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Items: 1 to 50 of 217

1.

Recent Developments and Therapeutic Strategies against Hepatocellular Carcinoma.

Yarchoan M, Agarwal P, Villanueva A, Rao S, Dawson LA, Llovet JM, Finn RS, Groopman JD, El-Serag HB, Monga SP, Wang XW, Karin M, Schwartz RE, Tanabe KK, Roberts LR, Gunaratne PH, Tsung A, Brown KA, Lawrence TS, Salem R, Singal AG, Kim AK, Rabiee A, Resar L, Hoshida Y, He AR, Ghoshal K, Ryan PB, Jaffee EM, Guha C, Mishra L, Coleman CN, Ahmed MM.

Cancer Res. 2019 Sep 1;79(17):4326-4330. doi: 10.1158/0008-5472.CAN-19-0803.

PMID:
31481419
2.

Inflammation throughout pregnancy and fetal growth restriction in rural Nepal.

Sauder MW, Lee SE, Schulze KJ, Christian P, Wu LSF, Khatry SK, LeClerq SC, Adhikari RK, Groopman JD, West KP.

Epidemiol Infect. 2019 Aug 30;147:e258. doi: 10.1017/S0950268819001493.

PMID:
31469064
3.

Serum miR-182 is a predictive biomarker for dichotomization of risk of hepatocellular carcinoma in rats.

Livingstone MC, Johnson NM, Roebuck BD, Kensler TW, Groopman JD.

Mol Carcinog. 2019 Aug 2. doi: 10.1002/mc.23093. [Epub ahead of print]

PMID:
31373075
4.

Association between aflatoxin-albumin adduct levels and tortilla consumption in Guatemalan adults.

Kroker-Lobos MF, Alvarez CS, Rivera-Andrade A, Smith JW, Egner P, Torres O, Lazo M, Freedman ND, Guallar E, Graubard BI, McGlynn KA, Ramírez-Zea M, Groopman JD.

Toxicol Rep. 2019 May 22;6:465-471. doi: 10.1016/j.toxrep.2019.05.009. eCollection 2019.

5.

Association between Liver Fibrosis and Serum PSA among U.S. Men: National Health and Nutrition Examination Survey (NHANES), 2001-2010.

Wang A, Lazo M, Carter HB, Groopman JD, Nelson WG, Platz EA.

Cancer Epidemiol Biomarkers Prev. 2019 Aug;28(8):1331-1338. doi: 10.1158/1055-9965.EPI-19-0145. Epub 2019 Jun 3.

PMID:
31160348
6.

Qidong: a crucible for studies on liver cancer etiology and prevention.

Chen J, Zhu J, Wang G, Groopman JD, Kensler TW.

Cancer Biol Med. 2019 Feb;16(1):24-37. doi: 10.20892/j.issn.2095-3941.2018.0394.

7.

Highlight Article: Environmental health in the biology century: Transitions from population to personalized prevention.

Groopman JD.

Exp Biol Med (Maywood). 2019 Jun;244(9):728-733. doi: 10.1177/1535370219837903. Epub 2019 Mar 20.

PMID:
30895818
8.

Broccoli sprout beverage is safe for thyroid hormonal and autoimmune status: Results of a 12-week randomized trial.

Chartoumpekis DV, Ziros PG, Chen JG, Groopman JD, Kensler TW, Sykiotis GP.

Food Chem Toxicol. 2019 Apr;126:1-6. doi: 10.1016/j.fct.2019.02.004. Epub 2019 Feb 5.

PMID:
30735751
9.

High prevalence of non-alcoholic fatty liver disease and metabolic risk factors in Guatemala: A population-based study.

Rivera-Andrade A, Kroker-Lobos MF, Lazo M, Freedman ND, Smith JW, Torres O, McGlynn KA, Groopman JD, Guallar E, Ramirez-Zea M.

Nutr Metab Cardiovasc Dis. 2019 Feb;29(2):191-200. doi: 10.1016/j.numecd.2018.10.008. Epub 2018 Oct 31.

PMID:
30573307
10.

Aflatoxin-Guanine DNA Adducts and Oxidatively Induced DNA Damage in Aflatoxin-Treated Mice in Vivo as Measured by Liquid Chromatography-Tandem Mass Spectrometry with Isotope Dilution.

Coskun E, Jaruga P, Vartanian V, Erdem O, Egner PA, Groopman JD, Lloyd RS, Dizdaroglu M.

Chem Res Toxicol. 2019 Jan 22;32(1):80-89. doi: 10.1021/acs.chemrestox.8b00202. Epub 2018 Dec 19.

