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Items: 1 to 50 of 185

1.

T cell receptor-triggered nuclear actin network formation drives CD4+ T cell effector functions.

Tsopoulidis N, Kaw S, Laketa V, Kutscheidt S, Baarlink C, Stolp B, Grosse R, Fackler OT.

Sci Immunol. 2019 Jan 4;4(31). pii: eaav1987. doi: 10.1126/sciimmunol.aav1987.

PMID:
30610013
2.

Cell type-selective pathways and clinical associations of lysophosphatidic acid biosynthesis and signaling in the ovarian cancer microenvironment.

Reinartz S, Lieber S, Pesek J, Brandt DT, Asafova A, Finkernagel F, Watzer B, Nockher WA, Nist A, Stiewe T, Jansen JM, Wagner U, Konzer A, Graumann J, Grosse R, Worzfeld T, Müller-Brüsselbach S, Müller R.

Mol Oncol. 2018 Oct 23. doi: 10.1002/1878-0261.12396. [Epub ahead of print]

3.

Dynamizing nuclear actin filaments.

Plessner M, Grosse R.

Curr Opin Cell Biol. 2018 Sep 4;56:1-6. doi: 10.1016/j.ceb.2018.08.005. [Epub ahead of print] Review.

4.

Serum ferritin is not a reliable predictor to determine iron overload in thalassemia major patients post-hematopoietic stem cell transplantation.

Jarisch A, Salzmann-Manrique E, Cario H, Grosse R, Soerensen J, Fischer R, Schulz A, Hammerstingl R, Wunderlich A, Bader P.

Eur J Haematol. 2018 Dec;101(6):791-797. doi: 10.1111/ejh.13169. Epub 2018 Oct 25.

PMID:
30187571
5.

[Selenium deficiency in an organic extensive water buffalo farm].

Große R, Binici C, Pieper R, Müller KE.

Tierarztl Prax Ausg G Grosstiere Nutztiere. 2018 Jun;46(3):191-195. doi: 10.15653/TPG-170632. Epub 2018 Jun 14. German.

PMID:
29902819
6.

Interplay of cell-cell contacts and RhoA/MRTF-A signaling regulates cardiomyocyte identity.

Dorn T, Kornherr J, Parrotta EI, Zawada D, Ayetey H, Santamaria G, Iop L, Mastantuono E, Sinnecker D, Goedel A, Dirschinger RJ, My I, Laue S, Bozoglu T, Baarlink C, Ziegler T, Graf E, Hinkel R, Cuda G, Kääb S, Grace AA, Grosse R, Kupatt C, Meitinger T, Smith AG, Laugwitz KL, Moretti A.

EMBO J. 2018 Jun 15;37(12). pii: e98133. doi: 10.15252/embj.201798133. Epub 2018 May 15.

7.

A Rac1-FMNL2 signaling module affects cell-cell contact formation independent of Cdc42 and membrane protrusions.

Grobe H, Wüstenhagen A, Baarlink C, Grosse R, Grikscheit K.

PLoS One. 2018 Mar 26;13(3):e0194716. doi: 10.1371/journal.pone.0194716. eCollection 2018.

8.

Mitochondrial rescue prevents glutathione peroxidase-dependent ferroptosis.

Jelinek A, Heyder L, Daude M, Plessner M, Krippner S, Grosse R, Diederich WE, Culmsee C.

Free Radic Biol Med. 2018 Mar;117:45-57. doi: 10.1016/j.freeradbiomed.2018.01.019. Epub 2018 Jan 31.

PMID:
29378335
9.

A transient pool of nuclear F-actin at mitotic exit controls chromatin organization.

Baarlink C, Plessner M, Sherrard A, Morita K, Misu S, Virant D, Kleinschnitz EM, Harniman R, Alibhai D, Baumeister S, Miyamoto K, Endesfelder U, Kaidi A, Grosse R.

Nat Cell Biol. 2017 Dec;19(12):1389-1399. doi: 10.1038/ncb3641. Epub 2017 Nov 13.

