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Items: 1 to 50 of 192

1.

Epileptic seizures and outcome in different subtypes of subarachnoid haemorrhage - Results of a single-center retrospective analysis.

Wittstock M, Kurtieiev K, Grossmann A, Storch A, Walter U.

J Clin Neurosci. 2019 Aug 16. pii: S0967-5868(19)31170-1. doi: 10.1016/j.jocn.2019.08.055. [Epub ahead of print]

PMID:
31427240
2.

Ring-Expansion Approaches for the Total Synthesis of Salimabromide.

Schmid M, Grossmann AS, Mayer P, Müller T, Magauer T.

Tetrahedron. 2019 Jun 14;75(24):3195-3215. doi: 10.1016/j.tet.2019.03.010. Epub 2019 Mar 9.

PMID:
31160829
3.

AKT1E17K Activates Focal Adhesion Kinase and Promotes Melanoma Brain Metastasis.

Kircher DA, Trombetti KA, Silvis MR, Parkman GL, Fischer GM, Angel SN, Stehn CM, Strain SC, Grossmann AH, Duffy KL, Boucher KM, McMahon M, Davies MA, Mendoza MC, VanBrocklin MW, Holmen SL.

Mol Cancer Res. 2019 Sep;17(9):1787-1800. doi: 10.1158/1541-7786.MCR-18-1372. Epub 2019 May 28.

PMID:
31138602
4.

The Small GTPase ARF6 Activates PI3K in Melanoma to Induce a Prometastatic State.

Yoo JH, Brady SW, Acosta-Alvarez L, Rogers A, Peng J, Sorensen LK, Wolff RK, Mleynek T, Shin D, Rich CP, Kircher DA, Bild A, Odelberg SJ, Li DY, Holmen SL, Grossmann AH.

Cancer Res. 2019 Jun 1;79(11):2892-2908. doi: 10.1158/0008-5472.CAN-18-3026. Epub 2019 May 2.

PMID:
31048499
5.

Correction: The prognostic value of neurofilament levels in patients with sepsis-associated encephalopathy - A prospective, pilot observational study.

Ehler J, Petzold A, Wittstock M, Kolbaske S, Gloger M, Henschel J, Heslegrave A, Zetterberg H, Lunn MP, Rommer PS, Grossmann A, Sharshar T, Richter G, Nöldge-Schomburg G, Sauer M.

PLoS One. 2019 Feb 20;14(2):e0212830. doi: 10.1371/journal.pone.0212830. eCollection 2019.

6.

NF1 Somatic Mutation in Dystrophic Scoliosis.

Margraf RL, VanSant-Webb C, Mao R, Viskochil DH, Carey J, Hanson H, D'Astous J, Grossmann A, Stevenson DA.

J Mol Neurosci. 2019 May;68(1):11-18. doi: 10.1007/s12031-019-01277-0. Epub 2019 Feb 18.

PMID:
30778836
7.

MicroRNA-155 coordinates the immunological landscape within murine melanoma and correlates with immunity in human cancers.

Ekiz HA, Huffaker TB, Grossmann AH, Stephens WZ, Williams MA, Round JL, O'Connell RM.

JCI Insight. 2019 Mar 21;4(6). pii: 126543. doi: 10.1172/jci.insight.126543. eCollection 2019 Mar 21.

8.

The prognostic value of neurofilament levels in patients with sepsis-associated encephalopathy - A prospective, pilot observational study.

Ehler J, Petzold A, Wittstock M, Kolbaske S, Gloger M, Henschel J, Heslegrave A, Zetterberg H, Lunn MP, Rommer PS, Grossmann A, Sharshar T, Richter G, Nöldge-Schomburg G, Sauer M.

PLoS One. 2019 Jan 24;14(1):e0211184. doi: 10.1371/journal.pone.0211184. eCollection 2019. Erratum in: PLoS One. 2019 Feb 20;14(2):e0212830.

9.

Diagnostic value of NT-proCNP compared to NSE and S100B in cerebrospinal fluid and plasma of patients with sepsis-associated encephalopathy.

Ehler J, Saller T, Wittstock M, Rommer PS, Chappell D, Zwissler B, Grossmann A, Richter G, Reuter DA, Nöldge-Schomburg G, Sauer M.

