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Items: 29

1.

CD20-directed small modular immunopharmaceutical, TRU-015, depletes normal and malignant B cells.

Hayden-Ledbetter MS, Cerveny CG, Espling E, Brady WA, Grosmaire LS, Tan P, Bader R, Slater S, Nilsson CA, Barone DS, Simon A, Bradley C, Thompson PA, Wahl AF, Ledbetter JA.

Clin Cancer Res. 2009 Apr 15;15(8):2739-46. doi: 10.1158/1078-0432.CCR-08-1694. Epub 2009 Apr 7.

2.

Overview of the Third International Workshop on Swine Leukocyte Differentiation Antigens.

Haverson K, Saalmüller A, Alvarez B, Alonso F, Bailey M, Bianchi AT, Boersma WJ, Chen Z, Davis WC, Dominguez J, Engelhardt H, Ezquerra A, Grosmaire LS, Hamilton MJ, Hollemweguer E, Huang CA, Khanna KV, Kuebart G, Lackovic G, Ledbetter JA, Lee R, Llanes D, Lunney JK, McCullough KC, Molitor T, Nielsen J, Niewold TA, Pescovitz MD, de la Lastra JM, Rehakova Z, Salmon H, Schnitzlein WM, Seebach J, Simon A, Sinkora J, Sinkora M, Stokes CR, Summerfield A, Sver L, Thacker E, Valpotic I, Yang H, Zuckermann FA, Zwart R.

Vet Immunol Immunopathol. 2001 Jul 20;80(1-2):5-23.

PMID:
11445215
3.

A D-amino acid peptide inhibitor of NF-kappa B nuclear localization is efficacious in models of inflammatory disease.

Fujihara SM, Cleaveland JS, Grosmaire LS, Berry KK, Kennedy KA, Blake JJ, Loy J, Rankin BM, Ledbetter JA, Nadler SG.

J Immunol. 2000 Jul 15;165(2):1004-12.

4.

Construction, expression, and characterization of anticarcinoma sFv fused to IL-2 or GM-CSF.

Zhao L, Rai SK, Grosmaire LS, Ledbetter JA, Fell HP.

J Hematother Stem Cell Res. 1999 Aug;8(4):393-9.

PMID:
10634177
5.

Agonistic activity of a CD40-specific single-chain Fv constructed from the variable regions of mAb G28-5.

Ledbetter JA, Francisco JA, Siegall CB, Gilliland LK, Hollenbaugh D, Aruffo A, Siadak AW, Mischel-Petty N, Grosmaire LS, Gordon ML, Brown TJ, Moran-Davis P, Mittler RS, Kiener PA, Nadler SG.

Crit Rev Immunol. 1997;17(5-6):427-35. Review.

PMID:
9419430
6.

Intracellular CD22 rapidly moves to the cell surface in a tyrosine kinase-dependent manner following antigen receptor stimulation.

Sherbina NV, Linsley PS, Myrdal S, Grosmaire LS, Ledbetter JA, Schieven GL.

J Immunol. 1996 Nov 15;157(10):4390-8.

PMID:
8906814
7.

Surface expression of CD28 single chain Fv for costimulation by tumor cells.

Winberg G, Grosmaire LS, Klussman K, Hayden MS, Fell HP, Ledbetter JA, Mittler RS.

Immunol Rev. 1996 Oct;153:209-23. Review. No abstract available.

PMID:
9010725
8.

Costimulation by CD28 sFv expressed on the tumor cell surface or as a soluble bispecific molecule targeted to the L6 carcinoma antigen.

Hayden MS, Grosmaire LS, Norris NA, Gilliland LK, Winberg G, Tritschler D, Tsu TT, Linsley PS, Mittler RS, Senter PD, Fell HP, Ledbetter JA.

Tissue Antigens. 1996 Oct;48(4 Pt 1):242-54.

PMID:
8946677
9.

ZAP-70 and p72syk are signaling response elements through MHC class II molecules.

Kanner SB, Grosmaire LS, Blake J, Schieven GL, Masewicz S, Odum N, Ledbetter JA.

Tissue Antigens. 1995 Sep;46(3 ( Pt 1)):145-54.

PMID:
8525473
10.

Agonistic and antagonistic properties of CD40 mAb G28-5 are dependent on binding valency.

Ledbetter JA, Grosmaire LS, Hollenbaugh D, Aruffo A, Nadler SG.

Circ Shock. 1994 Oct;44(2):67-72.

PMID:
7743602
11.

The random inactivation of the X chromosome carrying the defective gene responsible for X-linked hyper IgM syndrome (X-HIM) in female carriers of HIGM1.

Hollenbaugh D, Wu LH, Ochs HD, Nonoyama S, Grosmaire LS, Ledbetter JA, Noelle RJ, Hill H, Aruffo A.

J Clin Invest. 1994 Aug;94(2):616-22.

12.

CD40 ligand expression is defective in a subset of patients with common variable immunodeficiency.

Farrington M, Grosmaire LS, Nonoyama S, Fischer SH, Hollenbaugh D, Ledbetter JA, Noelle RJ, Aruffo A, Ochs HD.

