Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 171


Discovery of the extracytoplasmic function σ factors.

Lonetto MA, Donohue TJ, Gross CA, Buttner MJ.

Mol Microbiol. 2019 Aug;112(2):348-355. doi: 10.1111/mmi.14307. Epub 2019 Jun 17. Review.


Topoisomerase IV can functionally replace all type 1A topoisomerases in Bacillus subtilis.

Reuß DR, Faßhauer P, Mroch PJ, Ul-Haq I, Koo BM, Pöhlein A, Gross CA, Daniel R, Brantl S, Stülke J.

Nucleic Acids Res. 2019 Jun 4;47(10):5231-5242. doi: 10.1093/nar/gkz260.


Enabling genetic analysis of diverse bacteria with Mobile-CRISPRi.

Peters JM, Koo BM, Patino R, Heussler GE, Hearne CC, Qu J, Inclan YF, Hawkins JS, Lu CHS, Silvis MR, Harden MM, Osadnik H, Peters JE, Engel JN, Dutton RJ, Grossman AD, Gross CA, Rosenberg OS.

Nat Microbiol. 2019 Feb;4(2):244-250. doi: 10.1038/s41564-018-0327-z. Epub 2019 Jan 7.


Structure and Function of the Transmembrane Domain of NsaS, an Antibiotic Sensing Histidine Kinase in Staphylococcus aureus.

Bhate MP, Lemmin T, Kuenze G, Mensa B, Ganguly S, Peters JM, Schmidt N, Pelton JG, Gross CA, Meiler J, DeGrado WF.

J Am Chem Soc. 2018 Jun 20;140(24):7471-7485. doi: 10.1021/jacs.7b09670. Epub 2018 Jun 9.


A Stress Response that Monitors and Regulates mRNA Structure Is Central to Cold Shock Adaptation.

Zhang Y, Burkhardt DH, Rouskin S, Li GW, Weissman JS, Gross CA.

Mol Cell. 2018 Apr 19;70(2):274-286.e7. doi: 10.1016/j.molcel.2018.02.035. Epub 2018 Apr 5.


Marine Mammal Microbiota Yields Novel Antibiotic with Potent Activity Against Clostridium difficile.

Ochoa JL, Sanchez LM, Koo BM, Doherty JS, Rajendram M, Huang KC, Gross CA, Linington RG.

ACS Infect Dis. 2018 Jan 12;4(1):59-67. doi: 10.1021/acsinfecdis.7b00105. Epub 2017 Oct 18.


Ribosomal Architecture: Constraints Imposed by the Need for Self-Production.

Hussmann JA, Osadnik H, Gross CA.

Curr Biol. 2017 Aug 21;27(16):R798-R800. doi: 10.1016/j.cub.2017.06.080.


Correction: A Chemical-Genomic Screen of Neglected Antibiotics Reveals Illicit Transport of Kasugamycin and Blasticidin S.

Shiver AL, Osadnik H, Kritikos G, Li B, Krogan N, Typas A, Gross CA.

PLoS Genet. 2017 Jul 21;13(7):e1006902. doi: 10.1371/journal.pgen.1006902. eCollection 2017 Jul.


Global analysis of translation termination in E. coli.

Baggett NE, Zhang Y, Gross CA.

PLoS Genet. 2017 Mar 16;13(3):e1006676. doi: 10.1371/journal.pgen.1006676. eCollection 2017 Mar.


Construction and Analysis of Two Genome-Scale Deletion Libraries for Bacillus subtilis.

Koo BM, Kritikos G, Farelli JD, Todor H, Tong K, Kimsey H, Wapinski I, Galardini M, Cabal A, Peters JM, Hachmann AB, Rudner DZ, Allen KN, Typas A, Gross CA.

Cell Syst. 2017 Mar 22;4(3):291-305.e7. doi: 10.1016/j.cels.2016.12.013. Epub 2017 Feb 8.


Operon mRNAs are organized into ORF-centric structures that predict translation efficiency.

Burkhardt DH, Rouskin S, Zhang Y, Li GW, Weissman JS, Gross CA.

Elife. 2017 Jan 31;6. pii: e22037. doi: 10.7554/eLife.22037.


A Multiplexed Single-Cell CRISPR Screening Platform Enables Systematic Dissection of the Unfolded Protein Response.

Adamson B, Norman TM, Jost M, Cho MY, Nuñez JK, Chen Y, Villalta JE, Gilbert LA, Horlbeck MA, Hein MY, Pak RA, Gray AN, Gross CA, Dixit A, Parnas O, Regev A, Weissman JS.

Cell. 2016 Dec 15;167(7):1867-1882.e21. doi: 10.1016/j.cell.2016.11.048.