Neurosci Lett. 2019 Jan 23;692:167-173. doi: 10.1016/j.neulet.2018.11.014. Epub 2018 Nov 10.

PMID:
30423400
10.

Total Synthesis of Salimabromide: A Tetracyclic Polyketide from a Marine Myxobacterium.

Schmid M, Grossmann AS, Wurst K, Magauer T.

J Am Chem Soc. 2018 Jul 11;140(27):8444-8447. doi: 10.1021/jacs.8b06228. Epub 2018 Jul 2.

11.

Synthesis, chemical behavior, structure elucidation and iNOS inhibitory activity of 1-substituted 3-methylsulfanyl-5,6,7,8-tetrahydro-1H-[1,2,4]triazolo[1,2-a]pyridazines.

Schulz U, Grossmann A, Wilde F, Freitag M, Lemmerhirt C, Schulzke C, Link A, Morgenstern O.

Pharmazie. 2017 Jul 3;72(7):371-382. doi: 10.1691/ph.2017.6902.

PMID:
29441933
12.

Paracrine osteoprotegerin and β-catenin stabilization support synovial sarcomagenesis in periosteal cells.

Barrott JJ, Illum BE, Jin H, Hedberg ML, Wang Y, Grossmann A, Haldar M, Capecchi MR, Jones KB.

J Clin Invest. 2018 Jan 2;128(1):207-218. doi: 10.1172/JCI94955. Epub 2017 Nov 20.

13.

Translational evidence for two distinct patterns of neuroaxonal injury in sepsis: a longitudinal, prospective translational study.

Ehler J, Barrett LK, Taylor V, Groves M, Scaravilli F, Wittstock M, Kolbaske S, Grossmann A, Henschel J, Gloger M, Sharshar T, Chretien F, Gray F, Nöldge-Schomburg G, Singer M, Sauer M, Petzold A.

Crit Care. 2017 Oct 23;21(1):262. doi: 10.1186/s13054-017-1850-7.

14.

Defining Human Tyrosine Kinase Phosphorylation Networks Using Yeast as an In Vivo Model Substrate.

Corwin T, Woodsmith J, Apelt F, Fontaine JF, Meierhofer D, Helmuth J, Grossmann A, Andrade-Navarro MA, Ballif BA, Stelzl U.

Cell Syst. 2017 Aug 23;5(2):128-139.e4. doi: 10.1016/j.cels.2017.08.001.

15.

Activated MEK cooperates with Cdkn2a and Pten loss to promote the development and maintenance of melanoma.

Yang H, Kircher DA, Kim KH, Grossmann AH, VanBrocklin MW, Holmen SL, Robinson JP.

Oncogene. 2017 Jul 6;36(27):3842-3851. doi: 10.1038/onc.2016.526. Epub 2017 Mar 6.

16.

The small GTPase ARF6 regulates protein trafficking to control cellular function during development and in disease.

Grossmann AH, Zhao H, Jenkins N, Zhu W, Richards JR, Yoo JH, Winter JM, Rich B, Mleynek TM, Li DY, Odelberg SJ.

Small GTPases. 2019 Jan;10(1):1-12. doi: 10.1080/21541248.2016.1259710. Epub 2016 Dec 21.

17.

Neuromyelitis optica spectrum disorder coinciding with hematological immune disease: A case report.

Patejdl R, Wittstock M, Zettl UK, Jost K, Grossmann A, Prudlo J.

Mult Scler Relat Disord. 2016 Sep;9:101-3. doi: 10.1016/j.msard.2016.07.006. Epub 2016 Jul 8.

PMID:
27645353
18.

Erectile function after treatment for rhabdomyosarcoma of prostate and bladder.

Frees S, Rubenwolf P, Ziesel C, Faber J, Gutjahr P, Grossmann A, Thüroff JW, Stein R.

J Pediatr Urol. 2016 Dec;12(6):404.e1-404.e6. doi: 10.1016/j.jpurol.2016.07.002. Epub 2016 Aug 1.

PMID:
27570092
19.

Rapid Access to Orthogonally Functionalized Naphthalenes: Application to the Total Synthesis of the Anticancer Agent Chartarin.

Unzner TA, Grossmann AS, Magauer T.

