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Recommendations for the Nonpharmacological Treatment of Apathy in Brain Disorders.

Manera V, Abrahams S, Agüera-Ortiz L, Bremond F, David R, Fairchild K, Gros A, Hanon C, Husain M, König A, Lockwood PL, Pino M, Radakovic R, Robert G, Slachevsky A, Stella F, Tribouillard A, Trimarchi PD, Verhey F, Yesavage J, Zeghari R, Robert P.

Am J Geriatr Psychiatry. 2019 Aug 9. pii: S1064-7481(19)30459-2. doi: 10.1016/j.jagp.2019.07.014. [Epub ahead of print]


A genome-wide RNAi screen reveals essential therapeutic targets of breast cancer stem cells.

Arfaoui A, Rioualen C, Azzoni V, Pinna G, Finetti P, Wicinski J, Josselin E, Macario M, Castellano R, Léonard-Stumpf C, Bal A, Gros A, Lossy S, Kharrat M, Collette Y, Bertucci F, Birnbaum D, Douik H, Bidaut G, Charafe-Jauffret E, Ginestier C.

EMBO Mol Med. 2019 Sep 2:e9930. doi: 10.15252/emmm.201809930. [Epub ahead of print]


Determinants for Neoantigen Identification.

Garcia-Garijo A, Fajardo CA, Gros A.

Front Immunol. 2019 Jun 24;10:1392. doi: 10.3389/fimmu.2019.01392. eCollection 2019. Review.


Mutations of the B-cell receptor pathway confer chemoresistance in primary cutaneous diffuse large B-cell lymphoma leg-type.

Ducharme O, Beylot-Barry M, Pham-Ledard A, Bohers E, Viailly PJ, Bandres T, Faur N, Frison E, Vergier B, Jardin F, Merlio JP, Gros A.

J Invest Dermatol. 2019 May 28. pii: S0022-202X(19)31572-6. doi: 10.1016/j.jid.2019.05.008. [Epub ahead of print]


The authors reply.

Dupuis C, Gros A, Ruckly S, Darmon M, Timsit JF.

Crit Care Med. 2019 Jan;47(1):e64-e66. doi: 10.1097/CCM.0000000000003484. No abstract available.


Enhanced detection of neoantigen-reactive T cells targeting unique and shared oncogenes for personalized cancer immunotherapy.

Yossef R, Tran E, Deniger DC, Gros A, Pasetto A, Parkhurst MR, Gartner JJ, Prickett TD, Cafri G, Robbins PF, Rosenberg SA.

JCI Insight. 2018 Oct 4;3(19). pii: 122467. doi: 10.1172/jci.insight.122467.


Sex ratio in dementia with Lewy bodies balanced between Alzheimer's disease and Parkinson's disease dementia: a cross-sectional study.

Mouton A, Blanc F, Gros A, Manera V, Fabre R, Sauleau E, Gomez-Luporsi I, Tifratene K, Friedman L, Thümmler S, Pradier C, Robert PH, David R.

Alzheimers Res Ther. 2018 Sep 12;10(1):92. doi: 10.1186/s13195-018-0417-4.


Association Between Body Weight Variation and Survival and Other Adverse Events in Critically Ill Patients With Shock: A Multicenter Cohort Study of the OUTCOMEREA Network.

Gros A, Dupuis C, Ruckly S, Lautrette A, Garrouste-Orgeas M, Gainnier M, Forel JM, Marcotte G, Azoulay E, Cohen Y, Schwebel C, Argaud L, de Montmollin E, Siami S, Goldgran-Toledano D, Darmon M, Timsit JF; OUTCOMEREA Study Group.

Crit Care Med. 2018 Oct;46(10):e981-e987. doi: 10.1097/CCM.0000000000003338.


Clinical, histological and molecular predictors of metastatic melanoma responses to anti-PD-1 immunotherapy.

Dupuis F, Lamant L, Gerard E, Torossian N, Chaltiel L, Filleron T, Beylot-Barry M, Dutriaux C, Prey S, Gros A, Jullie ML, Meyer N, Vergier B.

Br J Cancer. 2018 Jul;119(2):193-199. doi: 10.1038/s41416-018-0168-9. Epub 2018 Jul 5.


Behavioral tagging and capture: long-term memory decline in middle-aged rats.

Gros A, Wang SH.

Neurobiol Aging. 2018 Jul;67:31-41. doi: 10.1016/j.neurobiolaging.2018.02.023. Epub 2018 Mar 10.


A Single-Arm Phase II Trial of Lenalidomide in Relapsing or Refractory Primary Cutaneous Large B-Cell Lymphoma, Leg Type.