PMID:
30525498
11.

Intrahepatic Cholangiocarcinoma: Continuing Challenges and Translational Advances.

Sirica AE, Gores GJ, Groopman JD, Selaru FM, Strazzabosco M, Wei Wang X, Zhu AX.

Hepatology. 2019 Apr;69(4):1803-1815. doi: 10.1002/hep.30289. Epub 2019 Mar 25. Review.

PMID:
30251463
12.

Aflatoxin exposure in children living in Mirpur, Dhaka: data from MAL-ED companion study.

Mahfuz M, Alam MA, Fahim SM, Gazi MA, Raihan MJ, Hossain M, Egner PA, Bessong PO, Petri WA, Groopman JD, Ahmed T.

J Expo Sci Environ Epidemiol. 2019 Sep;29(5):655-662. doi: 10.1038/s41370-018-0066-5. Epub 2018 Sep 5.

PMID:
30185944
13.

Exposure to aflatoxin and fumonisin in children at risk for growth impairment in rural Tanzania.

Chen C, Mitchell NJ, Gratz J, Houpt ER, Gong Y, Egner PA, Groopman JD, Riley RT, Showker JL, Svensen E, Mduma ER, Patil CL, Wu F.

Environ Int. 2018 Jun;115:29-37. doi: 10.1016/j.envint.2018.03.001. Epub 2018 Mar 13.

14.

Qidong hepatitis B virus infection cohort: a 25-year prospective study in high risk area of primary liver cancer.

Chen T, Qian G, Fan C, Sun Y, Wang J, Lu P, Xue X, Wu Y, Zhang Q, Jin Y, Wu Y, Gan Y, Lu J, Kensler TW, Groopman JD, Tu H.

Hepatoma Res. 2018;4. pii: 4. doi: 10.20517/2394-5079.2017.50. Epub 2018 Jan 26.

15.

Aflatoxin and viral hepatitis exposures in Guatemala: Molecular biomarkers reveal a unique profile of risk factors in a region of high liver cancer incidence.

Smith JW, Kroker-Lobos MF, Lazo M, Rivera-Andrade A, Egner PA, Wedemeyer H, Torres O, Freedman ND, McGlynn KA, Guallar E, Groopman JD, Ramirez-Zea M.

PLoS One. 2017 Dec 13;12(12):e0189255. doi: 10.1371/journal.pone.0189255. eCollection 2017.

16.

Unique pulmonary immunotoxicological effects of urban PM are not recapitulated solely by carbon black, diesel exhaust or coal fly ash.

Gour N, Sudini K, Khalil SM, Rule AM, Lees P, Gabrielson E, Groopman JD, Lajoie S, Singh A.

Environ Res. 2018 Feb;161:304-313. doi: 10.1016/j.envres.2017.10.041. Epub 2017 Nov 24.

17.

Editor's Highlight: Pregnancy Alters Aflatoxin B1 Metabolism and Increases DNA Damage in Mouse Liver.

Sriwattanapong K, Slocum SL, Chawanthayatham S, Fedeles BI, Egner PA, Groopman JD, Satayavivad J, Croy RG, Essigmann JM.

Toxicol Sci. 2017 Nov 1;160(1):173-179. doi: 10.1093/toxsci/kfx171.

18.

NEIL1 protects against aflatoxin-induced hepatocellular carcinoma in mice.

Vartanian V, Minko IG, Chawanthayatham S, Egner PA, Lin YC, Earley LF, Makar R, Eng JR, Camp MT, Li L, Stone MP, Lasarev MR, Groopman JD, Croy RG, Essigmann JM, McCullough AK, Lloyd RS.

Proc Natl Acad Sci U S A. 2017 Apr 18;114(16):4207-4212. doi: 10.1073/pnas.1620932114. Epub 2017 Apr 3.

19.

Profound changes in miRNA expression during cancer initiation by aflatoxin B1 and their abrogation by the chemopreventive triterpenoid CDDO-Im.

Livingstone MC, Johnson NM, Roebuck BD, Kensler TW, Groopman JD.

Mol Carcinog. 2017 Nov;56(11):2382-2390. doi: 10.1002/mc.22635. Epub 2017 Sep 2.

20.

Aflatoxin exposure during the first 36 months of life was not associated with impaired growth in Nepalese children: An extension of the MAL-ED study.

Mitchell NJ, Hsu HH, Chandyo RK, Shrestha B, Bodhidatta L, Tu YK, Gong YY, Egner PA, Ulak M, Groopman JD, Wu F.

