Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 24

1.

Cancer expression quantitative trait loci (eQTLs) can be determined from heterogeneous tumor gene expression data by modeling variation in tumor purity.

Geeleher P, Nath A, Wang F, Zhang Z, Barbeira AN, Fessler J, Grossman RL, Seoighe C, Stephanie Huang R.

Genome Biol. 2018 Sep 11;19(1):130. doi: 10.1186/s13059-018-1507-0.

2.

Data Harmonization for a Molecularly Driven Health System.

Lee JS, Kibbe WA, Grossman RL.

Cell. 2018 Aug 23;174(5):1045-1048. doi: 10.1016/j.cell.2018.08.012.

3.

Progress Toward Cancer Data Ecosystems.

Grossman RL.

Cancer J. 2018 May/Jun;24(3):126-130. doi: 10.1097/PPO.0000000000000318.

PMID:
29794537
4.

Developing Cancer Informatics Applications and Tools Using the NCI Genomic Data Commons API.

Wilson S, Fitzsimons M, Ferguson M, Heath A, Jensen M, Miller J, Murphy MW, Porter J, Sahni H, Staudt L, Tang Y, Wang Z, Yu C, Zhang J, Ferretti V, Grossman RL; GDC Project.

Cancer Res. 2017 Nov 1;77(21):e15-e18. doi: 10.1158/0008-5472.CAN-17-0598.

5.

The medical science DMZ: a network design pattern for data-intensive medical science.

Peisert S, Dart E, Barnett W, Balas E, Cuff J, Grossman RL, Berman A, Shankar A, Tierney B.

J Am Med Inform Assoc. 2017 Oct 6. doi: 10.1093/jamia/ocx104. [Epub ahead of print]

PMID:
29040639
6.

A Case for Data Commons: Toward Data Science as a Service.

Grossman RL, Heath A, Murphy M, Patterson M, Wells W.

Comput Sci Eng. 2016 Sep-Oct;18(5):10-20. doi: 10.1109/MCSE.2016.92. Epub 2016 Aug 24.

8.

Discovering novel pharmacogenomic biomarkers by imputing drug response in cancer patients from large genomics studies.

Geeleher P, Zhang Z, Wang F, Gruener RF, Nath A, Morrison G, Bhutra S, Grossman RL, Huang RS.

Genome Res. 2017 Oct;27(10):1743-1751. doi: 10.1101/gr.221077.117. Epub 2017 Aug 28.

9.

The NCI Genomic Data Commons as an engine for precision medicine.

Jensen MA, Ferretti V, Grossman RL, Staudt LM.

Blood. 2017 Jul 27;130(4):453-459. doi: 10.1182/blood-2017-03-735654. Epub 2017 Jun 9. Review.

10.

Collaborating to Compete: Blood Profiling Atlas in Cancer (BloodPAC) Consortium.

Grossman RL, Abel B, Angiuoli S, Barrett JC, Bassett D, Bramlett K, Blumenthal GM, Carlsson A, Cortese R, DiGiovanna J, Davis-Dusenbery B, Dittamore R, Eberhard DA, Febbo P, Fitzsimons M, Flamig Z, Godsey J, Goswami J, Gruen A, Ortuño F, Han J, Hayes D, Hicks J, Holloway D, Hovelson D, Johnson J, Juhl H, Kalamegham R, Kamal R, Kang Q, Kelloff GJ, Klozenbuecher M, Kolatkar A, Kuhn P, Langone K, Leary R, Loverso P, Manmathan H, Martin AM, Martini J, Miller D, Mitchell M, Morgan T, Mulpuri R, Nguyen T, Otto G, Pathak A, Peters E, Philip R, Posadas E, Reese D, Reese MG, Robinson D, Dei Rossi A, Sakul H, Schageman J, Singh S, Scher HI, Schmitt K, Silvestro A, Simmons J, Simmons T, Sislow J, Talasaz A, Tang P, Tewari M, Tomlins S, Toukhy H, Tseng HR, Tuck M, Tzou A, Vinson J, Wang Y, Wells W, Welsh A, Wilbanks J, Wolf J, Young L, Lee J, Leiman LC.

Clin Pharmacol Ther. 2017 May;101(5):589-592. doi: 10.1002/cpt.666. Epub 2017 Apr 12. Review.

11.

Toward a Shared Vision for Cancer Genomic Data.

Grossman RL, Heath AP, Ferretti V, Varmus HE, Lowy DR, Kibbe WA, Staudt LM.

N Engl J Med. 2016 Sep 22;375(12):1109-12. doi: 10.1056/NEJMp1607591. No abstract available.

PMID:
27653561
12.

The Medical Science DMZ.

Peisert S, Barnett W, Dart E, Cuff J, Grossman RL, Balas E, Berman A, Shankar A, Tierney B.

J Am Med Inform Assoc. 2016 Nov;23(6):1199-1201. doi: 10.1093/jamia/ocw032. Epub 2016 May 2.

13.