Beylot-Barry M, Mermin D, Maillard A, Bouabdallah R, Bonnet N, Duval-Modeste AB, Mortier L, Ingen-Housz-Oro S, Ram-Wolff C, Barete S, Dalle S, Maubec E, Quereux G, Templier I, Bagot M, Grange F, Joly P, Vergier B, Vially PJ, Gros A, Pham-Ledard A, Frison E, Merlio JP.

J Invest Dermatol. 2018 Sep;138(9):1982-1989. doi: 10.1016/j.jid.2018.03.1516. Epub 2018 Mar 27.


Double-hit or dual expression of MYC and BCL2 in primary cutaneous large B-cell lymphomas.

Menguy S, Frison E, Prochazkova-Carlotti M, Dalle S, Dereure O, Boulinguez S, Dalac S, Machet L, Ram-Wolff C, Verneuil L, Gros A, Vergier B, Beylot-Barry M, Merlio JP, Pham-Ledard A.

Mod Pathol. 2018 Aug;31(8):1332-1342. doi: 10.1038/s41379-018-0041-7. Epub 2018 Mar 26.


The contribution of platelet glycoprotein receptors to inflammatory bleeding prevention is stimulus and organ dependent.

Rayes J, Jadoui S, Lax S, Gros A, Wichaiyo S, Ollivier V, Denis CV, Ware J, Nieswandt B, Jandrot-Perrus M, Watson SP, Ho-Tin-Noé B.

Haematologica. 2018 Jun;103(6):e256-e258. doi: 10.3324/haematol.2017.182162. Epub 2018 Feb 1. No abstract available.


Mosaic NRASopathy n a child with giant melanocytic congenital naevus, epidermal hamartoma and bilateral nephroblastomatosis: clinical implication for follow-up.

Maridet C, Morice-Picard F, Gros A, Crivelli L, de la Fouchardière A, Vergier B, Taïeb A.

J Eur Acad Dermatol Venereol. 2018 Jul;32(7):e258-e260. doi: 10.1111/jdv.14780. Epub 2018 Mar 13. No abstract available.


Recommendations for the Use of Serious Games in Neurodegenerative Disorders: 2016 Delphi Panel.

Manera V, Ben-Sadoun G, Aalbers T, Agopyan H, Askenazy F, Benoit M, Bensamoun D, Bourgeois J, Bredin J, Bremond F, Crispim-Junior C, David R, De Schutter B, Ettore E, Fairchild J, Foulon P, Gazzaley A, Gros A, Hun S, Knoefel F, Olde Rikkert M, Phan Tran MK, Politis A, Rigaud AS, Sacco G, Serret S, Thümmler S, Welter ML, Robert P.

Front Psychol. 2017 Jul 25;8:1243. doi: 10.3389/fpsyg.2017.01243. eCollection 2017.


Assessment of BRAFV600E mutation in pulmonary Langerhans cell histiocytosis in tissue biopsies and bronchoalveolar lavages by droplet digital polymerase chain reaction.

Pierry C, Caumont C, Blanchard E, Brochet C, Dournes G, Gros A, Bandres T, Verdon S, Marty M, Bégueret H, Merlio JP.

Virchows Arch. 2018 Feb;472(2):247-258. doi: 10.1007/s00428-017-2185-0. Epub 2017 Jul 15.


Extubation Success Prediction in a Multicentric Cohort of Patients with Severe Brain Injury.

Asehnoune K, Seguin P, Lasocki S, Roquilly A, Delater A, Gros A, Denou F, Mahé PJ, Nesseler N, Demeure-Dit-Latte D, Launey Y, Lakhal K, Rozec B, Mallédant Y, Sébille V, Jaber S, Le Thuaut A, Feuillet F, Cinotti R; ATLANREA group.

Anesthesiology. 2017 Aug;127(2):338-346. doi: 10.1097/ALN.0000000000001725.


[The tenth gene of HIV].

Cassan É, Arigon-Chifolleau AM, Mesnard JM, Gros A, Gascuel O.

Med Sci (Paris). 2017 May;33(5):484-485. doi: 10.1051/medsci/20173305008. Epub 2017 Jun 14. French. No abstract available.


Antipsychotic prescribing for Alzheimer's disease and related disorders in specialized settings from 2010 to 2014 in France: a repeated cross-sectional study.

Tifratene K, Manera V, Fabre R, Gros A, Thummler S, Pradier C, Robert P, David R.

Alzheimers Res Ther. 2017 Apr 26;9(1):34. doi: 10.1186/s13195-017-0256-8.