PLoS One. 2017 Feb 17;12(2):e0172124. doi: 10.1371/journal.pone.0172124. eCollection 2017.

21.

The Plasma Proteome Is Associated with Anthropometric Status of Undernourished Nepalese School-Aged Children.

Lee SE, Stewart CP, Schulze KJ, Cole RN, Wu LS, Yager JD, Groopman JD, Khatry SK, Adhikari RK, Christian P, West KP Jr.

J Nutr. 2017 Mar;147(3):304-313. doi: 10.3945/jn.116.243014. Epub 2017 Feb 1.

22.

Plasma Selenium Protein P Isoform 1 (SEPP1): A Predictor of Selenium Status in Nepalese Children Detected by Plasma Proteomics.

Schulze KJ, Cole RN, Chaerkady R, Wu LSF, Nonyane BAS, Lee SE, Yager JD, Groopman JD, Christian P, West KP Jr.

Int J Vitam Nutr Res. 2017 Sep;87(5-6):1-10. doi: 10.1024/0300-9831/a000256. Epub 2016 May 10.

PMID:
27164173
23.

Chronic aflatoxin exposure in children living in Bhaktapur, Nepal: Extension of the MAL-ED study.

Mitchell NJ, Riley RT, Egner PA, Groopman JD, Wu F.

J Expo Sci Environ Epidemiol. 2017 Jan;27(1):106-111. doi: 10.1038/jes.2015.87. Epub 2016 Jan 6.

PMID:
26732375
24.

A Plasma α-Tocopherome Can Be Identified from Proteins Associated with Vitamin E Status in School-Aged Children of Nepal.

West KP Jr, Cole RN, Shrestha S, Schulze KJ, Lee SE, Betz J, Nonyane BA, Wu LS, Yager JD, Groopman JD, Christian P.

J Nutr. 2015 Dec;145(12):2646-56. doi: 10.3945/jn.115.210682. Epub 2015 Oct 7.

25.

Dietary aflatoxin-induced stunting in a novel rat model: evidence for toxin-induced liver injury and hepatic growth hormone resistance.

Knipstein B, Huang J, Barr E, Sossenheimer P, Dietzen D, Egner PA, Groopman JD, Rudnick DA.

Pediatr Res. 2015 Aug;78(2):120-7. doi: 10.1038/pr.2015.84. Epub 2015 May 4.

26.

Serial Free Bisphenol A and Bisphenol A Glucuronide Concentrations in Neonates.

Nachman RM, Fox SD, Golden WC, Sibinga E, Groopman JD, Lees PS.

J Pediatr. 2015 Jul;167(1):64-9. doi: 10.1016/j.jpeds.2015.03.036. Epub 2015 Apr 25.

27.

Molecular characteristics of Hepatitis B and chronic liver disease in a cohort of HB carriers from Bamako, Mali.

Traoré F, Gormally E, Villar S, Friesen MD, Groopman JD, Vernet G, Diallo S, Hainaut P, Maiga MY.

BMC Infect Dis. 2015 Apr 11;15:180. doi: 10.1186/s12879-015-0916-x.

28.

Early Life Metabolism of Bisphenol A: A Systematic Review of the Literature.

Nachman RM, Hartle JC, Lees PS, Groopman JD.

Curr Environ Health Rep. 2014 Mar;1(1):90-100.

29.

Translational cancer research: balancing prevention and treatment to combat cancer globally.

Wild CP, Bucher JR, de Jong BW, Dillner J, von Gertten C, Groopman JD, Herceg Z, Holmes E, Holmila R, Olsen JH, Ringborg U, Scalbert A, Shibata T, Smith MT, Ulrich C, Vineis P, McLaughlin J.

J Natl Cancer Inst. 2014 Dec 16;107(1):353. doi: 10.1093/jnci/dju353. Print 2015 Jan.

30.

Sulforaphane, a cancer chemopreventive agent, induces pathways associated with membrane biosynthesis in response to tissue damage by aflatoxin B1.

Techapiesancharoenkij N, Fiala JL, Navasumrit P, Croy RG, Wogan GN, Groopman JD, Ruchirawat M, Essigmann JM.

Toxicol Appl Pharmacol. 2015 Jan 1;282(1):52-60. doi: 10.1016/j.taap.2014.11.004. Epub 2014 Nov 18.

31.

Aflatoxin exposure during the first 1000 days of life in rural South Asia assessed by aflatoxin B₁-lysine albumin biomarkers.

