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Items: 28

1.

AKT1E17K Activates Focal Adhesion Kinase and Promotes Melanoma Brain Metastasis.

Kircher DA, Trombetti KA, Silvis MR, Parkman GL, Fischer GM, Angel SN, Stehn CM, Strain SC, Grossmann AH, Duffy KL, Boucher KM, McMahon M, Davies MA, Mendoza MC, VanBrocklin MW, Holmen SL.

Mol Cancer Res. 2019 Sep;17(9):1787-1800. doi: 10.1158/1541-7786.MCR-18-1372. Epub 2019 May 28.

PMID:
31138602
2.

The Small GTPase ARF6 Activates PI3K in Melanoma to Induce a Prometastatic State.

Yoo JH, Brady SW, Acosta-Alvarez L, Rogers A, Peng J, Sorensen LK, Wolff RK, Mleynek T, Shin D, Rich CP, Kircher DA, Bild A, Odelberg SJ, Li DY, Holmen SL, Grossmann AH.

Cancer Res. 2019 Jun 1;79(11):2892-2908. doi: 10.1158/0008-5472.CAN-18-3026. Epub 2019 May 2.

PMID:
31048499
3.

MicroRNA-155 coordinates the immunological landscape within murine melanoma and correlates with immunity in human cancers.

Ekiz HA, Huffaker TB, Grossmann AH, Stephens WZ, Williams MA, Round JL, O'Connell RM.

JCI Insight. 2019 Mar 21;4(6). pii: 126543. doi: 10.1172/jci.insight.126543. eCollection 2019 Mar 21.

4.

Activated MEK cooperates with Cdkn2a and Pten loss to promote the development and maintenance of melanoma.

Yang H, Kircher DA, Kim KH, Grossmann AH, VanBrocklin MW, Holmen SL, Robinson JP.

Oncogene. 2017 Jul 6;36(27):3842-3851. doi: 10.1038/onc.2016.526. Epub 2017 Mar 6.

5.

The small GTPase ARF6 regulates protein trafficking to control cellular function during development and in disease.

Grossmann AH, Zhao H, Jenkins N, Zhu W, Richards JR, Yoo JH, Winter JM, Rich B, Mleynek TM, Li DY, Odelberg SJ.

Small GTPases. 2019 Jan;10(1):1-12. doi: 10.1080/21541248.2016.1259710. Epub 2016 Dec 21.

6.

ARF6 Is an Actionable Node that Orchestrates Oncogenic GNAQ Signaling in Uveal Melanoma.

Yoo JH, Shi DS, Grossmann AH, Sorensen LK, Tong Z, Mleynek TM, Rogers A, Zhu W, Richards JR, Winter JM, Zhu J, Dunn C, Bajji A, Shenderovich M, Mueller AL, Woodman SE, Harbour JW, Thomas KR, Odelberg SJ, Ostanin K, Li DY.

Cancer Cell. 2016 Jun 13;29(6):889-904. doi: 10.1016/j.ccell.2016.04.015. Epub 2016 Jun 2.

7.

AKT1 Activation Promotes Development of Melanoma Metastases.

Cho JH, Robinson JP, Arave RA, Burnett WJ, Kircher DA, Chen G, Davies MA, Grossmann AH, VanBrocklin MW, McMahon M, Holmen SL.

Cell Rep. 2015 Nov 3;13(5):898-905. doi: 10.1016/j.celrep.2015.09.057. Epub 2015 Oct 22.

8.

β-catenin stabilization enhances SS18-SSX2-driven synovial sarcomagenesis and blocks the mesenchymal to epithelial transition.

Barrott JJ, Illum BE, Jin H, Zhu JF, Mosbruger T, Monument MJ, Smith-Fry K, Cable MG, Wang Y, Grossmann AH, Capecchi MR, Jones KB.

Oncotarget. 2015 Sep 8;6(26):22758-66.

9.