Olfactory disturbances in ageing with and without dementia: towards new diagnostic tools.

Gros A, Manera V, De March CA, Guevara N, König A, Friedman L, Robert P, Golebiowski J, David R.

J Laryngol Otol. 2017 Jul;131(7):572-579. doi: 10.1017/S0022215117000858. Epub 2017 Apr 20.


TP53 alterations in primary and secondary Sézary syndrome: A diagnostic tool for the assessment of malignancy in patients with erythroderma.

Gros A, Laharanne E, Vergier M, Prochazkova-Carlotti M, Pham-Ledard A, Bandres T, Poglio S, Berhouet S, Vergier B, Vial JP, Chevret E, Beylot-Barry M, Merlio JP.

PLoS One. 2017 Mar 16;12(3):e0173171. doi: 10.1371/journal.pone.0173171. eCollection 2017.


miR-600 Acts as a Bimodal Switch that Regulates Breast Cancer Stem Cell Fate through WNT Signaling.

El Helou R, Pinna G, Cabaud O, Wicinski J, Bhajun R, Guyon L, Rioualen C, Finetti P, Gros A, Mari B, Barbry P, Bertucci F, Bidaut G, Harel-Bellan A, Birnbaum D, Charafe-Jauffret E, Ginestier C.

Cell Rep. 2017 Feb 28;18(9):2256-2268. doi: 10.1016/j.celrep.2017.02.016.


The expanding role of immunotherapy.

Martin-Liberal J, Ochoa de Olza M, Hierro C, Gros A, Rodon J, Tabernero J.

Cancer Treat Rev. 2017 Mar;54:74-86. doi: 10.1016/j.ctrv.2017.01.008. Epub 2017 Feb 11. Review.


Impact of transfusion on patients with sepsis admitted in intensive care unit: a systematic review and meta-analysis.

Dupuis C, Sonneville R, Adrie C, Gros A, Darmon M, Bouadma L, Timsit JF.

Ann Intensive Care. 2017 Dec;7(1):5. doi: 10.1186/s13613-016-0226-5. Epub 2017 Jan 4. Review.


Hybridization Capture-Based Next-Generation Sequencing to Evaluate Coding Sequence and Deep Intronic Mutations in the NF1 Gene.

Cunha KS, Oliveira NS, Fausto AK, de Souza CC, Gros A, Bandres T, Idrissi Y, Merlio JP, de Moura Neto RS, Silva R, Geller M, Cappellen D.

Genes (Basel). 2016 Dec 17;7(12). pii: E133. doi: 10.3390/genes7120133.


Optimization of Positive End-Expiratory Pressure Targeting the Best Arterial Oxygen Transport in the Acute Respiratory Distress Syndrome: The OPTIPEP Study.

Chimot L, Fedun Y, Gacouin A, Campillo B, Marqué S, Gros A, Delour P, Bedon-Carte S, Le Tulzo Y.

ASAIO J. 2017 Jul/Aug;63(4):450-455. doi: 10.1097/MAT.0000000000000496.


Recommendations for the Use of ICT in Elderly Populations with Affective Disorders.

Gros A, Bensamoun D, Manera V, Fabre R, Zacconi-Cauvin AM, Thummler S, Benoit M, Robert P, David R.

Front Aging Neurosci. 2016 Nov 8;8:269. eCollection 2016.


Isolation of T-Cell Receptors Specifically Reactive with Mutated Tumor-Associated Antigens from Tumor-Infiltrating Lymphocytes Based on CD137 Expression.

Parkhurst M, Gros A, Pasetto A, Prickett T, Crystal JS, Robbins P, Rosenberg SA.

Clin Cancer Res. 2017 May 15;23(10):2491-2505. doi: 10.1158/1078-0432.CCR-16-2680. Epub 2016 Nov 8.


Invasion history and demographic processes associated with rapid morphological changes in the Red-whiskered bulbul established on tropical islands.

Le Gros A, Clergeau P, Zuccon D, Cornette R, Mathys B, Samadi S.

Mol Ecol. 2016 Nov;25(21):5359-5376. doi: 10.1111/mec.13853. Epub 2016 Oct 11.


[Neuropsychiatric disorders and technological solutions].

Bensamoun D, Gros A, Manera V, König A, Guérin O, Robert P, David R.

Soins Gerontol. 2016 Sep-Oct;21(121):18-20. doi: 10.1016/j.sger.2016.07.005. French.


Ionic immune suppression within the tumour microenvironment limits T cell effector function.

