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Items: 1 to 50 of 129

1.

Structural Basis for a Species-Specific Determinant of an SIV Vif Protein toward Hominid APOBEC3G Antagonism.

Binning JM, Chesarino NM, Emerman M, Gross JD.

Cell Host Microbe. 2019 Dec 11;26(6):739-747.e4. doi: 10.1016/j.chom.2019.10.014.

PMID:
31830442
2.

Pat1 activates late steps in mRNA decay by multiple mechanisms.

Lobel JH, Tibble RW, Gross JD.

Proc Natl Acad Sci U S A. 2019 Nov 19;116(47):23512-23517. doi: 10.1073/pnas.1905455116. Epub 2019 Nov 5.

PMID:
31690658
3.

HP1 reshapes nucleosome core to promote phase separation of heterochromatin.

Sanulli S, Trnka MJ, Dharmarajan V, Tibble RW, Pascal BD, Burlingame AL, Griffin PR, Gross JD, Narlikar GJ.

Nature. 2019 Nov;575(7782):390-394. doi: 10.1038/s41586-019-1669-2. Epub 2019 Oct 16.

PMID:
31618757
4.

Preclinical Testing of Nalfurafine as an Opioid-sparing Adjuvant that Potentiates Analgesia by the Mu Opioid Receptor-targeting Agonist Morphine.

Kaski SW, White AN, Gross JD, Trexler KR, Wix K, Harland AA, Prisinzano TE, Aubé J, Kinsey SG, Kenakin T, Siderovski DP, Setola V.

J Pharmacol Exp Ther. 2019 Nov;371(2):487-499. doi: 10.1124/jpet.118.255661. Epub 2019 Sep 6.

PMID:
31492823
5.

ARIH2 Is a Vif-Dependent Regulator of CUL5-Mediated APOBEC3G Degradation in HIV Infection.

Hüttenhain R, Xu J, Burton LA, Gordon DE, Hultquist JF, Johnson JR, Satkamp L, Hiatt J, Rhee DY, Baek K, Crosby DC, Frankel AD, Marson A, Harper JW, Alpi AF, Schulman BA, Gross JD, Krogan NJ.

Cell Host Microbe. 2019 Jul 10;26(1):86-99.e7. doi: 10.1016/j.chom.2019.05.008. Epub 2019 Jun 25.

PMID:
31253590
6.

Role of RGS12 in the differential regulation of kappa opioid receptor-dependent signaling and behavior.

Gross JD, Kaski SW, Schmidt KT, Cogan ES, Boyt KM, Wix K, Schroer AB, McElligott ZA, Siderovski DP, Setola V.

Neuropsychopharmacology. 2019 Sep;44(10):1728-1741. doi: 10.1038/s41386-019-0423-7. Epub 2019 May 29.

PMID:
31141817
7.

Conformational Dynamics of the HIV-Vif Protein Complex.

Ball KA, Chan LM, Stanley DJ, Tierney E, Thapa S, Ta HM, Burton L, Binning JM, Jacobson MP, Gross JD.

Biophys J. 2019 Apr 23;116(8):1432-1445. doi: 10.1016/j.bpj.2019.03.014. Epub 2019 Mar 23.

PMID:
30961890
8.

Publisher Correction: Structural and molecular mechanisms for the control of eukaryotic 5'-3' mRNA decay.

Mugridge JS, Coller J, Gross JD.

Nat Struct Mol Biol. 2019 Feb;26(2):147-148. doi: 10.1038/s41594-018-0178-6.

PMID:
30575809
9.

Structural and molecular mechanisms for the control of eukaryotic 5'-3' mRNA decay.

Mugridge JS, Coller J, Gross JD.

Nat Struct Mol Biol. 2018 Dec;25(12):1077-1085. doi: 10.1038/s41594-018-0164-z. Epub 2018 Dec 5. Review. Erratum in: Nat Struct Mol Biol. 2019 Feb;26(2):147-148.

PMID:
30518847
10.

Decapping enzymes STOP "cancer" ribosomes in their tracks.

Mugridge JS, Gross JD.

EMBO J. 2018 Dec 3;37(23). pii: e100801. doi: 10.15252/embj.2018100801. Epub 2018 Nov 19. No abstract available.

11.

A Viral Protein Restricts Drosophila RNAi Immunity by Regulating Argonaute Activity and Stability.

Nayak A, Kim DY, Trnka MJ, Kerr CH, Lidsky PV, Stanley DJ, Rivera BM, Li KH, Burlingame AL, Jan E, Frydman J, Gross JD, Andino R.

Cell Host Microbe. 2018 Oct 10;24(4):542-557.e9. doi: 10.1016/j.chom.2018.09.006.