Molecular Confirmation of Ewing Sarcoma in an 85-Year-Old Woman.

Monument MJ, Grossmann AH, Baker CC, Randall RL, Liu T, Albertson DJ.

Int J Surg Pathol. 2015 Sep;23(6):500-4. doi: 10.1177/1066896915591584. Epub 2015 Jun 26.

PMID:
26116579
10.

The BRAF kinase domain promotes the development of gliomas in vivo.

Shin CH, Grossmann AH, Holmen SL, Robinson JP.

Genes Cancer. 2015 Jan;6(1-2):9-18.

11.

Evaluation of somatic mutations in tibial pseudarthrosis samples in neurofibromatosis type 1.

Sant DW, Margraf RL, Stevenson DA, Grossmann AH, Viskochil DH, Hanson H, Everitt MD, Rios JJ, Elefteriou F, Hennessey T, Mao R.

J Med Genet. 2015 Apr;52(4):256-61. doi: 10.1136/jmedgenet-2014-102815. Epub 2015 Jan 22.

PMID:
25612910
12.

Strategy for identifying repurposed drugs for the treatment of cerebral cavernous malformation.

Gibson CC, Zhu W, Davis CT, Bowman-Kirigin JA, Chan AC, Ling J, Walker AE, Goitre L, Delle Monache S, Retta SF, Shiu YT, Grossmann AH, Thomas KR, Donato AJ, Lesniewski LA, Whitehead KJ, Li DY.

Circulation. 2015 Jan 20;131(3):289-99. doi: 10.1161/CIRCULATIONAHA.114.010403. Epub 2014 Dec 8.

13.

Dance well: partnering with reference laboratories for oncology testing.

Grossmann AH, Samowitz W, Cohen M.

Arch Pathol Lab Med. 2015 May;139(5):585-6. doi: 10.5858/arpa.2014-0023-ED. Epub 2014 Sep 23. Review. No abstract available.

PMID:
25248093
14.

Molecular dissection of the mechanism by which EWS/FLI expression compromises actin cytoskeletal integrity and cell adhesion in Ewing sarcoma.

Chaturvedi A, Hoffman LM, Jensen CC, Lin YC, Grossmann AH, Randall RL, Lessnick SL, Welm AL, Beckerle MC.

Mol Biol Cell. 2014 Sep 15;25(18):2695-709. doi: 10.1091/mbc.E14-01-0007. Epub 2014 Jul 23.

15.

Detection of gene rearrangements in targeted clinical next-generation sequencing.

Abel HJ, Al-Kateb H, Cottrell CE, Bredemeyer AJ, Pritchard CC, Grossmann AH, Wallander ML, Pfeifer JD, Lockwood CM, Duncavage EJ.

J Mol Diagn. 2014 Jul;16(4):405-17. doi: 10.1016/j.jmoldx.2014.03.006. Epub 2014 May 9.

16.

Severe liver and skin toxicity after radiation and vemurafenib in metastatic melanoma.

Anker CJ, Ribas A, Grossmann AH, Chen X, Narra KK, Akerley W, Andtbacka RH, Noyes RD, Shrieve DC, Grossmann KF.

J Clin Oncol. 2013 Jun 10;31(17):e283-7. doi: 10.1200/JCO.2012.44.7755. Epub 2013 May 6. No abstract available.

PMID:
23650406
17.

The small GTPase ARF6 stimulates β-catenin transcriptional activity during WNT5A-mediated melanoma invasion and metastasis.

Grossmann AH, Yoo JH, Clancy J, Sorensen LK, Sedgwick A, Tong Z, Ostanin K, Rogers A, Grossmann KF, Tripp SR, Thomas KR, D'Souza-Schorey C, Odelberg SJ, Li DY.

Sci Signal. 2013 Mar 5;6(265):ra14. doi: 10.1126/scisignal.2003398.

18.

Interleukin receptor activates a MYD88-ARNO-ARF6 cascade to disrupt vascular stability.

