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Items: 7

1.

Inhibition of arginase by CB-1158 blocks myeloid cell-mediated immune suppression in the tumor microenvironment.

Steggerda SM, Bennett MK, Chen J, Emberley E, Huang T, Janes JR, Li W, MacKinnon AL, Makkouk A, Marguier G, Murray PJ, Neou S, Pan A, Parlati F, Rodriguez MLM, Van de Velde LA, Wang T, Works M, Zhang J, Zhang W, Gross MI.

J Immunother Cancer. 2017 Dec 19;5(1):101. doi: 10.1186/s40425-017-0308-4.

2.

Antitumor activity of the glutaminase inhibitor CB-839 in triple-negative breast cancer.

Gross MI, Demo SD, Dennison JB, Chen L, Chernov-Rogan T, Goyal B, Janes JR, Laidig GJ, Lewis ER, Li J, Mackinnon AL, Parlati F, Rodriguez ML, Shwonek PJ, Sjogren EB, Stanton TF, Wang T, Yang J, Zhao F, Bennett MK.

Mol Cancer Ther. 2014 Apr;13(4):890-901. doi: 10.1158/1535-7163.MCT-13-0870. Epub 2014 Feb 12.

3.

Cross-species comparisons of the pharmacokinetics of ibudilast.

Sanftner LM, Gibbons JA, Gross MI, Suzuki BM, Gaeta FC, Johnson KW.

Xenobiotica. 2009 Dec;39(12):964-77. doi: 10.3109/00498250903254340.

PMID:
19925385
4.

Ibudilast in healthy volunteers: safety, tolerability and pharmacokinetics with single and multiple doses.

Rolan P, Gibbons JA, He L, Chang E, Jones D, Gross MI, Davidson JB, Sanftner LM, Johnson KW.

Br J Clin Pharmacol. 2008 Dec;66(6):792-801. doi: 10.1111/j.1365-2125.2008.03270.x.

5.

The glial modulatory drug AV411 attenuates mechanical allodynia in rat models of neuropathic pain.

Ledeboer A, Liu T, Shumilla JA, Mahoney JH, Vijay S, Gross MI, Vargas JA, Sultzbaugh L, Claypool MD, Sanftner LM, Watkins LR, Johnson KW.

Neuron Glia Biol. 2006 Nov;2(4):279-91. doi: 10.1017/S1740925X0700035X.

6.

DNA binding ligands with improved in vitro and in vivo potency against drug-resistant Staphylococcus aureus.

Hu W, Bürli RW, Kaizerman JA, Johnson KW, Gross MI, Iwamoto M, Jones P, Lofland D, Difuntorum S, Chen H, Bozdogan B, Appelbaum PC, Moser HE.

J Med Chem. 2004 Aug 26;47(18):4352-5.

PMID:
15317448
7.

DNA binding ligands targeting drug-resistant bacteria: structure, activity, and pharmacology.

Kaizerman JA, Gross MI, Ge Y, White S, Hu W, Duan JX, Baird EE, Johnson KW, Tanaka RD, Moser HE, Bürli RW.

J Med Chem. 2003 Aug 28;46(18):3914-29.

PMID:
12930152

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