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Items: 1 to 50 of 187


The effect of computerized decision support systems on cardiovascular risk factors: a systematic review and meta-analysis.

Groenhof TKJ, Asselbergs FW, Groenwold RHH, Grobbee DE, Visseren FLJ, Bots ML; UCC-SMART study group.

BMC Med Inform Decis Mak. 2019 Jun 10;19(1):108. doi: 10.1186/s12911-019-0824-x.


Impact of predictor measurement heterogeneity across settings on the performance of prediction models: A measurement error perspective.

Luijken K, Groenwold RHH, Van Calster B, Steyerberg EW, van Smeden M.

Stat Med. 2019 May 31. doi: 10.1002/sim.8183. [Epub ahead of print]


The Trials within Cohorts (TwiCs) design faced methodological advantages and disadvantages in the exercise-oncology setting.

Gal R, Monninkhof EM, van Gils CH, Groenwold RHH, van den Bongard DHJG, Peeters PHM, Verkooijen HM, May AM.

J Clin Epidemiol. 2019 May 27. pii: S0895-4356(19)30021-6. doi: 10.1016/j.jclinepi.2019.05.017. [Epub ahead of print]


When and how to use data from randomised trials to develop or validate prognostic models.

Pajouheshnia R, Groenwold RHH, Peelen LM, Reitsma JB, Moons KGM.

BMJ. 2019 May 29;365:l2154. doi: 10.1136/bmj.l2154. No abstract available.


Adjusting for Disease Severity Across ICUs in Multicenter Studies.

Brakenhoff TB, Plantinga NL, Wittekamp BHJ, Cremer O, de Lange DW, de Keizer NF, Bakhshi-Raiez F, Groenwold RHH, Peelen LM.

Crit Care Med. 2019 May 24. doi: 10.1097/CCM.0000000000003822. [Epub ahead of print]


Mediation analysis of the relationship between type 2 diabetes and cardiovascular events and all-cause mortality: Findings from the SMART cohort.

Sharif S, Groenwold RHH, van der Graaf Y, Berkelmans GFN, Cramer MJ, Visseren FLJ, Westerink J; SMART study group.

Diabetes Obes Metab. 2019 May 7. doi: 10.1111/dom.13759. [Epub ahead of print]


Association of menopausal characteristics and risk of coronary heart disease: a pan-European case-cohort analysis.

Dam V, van der Schouw YT, Onland-Moret NC, Groenwold RHH, Peters SAE, Burgess S, Wood AM, Chirlaque MD, Moons KGM, Oliver-Williams C, Schuit E, Tikk K, Weiderpass E, Holm M, Tjønneland A, Kühn T, Fortner RT, Trichopoulou A, Karakatsani A, La Vecchia C, Ferrari P, Gunter M, Masala G, Sieri S, Tumino R, Panico S, Boer JMA, Verschuren WMM, Salamanca-Fernández E, Arriola L, Moreno-Iribas C, Engström G, Melander O, Nordendahl M, Wennberg P, Key TJ, Colorado-Yohar S, Matullo G, Overvad K, Clavel-Chapelon F, Boeing H, Quiros JR, di Angelantonio E, Langenberg C, Sweeting MJ, Riboli E, Wareham NJ, Danesh J, Butterworth A.

Int J Epidemiol. 2019 Feb 22. pii: dyz016. doi: 10.1093/ije/dyz016. [Epub ahead of print]


Quality of reporting of systematic reviews and meta-analyses in emergency medicine based on the PRISMA statement.

Nawijn F, Ham WHW, Houwert RM, Groenwold RHH, Hietbrink F, Smeeing DPJ.

BMC Emerg Med. 2019 Feb 11;19(1):19. doi: 10.1186/s12873-019-0233-6.


Risk factors for incident heart failure in age- and sex-specific strata: a population-based cohort using linked electronic health records.

Uijl A, Koudstaal S, Direk K, Denaxas S, Groenwold RHH, Banerjee A, Hoes AW, Hemingway H, Asselbergs FW.

Eur J Heart Fail. 2019 Jan 7. doi: 10.1002/ejhf.1350. [Epub ahead of print]


Operative treatment versus nonoperative treatment of Achilles tendon ruptures: systematic review and meta-analysis.

Ochen Y, Beks RB, van Heijl M, Hietbrink F, Leenen LPH, van der Velde D, Heng M, van der Meijden O, Groenwold RHH, Houwert RM.

BMJ. 2019 Jan 7;364:k5120. doi: 10.1136/bmj.k5120.


Adjustment for unmeasured confounding through informative priors for the confounder-outcome relation.

