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Items: 16

1.

ARv7 Represses Tumor-Suppressor Genes in Castration-Resistant Prostate Cancer.

Cato L, de Tribolet-Hardy J, Lee I, Rottenberg JT, Coleman I, Melchers D, Houtman R, Xiao T, Li W, Uo T, Sun S, Kuznik NC, Göppert B, Ozgun F, van Royen ME, Houtsmuller AB, Vadhi R, Rao PK, Li L, Balk SP, Den RB, Trock BJ, Karnes RJ, Jenkins RB, Klein EA, Davicioni E, Gruhl FJ, Long HW, Liu XS, Cato ACB, Lack NA, Nelson PS, Plymate SR, Groner AC, Brown M.

Cancer Cell. 2019 Mar 18;35(3):401-413.e6. doi: 10.1016/j.ccell.2019.01.008. Epub 2019 Feb 14.

PMID:
30773341
2.

Role of steroid receptor and coregulator mutations in hormone-dependent cancers.

Groner AC, Brown M.

J Clin Invest. 2017 Apr 3;127(4):1126-1135. doi: 10.1172/JCI88885. Epub 2017 Apr 3. Review.

3.

Enhancer-Mediated Oncogenic Function of the Menin Tumor Suppressor in Breast Cancer.

Dreijerink KMA, Groner AC, Vos ESM, Font-Tello A, Gu L, Chi D, Reyes J, Cook J, Lim E, Lin CY, de Laat W, Rao PK, Long HW, Brown M.

Cell Rep. 2017 Mar 7;18(10):2359-2372. doi: 10.1016/j.celrep.2017.02.025.

4.

Targeting transcriptional co-activators in advanced prostate cancer.

Groner AC, Brown M, Theurillat JP.

Cell Cycle. 2016 Dec 16;15(24):3333-3334. doi: 10.1080/15384101.2016.1229019. Epub 2016 Sep 9. No abstract available.

5.

PI3K/AKT Signaling Regulates H3K4 Methylation in Breast Cancer.

Spangle JM, Dreijerink KM, Groner AC, Cheng H, Ohlson CE, Reyes J, Lin CY, Bradner J, Zhao JJ, Roberts TM, Brown M.

Cell Rep. 2016 Jun 21;15(12):2692-704. doi: 10.1016/j.celrep.2016.05.046. Epub 2016 Jun 9.

6.

TRIM24 Is an Oncogenic Transcriptional Activator in Prostate Cancer.

Groner AC, Cato L, de Tribolet-Hardy J, Bernasocchi T, Janouskova H, Melchers D, Houtman R, Cato ACB, Tschopp P, Gu L, Corsinotti A, Zhong Q, Fankhauser C, Fritz C, Poyet C, Wagner U, Guo T, Aebersold R, Garraway LA, Wild PJ, Theurillat JP, Brown M.

Cancer Cell. 2016 Jun 13;29(6):846-858. doi: 10.1016/j.ccell.2016.04.012. Epub 2016 May 26.

7.

Venus trap in the mouse embryo reveals distinct molecular dynamics underlying specification of first embryonic lineages.

Dietrich JE, Panavaite L, Gunther S, Wennekamp S, Groner AC, Pigge A, Salvenmoser S, Trono D, Hufnagel L, Hiiragi T.

EMBO Rep. 2015 Aug;16(8):1005-21. doi: 10.15252/embr.201540162. Epub 2015 Jul 3.

8.

A relative shift in cloacal location repositions external genitalia in amniote evolution.

Tschopp P, Sherratt E, Sanger TJ, Groner AC, Aspiras AC, Hu JK, Pourquié O, Gros J, Tabin CJ.

Nature. 2014 Dec 18;516(7531):391-4. doi: 10.1038/nature13819. Epub 2014 Nov 5.

9.

Prostate cancer. Ubiquitylome analysis identifies dysregulation of effector substrates in SPOP-mutant prostate cancer.

Theurillat JP, Udeshi ND, Errington WJ, Svinkina T, Baca SC, Pop M, Wild PJ, Blattner M, Groner AC, Rubin MA, Moch H, Prive GG, Carr SA, Garraway LA.

Science. 2014 Oct 3;346(6205):85-89. doi: 10.1126/science.1250255. Epub 2014 Oct 2.

10.

EZH2 oncogenic activity in castration-resistant prostate cancer cells is Polycomb-independent.

Xu K, Wu ZJ, Groner AC, He HH, Cai C, Lis RT, Wu X, Stack EC, Loda M, Liu T, Xu H, Cato L, Thornton JE, Gregory RI, Morrissey C, Vessella RL, Montironi R, Magi-Galluzzi C, Kantoff PW, Balk SP, Liu XS, Brown M.

Science. 2012 Dec 14;338(6113):1465-9. doi: 10.1126/science.1227604.

11.

The Krüppel-associated box repressor domain can induce reversible heterochromatization of a mouse locus in vivo.

Groner AC, Tschopp P, Challet L, Dietrich JE, Verp S, Offner S, Barde I, Rodriguez I, Hiiragi T, Trono D.

J Biol Chem. 2012 Jul 20;287(30):25361-9. doi: 10.1074/jbc.M112.350884. Epub 2012 May 17.

12.

A gene-rich, transcriptionally active environment and the pre-deposition of repressive marks are predictive of susceptibility to KRAB/KAP1-mediated silencing.

Meylan S, Groner AC, Ambrosini G, Malani N, Quenneville S, Zangger N, Kapopoulou A, Kauzlaric A, Rougemont J, Ciuffi A, Bushman FD, Bucher P, Trono D.

BMC Genomics. 2011 Jul 26;12:378. doi: 10.1186/1471-2164-12-378.

13.

Genetic reactivation of cone photoreceptors restores visual responses in retinitis pigmentosa.

Busskamp V, Duebel J, Balya D, Fradot M, Viney TJ, Siegert S, Groner AC, Cabuy E, Forster V, Seeliger M, Biel M, Humphries P, Paques M, Mohand-Said S, Trono D, Deisseroth K, Sahel JA, Picaud S, Roska B.

Science. 2010 Jul 23;329(5990):413-7. doi: 10.1126/science.1190897. Epub 2010 Jun 24.

14.

KRAB-zinc finger proteins and KAP1 can mediate long-range transcriptional repression through heterochromatin spreading.

Groner AC, Meylan S, Ciuffi A, Zangger N, Ambrosini G, Dénervaud N, Bucher P, Trono D.

PLoS Genet. 2010 Mar 5;6(3):e1000869. doi: 10.1371/journal.pgen.1000869.

15.

Regulation of episomal gene expression by KRAB/KAP1-mediated histone modifications.

Barde I, Laurenti E, Verp S, Groner AC, Towne C, Padrun V, Aebischer P, Trumpp A, Trono D.

J Virol. 2009 Jun;83(11):5574-80. doi: 10.1128/JVI.00001-09. Epub 2009 Mar 11.

16.

KAP1-mediated epigenetic repression in the forebrain modulates behavioral vulnerability to stress.

Jakobsson J, Cordero MI, Bisaz R, Groner AC, Busskamp V, Bensadoun JC, Cammas F, Losson R, Mansuy IM, Sandi C, Trono D.

Neuron. 2008 Dec 10;60(5):818-31. doi: 10.1016/j.neuron.2008.09.036.

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