Angew Chem Int Ed Engl. 2016 Aug 8;55(33):9763-7. doi: 10.1002/anie.201605071. Epub 2016 Jun 29.

PMID:
27355517
20.

Long-term outcome after urinary diversion using the ileocecal segment in children and adolescents: Complications of the efferent segment.

Deuker M, Roos FC, Großmann A, Faé P, Thüroff JW, Stein R.

J Pediatr Urol. 2016 Aug;12(4):247.e1-7. doi: 10.1016/j.jpurol.2016.05.008. Epub 2016 May 25.

PMID:
27282550
21.

ARF6 Is an Actionable Node that Orchestrates Oncogenic GNAQ Signaling in Uveal Melanoma.

Yoo JH, Shi DS, Grossmann AH, Sorensen LK, Tong Z, Mleynek TM, Rogers A, Zhu W, Richards JR, Winter JM, Zhu J, Dunn C, Bajji A, Shenderovich M, Mueller AL, Woodman SE, Harbour JW, Thomas KR, Odelberg SJ, Ostanin K, Li DY.

Cancer Cell. 2016 Jun 13;29(6):889-904. doi: 10.1016/j.ccell.2016.04.015. Epub 2016 Jun 2.

22.

Trihaloethenes as versatile building blocks for organic synthesis.

Grossmann AS, Magauer T.

Org Biomol Chem. 2016 Jun 15;14(24):5377-89. doi: 10.1039/c6ob00091f. Review.

PMID:
27181133
23.

AKT1 Activation Promotes Development of Melanoma Metastases.

Cho JH, Robinson JP, Arave RA, Burnett WJ, Kircher DA, Chen G, Davies MA, Grossmann AH, VanBrocklin MW, McMahon M, Holmen SL.

Cell Rep. 2015 Nov 3;13(5):898-905. doi: 10.1016/j.celrep.2015.09.057. Epub 2015 Oct 22.

24.

Magnetic resonance-transcranial ultrasound fusion imaging: A novel tool for brain electrode location.

Walter U, Müller JU, Rösche J, Kirsch M, Grossmann A, Benecke R, Wittstock M, Wolters A.

Mov Disord. 2016 Mar;31(3):302-9. doi: 10.1002/mds.26425. Epub 2015 Sep 12.

PMID:
26362398
25.

β-catenin stabilization enhances SS18-SSX2-driven synovial sarcomagenesis and blocks the mesenchymal to epithelial transition.

Barrott JJ, Illum BE, Jin H, Zhu JF, Mosbruger T, Monument MJ, Smith-Fry K, Cable MG, Wang Y, Grossmann AH, Capecchi MR, Jones KB.

Oncotarget. 2015 Sep 8;6(26):22758-66.

26.

Ring Opening of Bicyclo[3.1.0]hexan-2-ones: A Versatile Synthetic Platform for the Construction of Substituted Benzoates.

Feierfeil J, Grossmann A, Magauer T.

Angew Chem Int Ed Engl. 2015 Sep 28;54(40):11835-8. doi: 10.1002/anie.201506232. Epub 2015 Aug 7.

PMID:
26255867
27.

Molecular Confirmation of Ewing Sarcoma in an 85-Year-Old Woman.

Monument MJ, Grossmann AH, Baker CC, Randall RL, Liu T, Albertson DJ.

Int J Surg Pathol. 2015 Sep;23(6):500-4. doi: 10.1177/1066896915591584. Epub 2015 Jun 26.

PMID:
26116579
28.

[Perampanel in the treatment of a patient with glioblastoma multiforme without IDH1 mutation and without MGMT promotor methylation].

Rösche J, Piek J, Hildebrandt G, Grossmann A, Kirschstein T, Benecke R.

Fortschr Neurol Psychiatr. 2015 May;83(5):286-9. doi: 10.1055/s-0034-1399459. Epub 2015 May 27. German.

PMID:
26018396
29.

The orthopedic diseases of ancient Egypt.

Fritsch KO, Hamoud H, Allam AH, Grossmann A, Nur El-Din AH, Abdel-Maksoud G, Soliman MA, Badr I, Sutherland JD, Sutherland ML, Akl M, Finch CE, Thomas GS, Wann LS, Thompson RC.

Anat Rec (Hoboken). 2015 Jun;298(6):1036-46. doi: 10.1002/ar.23136.