Groenwold RHH, Shofty I, Miočević M, van Smeden M, Klugkist I.

BMC Med Res Methodol. 2018 Dec 22;18(1):174. doi: 10.1186/s12874-018-0634-3.


[Big, bigger, biggest; big data in medical research].

Groenwold RHH, Nab L, van Smeden M.

Ned Tijdschr Geneeskd. 2018 Nov 27;162. pii: D3108. Dutch.


Systematic review showed that stepped-wedge cluster randomized trials often did not reach their planned sample size.

Eichner FA, Groenwold RHH, Grobbee DE, Oude Rengerink K.

J Clin Epidemiol. 2019 Mar;107:89-100. doi: 10.1016/j.jclinepi.2018.11.013. Epub 2018 Nov 17.


Rib fixation versus non-operative treatment for flail chest and multiple rib fractures after blunt thoracic trauma: a multicenter cohort study.

Beks RB, Reetz D, de Jong MB, Groenwold RHH, Hietbrink F, Edwards MJR, Leenen LPH, Houwert RM, Frölke JPM.

Eur J Trauma Emerg Surg. 2018 Oct 19. doi: 10.1007/s00068-018-1037-1. [Epub ahead of print]


Fixation of flail chest or multiple rib fractures: current evidence and how to proceed. A systematic review and meta-analysis.

Beks RB, Peek J, de Jong MB, Wessem KJP, Öner CF, Hietbrink F, Leenen LPH, Groenwold RHH, Houwert RM.

Eur J Trauma Emerg Surg. 2018 Oct 1. doi: 10.1007/s00068-018-1020-x. [Epub ahead of print] Review.


Weight-bearing or non-weight-bearing after surgical treatment of ankle fractures: a multicenter randomized controlled trial.

Smeeing DPJ, Houwert RM, Briet JP, Groenwold RHH, Lansink KWW, Leenen LPH, van der Zwaal P, Hoogendoorn JM, van Heijl M, Verleisdonk EJ, Segers MJM, Hietbrink F.

Eur J Trauma Emerg Surg. 2018 Sep 24. doi: 10.1007/s00068-018-1016-6. [Epub ahead of print]


Long-term follow-up after rib fixation for flail chest and multiple rib fractures.

Beks RB, de Jong MB, Houwert RM, Sweet AAR, De Bruin IGJM, Govaert GAM, Wessem KJP, Simmermacher RKJ, Hietbrink F, Groenwold RHH, Leenen LPH.

Eur J Trauma Emerg Surg. 2018 Sep 18. doi: 10.1007/s00068-018-1009-5. [Epub ahead of print]


How variation in predictor measurement affects the discriminative ability and transportability of a prediction model.

Pajouheshnia R, van Smeden M, Peelen LM, Groenwold RHH.

J Clin Epidemiol. 2019 Jan;105:136-141. doi: 10.1016/j.jclinepi.2018.09.001. Epub 2018 Sep 14.


Merits and caveats of propensity scores to adjust for confounding.

Fu EL, Groenwold RHH, Zoccali C, Jager KJ, van Diepen M, Dekker FW.

Nephrol Dial Transplant. 2018 Sep 11. doi: 10.1093/ndt/gfy283. [Epub ahead of print]


Comparability of treatment arms does not prevent correlated trial results.

Groenwold RHH, van Smeden M.

J Clin Epidemiol. 2019 Feb;106:144-145. doi: 10.1016/j.jclinepi.2018.08.011. Epub 2018 Aug 24. No abstract available.


Investigating Risk Adjustment Methods for Health Care Provider Profiling When Observations are Scarce or Events Rare.

Brakenhoff TB, Moons KG, Kluin J, Groenwold RH.

Health Serv Insights. 2018 Jul 5;11:1178632918785133. doi: 10.1177/1178632918785133. eCollection 2018.


Prediction models for clustered data with informative priors for the random effects: a simulation study.

Ni H, Groenwold RHH, Nielen M, Klugkist I.

BMC Med Res Methodol. 2018 Aug 6;18(1):83. doi: 10.1186/s12874-018-0543-5.


Using a single noninferiority margin or preserved fraction for an entire pharmacological class was found to be inappropriate.

Althunian TA, de Boer A, Groenwold RHH, Klungel OH.

J Clin Epidemiol. 2018 Dec;104:15-23. doi: 10.1016/j.jclinepi.2018.07.004. Epub 2018 Aug 25.


Outlier classification performance of risk adjustment methods when profiling multiple providers.

