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Items: 1 to 50 of 509

1.

MRI Is a DNA Damage Response Adaptor during Classical Non-homologous End Joining.

Hung PJ, Johnson B, Chen BR, Byrum AK, Bredemeyer AL, Yewdell WT, Johnson TE, Lee BJ, Deivasigamani S, Hindi I, Amatya P, Gross ML, Paull TT, Pisapia DJ, Chaudhuri J, Petrini JJH, Mosammaparast N, Amarasinghe GK, Zha S, Tyler JK, Sleckman BP.

Mol Cell. 2018 Jul 19;71(2):332-342.e8. doi: 10.1016/j.molcel.2018.06.018. Epub 2018 Jul 12.

PMID:
30017584
2.

Allosteric Coupling of CARMIL and V-1 Binding to Capping Protein Revealed by Hydrogen-Deuterium Exchange.

Johnson B, McConnell P, Kozlov AG, Mekel M, Lohman TM, Gross ML, Amarasinghe GK, Cooper JA.

Cell Rep. 2018 May 29;23(9):2795-2804. doi: 10.1016/j.celrep.2018.04.096.

3.

Implementing fast photochemical oxidation of proteins (FPOP) as a footprinting approach to solve diverse problems in structural biology.

Zhang B, Cheng M, Rempel D, Gross ML.

Methods. 2018 Jul 15;144:94-103. doi: 10.1016/j.ymeth.2018.05.016. Epub 2018 May 23. Review.

PMID:
29800613
4.

Pulsed Hydrogen-Deuterium Exchange Illuminates the Aggregation Kinetics of α-Synuclein, the Causative Agent for Parkinson's Disease.

Illes-Toth E, Rempel DL, Gross ML.

ACS Chem Neurosci. 2018 Jun 20;9(6):1469-1476. doi: 10.1021/acschemneuro.8b00052. Epub 2018 Apr 11.

PMID:
29601177
5.

Human IFIT3 Modulates IFIT1 RNA Binding Specificity and Protein Stability.

Johnson B, VanBlargan LA, Xu W, White JP, Shan C, Shi PY, Zhang R, Adhikari J, Gross ML, Leung DW, Diamond MS, Amarasinghe GK.

Immunity. 2018 Mar 20;48(3):487-499.e5. doi: 10.1016/j.immuni.2018.01.014. Epub 2018 Mar 8.

PMID:
29525521
6.

Mouse and Human Monoclonal Antibodies Protect against Infection by Multiple Genotypes of Japanese Encephalitis Virus.

Fernandez E, Kose N, Edeling MA, Adhikari J, Sapparapu G, Lazarte SM, Nelson CA, Govero J, Gross ML, Fremont DH, Crowe JE Jr, Diamond MS.

MBio. 2018 Feb 27;9(1). pii: e00008-18. doi: 10.1128/mBio.00008-18.

7.

Electron Cryo-microscopy Structure of Ebola Virus Nucleoprotein Reveals a Mechanism for Nucleocapsid-like Assembly.

Su Z, Wu C, Shi L, Luthra P, Pintilie GD, Johnson B, Porter JR, Ge P, Chen M, Liu G, Frederick TE, Binning JM, Bowman GR, Zhou ZH, Basler CF, Gross ML, Leung DW, Chiu W, Amarasinghe GK.

Cell. 2018 Feb 22;172(5):966-978.e12. doi: 10.1016/j.cell.2018.02.009.

8.

Primary and Higher Order Structure of the Reaction Center from the Purple Phototrophic Bacterium Blastochloris viridis: A Test for Native Mass Spectrometry.

Lu Y, Goodson C, Blankenship RE, Gross ML.

J Proteome Res. 2018 Apr 6;17(4):1615-1623. doi: 10.1021/acs.jproteome.7b00897. Epub 2018 Mar 2.

PMID:
29466012
9.

Mass Spectrometry-Based Fast Photochemical Oxidation of Proteins (FPOP) for Higher Order Structure Characterization.

Li KS, Shi L, Gross ML.