PMID:
29131140
10.

MRTF transcription and Ezrin-dependent plasma membrane blebbing are required for entotic invasion.

Hinojosa LS, Holst M, Baarlink C, Grosse R.

J Cell Biol. 2017 Oct 2;216(10):3087-3095. doi: 10.1083/jcb.201702010. Epub 2017 Aug 3.

11.

Immunosuppression in Honeybee Queens by the Neonicotinoids Thiacloprid and Clothianidin.

Brandt A, Grikscheit K, Siede R, Grosse R, Meixner MD, Büchler R.

Sci Rep. 2017 Jul 5;7(1):4673. doi: 10.1038/s41598-017-04734-1.

12.

Correction: Actin visualization at a glance.

Melak M, Plessner M, Grosse R.

J Cell Sci. 2017 May 1;130(9):1688. doi: 10.1242/jcs.204487. No abstract available.

13.

The epidemiology of sickle cell disease in Germany following recent large-scale immigration.

Kunz JB, Cario H, Grosse R, Jarisch A, Lobitz S, Kulozik AE.

Pediatr Blood Cancer. 2017 Jul;64(7). doi: 10.1002/pbc.26550. Epub 2017 Apr 6.

PMID:
28383793
14.

Actin visualization at a glance.

Melak M, Plessner M, Grosse R.

J Cell Sci. 2017 Feb 1;130(3):525-530. doi: 10.1242/jcs.189068. Epub 2017 Jan 12. Review. Erratum in: J Cell Sci. 2017 May 1;130(9):1688.

15.

Building a National Framework for Adolescent and Young Adult Hematology and Oncology and Transition from Pediatric to Adult Care: Report of the Inaugural Meeting of the "AjET" Working Group of the German Society for Pediatric Oncology and Hematology.

Escherich G, Bielack S, Maier S, Braungart R, Brümmendorf TH, Freund M, Grosse R, Hoferer A, Kampschulte R, Koch B, Lauten M, Milani V, Ross H, Schilling F, Wöhrle D, Cario H, Dirksen U.

J Adolesc Young Adult Oncol. 2017 Jun;6(2):194-199. doi: 10.1089/jayao.2016.0075. Epub 2016 Dec 16.

PMID:
27983882
16.

Mutant p53 promotes tumor progression and metastasis by the endoplasmic reticulum UDPase ENTPD5.

Vogiatzi F, Brandt DT, Schneikert J, Fuchs J, Grikscheit K, Wanzel M, Pavlakis E, Charles JP, Timofeev O, Nist A, Mernberger M, Kantelhardt EJ, Siebolts U, Bartel F, Jacob R, Rath A, Moll R, Grosse R, Stiewe T.

Proc Natl Acad Sci U S A. 2016 Dec 27;113(52):E8433-E8442. doi: 10.1073/pnas.1612711114. Epub 2016 Dec 12.

17.

SCAI promotes DNA double-strand break repair in distinct chromosomal contexts.

Hansen RK, Mund A, Poulsen SL, Sandoval M, Klement K, Tsouroula K, Tollenaere MA, Räschle M, Soria R, Offermanns S, Worzfeld T, Grosse R, Brandt DT, Rozell B, Mann M, Cole F, Soutoglou E, Goodarzi AA, Daniel JA, Mailand N, Bekker-Jensen S.

Nat Cell Biol. 2016 Dec;18(12):1357-1366. doi: 10.1038/ncb3436. Epub 2016 Nov 7.

18.

Memory and Spatial Cognition in Breast Cancer Patients Undergoing Adjuvant Endocrine Therapy.

Berndt U, Leplow B, Schoenfeld R, Lantzsch T, Grosse R, Thomssen C.

Breast Care (Basel). 2016 Aug;11(4):240-246. Epub 2016 Jun 28.

19.

Analysis of a cohort of 101 CDAII patients: description of 24 new molecular variants and genotype-phenotype correlations.

Bianchi P, Schwarz K, Högel J, Fermo E, Vercellati C, Grosse R, van Wijk R, van Zwieten R, Barcellini W, Zanella A, Heimpel H.