30.

Enantioselective Synthesis of Chromanones via a Peptidic Phosphane Catalyzed Rauhut-Currier Reaction.

Scanes RJ, Grossmann O, Grossmann A, Spring DR.

Org Lett. 2015 May 15;17(10):2462-5. doi: 10.1021/acs.orglett.5b00971. Epub 2015 Apr 27.

PMID:
25915565
31.

The BRAF kinase domain promotes the development of gliomas in vivo.

Shin CH, Grossmann AH, Holmen SL, Robinson JP.

Genes Cancer. 2015 Jan;6(1-2):9-18.

32.

Phospho-tyrosine dependent protein-protein interaction network.

Grossmann A, Benlasfer N, Birth P, Hegele A, Wachsmuth F, Apelt L, Stelzl U.

Mol Syst Biol. 2015 Mar 26;11(3):794. doi: 10.15252/msb.20145968.

33.

[Continent urinary diversion following anterior exenteration].

Stein R, Kamal MG, Rubenwolf P, Großmann A, Thomas C, Thüroff JW.

Urologe A. 2015 Mar;54(3):359-67. doi: 10.1007/s00120-014-3684-0. German.

PMID:
25733310
34.

Evaluation of somatic mutations in tibial pseudarthrosis samples in neurofibromatosis type 1.

Sant DW, Margraf RL, Stevenson DA, Grossmann AH, Viskochil DH, Hanson H, Everitt MD, Rios JJ, Elefteriou F, Hennessey T, Mao R.

J Med Genet. 2015 Apr;52(4):256-61. doi: 10.1136/jmedgenet-2014-102815. Epub 2015 Jan 22.

PMID:
25612910
35.

Strategy for identifying repurposed drugs for the treatment of cerebral cavernous malformation.

Gibson CC, Zhu W, Davis CT, Bowman-Kirigin JA, Chan AC, Ling J, Walker AE, Goitre L, Delle Monache S, Retta SF, Shiu YT, Grossmann AH, Thomas KR, Donato AJ, Lesniewski LA, Whitehead KJ, Li DY.

Circulation. 2015 Jan 20;131(3):289-99. doi: 10.1161/CIRCULATIONAHA.114.010403. Epub 2014 Dec 8.

36.

Modeling alveolar soft part sarcomagenesis in the mouse: a role for lactate in the tumor microenvironment.

Goodwin ML, Jin H, Straessler K, Smith-Fry K, Zhu JF, Monument MJ, Grossmann A, Randall RL, Capecchi MR, Jones KB.

Cancer Cell. 2014 Dec 8;26(6):851-862. doi: 10.1016/j.ccell.2014.10.003. Epub 2014 Nov 26.

37.

Diversity-oriented synthesis of drug-like macrocyclic scaffolds using an orthogonal organo- and metal catalysis strategy.

Grossmann A, Bartlett S, Janecek M, Hodgkinson JT, Spring DR.

Angew Chem Int Ed Engl. 2014 Nov 24;53(48):13093-7. doi: 10.1002/anie.201406865. Epub 2014 Sep 26.

PMID:
25257387
38.

Dance well: partnering with reference laboratories for oncology testing.

Grossmann AH, Samowitz W, Cohen M.

Arch Pathol Lab Med. 2015 May;139(5):585-6. doi: 10.5858/arpa.2014-0023-ED. Epub 2014 Sep 23. Review. No abstract available.

PMID:
25248093
39.

Molecular dissection of the mechanism by which EWS/FLI expression compromises actin cytoskeletal integrity and cell adhesion in Ewing sarcoma.

Chaturvedi A, Hoffman LM, Jensen CC, Lin YC, Grossmann AH, Randall RL, Lessnick SL, Welm AL, Beckerle MC.

Mol Biol Cell. 2014 Sep 15;25(18):2695-709. doi: 10.1091/mbc.E14-01-0007. Epub 2014 Jul 23.

40.

Progressive multifocal leukoencephalopathy in a patient with pre-clinical primary biliary cirrhosis.

Meister S, Benecke R, König FB, Großmann A, Zettl UK, Winkelmann A.

Clin Neurol Neurosurg. 2014 Aug;123:45-9. doi: 10.1016/j.clineuro.2014.04.032. Epub 2014 May 10. No abstract available.