Acc Chem Res. 2018 Mar 20;51(3):736-744. doi: 10.1021/acs.accounts.7b00593. Epub 2018 Feb 16.

PMID:
29450991
10.

Reactive oxygen species leave a damage trail that reveals water channels in Photosystem II.

Weisz DA, Gross ML, Pakrasi HB.

Sci Adv. 2017 Nov 17;3(11):eaao3013. doi: 10.1126/sciadv.aao3013. eCollection 2017 Nov.

11.

Understanding Curli Amyloid-Protein Aggregation by Hydrogen-Deuterium Exchange and Mass Spectrometry.

Wang H, Shu Q, Rempel DL, Frieden C, Gross ML.

Int J Mass Spectrom. 2017 Sep;420:16-23. doi: 10.1016/j.ijms.2016.10.006. Epub 2016 Oct 11.

PMID:
29056864
12.

Saving Life, Limb, and Eyesight: Assessing the Medical Rules of Eligibility During Armed Conflict.

Gross ML.

Am J Bioeth. 2017 Oct;17(10):40-52. doi: 10.1080/15265161.2017.1365186.

PMID:
29020561
13.

Response to Open Peer Commentaries on "Saving Life, Limb, and Eyesight: Assessing the Medical Rules of Eligibility During Armed Conflict".

Gross ML.

Am J Bioeth. 2017 Oct;17(10):W1-W3. doi: 10.1080/15265161.2017.1374042. No abstract available.

PMID:
29020552
14.

Laser-Initiated Radical Trifluoromethylation of Peptides and Proteins: Application to Mass-Spectrometry-Based Protein Footprinting.

Cheng M, Zhang B, Cui W, Gross ML.

Angew Chem Int Ed Engl. 2017 Nov 6;56(45):14007-14010. doi: 10.1002/anie.201706697. Epub 2017 Oct 5.

PMID:
28901679
15.

Peptide-Level Interactions between Proteins and Small-Molecule Drug Candidates by Two Hydrogen-Deuterium Exchange MS-Based Methods: The Example of Apolipoprotein E3.

Wang H, Rempel DL, Giblin D, Frieden C, Gross ML.

Anal Chem. 2017 Oct 17;89(20):10687-10695. doi: 10.1021/acs.analchem.7b01121. Epub 2017 Sep 25.

PMID:
28901129
16.

Effect of smoking cessation on quantitative computed tomography in smokers at risk in a lung cancer screening population.

Jobst BJ, Weinheimer O, Trauth M, Becker N, Motsch E, Groß ML, Tremper J, Delorme S, Eigentopf A, Eichinger M, Kauczor HU, Wielpütz MO.

Eur Radiol. 2018 Feb;28(2):807-815. doi: 10.1007/s00330-017-5030-6. Epub 2017 Sep 7.

PMID:
28884215
17.

Native Mass Spectrometry, Ion mobility, and Collision-Induced Unfolding Categorize Malaria Antigen/Antibody Binding.

Huang Y, Salinas ND, Chen E, Tolia NH, Gross ML.

J Am Soc Mass Spectrom. 2017 Nov;28(11):2515-2518. doi: 10.1007/s13361-017-1782-0. Epub 2017 Sep 5.

PMID:
28875466
18.

Hydrogen-Deuterium Exchange Mass Spectrometry Reveals Calcium Binding Properties and Allosteric Regulation of Downstream Regulatory Element Antagonist Modulator (DREAM).

Zhang J, Li J, Craig TA, Kumar R, Gross ML.

Biochemistry. 2017 Jul 18;56(28):3523-3530. doi: 10.1021/acs.biochem.7b00100. Epub 2017 Jul 3.

19.

Orthogonal Mass Spectrometry-Based Footprinting for Epitope Mapping and Structural Characterization: The IL-6 Receptor upon Binding of Protein Therapeutics.

Li KS, Chen G, Mo J, Huang RY, Deyanova EG, Beno BR, O'Neil SR, Tymiak AA, Gross ML.

Anal Chem. 2017 Jul 18;89(14):7742-7749. doi: 10.1021/acs.analchem.7b01748. Epub 2017 Jul 6.

