Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 226

1.

Bioactivation mechanisms of N-hydroxyaristolactams: Nitroreduction metabolites of aristolochic acids.

Okuno Y, Bonala R, Attaluri S, Johnson F, Grollman AP, Sidorenko VS, Oda Y.

Environ Mol Mutagen. 2019 Aug 2. doi: 10.1002/em.22321. [Epub ahead of print]

PMID:
31374128
2.

Correction: Non-invasive detection of urothelial cancer through the analysis of driver gene mutations and aneuploidy.

Springer SU, Chen CH, Rodriguez Pena MDC, Li L, Douville C, Wang Y, Cohen JD, Taheri D, Silliman N, Schaefer J, Ptak J, Dobbyn L, Papoli M, Kinde I, Afsari B, Tregnago AC, Bezerra SM, VandenBussche C, Fujita K, Ertoy D, Cunha IW, Yu L, Bivalacqua TJ, Grollman AP, Diaz LA, Karchin R, Danilova L, Huang CY, Shun CT, Turesky RJ, Yun BH, Rosenquist TA, Pu YS, Hruban RH, Tomasetti C, Papadopoulos N, Kinzler KW, Vogelstein B, Dickman KG, Netto GJ.

Elife. 2018 Nov 12;7. pii: e43237. doi: 10.7554/eLife.43237.

3.

Non-invasive detection of urothelial cancer through the analysis of driver gene mutations and aneuploidy.

Springer SU, Chen CH, Rodriguez Pena MDC, Li L, Douville C, Wang Y, Cohen JD, Taheri D, Silliman N, Schaefer J, Ptak J, Dobbyn L, Papoli M, Kinde I, Afsari B, Tregnago AC, Bezerra SM, VandenBussche C, Fujita K, Ertoy D, Cunha IW, Yu L, Bivalacqua TJ, Grollman AP, Diaz LA, Karchin R, Danilova L, Huang CY, Shun CT, Turesky RJ, Yun BH, Rosenquist TA, Pu YS, Hruban RH, Tomasetti C, Papadopoulos N, Kinzler KW, Vogelstein B, Dickman KG, Netto GJ.

Elife. 2018 Mar 20;7. pii: e32143. doi: 10.7554/eLife.32143. Erratum in: Elife. 2018 Nov 12;7:.

4.

Human liver-kidney model elucidates the mechanisms of aristolochic acid nephrotoxicity.

Chang SY, Weber EJ, Sidorenko VS, Chapron A, Yeung CK, Gao C, Mao Q, Shen D, Wang J, Rosenquist TA, Dickman KG, Neumann T, Grollman AP, Kelly EJ, Himmelfarb J, Eaton DL.

JCI Insight. 2017 Nov 16;2(22). pii: 95978. doi: 10.1172/jci.insight.95978. eCollection 2017 Nov 16.

5.

A Rapid Throughput Method To Extract DNA from Formalin-Fixed Paraffin-Embedded Tissues for Biomonitoring Carcinogenic DNA Adducts.

Yun BH, Xiao S, Yao L, Krishnamachari S, Rosenquist TA, Dickman KG, Grollman AP, Murugan P, Weight CJ, Turesky RJ.

Chem Res Toxicol. 2017 Dec 18;30(12):2130-2139. doi: 10.1021/acs.chemrestox.7b00218. Epub 2017 Nov 27.

6.

Epidemiology, diagnosis, preoperative evaluation and prognostic assessment of upper-tract urothelial carcinoma (UTUC).

Soria F, Shariat SF, Lerner SP, Fritsche HM, Rink M, Kassouf W, Spiess PE, Lotan Y, Ye D, Fernández MI, Kikuchi E, Chade DC, Babjuk M, Grollman AP, Thalmann GN.

World J Urol. 2017 Mar;35(3):379-387. doi: 10.1007/s00345-016-1928-x. Epub 2016 Sep 7. Review.

PMID:
27604375
7.

Aristolochic Acid in the Etiology of Renal Cell Carcinoma.

Hoang ML, Chen CH, Chen PC, Roberts NJ, Dickman KG, Yun BH, Turesky RJ, Pu YS, Vogelstein B, Papadopoulos N, Grollman AP, Kinzler KW, Rosenquist TA.

Cancer Epidemiol Biomarkers Prev. 2016 Dec;25(12):1600-1608. Epub 2016 Aug 23.

8.

Genome-wide quantification of rare somatic mutations in normal human tissues using massively parallel sequencing.