Eil R, Vodnala SK, Clever D, Klebanoff CA, Sukumar M, Pan JH, Palmer DC, Gros A, Yamamoto TN, Patel SJ, Guittard GC, Yu Z, Carbonaro V, Okkenhaug K, Schrump DS, Linehan WM, Roychoudhuri R, Restifo NP.

Nature. 2016 Sep 22;537(7621):539-543. doi: 10.1038/nature19364. Epub 2016 Sep 14.


Challenging a dogma: co-mutations exist in MAPK pathway genes in colorectal cancer.

Grellety T, Gros A, Pedeutour F, Merlio JP, Duranton-Tanneur V, Italiano A, Soubeyran I.

Virchows Arch. 2016 Oct;469(4):459-64. doi: 10.1007/s00428-016-1991-0. Epub 2016 Jul 11.


Tumor- and Neoantigen-Reactive T-cell Receptors Can Be Identified Based on Their Frequency in Fresh Tumor.

Pasetto A, Gros A, Robbins PF, Deniger DC, Prickett TD, Matus-Nicodemos R, Douek DC, Howie B, Robins H, Parkhurst MR, Gartner J, Trebska-McGowan K, Crystal JS, Rosenberg SA.

Cancer Immunol Res. 2016 Sep 2;4(9):734-43. doi: 10.1158/2326-6066.CIR-16-0001. Epub 2016 Jun 28.


Durable Complete Response from Metastatic Melanoma after Transfer of Autologous T Cells Recognizing 10 Mutated Tumor Antigens.

Prickett TD, Crystal JS, Cohen CJ, Pasetto A, Parkhurst MR, Gartner JJ, Yao X, Wang R, Gros A, Li YF, El-Gamil M, Trebska-McGowan K, Rosenberg SA, Robbins PF.

Cancer Immunol Res. 2016 Aug;4(8):669-78. doi: 10.1158/2326-6066.CIR-15-0215. Epub 2016 Jun 16.


Speed of leukemia development and genetic diversity in xenograft models of T cell acute lymphoblastic leukemia.

Poglio S, Lewandowski D, Calvo J, Caye A, Gros A, Laharanne E, Leblanc T, Landman-Parker J, Baruchel A, Soulier J, Ballerini P, Clappier E, Pflumio F.

Oncotarget. 2016 Jul 5;7(27):41599-41611. doi: 10.18632/oncotarget.9313.


MYD88 Somatic Mutation Is a Diagnostic Criterion in Primary Cutaneous Large B-Cell Lymphoma.

Menguy S, Gros A, Pham-Ledard A, Battistella M, Ortonne N, Comoz F, Balme B, Szablewski V, Lamant L, Carlotti A, Lorton MH, de Muret A, Le Gall F, Franck F, Croue A, Cappellen D, Beylot-Barry M, Merlio JP, Vergier B.

J Invest Dermatol. 2016 Aug;136(8):1741-1744. doi: 10.1016/j.jid.2016.04.018. Epub 2016 May 14. No abstract available.


Spleen Histologic Appearance in Common Variable Immunodeficiency: Analysis of 17 Cases.

Furudoï A, Gros A, Stanislas S, Hamidou M, Furudoï E, Oksenhendler É, Merlio JP, Viallard JF, Parrens M.

Am J Surg Pathol. 2016 Jul;40(7):958-67. doi: 10.1097/PAS.0000000000000661.


The Clock'N Test as a Possible Measure of Emotions: Normative Data Collected on a Non-clinical Population.

Gros A, Manera V, Daumas A, Guillemin S, Rouaud O, Martin ML, Giroud M, Béjot Y.

Front Behav Neurosci. 2016 Feb 5;10:8. doi: 10.3389/fnbeh.2016.00008. eCollection 2016.


Prospective identification of neoantigen-specific lymphocytes in the peripheral blood of melanoma patients.

Gros A, Parkhurst MR, Tran E, Pasetto A, Robbins PF, Ilyas S, Prickett TD, Gartner JJ, Crystal JS, Roberts IM, Trebska-McGowan K, Wunderlich JR, Yang JC, Rosenberg SA.

Nat Med. 2016 Apr;22(4):433-8. doi: 10.1038/nm.4051. Epub 2016 Feb 22.


Human epidermal growth factor receptor 3 in head and neck squamous cell carcinomas.

Rysman B, Mouawad F, Gros A, Lansiaux A, Chevalier D, Meignan S.

Head Neck. 2016 Apr;38 Suppl 1:E2412-8. doi: 10.1002/hed.24367. Epub 2016 Feb 2. Review.


[Brain and memory: new neurons to remember].