Groopman JD, Egner PA, Schulze KJ, Wu LS, Merrill R, Mehra S, Shamim AA, Ali H, Shaikh S, Gernand A, Khatry SK, LeClerq SC, West KP Jr, Christian P.

Food Chem Toxicol. 2014 Dec;74:184-9. doi: 10.1016/j.fct.2014.09.016. Epub 2014 Oct 13.

32.

Prenatal exposure of mice to the human liver carcinogen aflatoxin B1 reveals a critical window of susceptibility to genetic change.

Chawanthayatham S, Thiantanawat A, Egner PA, Groopman JD, Wogan GN, Croy RG, Essigmann JM.

Int J Cancer. 2015 Mar 15;136(6):1254-62. doi: 10.1002/ijc.29102. Epub 2014 Aug 7.

33.

Rapid and sustainable detoxication of airborne pollutants by broccoli sprout beverage: results of a randomized clinical trial in China.

Egner PA, Chen JG, Zarth AT, Ng DK, Wang JB, Kensler KH, Jacobson LP, Muñoz A, Johnson JL, Groopman JD, Fahey JW, Talalay P, Zhu J, Chen TY, Qian GS, Carmella SG, Hecht SS, Kensler TW.

Cancer Prev Res (Phila). 2014 Aug;7(8):813-823. doi: 10.1158/1940-6207.CAPR-14-0103. Epub 2014 Jun 9.

34.

Novel natural mutations in the hepatitis B virus reverse transcriptase domain associated with hepatocellular carcinoma.

Wu Y, Gan Y, Gao F, Zhao Z, Jin Y, Zhu Y, Sun Z, Wu H, Chen T, Wang J, Sun Y, Fan C, Xiang Y, Qian G, Groopman JD, Gu J, Tu H.

PLoS One. 2014 May 1;9(5):e94864. doi: 10.1371/journal.pone.0094864. eCollection 2014.

35.

Genetic or pharmacologic activation of Nrf2 signaling fails to protect against aflatoxin genotoxicity in hypersensitive GSTA3 knockout mice.

Kensler KH, Slocum SL, Chartoumpekis DV, Dolan PM, Johnson NM, Ilic Z, Crawford DR, Sell S, Groopman JD, Kensler TW, Egner PA.

Toxicol Sci. 2014 Jun;139(2):293-300. doi: 10.1093/toxsci/kfu056. Epub 2014 Mar 27.

36.

Complete protection against aflatoxin B(1)-induced liver cancer with a triterpenoid: DNA adduct dosimetry, molecular signature, and genotoxicity threshold.

Johnson NM, Egner PA, Baxter VK, Sporn MB, Wible RS, Sutter TR, Groopman JD, Kensler TW, Roebuck BD.

Cancer Prev Res (Phila). 2014 Jul;7(7):658-65. doi: 10.1158/1940-6207.CAPR-13-0430. Epub 2014 Mar 24.

37.

Public health impacts of foodborne mycotoxins.

Wu F, Groopman JD, Pestka JJ.

Annu Rev Food Sci Technol. 2014;5:351-72. doi: 10.1146/annurev-food-030713-092431. Epub 2014 Jan 9. Review.

PMID:
24422587
38.

Reduced aflatoxin exposure presages decline in liver cancer mortality in an endemic region of China.

Chen JG, Egner PA, Ng D, Jacobson LP, Muñoz A, Zhu YR, Qian GS, Wu F, Yuan JM, Groopman JD, Kensler TW.

Cancer Prev Res (Phila). 2013 Oct;6(10):1038-45. doi: 10.1158/1940-6207.CAPR-13-0168. Epub 2013 Aug 20.

39.

Reduced formation of depurinating estrogen-DNA adducts by sulforaphane or KEAP1 disruption in human mammary epithelial MCF-10A cells.

Yang L, Zahid M, Liao Y, Rogan EG, Cavalieri EL, Davidson NE, Yager JD, Visvanathan K, Groopman JD, Kensler TW.

Carcinogenesis. 2013 Nov;34(11):2587-92. doi: 10.1093/carcin/bgt246. Epub 2013 Jul 10.

40.

Association between TP53 R249S mutation and polymorphisms in TP53 intron 1 in hepatocellular carcinoma.

Ortiz-Cuaran S, Cox D, Villar S, Friesen MD, Durand G, Chabrier A, Khuhaprema T, Sangrajrang S, Ognjanovic S, Groopman JD, Hainaut P, Le Calvez-Kelm F.

Genes Chromosomes Cancer. 2013 Oct;52(10):912-9. doi: 10.1002/gcc.22086. Epub 2013 Jul 8.

PMID:
23836507
41.