Brakenhoff TB, Roes KCB, Moons KGM, Groenwold RHH.

BMC Med Res Methodol. 2018 Jun 15;18(1):54. doi: 10.1186/s12874-018-0510-1.


Operative versus nonoperative treatment of proximal humeral fractures: a systematic review, meta-analysis, and comparison of observational studies and randomized controlled trials.

Beks RB, Ochen Y, Frima H, Smeeing DPJ, van der Meijden O, Timmers TK, van der Velde D, van Heijl M, Leenen LPH, Groenwold RHH, Houwert RM.

J Shoulder Elbow Surg. 2018 Aug;27(8):1526-1534. doi: 10.1016/j.jse.2018.03.009. Epub 2018 May 4. Review.


Machine Learning Compared With Pathologist Assessment.

van Smeden M, Van Calster B, Groenwold RHH.

JAMA. 2018 Apr 24;319(16):1725-1726. doi: 10.1001/jama.2018.1466. No abstract available.


Investigation of the "m" in the cmRCT (cohort multiple randomized controlled trial) design revealed dependence between trial results.

Groenwold RHH, van Smeden M.

J Clin Epidemiol. 2018 Sep;101:119-123. doi: 10.1016/j.jclinepi.2018.04.019. Epub 2018 Apr 26. No abstract available.


[Power, you can never have enough of it].

Groenwold RHH, van Smeden M, Dekkers OM.

Ned Tijdschr Geneeskd. 2018;162:D2163. Dutch.


Measurement error is often neglected in medical literature: a systematic review.

Brakenhoff TB, Mitroiu M, Keogh RH, Moons KGM, Groenwold RHH, van Smeden M.

J Clin Epidemiol. 2018 Jun;98:89-97. doi: 10.1016/j.jclinepi.2018.02.023. Epub 2018 Mar 6. Review.


Random measurement error: Why worry? An example of cardiovascular risk factors.

Brakenhoff TB, van Smeden M, Visseren FLJ, Groenwold RHH.

PLoS One. 2018 Feb 9;13(2):e0192298. doi: 10.1371/journal.pone.0192298. eCollection 2018.


[Significance of p-values: misinterpreted and overrated].

Dekkers OM, Groenwold RHH.

Ned Tijdschr Geneeskd. 2018;162:D2161. Dutch.


Fair inclusion of pregnant women in clinical trials: an integrated scientific and ethical approach.

van der Graaf R, van der Zande ISE, den Ruijter HM, Oudijk MA, van Delden JJM, Oude Rengerink K, Groenwold RHH.

Trials. 2018 Jan 29;19(1):78. doi: 10.1186/s13063-017-2402-9.


The effects of misclassification in routine healthcare databases on the accuracy of prognostic prediction models: a case study of the CHA2DS2-VASc score in atrial fibrillation.

van Doorn S, Brakenhoff TB, Moons KGM, Rutten FH, Hoes AW, Groenwold RHH, Geersing GJ.

Diagn Progn Res. 2017 Nov 16;1:18. doi: 10.1186/s41512-017-0018-x. eCollection 2017.


The effects of exercise on the quality of life of patients with breast cancer (the UMBRELLA Fit study): study protocol for a randomized controlled trial.

Gal R, Monninkhof EM, Groenwold RHH, van Gils CH, van den Bongard DHJG, Peeters PHM, Verkooijen HM, May AM.

Trials. 2017 Oct 27;18(1):504. doi: 10.1186/s13063-017-2252-5.


Cautionary note: propensity score matching does not account for bias due to censoring.

Penning de Vries BBL, Groenwold RHH.

Nephrol Dial Transplant. 2018 Jun 1;33(6):914-916. doi: 10.1093/ndt/gfx198.


Treatment use in prognostic model research: a systematic review of cardiovascular prognostic studies.

Pajouheshnia R, Damen JAAG, Groenwold RHH, Moons KGM, Peelen LM.

Diagn Progn Res. 2017 Sep 26;1:15. doi: 10.1186/s41512-017-0015-0. eCollection 2017. Review.


Atmospheric Pressure and Abdominal Aortic Aneurysm Rupture: Results From a Time Series Analysis and Case-Crossover Study.

Penning de Vries BBL, Kolkert JLP, Meerwaldt R, Groenwold RHH.

Vasc Endovascular Surg. 2017 Oct;51(7):441-446. doi: 10.1177/1538574417713909. Epub 2017 Jul 25.


Accounting for treatment use when validating a prognostic model: a simulation study.

Pajouheshnia R, Peelen LM, Moons KGM, Reitsma JB, Groenwold RHH.