Proc Natl Acad Sci U S A. 1994 Feb 1;91(3):1099-103.

13.

Beta 2-integrin LFA-1 signaling through phospholipase C-gamma 1 activation.

Kanner SB, Grosmaire LS, Ledbetter JA, Damle NK.

Proc Natl Acad Sci U S A. 1993 Aug 1;90(15):7099-103.

14.

CD4, CD8 and the role of CD45 in T-cell activation.

Ledbetter JA, Deans JP, Aruffo A, Grosmaire LS, Kanner SB, Bolen JB, Schieven GL.

Curr Opin Immunol. 1993 Jun;5(3):334-40. Review.

PMID:
8347296
15.

The CD40 ligand, gp39, is defective in activated T cells from patients with X-linked hyper-IgM syndrome.

Aruffo A, Farrington M, Hollenbaugh D, Li X, Milatovich A, Nonoyama S, Bajorath J, Grosmaire LS, Stenkamp R, Neubauer M, et al.

Cell. 1993 Jan 29;72(2):291-300.

PMID:
7678782
16.

The human T cell antigen gp39, a member of the TNF gene family, is a ligand for the CD40 receptor: expression of a soluble form of gp39 with B cell co-stimulatory activity.

Hollenbaugh D, Grosmaire LS, Kullas CD, Chalupny NJ, Braesch-Andersen S, Noelle RJ, Stamenkovic I, Ledbetter JA, Aruffo A.

EMBO J. 1992 Dec;11(12):4313-21.

17.

Signal transduction by HLA-DR is mediated by tyrosine kinase(s) and regulated by CD45 in activated T cells.

Odum N, Martin PJ, Schieven GL, Norris NA, Grosmaire LS, Hansen JA, Ledbetter JA.

Hum Immunol. 1991 Oct;32(2):85-94.

PMID:
1835971
18.

CTLA-4 is a second receptor for the B cell activation antigen B7.

Linsley PS, Brady W, Urnes M, Grosmaire LS, Damle NK, Ledbetter JA.

J Exp Med. 1991 Sep 1;174(3):561-9.

19.

Tyrosine phosphorylation regulates phospholipase C activation in human T-cells.

Ledbetter JA, Grosmaire LS, Tsu TT, Schieven GL.

Biochem Soc Trans. 1991 Apr;19(2):269-72. No abstract available.

PMID:
1679729
20.

CD28 ligation in T-cell activation: evidence for two signal transduction pathways.

Ledbetter JA, Imboden JB, Schieven GL, Grosmaire LS, Rabinovitch PS, Lindsten T, Thompson CB, June CH.

Blood. 1990 Apr 1;75(7):1531-9.

21.

CD45 ligation in T cells regulates signal transduction through both the interleukin-2 receptor and the CD3/Ti T-cell receptor complex.

Gilliland LK, Schieven GL, Grosmaire LS, Damle NK, Ledbetter JA.

Tissue Antigens. 1990 Mar;35(3):128-35.

PMID:
2142837
22.

Signal transduction in lymphocyte activation through crosslinking of HLA class I molecules.

Gilliland LK, Norris NA, Grosmaire LS, Ferrone S, Gladstone P, Ledbetter JA.

Hum Immunol. 1989 Aug;25(4):269-89.

PMID:
2475477
23.

Enhanced transmembrane signalling activity of monoclonal antibody heteroconjugates suggests molecular interactions between receptors on the T cell surface.

Ledbetter JA, Norris NA, Grossmann A, Grosmaire LS, June CH, Uckun FM, Cosand WL, Rabinovitch PS.

Mol Immunol. 1989 Feb;26(2):137-45.

PMID:
2918858
24.

Role of CD2 cross-linking in cytoplasmic calcium responses and T cell activation.

Ledbetter JA, Rabinovitch PS, Hellström I, Hellström KE, Grosmaire LS, June CH.

Eur J Immunol. 1988 Oct;18(10):1601-8.

PMID:
2461308
25.

Lysis of cells infected with HIV-1 by human lymphocytes targeted with monoclonal antibody heteroconjugates.

Zarling JM, Moran PA, Grosmaire LS, McClure J, Shriver K, Ledbetter JA.

J Immunol. 1988 Apr 15;140(8):2609-13.

PMID:
2965725
26.
27.

An immunoglobulin light chain dimer with CD4 antigen specificity.

Ledbetter JA, Fell HP, Grosmaire LS, Norris NA, Tsu TT.

Mol Immunol. 1987 Dec;24(12):1255-61.

PMID:
2448606
28.

Selective removal of antigen-complexed IgG from cat plasma by adsorption onto a protein A-silica matrix.

Snyder HW Jr, Ernst NR, Grosmaire LS, Balint JP, Yoshida LH, Jones FR.

J Immunol Methods. 1987 Aug 3;101(2):209-17.

PMID:
3039006
29.

Crosslinking of surface antigens causes mobilization of intracellular ionized calcium in T lymphocytes.

Ledbetter JA, June CH, Grosmaire LS, Rabinovitch PS.

Proc Natl Acad Sci U S A. 1987 Mar;84(5):1384-8.

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