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Items: 1 to 50 of 104

1.

Light-induced complex formation of bacteriophytochrome RpBphP1 and gene repressor RpPpsR2 probed by SAXS.

Papiz MZ, Bellini D, Evans K, Grossmann JG, Fordham-Skelton T.

FEBS J. 2019 Jun 27. doi: 10.1111/febs.14973. [Epub ahead of print]

PMID:
31243889
2.

The Two-State Prehensile Tail of the Antibacterial Toxin Colicin N.

Johnson CL, Solovyova AS, Hecht O, Macdonald C, Waller H, Grossmann JG, Moore GR, Lakey JH.

Biophys J. 2017 Oct 17;113(8):1673-1684. doi: 10.1016/j.bpj.2017.08.030.

3.

The application of metal artifact reduction (MAR) in CT scans for radiation oncology by monoenergetic extrapolation with a DECT scanner.

Schwahofer A, Bär E, Kuchenbecker S, Grossmann JG, Kachelrieß M, Sterzing F.

Z Med Phys. 2015 Dec;25(4):314-25. doi: 10.1016/j.zemedi.2015.05.004. Epub 2015 Jul 3.

PMID:
26144602
4.

Disease causing mutants of TDP-43 nucleic acid binding domains are resistant to aggregation and have increased stability and half-life.

Austin JA, Wright GS, Watanabe S, Grossmann JG, Antonyuk SV, Yamanaka K, Hasnain SS.

Proc Natl Acad Sci U S A. 2014 Mar 18;111(11):4309-14. doi: 10.1073/pnas.1317317111. Epub 2014 Mar 3.

5.

MR-guidance--a clinical study to evaluate a shuttle- based MR-linac connection to provide MR-guided radiotherapy.

Bostel T, Nicolay NH, Grossmann JG, Mohr A, Delorme S, Echner G, Häring P, Debus J, Sterzing F.

Radiat Oncol. 2014 Jan 9;9:12. doi: 10.1186/1748-717X-9-12.

6.

Structural characterization of gephyrin by AFM and SAXS reveals a mixture of compact and extended states.

Sander B, Tria G, Shkumatov AV, Kim EY, Grossmann JG, Tessmer I, Svergun DI, Schindelin H.

Acta Crystallogr D Biol Crystallogr. 2013 Oct;69(Pt 10):2050-60. doi: 10.1107/S0907444913018714. Epub 2013 Sep 20.

PMID:
24100323
7.

The application of hybrid pixel detectors for in-house SAXS instrumentation with a view to combined chromatographic operation.

Wright GS, Lee HC, Schulze-Briese C, Grossmann JG, Strange RW, Hasnain SS.

J Synchrotron Radiat. 2013 Mar;20(Pt 2):383-5. doi: 10.1107/S0909049513001866. Epub 2013 Feb 7.

PMID:
23412497
8.

Structural insights into the role of domain flexibility in human DNA ligase IV.

Ochi T, Wu Q, Chirgadze DY, Grossmann JG, Bolanos-Garcia VM, Blundell TL.

Structure. 2012 Jul 3;20(7):1212-22. doi: 10.1016/j.str.2012.04.012. Epub 2012 May 31.

9.

DNA binding by the plant-specific NAC transcription factors in crystal and solution: a firm link to WRKY and GCM transcription factors.

Welner DH, Lindemose S, Grossmann JG, Møllegaard NE, Olsen AN, Helgstrand C, Skriver K, Lo Leggio L.

Biochem J. 2012 Jun 15;444(3):395-404. doi: 10.1042/BJ20111742.

PMID:
22455904
10.

Conformational characterization of synapse-associated protein 97 by nuclear magnetic resonance and small-angle X-ray scattering shows compact and elongated forms.

Tully MD, Grossmann JG, Phelan M, Pandelaneni S, Leyland M, Lian LY.

Biochemistry. 2012 Jan 31;51(4):899-908. doi: 10.1021/bi201178v. Epub 2012 Jan 19.

PMID:
22242544
11.

Structure of the cyanobacterial Magnesium Chelatase H subunit determined by single particle reconstruction and small-angle X-ray scattering.

Qian P, Marklew CJ, Viney J, Davison PA, Brindley AA, Söderberg C, Al-Karadaghi S, Bullough PA, Grossmann JG, Hunter CN.

J Biol Chem. 2012 Feb 10;287(7):4946-56. doi: 10.1074/jbc.M111.308239. Epub 2011 Dec 15.

12.

Self-directed assembly and clustering of the cytoplasmic domains of inwardly rectifying Kir2.1 potassium channels on association with PSD-95.