Identification of Two Phosphate Starvation-induced Wall Teichoic Acid Hydrolases Provides First Insights into the Degradative Pathway of a Key Bacterial Cell Wall Component.

Myers CL, Li FK, Koo BM, El-Halfawy OM, French S, Gross CA, Strynadka NC, Brown ED.

J Biol Chem. 2016 Dec 9;291(50):26066-26082. Epub 2016 Oct 25.


Depletion of Undecaprenyl Pyrophosphate Phosphatases Disrupts Cell Envelope Biogenesis in Bacillus subtilis.

Zhao H, Sun Y, Peters JM, Gross CA, Garner EC, Helmann JD.

J Bacteriol. 2016 Oct 7;198(21):2925-2935. Print 2016 Nov 1.


A Chemical-Genomic Screen of Neglected Antibiotics Reveals Illicit Transport of Kasugamycin and Blasticidin S.

Shiver AL, Osadnik H, Kritikos G, Li B, Krogan N, Typas A, Gross CA.

PLoS Genet. 2016 Jun 29;12(6):e1006124. doi: 10.1371/journal.pgen.1006124. eCollection 2016 Jun. Erratum in: PLoS Genet. 2017 Jul 21;13(7):e1006902.


A Comprehensive, CRISPR-based Functional Analysis of Essential Genes in Bacteria.

Peters JM, Colavin A, Shi H, Czarny TL, Larson MH, Wong S, Hawkins JS, Lu CHS, Koo BM, Marta E, Shiver AL, Whitehead EH, Weissman JS, Brown ED, Qi LS, Huang KC, Gross CA.

Cell. 2016 Jun 2;165(6):1493-1506. doi: 10.1016/j.cell.2016.05.003. Epub 2016 May 26.


DksA regulates RNA polymerase in Escherichia coli through a network of interactions in the secondary channel that includes Sequence Insertion 1.

Parshin A, Shiver AL, Lee J, Ozerova M, Schneidman-Duhovny D, Gross CA, Borukhov S.

Proc Natl Acad Sci U S A. 2015 Dec 15;112(50):E6862-71. doi: 10.1073/pnas.1521365112. Epub 2015 Nov 24. Erratum in: Proc Natl Acad Sci U S A. 2016 Jan 5;113(1):E103.


Bacterial CRISPR: accomplishments and prospects.

Peters JM, Silvis MR, Zhao D, Hawkins JS, Gross CA, Qi LS.

Curr Opin Microbiol. 2015 Oct;27:121-6. doi: 10.1016/j.mib.2015.08.007. Epub 2015 Sep 10. Review.


High-throughput bacterial functional genomics in the sequencing era.

Gray AN, Koo BM, Shiver AL, Peters JM, Osadnik H, Gross CA.

Curr Opin Microbiol. 2015 Oct;27:86-95. doi: 10.1016/j.mib.2015.07.012. Epub 2015 Sep 1. Review.


Coordination of peptidoglycan synthesis and outer membrane constriction during Escherichia coli cell division.

Gray AN, Egan AJ, Van't Veer IL, Verheul J, Colavin A, Koumoutsi A, Biboy J, Altelaar AF, Damen MJ, Huang KC, Simorre JP, Breukink E, den Blaauwen T, Typas A, Gross CA, Vollmer W.

Elife. 2015 May 7;4. doi: 10.7554/eLife.07118.


MurJ and a novel lipid II flippase are required for cell wall biogenesis in Bacillus subtilis.

Meeske AJ, Sham LT, Kimsey H, Koo BM, Gross CA, Bernhardt TG, Rudner DZ.

Proc Natl Acad Sci U S A. 2015 May 19;112(20):6437-42. doi: 10.1073/pnas.1504967112. Epub 2015 Apr 27.


Editorial overview: Cell regulation: when you think you know it all, there is another layer to be discovered.

Gross CA, Gründling A.

Curr Opin Microbiol. 2015 Apr;24:v-vii. doi: 10.1016/j.mib.2015.02.001. Epub 2015 Feb 20. No abstract available.


MicL, a new σE-dependent sRNA, combats envelope stress by repressing synthesis of Lpp, the major outer membrane lipoprotein.

Guo MS, Updegrove TB, Gogol EB, Shabalina SA, Gross CA, Storz G.

Genes Dev. 2014 Jul 15;28(14):1620-34. doi: 10.1101/gad.243485.114.


Bacterial sigma factors: a historical, structural, and genomic perspective.

Feklístov A, Sharon BD, Darst SA, Gross CA.

