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Items: 1 to 50 of 224

1.

Hospital-level evaluation of the effect of a national quality improvement programme: time-series analysis of registry data.

Stephens TJ, Peden CJ, Haines R, Grocott MPW, Murray D, Cromwell D, Johnston C, Hare S, Lourtie J, Drake S, Martin GP, Pearse RM; Enhanced Perioperative Care for High-risk patients (EPOCH) trial group.

BMJ Qual Saf. 2019 Sep 12. pii: bmjqs-2019-009537. doi: 10.1136/bmjqs-2019-009537. [Epub ahead of print]

PMID:
31515437
2.

Immunonutrition for Adults With ARDS: Results From a Cochrane Systematic Review and Meta-Analysis.

Dushianthan A, Cusack R, Burgess VA, Grocott MP, Calder P.

Respir Care. 2019 Sep 10. pii: respcare.06965. doi: 10.4187/respcare.06965. [Epub ahead of print] Review.

PMID:
31506339
3.

Insight into erythrocyte phospholipid molecular flux in healthy humans and in patients with acute respiratory distress syndrome.

Dushianthan A, Cusack R, Koster G, Grocott MPW, Postle AD.

PLoS One. 2019 Aug 27;14(8):e0221595. doi: 10.1371/journal.pone.0221595. eCollection 2019.

4.

Data integrity issues: catalyst for a more robust approach to research on perioperative oxygen therapy?

Oldman AH, Cumpstey AF, Martin DS, Grocott MPW.

Perioper Med (Lond). 2019 Jul 4;8:7. doi: 10.1186/s13741-019-0118-y. eCollection 2019. No abstract available.

5.

Systematic review and consensus definitions for the Standardised Endpoints in Perioperative Medicine initiative: clinical indicators.

Haller G, Bampoe S, Cook T, Fleisher LA, Grocott MPW, Neuman M, Story D, Myles PS; StEP-COMPAC Group.

Br J Anaesth. 2019 Aug;123(2):228-237. doi: 10.1016/j.bja.2019.04.041. Epub 2019 May 23.

6.

Myosteatosis is associated with poor physical fitness in patients undergoing hepatopancreatobiliary surgery.

West MA, van Dijk DPJ, Gleadowe F, Reeves T, Primrose JN, Abu Hilal M, Edwards MR, Jack S, Rensen SSS, Grocott MPW, Levett DZH, Olde Damink SWM.

J Cachexia Sarcopenia Muscle. 2019 Aug;10(4):860-871. doi: 10.1002/jcsm.12433. Epub 2019 May 21.

7.

Preoperative chronic beta-blocker prescription in elderly patients as a risk factor for postoperative mortality stratified by preoperative blood pressure: a cohort study.

Venkatesan S, Jørgensen ME, Manning HJ, Andersson C, Mozid AM, Coburn M, Moonesinghe SR, Foex P, Mythen M, Grocott MPW, Hardman JG, Myles PR, Sanders RD.

Br J Anaesth. 2019 Aug;123(2):118-125. doi: 10.1016/j.bja.2019.03.042. Epub 2019 May 14.

8.

American Society for Enhanced Recovery and Perioperative Quality Initiative Joint Consensus Statement on Perioperative Opioid Minimization in Opioid-Naïve Patients.

Wu CL, King AB, Geiger TM, Grant MC, Grocott MPW, Gupta R, Hah JM, Miller TE, Shaw AD, Gan TJ, Thacker JKM, Mythen MG, McEvoy MD; Fourth Perioperative Quality Initiative Workgroup.

Anesth Analg. 2019 Aug;129(2):567-577. doi: 10.1213/ANE.0000000000004194.

PMID:
31082966
9.

Perioperative oxygen therapy: meaningful outcomes and unintended consequences?

Grocott MPW, Miller TE, Mythen MMG, Martin DS.

Br J Anaesth. 2019 Jul;123(1):e6-e7. doi: 10.1016/j.bja.2019.03.035. Epub 2019 Apr 24. No abstract available.

PMID:
31029408
10.

Chronotropic incompetence and myocardial injury after noncardiac surgery: planned secondary analysis of a prospective observational international cohort study.

Abbott TEF, Pearse RM, Beattie WS, Phull M, Beilstein C, Raj A, Grocott MPW, Cuthbertson BH, Wijeysundera D, Ackland GL.

Br J Anaesth. 2019 Jul;123(1):17-26. doi: 10.1016/j.bja.2019.03.022. Epub 2019 Apr 24.

11.

Perioperative Quality Initiative consensus statement on postoperative blood pressure, risk and outcomes for elective surgery.

McEvoy MD, Gupta R, Koepke EJ, Feldheiser A, Michard F, Levett D, Thacker JKM, Hamilton M, Grocott MPW, Mythen MG, Miller TE, Edwards MR; POQI-3 workgroup; POQI chairs, Miller TE, Mythen MG, Grocott MP, Edwards MR; Physiology group; Preoperative blood pressure group; Intraoperative blood pressure group; Postoperative blood pressure group.