Hoang ML, Kinde I, Tomasetti C, McMahon KW, Rosenquist TA, Grollman AP, Kinzler KW, Vogelstein B, Papadopoulos N.

Proc Natl Acad Sci U S A. 2016 Aug 30;113(35):9846-51. doi: 10.1073/pnas.1607794113. Epub 2016 Aug 15.

9.

Y-family DNA polymerase-independent gap-filling translesion synthesis across aristolochic acid-derived adenine adducts in mouse cells.

Hashimoto K, Bonala R, Johnson F, Grollman AP, Moriya M.

DNA Repair (Amst). 2016 Oct;46:55-60. doi: 10.1016/j.dnarep.2016.07.003. Epub 2016 Jul 29.

10.

Recurrence pattern and TP53 mutation in upper urinary tract urothelial carcinoma.

Chen CH, Dickman KG, Huang CY, Shun CT, Tai HC, Huang KH, Wang SM, Lee YJ, Grollman AP, Pu YS.

Oncotarget. 2016 Jul 19;7(29):45225-45236. doi: 10.18632/oncotarget.9904.

11.

Mutational signature of aristolochic acid: Clue to the recognition of a global disease.

Rosenquist TA, Grollman AP.

DNA Repair (Amst). 2016 Aug;44:205-211. doi: 10.1016/j.dnarep.2016.05.027. Epub 2016 May 20. Review.

PMID:
27237586
12.

Sulfotransferase-1A1-dependent bioactivation of aristolochic acid I and N-hydroxyaristolactam I in human cells.

Hashimoto K, Zaitseva IN, Bonala R, Attaluri S, Ozga K, Iden CR, Johnson F, Moriya M, Grollman AP, Sidorenko VS.

Carcinogenesis. 2016 Jul;37(7):647-655. doi: 10.1093/carcin/bgw045. Epub 2016 Apr 18.

13.

The non-homologous end-joining pathway of S. cerevisiae works effectively in G1-phase cells, and religates cognate ends correctly and non-randomly.

Gao S, Honey S, Futcher B, Grollman AP.

DNA Repair (Amst). 2016 Jun;42:1-10. doi: 10.1016/j.dnarep.2016.03.013. Epub 2016 Apr 14.

14.
15.

Multiclass Carcinogenic DNA Adduct Quantification in Formalin-Fixed Paraffin-Embedded Tissues by Ultraperformance Liquid Chromatography-Tandem Mass Spectrometry.

Guo J, Yun BH, Upadhyaya P, Yao L, Krishnamachari S, Rosenquist TA, Grollman AP, Turesky RJ.

Anal Chem. 2016 May 3;88(9):4780-7. doi: 10.1021/acs.analchem.6b00124. Epub 2016 Apr 15.

16.

Toxicity of Botanical Medicines: An Overlooked Global Health Problem.

Marcus DM, Grollman AP.

Am J Public Health. 2016 Jan;106(1):16-7. doi: 10.2105/AJPH.2015.302937. Epub 2015 Nov 12. No abstract available.

17.

Low-Coverage Exome Sequencing Screen in Formalin-Fixed Paraffin-Embedded Tumors Reveals Evidence of Exposure to Carcinogenic Aristolochic Acid.

Castells X, Karanović S, Ardin M, Tomić K, Xylinas E, Durand G, Villar S, Forey N, Le Calvez-Kelm F, Voegele C, Karlović K, Mišić M, Dittrich D, Dolgalev I, McKay J, Shariat SF, Sidorenko VS, Fernandes A, Heguy A, Dickman KG, Olivier M, Grollman AP, Jelaković B, Zavadil J.

Cancer Epidemiol Biomarkers Prev. 2015 Dec;24(12):1873-81. doi: 10.1158/1055-9965.EPI-15-0553. Epub 2015 Sep 17.

18.

New Approaches for Biomonitoring Exposure to the Human Carcinogen Aristolochic Acid.

Yun BH, Sidorenko VS, Rosenquist TA, Dickman KG, Grollman AP, Turesky RJ.

Toxicol Res (Camb). 2015 Jul 1;4(4):763-776.

19.

Impact of thymine glycol damage on DNA duplex energetics: Correlations with lesion-induced biochemical and structural consequences.

Minetti CA, Remeta DP, Iden CR, Johnson F, Grollman AP, Breslauer KJ.