20.

A Molecular Mechanism for Nonphotochemical Quenching in Cyanobacteria.

Lu Y, Liu H, Saer R, Li VL, Zhang H, Shi L, Goodson C, Gross ML, Blankenship RE.

Biochemistry. 2017 Jun 6;56(22):2812-2823. doi: 10.1021/acs.biochem.7b00202. Epub 2017 May 25.

21.

Deamidation Slows Curli Amyloid-Protein Aggregation.

Wang H, Shu Q, Frieden C, Gross ML.

Biochemistry. 2017 Jun 13;56(23):2865-2872. doi: 10.1021/acs.biochem.7b00241. Epub 2017 May 26.

22.

A Focus Honoring R. Graham Cooks' Election to the National Academy of Sciences.

Gross ML.

J Am Soc Mass Spectrom. 2017 Jun;28(6):986-990. doi: 10.1007/s13361-017-1646-7. No abstract available.

23.

Mapping the Binding Interface of VEGF and a Monoclonal Antibody Fab-1 Fragment with Fast Photochemical Oxidation of Proteins (FPOP) and Mass Spectrometry.

Zhang Y, Wecksler AT, Molina P, Deperalta G, Gross ML.

J Am Soc Mass Spectrom. 2017 May;28(5):850-858. doi: 10.1007/s13361-017-1601-7. Epub 2017 Mar 2.

24.

Evolutionary fine-tuning of conformational ensembles in FimH during host-pathogen interactions.

Kalas V, Pinkner JS, Hannan TJ, Hibbing ME, Dodson KW, Holehouse AS, Zhang H, Tolia NH, Gross ML, Pappu RV, Janetka J, Hultgren SJ.

Sci Adv. 2017 Feb 10;3(2):e1601944. doi: 10.1126/sciadv.1601944. eCollection 2017 Feb.

25.

Mass spectrometry-based cross-linking study shows that the Psb28 protein binds to cytochrome b559 in Photosystem II.

Weisz DA, Liu H, Zhang H, Thangapandian S, Tajkhorshid E, Gross ML, Pakrasi HB.

Proc Natl Acad Sci U S A. 2017 Feb 28;114(9):2224-2229. doi: 10.1073/pnas.1620360114. Epub 2017 Feb 13.

26.

Mapping the Energetic Epitope of an Antibody/Interleukin-23 Interaction with Hydrogen/Deuterium Exchange, Fast Photochemical Oxidation of Proteins Mass Spectrometry, and Alanine Shave Mutagenesis.

Li J, Wei H, Krystek SR Jr, Bond D, Brender TM, Cohen D, Feiner J, Hamacher N, Harshman J, Huang RY, Julien SH, Lin Z, Moore K, Mueller L, Noriega C, Sejwal P, Sheppard P, Stevens B, Chen G, Tymiak AA, Gross ML, Schneeweis LA.

Anal Chem. 2017 Feb 21;89(4):2250-2258. doi: 10.1021/acs.analchem.6b03058. Epub 2017 Feb 9.

27.

The proteolysis adaptor, NblA, binds to the N-terminus of β-phycocyanin: Implications for the mechanism of phycobilisome degradation.

Nguyen AY, Bricker WP, Zhang H, Weisz DA, Gross ML, Pakrasi HB.

Photosynth Res. 2017 Apr;132(1):95-106. doi: 10.1007/s11120-016-0334-y. Epub 2017 Jan 11.

28.

Hybrid Methods Reveal Multiple Flexibly Linked DNA Polymerases within the Bacteriophage T7 Replisome.

Wallen JR, Zhang H, Weis C, Cui W, Foster BM, Ho CMW, Hammel M, Tainer JA, Gross ML, Ellenberger T.

Structure. 2017 Jan 3;25(1):157-166. doi: 10.1016/j.str.2016.11.019.

29.

Native Mass Spectrometry Analysis of Oligomerization States of Fluorescence Recovery Protein and Orange Carotenoid Protein: Two Proteins Involved in the Cyanobacterial Photoprotection Cycle.