Gros A, Veyrac A, Laroche S.

Biol Aujourdhui. 2015;209(3):229-48. doi: 10.1051/jbio/2015028. Epub 2016 Jan 28. Review. French.


Neuroendocrine phenotype as an acquired resistance mechanism in ALK-rearranged lung adenocarcinoma.

Caumont C, Veillon R, Gros A, Laharanne E, Bégueret H, Merlio JP.

Lung Cancer. 2016 Feb;92:15-8. doi: 10.1016/j.lungcan.2015.12.001. Epub 2015 Dec 4.


Memory T cell-driven differentiation of naive cells impairs adoptive immunotherapy.

Klebanoff CA, Scott CD, Leonardi AJ, Yamamoto TN, Cruz AC, Ouyang C, Ramaswamy M, Roychoudhuri R, Ji Y, Eil RL, Sukumar M, Crompton JG, Palmer DC, Borman ZA, Clever D, Thomas SK, Patel S, Yu Z, Muranski P, Liu H, Wang E, Marincola FM, Gros A, Gattinoni L, Rosenberg SA, Siegel RM, Restifo NP.

J Clin Invest. 2016 Jan;126(1):318-34. doi: 10.1172/JCI81217. Epub 2015 Dec 14.


Primary digestive melanoma in association with tubular adenoma: a case report illustrating the distinction from metastatic colonic melanoma.

Furudoï A, Caumont C, Dutriaux C, Cappellen D, Goussot JF, Vergier B, Merlio C, Barberis C, Merlio JP, Gros A.

Hum Pathol. 2016 Feb;48:167-71. doi: 10.1016/j.humpath.2015.09.025. Epub 2015 Oct 9.


Immunogenicity of somatic mutations in human gastrointestinal cancers.

Tran E, Ahmadzadeh M, Lu YC, Gros A, Turcotte S, Robbins PF, Gartner JJ, Zheng Z, Li YF, Ray S, Wunderlich JR, Somerville RP, Rosenberg SA.

Science. 2015 Dec 11;350(6266):1387-90. doi: 10.1126/science.aad1253. Epub 2015 Oct 29.


Targeting of HPV-16+ Epithelial Cancer Cells by TCR Gene Engineered T Cells Directed against E6.

Draper LM, Kwong ML, Gros A, Stevanović S, Tran E, Kerkar S, Raffeld M, Rosenberg SA, Hinrichs CS.

Clin Cancer Res. 2015 Oct 1;21(19):4431-9. doi: 10.1158/1078-0432.CCR-14-3341.


Intravascular Complications of Central Venous Catheterization by Insertion Site.

Parienti JJ, Mongardon N, Mégarbane B, Mira JP, Kalfon P, Gros A, Marqué S, Thuong M, Pottier V, Ramakers M, Savary B, Seguin A, Valette X, Terzi N, Sauneuf B, Cattoir V, Mermel LA, du Cheyron D; 3SITES Study Group.

N Engl J Med. 2015 Sep 24;373(13):1220-9. doi: 10.1056/NEJMoa1500964.


Clinical and genomic analysis of a randomised phase II study evaluating anastrozole and fulvestrant in postmenopausal patients treated for large operable or locally advanced hormone-receptor-positive breast cancer.

Quenel-Tueux N, Debled M, Rudewicz J, MacGrogan G, Pulido M, Mauriac L, Dalenc F, Bachelot T, Lortal B, Breton-Callu C, Madranges N, de Lara CT, Fournier M, Bonnefoi H, Soueidan H, Nikolski M, Gros A, Daly C, Wood H, Rabbitts P, Iggo R.

Br J Cancer. 2015 Aug 11;113(4):585-94. doi: 10.1038/bjc.2015.247. Epub 2015 Jul 14.


A time estimation task as a possible measure of emotions: difference depending on the nature of the stimulus used.

Gros A, Giroud M, Bejot Y, Rouaud O, Guillemin S, Aboa Eboulé C, Manera V, Daumas A, Lemesle Martin M.

Front Behav Neurosci. 2015 Jun 11;9:143. doi: 10.3389/fnbeh.2015.00143. eCollection 2015.


Single platelets seal neutrophil-induced vascular breaches via GPVI during immune-complex-mediated inflammation in mice.

Gros A, Syvannarath V, Lamrani L, Ollivier V, Loyau S, Goerge T, Nieswandt B, Jandrot-Perrus M, Ho-Tin-Noé B.

Blood. 2015 Aug 20;126(8):1017-26. doi: 10.1182/blood-2014-12-617159. Epub 2015 Jun 2.

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