12.

CRL4AMBRA1 targets Elongin C for ubiquitination and degradation to modulate CRL5 signaling.

Chen SH, Jang GM, Hüttenhain R, Gordon DE, Du D, Newton BW, Johnson JR, Hiatt J, Hultquist JF, Johnson TL, Liu YL, Burton LA, Ye J, Reichermeier KM, Stroud RM, Marson A, Debnath J, Gross JD, Krogan NJ.

EMBO J. 2018 Sep 14;37(18). pii: e97508. doi: 10.15252/embj.201797508. Epub 2018 Aug 30.

13.

Novel behavioral assays of spontaneous and precipitated THC withdrawal in mice.

Trexler KR, Nass SR, Crowe MS, Gross JD, Jones MS, McKitrick AW, Siderovski DP, Kinsey SG.

Drug Alcohol Depend. 2018 Oct 1;191:14-24. doi: 10.1016/j.drugalcdep.2018.05.029. Epub 2018 Jul 7.

14.

Development of Full Sweet, Umami, and Bitter Taste Responsiveness Requires Regulator of G protein Signaling-21 (RGS21).

Schroer AB, Gross JD, Kaski SW, Wix K, Siderovski DP, Vandenbeuch A, Setola V.

Chem Senses. 2018 May 23;43(5):367-378. doi: 10.1093/chemse/bjy024.

15.

Control of mRNA decapping by autoinhibition.

Paquette DR, Tibble RW, Daifuku TS, Gross JD.

Nucleic Acids Res. 2018 Jul 6;46(12):6318-6329. doi: 10.1093/nar/gky233.

16.

Structure of the activated Edc1-Dcp1-Dcp2-Edc3 mRNA decapping complex with substrate analog poised for catalysis.

Mugridge JS, Tibble RW, Ziemniak M, Jemielity J, Gross JD.

Nat Commun. 2018 Mar 20;9(1):1152. doi: 10.1038/s41467-018-03536-x.

17.

Regulator of G protein signaling-12 modulates the dopamine transporter in ventral striatum and locomotor responses to psychostimulants.

Gross JD, Kaski SW, Schroer AB, Wix KA, Siderovski DP, Setola V.

J Psychopharmacol. 2018 Feb;32(2):191-203. doi: 10.1177/0269881117742100. Epub 2018 Jan 24.

18.

Fab-based inhibitors reveal ubiquitin independent functions for HIV Vif neutralization of APOBEC3 restriction factors.

Binning JM, Smith AM, Hultquist JF, Craik CS, Caretta Cartozo N, Campbell MG, Burton L, La Greca F, McGregor MJ, Ta HM, Bartholomeeusen K, Peterlin BM, Krogan NJ, Sevillano N, Cheng Y, Gross JD.

PLoS Pathog. 2018 Jan 5;14(1):e1006830. doi: 10.1371/journal.ppat.1006830. eCollection 2018 Jan.

19.

Application of a Schizosaccharomyces pombe Edc1-fused Dcp1-Dcp2 decapping enzyme for transcription start site mapping.

Paquette DR, Mugridge JS, Weinberg DE, Gross JD.

RNA. 2018 Feb;24(2):251-257. doi: 10.1261/rna.062737.117. Epub 2017 Nov 3.

20.

Making Sense of Multifunctional Proteins: Human Immunodeficiency Virus Type 1 Accessory and Regulatory Proteins and Connections to Transcription.

Faust TB, Binning JM, Gross JD, Frankel AD.

Annu Rev Virol. 2017 Sep 29;4(1):241-260. doi: 10.1146/annurev-virology-101416-041654. Review.

21.

Biochemical Basis for Distinct Roles of the Heterochromatin Proteins Swi6 and Chp2.

Isaac RS, Sanulli S, Tibble R, Hornsby M, Ravalin M, Craik CS, Gross JD, Narlikar GJ.

J Mol Biol. 2017 Nov 24;429(23):3666-3677. doi: 10.1016/j.jmb.2017.09.012. Epub 2017 Sep 20.

22.

CBFß and HIV Infection.

Kim DY, Gross JD.

Adv Exp Med Biol. 2017;962:415-431. doi: 10.1007/978-981-10-3233-2_25. Review.

PMID:
28299671
23.

Distortion of histone octamer core promotes nucleosome mobilization by a chromatin remodeler.

Sinha KK, Gross JD, Narlikar GJ.

Science. 2017 Jan 20;355(6322). pii: eaaa3761. doi: 10.1126/science.aaa3761.

24.

Molecular biology: Messenger RNAs marked for longer life.

Weinberg DE, Gross JD.