BMC Med Res Methodol. 2017 Jul 14;17(1):103. doi: 10.1186/s12874-017-0375-8.


Efficient Sampling in Unmatched Case-Control Studies When the Total Number of Cases and Controls Is Fixed.

Groenwold RHH, van Smeden M.

Epidemiology. 2017 Nov;28(6):834-837. doi: 10.1097/EDE.0000000000000710.


Designing pragmatic trials-what can we learn from lessons learned?

Groenwold RHH, Dekkers OM.

J Clin Epidemiol. 2017 Oct;90:3-5. doi: 10.1016/j.jclinepi.2017.06.006. Epub 2017 Jun 16.


Cost-Effectiveness of Two Decision Strategies for Shunt Use During Carotid Endarterectomy.

Kolkert JLP, Groenwold RHH, Leijdekkers VJ, Ter Haar J, Zeebregts CJ, Vahl A.

World J Surg. 2017 Nov;41(11):2959-2967. doi: 10.1007/s00268-017-4085-5.


Series: Pragmatic trials and real world evidence: Paper 1. Introduction.

Zuidgeest MGP, Goetz I, Groenwold RHH, Irving E, van Thiel GJMW, Grobbee DE; GetReal Work Package 3.

J Clin Epidemiol. 2017 Aug;88:7-13. doi: 10.1016/j.jclinepi.2016.12.023. Epub 2017 May 24.


Series: Pragmatic trials and real world evidence: Paper 2. Setting, sites, and investigator selection.

Worsley SD, Oude Rengerink K, Irving E, Lejeune S, Mol K, Collier S, Groenwold RHH, Enters-Weijnen C, Egger M, Rhodes T; GetReal Work Package 3.

J Clin Epidemiol. 2017 Aug;88:14-20. doi: 10.1016/j.jclinepi.2017.05.003. Epub 2017 May 11. Review.


Series: Pragmatic trials and real world evidence: Paper 3. Patient selection challenges and consequences.

Oude Rengerink K, Kalkman S, Collier S, Ciaglia A, Worsley SD, Lightbourne A, Eckert L, Groenwold RHH, Grobbee DE, Irving EA; Work Package 3 of the GetReal consortium.

J Clin Epidemiol. 2017 Sep;89:173-180. doi: 10.1016/j.jclinepi.2016.12.021. Epub 2017 May 11.


[Added value of observational studies in surgery: the hierarchical structure of study designs requires a more refined approach].

Beks RB, Houwert RM, Groenwold RHH.

Ned Tijdschr Geneeskd. 2017;161:D1493. Dutch.


The importance of considering competing treatment affecting prognosis in the evaluation of therapy in trials: the example of renal transplantation in hemodialysis trials.

Hazelbag CM, Peters SAE, Blankestijn PJ, Bots ML, Canaud B, Davenport A, Grooteman MPC, Kircelli F, Locatelli F, Maduell F, Morena M, Nubé MJ, Ok E, Torres F, Hoes AW, Groenwold RHH; HDF Pooling Project investigators.

Nephrol Dial Transplant. 2017 Apr 1;32(suppl_2):ii31-ii39. doi: 10.1093/ndt/gfw458.


Methods of defining the non-inferiority margin in randomized, double-blind controlled trials: a systematic review.

Althunian TA, de Boer A, Klungel OH, Insani WN, Groenwold RH.

Trials. 2017 Mar 7;18(1):107. doi: 10.1186/s13063-017-1859-x. Review.


Defining the noninferiority margin and analysing noninferiority: An overview.

Althunian TA, de Boer A, Groenwold RHH, Klungel OH.

Br J Clin Pharmacol. 2017 Aug;83(8):1636-1642. doi: 10.1111/bcp.13280. Epub 2017 Apr 6.


A systematic literature review on the efficacy-effectiveness gap: comparison of randomized controlled trials and observational studies of glucose-lowering drugs.

Ankarfeldt MZ, Adalsteinsson E, Groenwold RH, Ali MS, Klungel OH.

Clin Epidemiol. 2017 Jan 23;9:41-51. doi: 10.2147/CLEP.S121991. eCollection 2017. Review.


Assessment of channeling bias among initiators of glucose-lowering drugs: A UK cohort study.

Ankarfeldt MZ, Thorsted BL, Groenwold RH, Adalsteinsson E, Ali MS, Klungel OH.

Clin Epidemiol. 2017 Jan 18;9:19-30. doi: 10.2147/CLEP.S124054. eCollection 2017. Erratum in: Clin Epidemiol. 2018 Nov 28;10:1787.

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