Urinary free bisphenol A and bisphenol A-glucuronide concentrations in newborns.

Nachman RM, Fox SD, Golden WC, Sibinga E, Veenstra TD, Groopman JD, Lees PS.

J Pediatr. 2013 Apr;162(4):870-2. doi: 10.1016/j.jpeds.2012.11.083. Epub 2013 Jan 11.

42.

Statistical inference from multiple iTRAQ experiments without using common reference standards.

Herbrich SM, Cole RN, West KP Jr, Schulze K, Yager JD, Groopman JD, Christian P, Wu L, O'Meally RN, May DH, McIntosh MW, Ruczinski I.

J Proteome Res. 2013 Feb 1;12(2):594-604. doi: 10.1021/pr300624g. Epub 2013 Jan 16.

43.

Association between HBX status, aflatoxin-induced R249S TP53 mutation and risk of hepatocellular carcinoma in a case-control study from Thailand.

Ortiz-Cuaran S, Villar S, Gouas D, Ferro G, Plymoth A, Khuhaprema T, Kalalak A, Sangrajrang S, Friesen MD, Groopman JD, Hainaut P.

Cancer Lett. 2013 Apr 30;331(1):46-51. doi: 10.1016/j.canlet.2012.11.012. Epub 2012 Nov 27.

PMID:
23200676
44.

Keap1-nrf2 signaling: a target for cancer prevention by sulforaphane.

Kensler TW, Egner PA, Agyeman AS, Visvanathan K, Groopman JD, Chen JG, Chen TY, Fahey JW, Talalay P.

Top Curr Chem. 2013;329:163-77. doi: 10.1007/128_2012_339. Review.

45.

Aflatoxin-induced TP53 R249S mutation in hepatocellular carcinoma in Thailand: association with tumors developing in the absence of liver cirrhosis.

Villar S, Ortiz-Cuaran S, Abedi-Ardekani B, Gouas D, Nogueira da Costa A, Plymoth A, Khuhaprema T, Kalalak A, Sangrajrang S, Friesen MD, Groopman JD, Hainaut P.

PLoS One. 2012;7(6):e37707. doi: 10.1371/journal.pone.0037707. Epub 2012 Jun 4.

46.

A single neonatal exposure to aflatoxin b1 induces prolonged genetic damage in two loci of mouse liver.

Wattanawaraporn R, Woo LL, Belanger C, Chang SC, Adams JE, Trudel LJ, Bouhenguel JT, Egner PA, Groopman JD, Croy RG, Essigmann JM, Wogan GN.

Toxicol Sci. 2012 Aug;128(2):326-33. doi: 10.1093/toxsci/kfs151. Epub 2012 Apr 26.

47.

Maternal serum proteome changes between the first and third trimester of pregnancy in rural southern Nepal.

Scholl PF, Cole RN, Ruczinski I, Gucek M, Diez R, Rennie A, Nathasingh C, Schulze K, Christian P, Yager JD, Groopman JD, West KP Jr.

Placenta. 2012 May;33(5):424-32. doi: 10.1016/j.placenta.2012.02.009. Epub 2012 Mar 3.

48.

Modulation of the metabolism of airborne pollutants by glucoraphanin-rich and sulforaphane-rich broccoli sprout beverages in Qidong, China.

Kensler TW, Ng D, Carmella SG, Chen M, Jacobson LP, Muñoz A, Egner PA, Chen JG, Qian GS, Chen TY, Fahey JW, Talalay P, Groopman JD, Yuan JM, Hecht SS.

Carcinogenesis. 2012 Jan;33(1):101-7. doi: 10.1093/carcin/bgr229. Epub 2011 Nov 1. Erratum in: Carcinogenesis. 2012 Mar;33(3):722.

49.

Seasonal variation in TP53 R249S-mutated serum DNA with aflatoxin exposure and hepatitis B virus infection.

Villar S, Le Roux-Goglin E, Gouas DA, Plymoth A, Ferro G, Boniol M, Lereau M, Bah E, Hall AJ, Wild CP, Mendy M, Norder H, van der Sande M, Whittle H, Friesen MD, Groopman JD, Hainaut P.

Environ Health Perspect. 2011 Nov;119(11):1635-40. doi: 10.1289/ehp.1103539. Epub 2011 Jul 18.

50.

Present and future directions of translational research on aflatoxin and hepatocellular carcinoma. A review.

Wogan GN, Kensler TW, Groopman JD.

Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2012;29(2):249-57. doi: 10.1080/19440049.2011.563370. Epub 2011 Jun 1. Review.

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