Br J Haematol. 2016 Nov;175(4):696-704. doi: 10.1111/bjh.14271. Epub 2016 Jul 29.

PMID:
27471141
20.

Left atrial active contractile function parameters assessed by cardiac MR are sensitive to myocardial iron.

Wehbe MS, Yamamura J, Fischer R, Grosse R, Berliner C, Graessner J, Lund G, Adam G, Schoennagel BP.

J Magn Reson Imaging. 2017 Feb;45(2):535-541. doi: 10.1002/jmri.25396. Epub 2016 Jul 26.

PMID:
27459111
21.

Peak Filling Rates Assessed by CMR Imaging Indicate Diastolic Dysfunction From Myocardial Iron Toxicity.

Schoennagel BP, Fischer R, Grosse R, Berliner C, Wehbe M, Kurio G, Lund G, Wang ZJ, Graessner J, Adam G, Yamamura J.

JACC Cardiovasc Imaging. 2016 Nov;9(11):1353-1354. doi: 10.1016/j.jcmg.2015.10.017. Epub 2016 Jan 6. No abstract available.

22.

Formins at the Junction.

Grikscheit K, Grosse R.

Trends Biochem Sci. 2016 Feb;41(2):148-159. doi: 10.1016/j.tibs.2015.12.002. Epub 2015 Dec 28. Review.

PMID:
26732401
23.

Filamin A interacts with the coactivator MKL1 to promote the activity of the transcription factor SRF and cell migration.

Kircher P, Hermanns C, Nossek M, Drexler MK, Grosse R, Fischer M, Sarikas A, Penkava J, Lewis T, Prywes R, Gudermann T, Muehlich S.

Sci Signal. 2015 Nov 10;8(402):ra112. doi: 10.1126/scisignal.aad2959.

PMID:
26554816
24.

Diagnosis of pathological complete response to neoadjuvant chemotherapy in breast cancer by minimal invasive biopsy techniques.

Heil J, Kümmel S, Schaefgen B, Paepke S, Thomssen C, Rauch G, Ataseven B, Große R, Dreesmann V, Kühn T, Loibl S, Blohmer JU, von Minckwitz G.

Br J Cancer. 2015 Dec 1;113(11):1565-70. doi: 10.1038/bjc.2015.381. Epub 2015 Nov 10.

25.

The Prevalence of Sickle Cell Disease and Its Implication for Newborn Screening in Germany (Hamburg Metropolitan Area).

Grosse R, Lukacs Z, Cobos PN, Oyen F, Ehmen C, Muntau B, Timmann C, Noack B.

Pediatr Blood Cancer. 2016 Jan;63(1):168-70. doi: 10.1002/pbc.25706. Epub 2015 Aug 14.

PMID:
26275168
26.

Formin-like 2 Promotes β1-Integrin Trafficking and Invasive Motility Downstream of PKCα.

Wang Y, Arjonen A, Pouwels J, Ta H, Pausch P, Bange G, Engel U, Pan X, Fackler OT, Ivaska J, Grosse R.

Dev Cell. 2015 Aug 24;34(4):475-83. doi: 10.1016/j.devcel.2015.06.015. Epub 2015 Aug 6.

27.

Extracellular signaling cues for nuclear actin polymerization.

Plessner M, Grosse R.

Eur J Cell Biol. 2015 Jul-Sep;94(7-9):359-62. doi: 10.1016/j.ejcb.2015.05.009. Epub 2015 Jun 1. Review.

PMID:
26059398
28.

Junctional actin assembly is mediated by Formin-like 2 downstream of Rac1.

Grikscheit K, Frank T, Wang Y, Grosse R.

J Cell Biol. 2015 May 11;209(3):367-76. doi: 10.1083/jcb.201412015.

29.

Nuclear F-actin formation and reorganization upon cell spreading.

Plessner M, Melak M, Chinchilla P, Baarlink C, Grosse R.

