H, Ferris MJ, Balagamwala E, Switchenko JM, Patel KR, Choudhary M, Craven C, Mendoza P, Suh J, Bergstrom C, Grossniklaus HE, M Aaberg T Sr, Singh A, Crocker IR, Khan MK.

Melanoma Res. 2018 Apr;28(2):120-125. doi: 10.1097/CMR.0000000000000420.



Fine HF, Reshef ER, Prenner JL, Shah SP, Grossniklaus HE, Roth DB.

Retina. 2019 Apr;39(4):761-765. doi: 10.1097/IAE.0000000000002007.


An Infrared Dye-Conjugated Virus-like Particle for the Treatment of Primary Uveal Melanoma.

Kines RC, Varsavsky I, Choudhary S, Bhattacharya D, Spring S, McLaughlin R, Kang SJ, Grossniklaus HE, Vavvas D, Monks S, MacDougall JR, de Los Pinos E, Schiller JT.

Mol Cancer Ther. 2018 Feb;17(2):565-574. doi: 10.1158/1535-7163.MCT-17-0953. Epub 2017 Dec 14.


Vimentin Is Required for Lung Adenocarcinoma Metastasis via Heterotypic Tumor Cell-Cancer-Associated Fibroblast Interactions during Collective Invasion.

Richardson AM, Havel LS, Koyen AE, Konen JM, Shupe J, Wiles WG 4th, Martin WD, Grossniklaus HE, Sica G, Gilbert-Ross M, Marcus AI.

Clin Cancer Res. 2018 Jan 15;24(2):420-432. doi: 10.1158/1078-0432.CCR-17-1776. Epub 2017 Dec 5.


Radiologic and Histopathologic Correlation of Different Growth Patterns of Metastatic Uveal Melanoma to the Liver.

Liao A, Mittal P, Lawson DH, Yang JJ, Szalai E, Grossniklaus HE.

Ophthalmology. 2018 Apr;125(4):597-605. doi: 10.1016/j.ophtha.2017.09.029. Epub 2017 Nov 6.


Clinicopathological Features of Ocular Adnexal Mantle-Cell Lymphoma in an International Multicenter Cohort.

Knudsen MKH, Rasmussen PK, Coupland SE, Esmaeli B, Finger PT, Graue GF, Grossniklaus HE, Khong JJ, McKelvie PA, Mulay K, Ralfkiaer E, Sjö LD, Vemuganti GK, Thuro BA, Curtin J, Heegaard S.

JAMA Ophthalmol. 2017 Dec 1;135(12):1367-1374. doi: 10.1001/jamaophthalmol.2017.4810.


Retinal Reactive Astrocytic Tumor (Focal Nodular Gliosis): The Entity Also Known as Vasoproliferative Tumor.

Grossniklaus HE, Lenis TL, Jakobiec FA.

Ocul Oncol Pathol. 2017 Sep;3(3):161-163. doi: 10.1159/000455149. Epub 2017 Jan 26. No abstract available.


Gene Expression Profiling and Heterogeneity of Nonspecific Orbital Inflammation Affecting the Lacrimal Gland.

Rosenbaum JT, Choi D, Harrington CA, Wilson DJ, Grossniklaus HE, Sibley CH, Salek SS, Ng JD, Dailey RA, Steele EA, Hayek B, Craven CM, Edward DP, Maktabi AMY, Al Hussain H, White VA, Dolman PJ, Czyz CN, Foster JA, Harris GJ, Bee YS, Tse DT, Alabiad CR, Dubovy SR, Kazim M, Selva D, Yeatts RP, Korn BS, Kikkawa DO, Silkiss RZ, Sivak-Callcott JA, Stauffer P, Planck SR.

JAMA Ophthalmol. 2017 Nov 1;135(11):1156-1162. doi: 10.1001/jamaophthalmol.2017.3458.


Pathogenesis of Ocular Findings in Congenital Zika Syndrome.

Capiz D, Grossniklaus HE, Yeh S.

JAMA Ophthalmol. 2017 Oct 1;135(10):1077. doi: 10.1001/jamaophthalmol.2017.3285. No abstract available.


Uveal Melanoma Nuclear BRCA1-Associated Protein-1 Immunoreactivity Is an Indicator of Metastasis.

Szalai E, Wells JR, Ward L, Grossniklaus HE.

Ophthalmology. 2018 Feb;125(2):203-209. doi: 10.1016/j.ophtha.2017.07.018. Epub 2017 Aug 18.


Review of periorbital nerve enlargement and biopsy techniques.

Chen VH, Hayek BR, Grossniklaus HE, Wojno TH, Kim HJ.

Orbit. 2017 Oct;36(5):293-297. doi: 10.1080/01676830.2017.1337177. Epub 2017 Aug 18. Review.


A Pharmacodynamic Analysis of Choroidal Neovascularization in a Porcine Model Using Three Targeted Drugs.

Tran J, Craven C, Wabner K, Schmit J, Matter B, Kompella U, Grossniklaus HE, Olsen TW.

Invest Ophthalmol Vis Sci. 2017 Jul 1;58(9):3732-3740. doi: 10.1167/iovs.16-21230.


Updates in ophthalmic pathology.

Mendoza PR, Grossniklaus HE.

Indian J Ophthalmol. 2017 May;65(5):347-353. doi: 10.4103/ijo.IJO_49_16. Review.


Proliferative Vitreoretinopathy in Treated Retinoblastoma.

Hwang CS, Mendoza PR, Wells JR, Grossniklaus HE, Hubbard GB 3rd.

Ophthalmol Retina. 2017 Mar-Apr;1(2):165-172. doi: 10.1016/j.oret.2016.09.009.


Reactive Retinal Astrocytic Tumor (Focal Nodular Gliosis): A Case Report.

Hudson LE, Mendoza PR, Yan J, Grossniklaus HE.

Ocul Oncol Pathol. 2017 Jan;3(1):1-7. doi: 10.1159/000448042. Epub 2016 Aug 18.

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