Biopolymers. 2015 Sep;103(9):491-508. doi: 10.1002/bip.22680.

PMID:
25991500
20.

Chronic dietary exposure to aristolochic acid and kidney function in native farmers from a Croatian endemic area and Bosnian immigrants.

Jelaković B, Vuković Lela I, Karanović S, Dika Ž, Kos J, Dickman K, Šekoranja M, Poljičanin T, Mišić M, Premužić V, Abramović M, Matijević V, Miletić Medved M, Cvitković A, Edwards K, Fuček M, Leko N, Teskera T, Laganović M, Čvorišćec D, Grollman AP.

Clin J Am Soc Nephrol. 2015 Feb 6;10(2):215-23. doi: 10.2215/CJN.03190314. Epub 2015 Jan 13.

21.

Active destabilization of base pairs by a DNA glycosylase wedge initiates damage recognition.

Kuznetsov NA, Bergonzo C, Campbell AJ, Li H, Mechetin GV, de los Santos C, Grollman AP, Fedorova OS, Zharkov DO, Simmerling C.

Nucleic Acids Res. 2015 Jan;43(1):272-81. doi: 10.1093/nar/gku1300. Epub 2014 Dec 17.

22.

Aristolochic acid-induced apoptosis and G2 cell cycle arrest depends on ROS generation and MAP kinases activation.

Romanov V, Whyard TC, Waltzer WC, Grollman AP, Rosenquist T.

Arch Toxicol. 2015 Jan;89(1):47-56. doi: 10.1007/s00204-014-1249-z. Epub 2014 May 4.

PMID:
24792323
23.

Formalin-fixed paraffin-embedded tissue as a source for quantitation of carcinogen DNA adducts: aristolochic acid as a prototype carcinogen.

Yun BH, Yao L, Jelaković B, Nikolić J, Dickman KG, Grollman AP, Rosenquist TA, Turesky RJ.

Carcinogenesis. 2014 Sep;35(9):2055-61. doi: 10.1093/carcin/bgu101. Epub 2014 Apr 28.

24.

Bioactivation of the human carcinogen aristolochic acid.

Sidorenko VS, Attaluri S, Zaitseva I, Iden CR, Dickman KG, Johnson F, Grollman AP.

Carcinogenesis. 2014 Aug;35(8):1814-22. doi: 10.1093/carcin/bgu095. Epub 2014 Apr 17.

25.

Is herbal tea consumption a factor in endemic nephropathy?

Ivković V, Karanović S, Fištrek Prlić M, Mišić M, Kos J, Jurić D, Vuković Lela I, Vitale K, Cvitković A, Laganović M, Fodor L, Edwards K, Grollman AP, Jelaković B.

Eur J Epidemiol. 2014 Mar;29(3):221-4. doi: 10.1007/s10654-014-9886-3. Epub 2014 Mar 13. No abstract available.

PMID:
24623403
26.

Highlights from the first symposium on upper tract urothelial carcinoma.

Matin SF, Shariat SF, Milowsky MI, Hansel DE, Kassouf W, Koppie T, Bajorin D, Grollman AP.

Urol Oncol. 2014 Apr;32(3):309-16. doi: 10.1016/j.urolonc.2013.08.029. Epub 2014 Jan 4. Review.

PMID:
24397995
27.

Consensus statement on screening, diagnosis, classification and treatment of endemic (Balkan) nephropathy.

Jelaković B, Nikolić J, Radovanović Z, Nortier J, Cosyns JP, Grollman AP, Bašić-Jukić N, Belicza M, Bukvić D, Čavaljuga S, Čvorišćec D, Cvitković A, Dika Ž, Dimitrov P, Đukanović L, Edwards K, Ferluga D, Fuštar-Preradović L, Gluhovschi G, Imamović G, Jakovina T, Kes P, Leko N, Medverec Z, Mesić E, Miletić-Medved M, Miller F, Pavlović N, Pasini J, Pleština S, Polenaković M, Stefanović V, Tomić K, Trnačević S, Vuković Lela I, Štern-Padovan R.

Nephrol Dial Transplant. 2014 Nov;29(11):2020-7. doi: 10.1093/ndt/gft384. Epub 2013 Oct 28. Review.

28.

Mutational signature of aristolochic acid exposure as revealed by whole-exome sequencing.

Hoang ML, Chen CH, Sidorenko VS, He J, Dickman KG, Yun BH, Moriya M, Niknafs N, Douville C, Karchin R, Turesky RJ, Pu YS, Vogelstein B, Papadopoulos N, Grollman AP, Kinzler KW, Rosenquist TA.