Annu Rev Microbiol. 2014;68:357-76. doi: 10.1146/annurev-micro-092412-155737. Epub 2014 Jun 18. Review.


Stress-induced remodeling of the bacterial proteome.

Guo MS, Gross CA.

Curr Biol. 2014 May 19;24(10):R424-34. doi: 10.1016/j.cub.2014.03.023. Review.


A pause sequence enriched at translation start sites drives transcription dynamics in vivo.

Larson MH, Mooney RA, Peters JM, Windgassen T, Nayak D, Gross CA, Block SM, Greenleaf WJ, Landick R, Weissman JS.

Science. 2014 May 30;344(6187):1042-7. doi: 10.1126/science.1251871. Epub 2014 May 1.


Promoter melting by an alternative σ, one base at a time.

Darst SA, Feklistov A, Gross CA.

Nat Struct Mol Biol. 2014 Apr;21(4):350-1. doi: 10.1038/nsmb.2798. No abstract available.


Heat shock transcription factor σ32 co-opts the signal recognition particle to regulate protein homeostasis in E. coli.

Lim B, Miyazaki R, Neher S, Siegele DA, Ito K, Walter P, Akiyama Y, Yura T, Gross CA.

PLoS Biol. 2013 Dec;11(12):e1001735. doi: 10.1371/journal.pbio.1001735. Epub 2013 Dec 17.


Design of orthogonal genetic switches based on a crosstalk map of σs, anti-σs, and promoters.

Rhodius VA, Segall-Shapiro TH, Sharon BD, Ghodasara A, Orlova E, Tabakh H, Burkhardt DH, Clancy K, Peterson TC, Gross CA, Voigt CA.

Mol Syst Biol. 2013 Oct 29;9:702. doi: 10.1038/msb.2013.58.


Dual molecular signals mediate the bacterial response to outer-membrane stress.

Lima S, Guo MS, Chaba R, Gross CA, Sauer RT.

Science. 2013 May 17;340(6134):837-41. doi: 10.1126/science.1235358.


Randomized selection design trial evaluating CD8+-enriched versus unselected tumor-infiltrating lymphocytes for adoptive cell therapy for patients with melanoma.

Dudley ME, Gross CA, Somerville RP, Hong Y, Schaub NP, Rosati SF, White DE, Nathan D, Restifo NP, Steinberg SM, Wunderlich JR, Kammula US, Sherry RM, Yang JC, Phan GQ, Hughes MS, Laurencot CM, Rosenberg SA.

J Clin Oncol. 2013 Jun 10;31(17):2152-9. doi: 10.1200/JCO.2012.46.6441. Epub 2013 May 6.


Covalent intermediate in the catalytic mechanism of the radical S-adenosyl-L-methionine methyl synthase RlmN trapped by mutagenesis.

McCusker KP, Medzihradszky KF, Shiver AL, Nichols RJ, Yan F, Maltby DA, Gross CA, Fujimori DG.

J Am Chem Soc. 2012 Oct 31;134(43):18074-81. doi: 10.1021/ja307855d. Epub 2012 Oct 22.


The crystal structure of the periplasmic domain of Vibrio parahaemolyticus CpxA.

Kwon E, Kim DY, Ngo TD, Gross CA, Gross JD, Kim KK.

Protein Sci. 2012 Sep;21(9):1334-43. doi: 10.1002/pro.2120.


Tumor-specific CD4+ melanoma tumor-infiltrating lymphocytes.

Friedman KM, Prieto PA, Devillier LE, Gross CA, Yang JC, Wunderlich JR, Rosenberg SA, Dudley ME.

J Immunother. 2012 Jun;35(5):400-8. doi: 10.1097/CJI.0b013e31825898c5.


From the regulation of peptidoglycan synthesis to bacterial growth and morphology.

Typas A, Banzhaf M, Gross CA, Vollmer W.

Nat Rev Microbiol. 2011 Dec 28;10(2):123-36. doi: 10.1038/nrmicro2677. Review.


Predicting the strength of UP-elements and full-length E. coli σE promoters.

Rhodius VA, Mutalik VK, Gross CA.

Nucleic Acids Res. 2012 Apr;40(7):2907-24. doi: 10.1093/nar/gkr1190. Epub 2011 Dec 8.


Selective ribosome profiling reveals the cotranslational chaperone action of trigger factor in vivo.

Oh E, Becker AH, Sandikci A, Huber D, Chaba R, Gloge F, Nichols RJ, Typas A, Gross CA, Kramer G, Weissman JS, Bukau B.

Cell. 2011 Dec 9;147(6):1295-308. doi: 10.1016/j.cell.2011.10.044.