Fomina S, Howard TD, Sleator OK, Golovanova M, O'Ryan L, Leyland ML, Grossmann JG, Collins RF, Prince SM.

Biochim Biophys Acta. 2011 Oct;1808(10):2374-89. doi: 10.1016/j.bbamem.2011.06.021. Epub 2011 Jul 5.

13.
14.

Deriving the ultrastructure of α-crustacyanin using lower-resolution structural and biophysical methods.

Rhys NH, Wang MC, Jowitt TA, Helliwell JR, Grossmann JG, Baldock C.

J Synchrotron Radiat. 2011 Jan;18(1):79-83. doi: 10.1107/S0909049510034977. Epub 2010 Nov 5.

15.

The Structure of the talin head reveals a novel extended conformation of the FERM domain.

Elliott PR, Goult BT, Kopp PM, Bate N, Grossmann JG, Roberts GC, Critchley DR, Barsukov IL.

Structure. 2010 Oct 13;18(10):1289-99. doi: 10.1016/j.str.2010.07.011.

16.

Tail-mediated collapse of HMGB1 is dynamic and occurs via differential binding of the acidic tail to the A and B domains.

Stott K, Watson M, Howe FS, Grossmann JG, Thomas JO.

J Mol Biol. 2010 Nov 12;403(5):706-22. doi: 10.1016/j.jmb.2010.07.045. Epub 2010 Aug 4.

PMID:
20691192
17.

Structural studies of tri-functional human GART.

Welin M, Grossmann JG, Flodin S, Nyman T, Stenmark P, Trésaugues L, Kotenyova T, Johansson I, Nordlund P, Lehtiö L.

Nucleic Acids Res. 2010 Nov;38(20):7308-19. doi: 10.1093/nar/gkq595. Epub 2010 Jul 14.

18.

Digital asymmetric waveform isolation (DAWI) in a digital linear ion trap.

Brancia FL, McCullough B, Entwistle A, Grossmann JG, Ding L.

J Am Soc Mass Spectrom. 2010 Sep;21(9):1530-3. doi: 10.1016/j.jasms.2010.05.003. Epub 2010 May 7.

19.

Structure of a double ubiquitin-like domain in the talin head: a role in integrin activation.

Goult BT, Bouaouina M, Elliott PR, Bate N, Patel B, Gingras AR, Grossmann JG, Roberts GC, Calderwood DA, Critchley DR, Barsukov IL.

EMBO J. 2010 Mar 17;29(6):1069-80. doi: 10.1038/emboj.2010.4. Epub 2010 Feb 11.

20.

Shape and flexibility in the titin 11-domain super-repeat.

Tskhovrebova L, Walker ML, Grossmann JG, Khan GN, Baron A, Trinick J.

J Mol Biol. 2010 Apr 9;397(4):1092-105. doi: 10.1016/j.jmb.2010.01.073. Epub 2010 Feb 6.

PMID:
20138893
21.

Domain motion in cytochrome P450 reductase: conformational equilibria revealed by NMR and small-angle x-ray scattering.

Ellis J, Gutierrez A, Barsukov IL, Huang WC, Grossmann JG, Roberts GC.

J Biol Chem. 2009 Dec 25;284(52):36628-37. doi: 10.1074/jbc.M109.054304. Epub 2009 Oct 26.

22.

An oligomeric signaling platform formed by the Toll-like receptor signal transducers MyD88 and IRAK-4.

Motshwene PG, Moncrieffe MC, Grossmann JG, Kao C, Ayaluru M, Sandercock AM, Robinson CV, Latz E, Gay NJ.

J Biol Chem. 2009 Sep 11;284(37):25404-11. doi: 10.1074/jbc.M109.022392. Epub 2009 Jul 10.

23.

Role of dimerization and substrate exclusion in the regulation of bone morphogenetic protein-1 and mammalian tolloid.

Berry R, Jowitt TA, Ferrand J, Roessle M, Grossmann JG, Canty-Laird EG, Kammerer RA, Kadler KE, Baldock C.

Proc Natl Acad Sci U S A. 2009 May 26;106(21):8561-6. doi: 10.1073/pnas.0812178106. Epub 2009 May 8.

24.

Digital ion trap mass spectrometer for probing the structure of biological macromolecules by gas phase X-ray scattering.

McCullough BJ, Entwistle A, Konishi I, Buffey S, Hasnain SS, Brancia FL, Grossmann JG, Gaskell SJ.

Anal Chem. 2009 May 1;81(9):3392-7. doi: 10.1021/ac802662d.

PMID:
19354287
25.

Structural determinants of integrin binding to the talin rod.