Nature. 2017 Jan 19;541(7637):293-294. doi: 10.1038/nature21109. Epub 2016 Dec 21. No abstract available.

PMID:
28002405
25.

Structural basis of mRNA-cap recognition by Dcp1-Dcp2.

Mugridge JS, Ziemniak M, Jemielity J, Gross JD.

Nat Struct Mol Biol. 2016 Nov;23(11):987-994. doi: 10.1038/nsmb.3301. Epub 2016 Oct 3.

26.

Reduction of GPSM3 expression akin to the arthritis-protective SNP rs204989 differentially affects migration in a neutrophil model.

Gall BJ, Schroer AB, Gross JD, Setola V, Siderovski DP.

Genes Immun. 2016 Sep;17(6):321-7. doi: 10.1038/gene.2016.26. Epub 2016 Jun 16.

27.

Two-headed tetraphosphate cap analogs are inhibitors of the Dcp1/2 RNA decapping complex.

Ziemniak M, Mugridge JS, Kowalska J, Rhoads RE, Gross JD, Jemielity J.

RNA. 2016 Apr;22(4):518-29. doi: 10.1261/rna.055152.115. Epub 2016 Jan 29.

28.

Genetic variations in GPSM3 associated with protection from rheumatoid arthritis affect its transcript abundance.

Gall BJ, Wilson A, Schroer AB, Gross JD, Stoilov P, Setola V, Watkins CM, Siderovski DP.

Genes Immun. 2016 Mar;17(2):139-47. doi: 10.1038/gene.2016.3. Epub 2016 Jan 28.

29.

Thermodynamics of Rev-RNA interactions in HIV-1 Rev-RRE assembly.

Jayaraman B, Mavor D, Gross JD, Frankel AD.

Biochemistry. 2015 Oct 27;54(42):6545-54. doi: 10.1021/acs.biochem.5b00876. Epub 2015 Oct 13.

30.

Lineage-Specific Viral Hijacking of Non-canonical E3 Ubiquitin Ligase Cofactors in the Evolution of Vif Anti-APOBEC3 Activity.

Kane JR, Stanley DJ, Hultquist JF, Johnson JR, Mietrach N, Binning JM, Jónsson SR, Barelier S, Newton BW, Johnson TL, Franks-Skiba KE, Li M, Brown WL, Gunnarsson HI, Adalbjornsdóttir A, Fraser JS, Harris RS, Andrésdóttir V, Gross JD, Krogan NJ.

Cell Rep. 2015 May 26;11(8):1236-50. doi: 10.1016/j.celrep.2015.04.038. Epub 2015 May 14.

31.

A mutually assured destruction mechanism attenuates light signaling in Arabidopsis.

Ni W, Xu SL, Tepperman JM, Stanley DJ, Maltby DA, Gross JD, Burlingame AL, Wang ZY, Quail PH.

Science. 2014 Jun 6;344(6188):1160-1164. doi: 10.1126/science.1250778.

32.

Active site conformational dynamics are coupled to catalysis in the mRNA decapping enzyme Dcp2.

Aglietti RA, Floor SN, McClendon CL, Jacobson MP, Gross JD.

Structure. 2013 Sep 3;21(9):1571-80. doi: 10.1016/j.str.2013.06.021. Epub 2013 Aug 1.

33.

The glucocorticoid receptor dimer interface allosterically transmits sequence-specific DNA signals.

Watson LC, Kuchenbecker KM, Schiller BJ, Gross JD, Pufall MA, Yamamoto KR.

Nat Struct Mol Biol. 2013 Jul;20(7):876-83. doi: 10.1038/nsmb.2595. Epub 2013 Jun 2.

34.

Judge, jury, and executioner: DXO functions as a decapping enzyme and exoribonuclease in pre-mRNA quality control.

Mugridge JS, Gross JD.

Mol Cell. 2013 Apr 11;50(1):2-4. doi: 10.1016/j.molcel.2013.03.025.

35.

From systems to structure: bridging networks and mechanism.

Fraser JS, Gross JD, Krogan NJ.

Mol Cell. 2013 Jan 24;49(2):222-31. doi: 10.1016/j.molcel.2013.01.003. Review.

36.

CBFβ stabilizes HIV Vif to counteract APOBEC3 at the expense of RUNX1 target gene expression.

Kim DY, Kwon E, Hartley PD, Crosby DC, Mann S, Krogan NJ, Gross JD.

Mol Cell. 2013 Feb 21;49(4):632-44. doi: 10.1016/j.molcel.2012.12.012. Epub 2013 Jan 17.

37.

Inhibition of a NEDD8 Cascade Restores Restriction of HIV by APOBEC3G.