Unexpected stress-reducing effect of PhaP, a poly(3-hydroxybutyrate) granule-associated protein, in Escherichia coli.

de Almeida A, Catone MV, Rhodius VA, Gross CA, Pettinari MJ.

Appl Environ Microbiol. 2011 Sep;77(18):6622-9. doi: 10.1128/AEM.05469-11. Epub 2011 Jul 22.


Small RNAs endow a transcriptional activator with essential repressor functions for single-tier control of a global stress regulon.

Gogol EB, Rhodius VA, Papenfort K, Vogel J, Gross CA.

Proc Natl Acad Sci U S A. 2011 Aug 2;108(31):12875-80. doi: 10.1073/pnas.1109379108. Epub 2011 Jul 18.


Using DNA microarrays to assay part function.

Rhodius VA, Gross CA.

Methods Enzymol. 2011;497:75-113. doi: 10.1016/B978-0-12-385075-1.00004-4.


Signal integration by DegS and RseB governs the σ E-mediated envelope stress response in Escherichia coli.

Chaba R, Alba BM, Guo MS, Sohn J, Ahuja N, Sauer RT, Gross CA.

Proc Natl Acad Sci U S A. 2011 Feb 1;108(5):2106-11. doi: 10.1073/pnas.1019277108. Epub 2011 Jan 18.


Phenotypic landscape of a bacterial cell.

Nichols RJ, Sen S, Choo YJ, Beltrao P, Zietek M, Chaba R, Lee S, Kazmierczak KM, Lee KJ, Wong A, Shales M, Lovett S, Winkler ME, Krogan NJ, Typas A, Gross CA.

Cell. 2011 Jan 7;144(1):143-56. doi: 10.1016/j.cell.2010.11.052. Epub 2010 Dec 23.


Regulation of peptidoglycan synthesis by outer-membrane proteins.

Typas A, Banzhaf M, van den Berg van Saparoea B, Verheul J, Biboy J, Nichols RJ, Zietek M, Beilharz K, Kannenberg K, von Rechenberg M, Breukink E, den Blaauwen T, Gross CA, Vollmer W.

Cell. 2010 Dec 23;143(7):1097-109. doi: 10.1016/j.cell.2010.11.038.


The crystal structure Escherichia coli Spy.

Kwon E, Kim DY, Gross CA, Gross JD, Kim KK.

Protein Sci. 2010 Nov;19(11):2252-9. doi: 10.1002/pro.489.


CD8+ enriched "young" tumor infiltrating lymphocytes can mediate regression of metastatic melanoma.

Dudley ME, Gross CA, Langhan MM, Garcia MR, Sherry RM, Yang JC, Phan GQ, Kammula US, Hughes MS, Citrin DE, Restifo NP, Wunderlich JR, Prieto PA, Hong JJ, Langan RC, Zlott DA, Morton KE, White DE, Laurencot CM, Rosenberg SA.

Clin Cancer Res. 2010 Dec 15;16(24):6122-31. doi: 10.1158/1078-0432.CCR-10-1297. Epub 2010 Jul 28.


beta2-agonists promote host defense against bacterial infection in primary human bronchial epithelial cells.

Gross CA, Bowler RP, Green RM, Weinberger AR, Schnell C, Chu HW.

BMC Pulm Med. 2010 May 14;10:30. doi: 10.1186/1471-2466-10-30.


CMEIAS color segmentation: an improved computing technology to process color images for quantitative microbial ecology studies at single-cell resolution.

Gross CA, Reddy CK, Dazzo FB.

Microb Ecol. 2010 Feb;59(2):400-14. doi: 10.1007/s00248-009-9616-7. Epub 2009 Dec 19.


Reduced capacity of alternative sigmas to melt promoters ensures stringent promoter recognition.

Koo BM, Rhodius VA, Nonaka G, deHaseth PL, Gross CA.

Genes Dev. 2009 Oct 15;23(20):2426-36. doi: 10.1101/gad.1843709.


Promoter strength properties of the complete sigma E regulon of Escherichia coli and Salmonella enterica.

Mutalik VK, Nonaka G, Ades SE, Rhodius VA, Gross CA.

J Bacteriol. 2009 Dec;191(23):7279-87. doi: 10.1128/JB.01047-09. Epub 2009 Sep 25.


Dissection of recognition determinants of Escherichia coli sigma32 suggests a composite -10 region with an 'extended -10' motif and a core -10 element.

Koo BM, Rhodius VA, Campbell EA, Gross CA.

Mol Microbiol. 2009 May;72(4):815-29. doi: 10.1111/j.1365-2958.2009.06690.x. Epub 2009 Apr 14.

Supplemental Content

Loading ...
Support Center