Gingras AR, Ziegler WH, Bobkov AA, Joyce MG, Fasci D, Himmel M, Rothemund S, Ritter A, Grossmann JG, Patel B, Bate N, Goult BT, Emsley J, Barsukov IL, Roberts GC, Liddington RC, Ginsberg MH, Critchley DR.

J Biol Chem. 2009 Mar 27;284(13):8866-76. doi: 10.1074/jbc.M805937200. Epub 2009 Jan 27.

26.

The crystal structure of the N-terminal region of BUB1 provides insight into the mechanism of BUB1 recruitment to kinetochores.

Bolanos-Garcia VM, Kiyomitsu T, D'Arcy S, Chirgadze DY, Grossmann JG, Matak-Vinkovic D, Venkitaraman AR, Yanagida M, Robinson CV, Blundell TL.

Structure. 2009 Jan 14;17(1):105-16. doi: 10.1016/j.str.2008.10.015.

27.

Assembly of oligomeric death domain complexes during Toll receptor signaling.

Moncrieffe MC, Grossmann JG, Gay NJ.

J Biol Chem. 2008 Nov 28;283(48):33447-54. doi: 10.1074/jbc.M805427200. Epub 2008 Oct 1.

28.

Structural insights into P-glycoprotein (ABCB1) by small angle X-ray scattering and electron crystallography.

McDevitt CA, Shintre CA, Grossmann JG, Pollock NL, Prince SM, Callaghan R, Ford RC.

FEBS Lett. 2008 Aug 20;582(19):2950-6. doi: 10.1016/j.febslet.2008.07.022. Epub 2008 Jul 25.

29.

Characterization of the tetratricopeptide-containing domain of BUB1, BUBR1, and PP5 proves that domain amphiphilicity over amino acid sequence specificity governs protein adsorption and interfacial activity.

Beaufils S, Grossmann JG, Renault A, Bolanos-Garcia VM.

J Phys Chem B. 2008 Jul 10;112(27):7984-91. doi: 10.1021/jp711222s. Epub 2008 Jun 12.

PMID:
18547097
30.

Knotted fusion proteins reveal unexpected possibilities in protein folding.

Mallam AL, Onuoha SC, Grossmann JG, Jackson SE.

Mol Cell. 2008 Jun 6;30(5):642-8. doi: 10.1016/j.molcel.2008.03.019.

31.

Structural studies on the co-chaperone Hop and its complexes with Hsp90.

Onuoha SC, Coulstock ET, Grossmann JG, Jackson SE.

J Mol Biol. 2008 Jun 13;379(4):732-44. doi: 10.1016/j.jmb.2008.02.013. Epub 2008 Feb 14.

PMID:
18485364
32.

Complementing structural information of modular proteins with small angle neutron scattering and contrast variation.

Grossmann JG, Callaghan AJ, Marcaida MJ, Luisi BF, Alcock FH, Tokatlidis K, Moulin M, Haertlein M, Timmins P.

Eur Biophys J. 2008 Jun;37(5):603-11. doi: 10.1007/s00249-008-0278-z. Epub 2008 Feb 13. Erratum in: Eur Biophys J. 2008 Jun;37(5):719. Moulin, M [added]; Haertlein, M [added]; Timmins, P [added].

PMID:
18270693
33.

Identification of quaternary structure and functional domains of the CI repressor from bacteriophage TP901-1.

Pedersen M, Lo Leggio L, Grossmann JG, Larsen S, Hammer K.

J Mol Biol. 2008 Feb 29;376(4):983-96. doi: 10.1016/j.jmb.2007.12.022. Epub 2007 Dec 15.

PMID:
18191944
34.

The structure of the C-terminal actin-binding domain of talin.

Gingras AR, Bate N, Goult BT, Hazelwood L, Canestrelli I, Grossmann JG, Liu H, Putz NS, Roberts GC, Volkmann N, Hanein D, Barsukov IL, Critchley DR.

EMBO J. 2008 Jan 23;27(2):458-69. Epub 2007 Dec 20.

35.

Small-angle X-ray scattering and NMR studies of the conformation of the PDZ region of SAP97 and its interactions with Kir2.1.

Goult BT, Rapley JD, Dart C, Kitmitto A, Grossmann JG, Leyland ML, Lian LY.

Biochemistry. 2007 Dec 11;46(49):14117-28. Epub 2007 Nov 16.

PMID:
18004877
36.

Insights into the structure and domain flexibility of full-length pro-matrix metalloproteinase-9/gelatinase B.

Rosenblum G, Van den Steen PE, Cohen SR, Grossmann JG, Frenkel J, Sertchook R, Slack N, Strange RW, Opdenakker G, Sagi I.