Stanley DJ, Bartholomeeusen K, Crosby DC, Kim DY, Kwon E, Yen L, Cartozo NC, Li M, Jäger S, Mason-Herr J, Hayashi F, Yokoyama S, Krogan NJ, Harris RS, Peterlin BM, Gross JD.

PLoS Pathog. 2012 Dec;8(12):e1003085. doi: 10.1371/journal.ppat.1003085. Epub 2012 Dec 27.

38.

The crystal structure of the periplasmic domain of Vibrio parahaemolyticus CpxA.

Kwon E, Kim DY, Ngo TD, Gross CA, Gross JD, Kim KK.

Protein Sci. 2012 Sep;21(9):1334-43. doi: 10.1002/pro.2120.

39.

Interdomain dynamics and coactivation of the mRNA decapping enzyme Dcp2 are mediated by a gatekeeper tryptophan.

Floor SN, Borja MS, Gross JD.

Proc Natl Acad Sci U S A. 2012 Feb 21;109(8):2872-7. doi: 10.1073/pnas.1113620109. Epub 2012 Feb 9.

40.

Vif hijacks CBF-β to degrade APOBEC3G and promote HIV-1 infection.

Jäger S, Kim DY, Hultquist JF, Shindo K, LaRue RS, Kwon E, Li M, Anderson BD, Yen L, Stanley D, Mahon C, Kane J, Franks-Skiba K, Cimermancic P, Burlingame A, Sali A, Craik CS, Harris RS, Gross JD, Krogan NJ.

Nature. 2011 Dec 21;481(7381):371-5. doi: 10.1038/nature10693.

41.

Dcp1 links coactivators of mRNA decapping to Dcp2 by proline recognition.

Borja MS, Piotukh K, Freund C, Gross JD.

RNA. 2011 Feb;17(2):278-90. doi: 10.1261/rna.2382011. Epub 2010 Dec 10.

42.

Limited beneficial effects of perfluorocarbon emulsions on encapsulated cells in culture: experimental and modeling studies.

Goh F, Gross JD, Simpson NE, Sambanis A.

J Biotechnol. 2010 Oct 15;150(2):232-9. doi: 10.1016/j.jbiotec.2010.08.013. Epub 2010 Sep 8.

43.

The crystal structure Escherichia coli Spy.

Kwon E, Kim DY, Gross CA, Gross JD, Kim KK.

Protein Sci. 2010 Nov;19(11):2252-9. doi: 10.1002/pro.489.

44.

A split active site couples cap recognition by Dcp2 to activation.

Floor SN, Jones BN, Hernandez GA, Gross JD.

Nat Struct Mol Biol. 2010 Sep;17(9):1096-101. doi: 10.1038/nsmb.1879. Epub 2010 Aug 15.

45.

Identification and analysis of the interaction between Edc3 and Dcp2 in Saccharomyces cerevisiae.

Harigaya Y, Jones BN, Muhlrad D, Gross JD, Parker R.

Mol Cell Biol. 2010 Mar;30(6):1446-56. doi: 10.1128/MCB.01305-09. Epub 2010 Jan 19.

46.

An extended structure of the APOBEC3G catalytic domain suggests a unique holoenzyme model.

Harjes E, Gross PJ, Chen KM, Lu Y, Shindo K, Nowarski R, Gross JD, Kotler M, Harris RS, Matsuo H.

J Mol Biol. 2009 Jun 26;389(5):819-32. doi: 10.1016/j.jmb.2009.04.031. Epub 2009 Apr 21.

47.

Acidic Ca2+ stores, excitability, and cell patterning in Dictyostelium discoideum.

Gross JD.

Eukaryot Cell. 2009 May;8(5):696-702. doi: 10.1128/EC.00360-08. Epub 2009 Feb 27. Review. No abstract available.

48.

SRP RNA controls a conformational switch regulating the SRP-SRP receptor interaction.

Neher SB, Bradshaw N, Floor SN, Gross JD, Walter P.

Nat Struct Mol Biol. 2008 Sep;15(9):916-23.

49.

A kinetic assay to monitor RNA decapping under single- turnover conditions.

Jones BN, Quang-Dang DU, Oku Y, Gross JD.

Methods Enzymol. 2008;448:23-40. doi: 10.1016/S0076-6879(08)02602-5.

PMID:
19111169
50.

Ligand-induced conformational heterogeneity of cytochrome P450 CYP119 identified by 2D NMR spectroscopy with the unnatural amino acid (13)C-p-methoxyphenylalanine.

Lampe JN, Floor SN, Gross JD, Nishida CR, Jiang Y, Trnka MJ, Ortiz de Montellano PR.

J Am Chem Soc. 2008 Dec 3;130(48):16168-9. doi: 10.1021/ja8071463.

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