Sci Transl Med. 2013 Aug 7;5(197):197ra102. doi: 10.1126/scitranslmed.3006200.

29.

Human formalin-fixed paraffin-embedded tissues: an untapped specimen for biomonitoring of carcinogen DNA adducts by mass spectrometry.

Yun BH, Rosenquist TA, Nikolić J, Dragičević D, Tomić K, Jelaković B, Dickman KG, Grollman AP, Turesky RJ.

Anal Chem. 2013 May 7;85(9):4251-8. doi: 10.1021/ac400612x. Epub 2013 Apr 10.

30.

TERT promoter mutations occur frequently in gliomas and a subset of tumors derived from cells with low rates of self-renewal.

Killela PJ, Reitman ZJ, Jiao Y, Bettegowda C, Agrawal N, Diaz LA Jr, Friedman AH, Friedman H, Gallia GL, Giovanella BC, Grollman AP, He TC, He Y, Hruban RH, Jallo GI, Mandahl N, Meeker AK, Mertens F, Netto GJ, Rasheed BA, Riggins GJ, Rosenquist TA, Schiffman M, Shih IeM, Theodorescu D, Torbenson MS, Velculescu VE, Wang TL, Wentzensen N, Wood LD, Zhang M, McLendon RE, Bigner DD, Kinzler KW, Vogelstein B, Papadopoulos N, Yan H.

Proc Natl Acad Sci U S A. 2013 Apr 9;110(15):6021-6. doi: 10.1073/pnas.1303607110. Epub 2013 Mar 25.

31.

Analysis of TP53 mutation spectra reveals the fingerprint of the potent environmental carcinogen, aristolochic acid.

Hollstein M, Moriya M, Grollman AP, Olivier M.

Mutat Res. 2013 Jul-Sep;753(1):41-9. doi: 10.1016/j.mrrev.2013.02.003. Epub 2013 Feb 17. Review.

32.

Correcting the record on dietary supplement regulation--reply.

Marcus DM, Grollman AP.

JAMA Intern Med. 2013 Jan 28;173(2):166-7. doi: 10.1001/jamainternmed.2013.1747. No abstract available.

PMID:
23358839
33.

Aristolochic acid-induced upper tract urothelial carcinoma in Taiwan: clinical characteristics and outcomes.

Chen CH, Dickman KG, Huang CY, Moriya M, Shun CT, Tai HC, Huang KH, Wang SM, Lee YJ, Grollman AP, Pu YS.

Int J Cancer. 2013 Jul;133(1):14-20. doi: 10.1002/ijc.28013. Epub 2013 Feb 12.

34.

Aristolochic acid nephropathy: Harbinger of a global iatrogenic disease.

Grollman AP.

Environ Mol Mutagen. 2013 Jan;54(1):1-7. doi: 10.1002/em.21756. Epub 2012 Dec 13. Review.

PMID:
23238808
35.

The consequences of ineffective regulation of dietary supplements.

Marcus DM, Grollman AP.

Arch Intern Med. 2012 Jul 9;172(13):1035-6. doi: 10.1001/archinternmed.2012.2687. No abstract available.

PMID:
22777632
36.

Biomonitoring of aristolactam-DNA adducts in human tissues using ultra-performance liquid chromatography/ion-trap mass spectrometry.

Yun BH, Rosenquist TA, Sidorenko V, Iden CR, Chen CH, Pu YS, Bonala R, Johnson F, Dickman KG, Grollman AP, Turesky RJ.

Chem Res Toxicol. 2012 May 21;25(5):1119-31. doi: 10.1021/tx3000889. Epub 2012 May 4.

37.

Aristolochic acid-associated urothelial cancer in Taiwan.

Chen CH, Dickman KG, Moriya M, Zavadil J, Sidorenko VS, Edwards KL, Gnatenko DV, Wu L, Turesky RJ, Wu XR, Pu YS, Grollman AP.

Proc Natl Acad Sci U S A. 2012 May 22;109(21):8241-6. doi: 10.1073/pnas.1119920109. Epub 2012 Apr 9.

38.

A fluorescence-based analysis of aristolochic acid-derived DNA adducts.

Romanov V, Sidorenko V, Rosenquist TA, Whyard T, Grollman AP.