Structure. 2007 Oct;15(10):1227-36.

37.

Conserved substrate binding by chaperones in the bacterial periplasm and the mitochondrial intermembrane space.

Alcock FH, Grossmann JG, Gentle IE, Likić VA, Lithgow T, Tokatlidis K.

Biochem J. 2008 Jan 15;409(2):377-87.

PMID:
17894549
38.

Effect of PEGylation on the solution conformation of antibody fragments.

Lu Y, Harding SE, Turner A, Smith B, Athwal DS, Grossmann JG, Davis KG, Rowe AJ.

J Pharm Sci. 2008 Jun;97(6):2062-79.

PMID:
17828753
39.

Genomic analysis reveals widespread occurrence of new classes of copper nitrite reductases.

Ellis MJ, Grossmann JG, Eady RR, Hasnain SS.

J Biol Inorg Chem. 2007 Nov;12(8):1119-27. Epub 2007 Aug 22.

PMID:
17712582
40.

Solution conformation of wild-type and mutant IgG3 and IgG4 immunoglobulins using crystallohydrodynamics: possible implications for complement activation.

Lu Y, Harding SE, Michaelsen TE, Longman E, Davis KG, Ortega A, Grossmann JG, Sandlie I, García de la Torre J.

Biophys J. 2007 Dec 1;93(11):3733-44. Epub 2007 Aug 17.

41.

Quaternary structures of tumor suppressor p53 and a specific p53 DNA complex.

Tidow H, Melero R, Mylonas E, Freund SM, Grossmann JG, Carazo JM, Svergun DI, Valle M, Fersht AR.

Proc Natl Acad Sci U S A. 2007 Jul 24;104(30):12324-9. Epub 2007 Jul 9.

42.

Structural and conformational analysis of scorpion (Buthus sindicus) hemocyanin using low resolution techniques.

Ali SA, Grossmann JG, Abbasi A, Voelter W.

Protein Pept Lett. 2007;14(5):481-8.

PMID:
17584175
43.

Conformational dynamics and the energetics of protein--ligand interactions: role of interdomain loop in human cytochrome P450 reductase.

Grunau A, Geraki K, Grossmann JG, Gutierrez A.

Biochemistry. 2007 Jul 17;46(28):8244-55. Epub 2007 Jun 20.

PMID:
17580970
44.

Collagen organization in canine myxomatous mitral valve disease: an x-ray diffraction study.

Hadian M, Corcoran BM, Han RI, Grossmann JG, Bradshaw JP.

Biophys J. 2007 Oct 1;93(7):2472-6. Epub 2007 Jun 8.

45.

X-ray- and neutron-scattering studies of alpha-crystallin and evidence that the target protein sits in the fenestrations of the alpha-crystallin shell.

Regini JW, Grossmann JG, Timmins P, Harding JJ, Quantock AJ, Hodson SA, Elliott GF.

Invest Ophthalmol Vis Sci. 2007 Jun;48(6):2695-700.

PMID:
17525201
46.

Structure and drug release in a crosslinked poly(ethylene oxide) hydrogel.

Shekunov BY, Chattopadhyay P, Tong HH, Chow AH, Grossmann JG.

J Pharm Sci. 2007 May;96(5):1320-30.

PMID:
17455363
47.

Modular structure of the full-length DNA gyrase B subunit revealed by small-angle X-ray scattering.

Costenaro L, Grossmann JG, Ebel C, Maxwell A.

Structure. 2007 Mar;15(3):329-39.

48.

Structural basis for protein-protein interactions in the 14-3-3 protein family.

Yang X, Lee WH, Sobott F, Papagrigoriou E, Robinson CV, Grossmann JG, Sundström M, Doyle DA, Elkins JM.

Proc Natl Acad Sci U S A. 2006 Nov 14;103(46):17237-42. Epub 2006 Nov 3.

49.

Small-angle X-ray scattering reveals the solution structure of a bacteriophytochrome in the catalytically active Pr state.

Evans K, Grossmann JG, Fordham-Skelton AP, Papiz MZ.

J Mol Biol. 2006 Dec 8;364(4):655-66. Epub 2006 Sep 23.

PMID:
17027028
50.

Nanostructure of fibrillin-1 reveals compact conformation of EGF arrays and mechanism for extensibility.

Baldock C, Siegler V, Bax DV, Cain SA, Mellody KT, Marson A, Haston JL, Berry R, Wang MC, Grossmann JG, Roessle M, Kielty CM, Wess TJ.

Proc Natl Acad Sci U S A. 2006 Aug 8;103(32):11922-7. Epub 2006 Jul 31.

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