Lu Y, Liu H, Saer RG, Zhang H, Meyer CM, Li VL, Shi L, King JD, Gross ML, Blankenship RE.

Biochemistry. 2017 Jan 10;56(1):160-166. doi: 10.1021/acs.biochem.6b01094. Epub 2016 Dec 20.

30.

Kinetic Isotope Effects and Hydrogen/Deuterium Exchange Reveal Large Conformational Changes During the Catalysis of the Clostridium acetobutylicum Spore Photoproduct Lyase.

Yang L, Adhikari J, Gross ML, Li L.

Photochem Photobiol. 2017 Jan;93(1):331-342. doi: 10.1111/php.12697. Epub 2017 Jan 30.

31.

Incorporation of a Reporter Peptide in FPOP Compensates for Adventitious Scavengers and Permits Time-Dependent Measurements.

Niu B, Mackness BC, Rempel DL, Zhang H, Cui W, Matthews CR, Zitzewitz JA, Gross ML.

J Am Soc Mass Spectrom. 2017 Feb;28(2):389-392. doi: 10.1007/s13361-016-1552-4. Epub 2016 Dec 6.

32.

Warfarin traps human vitamin K epoxide reductase in an intermediate state during electron transfer.

Shen G, Cui W, Zhang H, Zhou F, Huang W, Liu Q, Yang Y, Li S, Bowman GR, Sadler JE, Gross ML, Li W.

Nat Struct Mol Biol. 2017 Jan;24(1):69-76. doi: 10.1038/nsmb.3333. Epub 2016 Dec 5.

33.

The pH-Dependent Trigger in Diphtheria Toxin T Domain Comes with a Safety Latch.

Rodnin MV, Li J, Gross ML, Ladokhin AS.

Biophys J. 2016 Nov 1;111(9):1946-1953. doi: 10.1016/j.bpj.2016.09.030.

34.

Modelling proteins' hidden conformations to predict antibiotic resistance.

Hart KM, Ho CM, Dutta S, Gross ML, Bowman GR.

Nat Commun. 2016 Oct 6;7:12965. doi: 10.1038/ncomms12965.

35.

Conformational-Sensitive Fast Photochemical Oxidation of Proteins and Mass Spectrometry Characterize Amyloid Beta 1-42 Aggregation.

Li KS, Rempel DL, Gross ML.

J Am Chem Soc. 2016 Sep 21;138(37):12090-8. doi: 10.1021/jacs.6b07543. Epub 2016 Sep 12.

36.

Native Mass Spectrometry Characterizes the Photosynthetic Reaction Center Complex from the Purple Bacterium Rhodobacter sphaeroides.

Zhang H, Harrington LB, Lu Y, Prado M, Saer R, Rempel D, Blankenship RE, Gross ML.

J Am Soc Mass Spectrom. 2017 Jan;28(1):87-95. doi: 10.1007/s13361-016-1451-8. Epub 2016 Aug 9.

37.

Fast Photochemical Oxidation of Proteins Maps the Topology of Intrinsic Membrane Proteins: Light-Harvesting Complex 2 in a Nanodisc.

Lu Y, Zhang H, Niedzwiedzki DM, Jiang J, Blankenship RE, Gross ML.

Anal Chem. 2016 Sep 6;88(17):8827-34. doi: 10.1021/acs.analchem.6b01945. Epub 2016 Aug 16.

38.

Dimerization Controls Marburg Virus VP24-dependent Modulation of Host Antioxidative Stress Responses.

Johnson B, Li J, Adhikari J, Edwards MR, Zhang H, Schwarz T, Leung DW, Basler CF, Gross ML, Amarasinghe GK.

J Mol Biol. 2016 Aug 28;428(17):3483-94. doi: 10.1016/j.jmb.2016.07.020. Epub 2016 Aug 4.

39.

Garasic review, Guantanamo and other cases of enforced medical treatment.

Gross ML.

J Med Ethics. 2017 Jan;43(1):27. doi: 10.1136/medethics-2016-103581. Epub 2016 Jul 5. No abstract available.