Diverse patterns of genomic targeting by transcriptional regulators in Drosophila melanogaster.

Slattery M, Ma L, Spokony RF, Arthur RK, Kheradpour P, Kundaje A, Nègre N, Crofts A, Ptashkin R, Zieba J, Ostapenko A, Suchy S, Victorsen A, Jameel N, Grundstad AJ, Gao W, Moran JR, Rehm EJ, Grossman RL, Kellis M, White KP.

Genome Res. 2014 Jul;24(7):1224-35. doi: 10.1101/gr.168807.113.

14.

Bionimbus: a cloud for managing, analyzing and sharing large genomics datasets.

Heath AP, Greenway M, Powell R, Spring J, Suarez R, Hanley D, Bandlamudi C, McNerney ME, White KP, Grossman RL.

J Am Med Inform Assoc. 2014 Nov-Dec;21(6):969-75. doi: 10.1136/amiajnl-2013-002155. Epub 2014 Jan 24.

15.

A nondegenerate code of deleterious variants in Mendelian loci contributes to complex disease risk.

Blair DR, Lyttle CS, Mortensen JM, Bearden CF, Jensen AB, Khiabanian H, Melamed R, Rabadan R, Bernstam EV, Brunak S, Jensen LJ, Nicolae D, Shah NH, Grossman RL, Cox NJ, White KP, Rzhetsky A.

Cell. 2013 Sep 26;155(1):70-80. doi: 10.1016/j.cell.2013.08.030.

16.

Comparison of the genome sequences of "Candidatus Portiera aleyrodidarum" primary endosymbionts of the whitefly Bemisia tabaci B and Q biotypes.

Jiang ZF, Xia F, Johnson KW, Brown CD, Bartom E, Tuteja JH, Stevens R, Grossman RL, Brumin M, White KP, Ghanim M.

Appl Environ Microbiol. 2013 Mar;79(5):1757-9. doi: 10.1128/AEM.02976-12. Epub 2013 Jan 11.

17.

CUX1 is a haploinsufficient tumor suppressor gene on chromosome 7 frequently inactivated in acute myeloid leukemia.

McNerney ME, Brown CD, Wang X, Bartom ET, Karmakar S, Bandlamudi C, Yu S, Ko J, Sandall BP, Stricker T, Anastasi J, Grossman RL, Cunningham JM, Le Beau MM, White KP.

Blood. 2013 Feb 7;121(6):975-83. doi: 10.1182/blood-2012-04-426965. Epub 2012 Dec 3.

18.

Genome sequences of the primary endosymbiont "Candidatus Portiera aleyrodidarum" in the whitefly Bemisia tabaci B and Q biotypes.

Jiang ZF, Xia F, Johnson KW, Bartom E, Tuteja JH, Stevens R, Grossman RL, Brumin M, White KP, Ghanim M.

J Bacteriol. 2012 Dec;194(23):6678-9. doi: 10.1128/JB.01841-12.

19.

A vision for a biomedical cloud.

Grossman RL, White KP.

J Intern Med. 2012 Feb;271(2):122-30. doi: 10.1111/j.1365-2796.2011.02491.x. Review.

20.

A cis-regulatory map of the Drosophila genome.

Nègre N, Brown CD, Ma L, Bristow CA, Miller SW, Wagner U, Kheradpour P, Eaton ML, Loriaux P, Sealfon R, Li Z, Ishii H, Spokony RF, Chen J, Hwang L, Cheng C, Auburn RP, Davis MB, Domanus M, Shah PK, Morrison CA, Zieba J, Suchy S, Senderowicz L, Victorsen A, Bild NA, Grundstad AJ, Hanley D, MacAlpine DM, Mannervik M, Venken K, Bellen H, White R, Gerstein M, Russell S, Grossman RL, Ren B, Posakony JW, Kellis M, White KP.

Nature. 2011 Mar 24;471(7339):527-31. doi: 10.1038/nature09990.

21.

Flynet: a genomic resource for Drosophila melanogaster transcriptional regulatory networks.

Tian F, Shah PK, Liu X, Negre N, Chen J, Karpenko O, White KP, Grossman RL.

Bioinformatics. 2009 Nov 15;25(22):3001-4. doi: 10.1093/bioinformatics/btp469. Epub 2009 Aug 5.

22.

Sector and Sphere: the design and implementation of a high-performance data cloud.

Gu Y, Grossman RL.

Philos Trans A Math Phys Eng Sci. 2009 Jun 28;367(1897):2429-45. doi: 10.1098/rsta.2009.0053.

23.

Taking care of business:.

Grossman RL, Adams FT.

New Solut. 1993 Apr 1;3(3):7-18. doi: 10.2190/NS3.3.c. No abstract available.

PMID:
22913952
24.

The song and dance of the 1990 clean air 'act'.

Grossman RL.

New Solut. 1991 Jan 1;1(3):4-8. doi: 10.2190/NS1.3.b. No abstract available.

PMID:
22910422

Supplemental Content

Loading ...
Support Center