PMID:
25012010
41.

Detection of gene rearrangements in targeted clinical next-generation sequencing.

Abel HJ, Al-Kateb H, Cottrell CE, Bredemeyer AJ, Pritchard CC, Grossmann AH, Wallander ML, Pfeifer JD, Lockwood CM, Duncavage EJ.

J Mol Diagn. 2014 Jul;16(4):405-17. doi: 10.1016/j.jmoldx.2014.03.006. Epub 2014 May 9.

42.

Asymmetric synthesis of pyrroloindolones by N-heterocyclic carbene catalyzed [2+3] annulation of α-chloroaldehydes with nitrovinylindoles.

Ni Q, Zhang H, Grossmann A, Loh CC, Merkens C, Enders D.

Angew Chem Int Ed Engl. 2013 Dec 16;52(51):13562-6. doi: 10.1002/anie.201305957. Epub 2013 Nov 4.

PMID:
24346939
43.

N-heterocyclic-carbene-catalyzed one-pot synthesis of hydroxamic esters.

Song X, Ni Q, Grossmann A, Enders D.

Chem Asian J. 2013 Dec;8(12):2965-9. doi: 10.1002/asia.201300938. Epub 2013 Sep 11. No abstract available.

PMID:
24027246
44.

Disappearance of breach rhythm heralding recurrent tumor progression in a patient with astrocytoma.

Kampf C, Grossmann A, Benecke R, Rösche J.

Clin EEG Neurosci. 2013 Jul;44(3):237-43. doi: 10.1177/1550059412458263.

PMID:
23820313
45.

Clinical, genetic, and brain sonographic features related to Parkinson's disease in Gaucher disease.

Böttcher T, Rolfs A, Meyer B, Grossmann A, Berg D, Kropp P, Benecke R, Walter U.

J Neurol. 2013 Oct;260(10):2523-31. doi: 10.1007/s00415-013-7011-2. Epub 2013 Jun 29.

PMID:
23811968
46.

Investigations on synthesis and structure elucidation of novel [1,2,4]triazolo[1,2-a]pyridazine-1-thiones and their inhibitory activity against inducible nitric oxide synthase.

Schulz U, Grossmann A, Witetschek M, Lemmerhirt C, Polzin M, Haertel B, Wanka H, Morgenstern O.

Bioorg Med Chem. 2013 Sep 1;21(17):5518-31. doi: 10.1016/j.bmc.2013.05.064. Epub 2013 Jun 12.

PMID:
23810674
47.

Severe liver and skin toxicity after radiation and vemurafenib in metastatic melanoma.

Anker CJ, Ribas A, Grossmann AH, Chen X, Narra KK, Akerley W, Andtbacka RH, Noyes RD, Shrieve DC, Grossmann KF.

J Clin Oncol. 2013 Jun 10;31(17):e283-7. doi: 10.1200/JCO.2012.44.7755. Epub 2013 May 6. No abstract available.

PMID:
23650406
48.

Sonographic detection of basal ganglia abnormalities in spasmodic dysphonia.

Walter U, Blitzer A, Benecke R, Grossmann A, Dressler D.

Eur J Neurol. 2014 Feb;21(2):349-52. doi: 10.1111/ene.12151. Epub 2013 Apr 14.

PMID:
23581276
49.

Effects of intranasal oxytocin on the neural basis of face processing in autism spectrum disorder.

Domes G, Heinrichs M, Kumbier E, Grossmann A, Hauenstein K, Herpertz SC.

Biol Psychiatry. 2013 Aug 1;74(3):164-71. doi: 10.1016/j.biopsych.2013.02.007. Epub 2013 Mar 16.

PMID:
23510581
50.

The small GTPase ARF6 stimulates β-catenin transcriptional activity during WNT5A-mediated melanoma invasion and metastasis.

Grossmann AH, Yoo JH, Clancy J, Sorensen LK, Sedgwick A, Tong Z, Ostanin K, Rogers A, Grossmann KF, Tripp SR, Thomas KR, D'Souza-Schorey C, Odelberg SJ, Li DY.

Sci Signal. 2013 Mar 5;6(265):ra14. doi: 10.1126/scisignal.2003398.

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