J Biol Chem. 2015 May 1;290(18):11209-16. doi: 10.1074/jbc.M114.627166. Epub 2015 Mar 10.

30.

LOV is all we need.

Grosse R.

Nat Rev Mol Cell Biol. 2015 Apr;16(4):206. doi: 10.1038/nrm3950. Epub 2015 Jan 29. No abstract available.

PMID:
25630916
31.

Brain iron quantification by MRI in mitochondrial membrane protein-associated neurodegeneration under iron-chelating therapy.

Löbel U, Schweser F, Nickel M, Deistung A, Grosse R, Hagel C, Fiehler J, Schulz A, Hartig M, Reichenbach JR, Kohlschütter A, Sedlacik J.

Ann Clin Transl Neurol. 2014 Dec;1(12):1041-6. doi: 10.1002/acn3.116. Epub 2014 Dec 2.

32.

Pancreatic iron and fat assessment by MRI-R2* in patients with iron overload diseases.

Pfeifer CD, Schoennagel BP, Grosse R, Wang ZJ, Graessner J, Nielsen P, Adam G, Fischer R, Yamamura J.

J Magn Reson Imaging. 2015 Jul;42(1):196-203. doi: 10.1002/jmri.24752. Epub 2014 Sep 19.

PMID:
25236606
33.

Mechanisms of plasma non-transferrin bound iron generation: insights from comparing transfused diamond blackfan anaemia with sickle cell and thalassaemia patients.

Porter JB, Walter PB, Neumayr LD, Evans P, Bansal S, Garbowski M, Weyhmiller MG, Harmatz PR, Wood JC, Miller JL, Byrnes C, Weiss G, Seifert M, Grosse R, Grabowski D, Schmidt A, Fischer R, Nielsen P, Niemeyer C, Vichinsky E.

Br J Haematol. 2014 Dec;167(5):692-6. doi: 10.1111/bjh.13081. Epub 2014 Sep 11.

34.

G-protein-coupled receptor signaling and polarized actin dynamics drive cell-in-cell invasion.

Purvanov V, Holst M, Khan J, Baarlink C, Grosse R.

Elife. 2014 Jun 20;3. doi: 10.7554/eLife.02786.

35.

Formin' actin in the nucleus.

Baarlink C, Grosse R.

Nucleus. 2014 Jan-Feb;5(1):15-20. doi: 10.4161/nucl.28066. Epub 2014 Feb 3.

36.

Dynamics of Gαq-protein-p63RhoGEF interaction and its regulation by RGS2.

Bodmann EL, Rinne A, Brandt D, Lutz S, Wieland T, Grosse R, Bünemann M.

Biochem J. 2014 Feb 15;458(1):131-40. doi: 10.1042/BJ20130782.

PMID:
24299002
37.

Pharmacological inhibition of actin assembly to target tumor cell motility.

Nürnberg A, Kollmannsperger A, Grosse R.

Rev Physiol Biochem Pharmacol. 2014;166:23-42. doi: 10.1007/112_2013_16. Review.

PMID:
24193252
38.

To be or not to be assembled: progressing into nuclear actin filaments.

Grosse R, Vartiainen MK.

Nat Rev Mol Cell Biol. 2013 Nov;14(11):693-7. doi: 10.1038/nrm3681. Epub 2013 Oct 3. Review.

PMID:
24088744
39.

Functional interaction of SCAI with the SWI/SNF complex for transcription and tumor cell invasion.

Kreßner C, Nollau P, Grosse R, Brandt DT.

PLoS One. 2013 Aug 2;8(8):e69947. doi: 10.1371/journal.pone.0069947. Print 2013.

40.

Nuclear actin network assembly by formins regulates the SRF coactivator MAL.

Baarlink C, Wang H, Grosse R.

Science. 2013 May 17;340(6134):864-7. doi: 10.1126/science.1235038. Epub 2013 Apr 4.

41.

Retracted: Pharmacological Inhibition of Actin Assembly to Target Tumor Cell Motility.

Nürnberg A, Kollmannsperger A, Grosse R.