Zhu W, London NR, Gibson CC, Davis CT, Tong Z, Sorensen LK, Shi DS, Guo J, Smith MC, Grossmann AH, Thomas KR, Li DY.

Nature. 2012 Dec 13;492(7428):252-5. doi: 10.1038/nature11603. Epub 2012 Nov 11.

19.

Atypical intradermal smooth muscle neoplasms (formerly cutaneous leiomyosarcomas): case series, immunohistochemical profile and review of the literature.

Hall BJ, Grossmann AH, Webber NP, Ward RA, Tripp SR, Rosenthal HG, Florell SR, Randall RL, Cockerell CJ, Layfield LJ, Liu T.

Appl Immunohistochem Mol Morphol. 2013 Mar;21(2):132-8. doi: 10.1097/PAI.0b013e31825f4af2. Review.

PMID:
22820664
20.

Molecular testing in malignant melanoma.

Grossmann AH, Grossmann KF, Wallander ML.

Diagn Cytopathol. 2012 Jun;40(6):503-10. doi: 10.1002/dc.22810. Review.

PMID:
22619125
21.

Classification, molecular characterization, and the significance of pten alteration in leiomyosarcoma.

Grossmann AH, Layfield LJ, Randall RL.

Sarcoma. 2012;2012:380896. doi: 10.1155/2012/380896. Epub 2012 Feb 15.

22.

Microsatellites with macro-influence in ewing sarcoma.

Monument MJ, Johnson KM, Grossmann AH, Schiffman JD, Randall RL, Lessnick SL.

Genes (Basel). 2012 Jul 23;3(3):444-60. doi: 10.3390/genes3030444.

23.

Epidermal growth factor receptor pathway mutations and colorectal cancer therapy.

Grossmann AH, Samowitz WS.

Arch Pathol Lab Med. 2011 Oct;135(10):1278-82. doi: 10.5858/arpa.2011-0047-RA. Review.

PMID:
21970483
24.

Fine-needle aspiration diagnosis of an intraosseous amyloidoma.

Factor RE, Layfield LJ, Grossmann AH, Crim JR, Price SL, Randall RL.

Diagn Cytopathol. 2012 Aug;40 Suppl 2:E114-7. doi: 10.1002/dc.21686. Epub 2011 May 4.

PMID:
21548115
25.

Mutations in 2 distinct genetic pathways result in cerebral cavernous malformations in mice.

Chan AC, Drakos SG, Ruiz OE, Smith AC, Gibson CC, Ling J, Passi SF, Stratman AN, Sacharidou A, Revelo MP, Grossmann AH, Diakos NA, Davis GE, Metzstein MM, Whitehead KJ, Li DY.

J Clin Invest. 2011 May;121(5):1871-81. doi: 10.1172/JCI44393. Epub 2011 Apr 1. Erratum in: J Clin Invest. 2012 May 1;122(5):1948.

26.

Metastatic pancreatic adenocarcinoma presenting as a large pelvic mass mimicking primary osteogenic sarcoma: a series of two patient cases.

Webber NP, Sharma S, Grossmann AH, Shaaban A, Jones KB, Layfield LJ, Randall RL.

J Clin Oncol. 2010 Oct 10;28(29):e545-9. doi: 10.1200/JCO.2010.28.6153. Epub 2010 Aug 16. No abstract available.

27.

Catalytic domains of tyrosine kinases determine the phosphorylation sites within c-Cbl.

Grossmann AH, Kolibaba KS, Willis SG, Corbin AS, Langdon WS, Deininger MW, Druker BJ.

FEBS Lett. 2004 Nov 19;577(3):555-62.

28.

Maternal effect for DNA mismatch repair in the mouse.

Gurtu VE, Verma S, Grossmann AH, Liskay RM, Skarnes WC, Baker SM.

Genetics. 2002 Jan;160(1):271-7.

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