Anal Biochem. 2012 Aug 1;427(1):49-51. doi: 10.1016/j.ab.2012.03.027. Epub 2012 Apr 4.

39.

Lack of recognition by global-genome nucleotide excision repair accounts for the high mutagenicity and persistence of aristolactam-DNA adducts.

Sidorenko VS, Yeo JE, Bonala RR, Johnson F, Schärer OD, Grollman AP.

Nucleic Acids Res. 2012 Mar;40(6):2494-505. doi: 10.1093/nar/gkr1095. Epub 2011 Nov 25.

40.

Aristolactam-DNA adducts are a biomarker of environmental exposure to aristolochic acid.

Jelaković B, Karanović S, Vuković-Lela I, Miller F, Edwards KL, Nikolić J, Tomić K, Slade N, Brdar B, Turesky RJ, Stipančić Ž, Dittrich D, Grollman AP, Dickman KG.

Kidney Int. 2012 Mar;81(6):559-67. doi: 10.1038/ki.2011.371. Epub 2011 Nov 9.

41.

Energetic preference of 8-oxoG eversion pathways in a DNA glycosylase.

Bergonzo C, Campbell AJ, de los Santos C, Grollman AP, Simmerling C.

J Am Chem Soc. 2011 Sep 21;133(37):14504-6. doi: 10.1021/ja205142d. Epub 2011 Aug 25.

42.

TP53 Mutational signature for aristolochic acid: an environmental carcinogen.

Moriya M, Slade N, Brdar B, Medverec Z, Tomic K, Jelaković B, Wu L, Truong S, Fernandes A, Grollman AP.

Int J Cancer. 2011 Sep 15;129(6):1532-6. doi: 10.1002/ijc.26077. Epub 2011 Jun 9.

43.

Cytochrome P450 1A2 detoxicates aristolochic acid in the mouse.

Rosenquist TA, Einolf HJ, Dickman KG, Wang L, Smith A, Grollman AP.

Drug Metab Dispos. 2010 May;38(5):761-8. doi: 10.1124/dmd.110.032201. Epub 2010 Feb 17.

44.

Detoxification of aristolochic acid I by O-demethylation: less nephrotoxicity and genotoxicity of aristolochic acid Ia in rodents.

Shibutani S, Bonala RR, Rosenquist T, Rieger R, Suzuki N, Johnson F, Miller F, Grollman AP.

Int J Cancer. 2010 Sep 1;127(5):1021-7. doi: 10.1002/ijc.25141.

45.

An Improved Reaction Coordinate for Nucleic Acid Base Flipping Studies.

Song K, Campbell AJ, Bergonzo C, de Los Santos C, Grollman AP, Simmerling C.

J Chem Theory Comput. 2009 Nov 10;5(11):3105-13. doi: 10.1021/ct9001575. Epub 2009 Oct 9.

46.

DNA adducts of aristolochic acid II: total synthesis and site-specific mutagenesis studies in mammalian cells.

Attaluri S, Bonala RR, Yang IY, Lukin MA, Wen Y, Grollman AP, Moriya M, Iden CR, Johnson F.

Nucleic Acids Res. 2010 Jan;38(1):339-52. doi: 10.1093/nar/gkp815. Epub 2009 Oct 23.

47.

Substrate specificity and excision kinetics of natural polymorphic variants and phosphomimetic mutants of human 8-oxoguanine-DNA glycosylase.

Sidorenko VS, Grollman AP, Jaruga P, Dizdaroglu M, Zharkov DO.

FEBS J. 2009 Sep;276(18):5149-62. doi: 10.1111/j.1742-4658.2009.07212.x. Epub 2009 Aug 7.

48.

Transplantation for Chinese herb nephropathy.

Morrissey PE, Gautam A, Yang A, Grollman AP, Esparza A, Gohh RY, Monaco AP.

Clin Transpl. 2006:560. No abstract available.

PMID:
18365433
49.

Molecular simulations reveal a common binding mode for glycosylase binding of oxidatively damaged DNA lesions.

Song K, Kelso C, de los Santos C, Grollman AP, Simmerling C.

J Am Chem Soc. 2007 Nov 28;129(47):14536-7. Epub 2007 Nov 8.

50.

Limitations of "evidence-based indications" for herbs.

Marcus DM, Grollman AP.

Mayo Clin Proc. 2007 Nov;82(11):1433; author reply 1433-4. No abstract available.

PMID:
17976363

Supplemental Content

Loading ...
Support Center