PMID:
27381577
40.

The Use of Advanced Mass Spectrometry to Dissect the Life-Cycle of Photosystem II.

Weisz DA, Gross ML, Pakrasi HB.

Front Plant Sci. 2016 May 10;7:617. doi: 10.3389/fpls.2016.00617. eCollection 2016. Review.

41.

Broadly neutralizing epitopes in the Plasmodium vivax vaccine candidate Duffy Binding Protein.

Chen E, Salinas ND, Huang Y, Ntumngia F, Plasencia MD, Gross ML, Adams JH, Tolia NH.

Proc Natl Acad Sci U S A. 2016 May 31;113(22):6277-82. doi: 10.1073/pnas.1600488113. Epub 2016 May 18.

42.

Native MS and ECD Characterization of a Fab-Antigen Complex May Facilitate Crystallization for X-ray Diffraction.

Zhang Y, Cui W, Wecksler AT, Zhang H, Molina P, Deperalta G, Gross ML.

J Am Soc Mass Spectrom. 2016 Jul;27(7):1139-42. doi: 10.1007/s13361-016-1398-9. Epub 2016 Apr 21.

43.

ApoE: In Vitro Studies of a Small Molecule Effector.

Mondal T, Wang H, DeKoster GT, Baban B, Gross ML, Frieden C.

Biochemistry. 2016 May 10;55(18):2613-21. doi: 10.1021/acs.biochem.6b00324. Epub 2016 Apr 27.

44.

Native mass spectrometry and ion mobility characterize the orange carotenoid protein functional domains.

Zhang H, Liu H, Lu Y, Wolf NR, Gross ML, Blankenship RE.

Biochim Biophys Acta. 2016 Jun;1857(6):734-9. doi: 10.1016/j.bbabio.2016.02.015. Epub 2016 Feb 24.

45.

Dramatic Domain Rearrangements of the Cyanobacterial Orange Carotenoid Protein upon Photoactivation.

Liu H, Zhang H, Orf GS, Lu Y, Jiang J, King JD, Wolf NR, Gross ML, Blankenship RE.

Biochemistry. 2016 Feb 23;55(7):1003-9. doi: 10.1021/acs.biochem.6b00013. Epub 2016 Feb 9.

46.

Effect of smoking cessation counseling within a randomised study on early detection of lung cancer in Germany.

Bade M, Bähr V, Brandt U, Eigentopf A, Brüchert T, Gross ML, Motsch E, Becker N.

J Cancer Res Clin Oncol. 2016 May;142(5):959-68. doi: 10.1007/s00432-015-2105-0. Epub 2016 Jan 27.

PMID:
26814889
47.

The psychological effects of cyber terrorism.

Gross ML, Canetti D, Vashdi DR.

Bull At Sci. 2016;72(5):284-291. doi: 10.1080/00963402.2016.1216502. Epub 2016 Aug 4.

48.

Protein Footprinting by Carbenes on a Fast Photochemical Oxidation of Proteins (FPOP) Platform.

Zhang B, Rempel DL, Gross ML.

J Am Soc Mass Spectrom. 2016 Mar;27(3):552-5. doi: 10.1007/s13361-015-1313-9. Epub 2015 Dec 17.

49.

A Dynamic Model of pH-Induced Protein G'e Higher Order Structure Changes derived from Mass Spectrometric Analyses.

Yefremova Y, Al-Majdoub M, Opuni KF, Koy C, Yan Y, Gross ML, Glocker MO.

Anal Chem. 2016 Jan 5;88(1):890-7. doi: 10.1021/acs.analchem.5b03536. Epub 2015 Dec 9.

50.

Top-Down Mass Spectrometry Analysis of Membrane-Bound Light-Harvesting Complex 2 from Rhodobacter sphaeroides.

Lu Y, Zhang H, Cui W, Saer R, Liu H, Gross ML, Blankenship RE.

Biochemistry. 2015 Dec 15;54(49):7261-71. doi: 10.1021/acs.biochem.5b00959. Epub 2015 Dec 2.

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