Rev Physiol Biochem Pharmacol. 2013 Mar 20. [Epub ahead of print] No abstract available.

PMID:
23512207
42.

[Iron quantification in iron overload disease using MRI].

Schönnagel BP, Fischer R, Nielsen P, Grosse R, Adam G, Yamamura J.

Rofo. 2013 Jul;185(7):621-7. doi: 10.1055/s-0032-1330721. Epub 2013 Feb 28. Review. German.

43.

Inverse PPARβ/δ agonists suppress oncogenic signaling to the ANGPTL4 gene and inhibit cancer cell invasion.

Adhikary T, Brandt DT, Kaddatz K, Stockert J, Naruhn S, Meissner W, Finkernagel F, Obert J, Lieber S, Scharfe M, Jarek M, Toth PM, Scheer F, Diederich WE, Reinartz S, Grosse R, Müller-Brüsselbach S, Müller R.

Oncogene. 2013 Oct 31;32(44):5241-52. doi: 10.1038/onc.2012.549. Epub 2012 Dec 3.

44.

Administration of recombinant erythropoietin alone does not improve the phenotype in iron refractory iron deficiency anemia patients.

Lehmberg K, Grosse R, Muckenthaler MU, Altamura S, Nielsen P, Schmid H, Graubner U, Oyen F, Zeller W, Schneppenheim R, Janka GE.

Ann Hematol. 2013 Mar;92(3):387-94. doi: 10.1007/s00277-012-1618-8. Epub 2012 Nov 20.

PMID:
23180434
45.

Differing and isoform-specific roles for the formin DIAPH3 in plasma membrane blebbing and filopodia formation.

Stastna J, Pan X, Wang H, Kollmannsperger A, Kutscheidt S, Lohmann V, Grosse R, Fackler OT.

Cell Res. 2012 Apr;22(4):728-45. doi: 10.1038/cr.2011.202. Epub 2011 Dec 20.

46.

Pancreatic exocrine function and cardiac iron in patients with iron overload and with thalassemia.

Yamamura J, Grosse R, Jarisch A, Janka GE, Nielsen P, Adam G, Fischer R.

Pediatr Blood Cancer. 2011 Oct;57(4):674-6. doi: 10.1002/pbc.22990. Epub 2011 Jun 10.

PMID:
21671371
47.

Nucleating actin for invasion.

Nürnberg A, Kitzing T, Grosse R.

Nat Rev Cancer. 2011 Mar;11(3):177-87. doi: 10.1038/nrc3003. Epub 2011 Feb 10. Review.

PMID:
21326322
48.

Adjuvant docetaxel for high-risk, node-negative breast cancer.

Martín M, Seguí MA, Antón A, Ruiz A, Ramos M, Adrover E, Aranda I, Rodríguez-Lescure A, Grosse R, Calvo L, Barnadas A, Isla D, Martinez del Prado P, Ruiz Borrego M, Zaluski J, Arcusa A, Muñoz M, López Vega JM, Mel JR, Munarriz B, Llorca C, Jara C, Alba E, Florián J, Li J, López García-Asenjo JA, Sáez A, Rios MJ, Almenar S, Peiró G, Lluch A; GEICAM 9805 Investigators.

N Engl J Med. 2010 Dec 2;363(23):2200-10. doi: 10.1056/NEJMoa0910320.

49.

Nef does not inhibit F-actin remodelling and HIV-1 cell-cell transmission at the T lymphocyte virological synapse.

Haller C, Tibroni N, Rudolph JM, Grosse R, Fackler OT.

Eur J Cell Biol. 2011 Nov;90(11):913-21. doi: 10.1016/j.ejcb.2010.09.010. Epub 2010 Nov 1.

PMID:
21044805
50.

Distribution of cardiac iron measured by magnetic resonance imaging (MRI)-R*2.

Yamamura J, Grosse R, Graessner J, Janka GE, Adam G, Fischer R.

J Magn Reson Imaging. 2010 Nov;32(5):1104-9. doi: 10.1002/jmri.22364.

PMID:
21031515

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