Br J Anaesth. 2019 May;122(5):575-586. doi: 10.1016/j.bja.2019.01.019. Epub 2019 Mar 2.

PMID:
30916008
12.

Perioperative Quality Initiative consensus statement on preoperative blood pressure, risk and outcomes for elective surgery.

Sanders RD, Hughes F, Shaw A, Thompson A, Bader A, Hoeft A, Williams DA, Grocott MPW, Mythen MG, Miller TE, Edwards MR; Perioperative Quality Initiative-3 Workgroup; POQI chairs; Physiology group; Preoperative blood pressure group; Intraoperative blood pressure group; Postoperative blood pressure group.

Br J Anaesth. 2019 May;122(5):552-562. doi: 10.1016/j.bja.2019.01.018. Epub 2019 Mar 2.

PMID:
30916006
13.

Perioperative Quality Initiative consensus statement on intraoperative blood pressure, risk and outcomes for elective surgery.

Sessler DI, Bloomstone JA, Aronson S, Berry C, Gan TJ, Kellum JA, Plumb J, Mythen MG, Grocott MPW, Edwards MR, Miller TE; Perioperative Quality Initiative-3 workgroup; POQI chairs, Miller TE, Mythen MG, Grocott MP, Edwards MR; Physiology group; Preoperative blood pressure group; Intraoperative blood pressure group; Postoperative blood pressure group.

Br J Anaesth. 2019 May;122(5):563-574. doi: 10.1016/j.bja.2019.01.013. Epub 2019 Feb 27.

PMID:
30916004
14.

Perioperative Quality Initiative consensus statement on the physiology of arterial blood pressure control in perioperative medicine.

Ackland GL, Brudney CS, Cecconi M, Ince C, Irwin MG, Lacey J, Pinsky MR, Grocott MP, Mythen MG, Edwards MR, Miller TE; Perioperative Quality Initiative-3 workgroup; POQI chairs; Physiology group; Preoperative blood pressure group; Intraoperative blood pressure group; Postoperative blood pressure group.

Br J Anaesth. 2019 May;122(5):542-551. doi: 10.1016/j.bja.2019.01.011. Epub 2019 Feb 14.

PMID:
30916002
15.

Systematic review and consensus definitions for the Standardised Endpoints in Perioperative Medicine (StEP) initiative: infection and sepsis.

Barnes J, Hunter J, Harris S, Shankar-Hari M, Diouf E, Jammer I, Kalkman C, Klein AA, Corcoran T, Dieleman S, Grocott MPW, Mythen MG; StEP-COMPAC group.

Br J Anaesth. 2019 Apr;122(4):500-508. doi: 10.1016/j.bja.2019.01.009. Epub 2019 Feb 14.

17.

Metabolomic and lipidomic plasma profile changes in human participants ascending to Everest Base Camp.

O'Brien KA, Atkinson RA, Richardson L, Koulman A, Murray AJ, Harridge SDR, Martin DS, Levett DZH, Mitchell K, Mythen MG, Montgomery HE, Grocott MPW, Griffin JL, Edwards LM.

Sci Rep. 2019 Feb 19;9(1):2297. doi: 10.1038/s41598-019-38832-z.

18.

Choosing Wisely: just because we can, does it mean we should?

Santhirapala R, Fleisher LA, Grocott MPW.

Br J Anaesth. 2019 Mar;122(3):306-310. doi: 10.1016/j.bja.2018.11.025. Epub 2019 Jan 8. No abstract available.

PMID:
30770048
19.

Pushing arterial-venous plasma biomarkers to new heights: A model for personalised redox metabolomics?

Cumpstey AF, Minnion M, Fernandez BO, Mikus-Lelinska M, Mitchell K, Martin DS, Grocott MPW, Feelisch M; Xtreme Alps research group.

Redox Biol. 2019 Feb;21:101113. doi: 10.1016/j.redox.2019.101113. Epub 2019 Jan 22.

20.

Exercise prehabilitation may lead to augmented tumor regression following neoadjuvant chemoradiotherapy in locally advanced rectal cancer.

West MA, Astin R, Moyses HE, Cave J, White D, Levett DZH, Bates A, Brown G, Grocott MPW, Jack S.

Acta Oncol. 2019 May;58(5):588-595. doi: 10.1080/0284186X.2019.1566775. Epub 2019 Feb 6.

PMID:
30724668
21.

Immunonutrition for acute respiratory distress syndrome (ARDS) in adults.

Dushianthan A, Cusack R, Burgess VA, Grocott MP, Calder PC.

Cochrane Database Syst Rev. 2019 Jan 24;1:CD012041. doi: 10.1002/14651858.CD012041.pub2.

PMID:
30677127
22.

Protocol for a feasibility randomised controlled trial of targeted oxygen therapy in mechanically ventilated critically ill patients.

Martin DS, Brew-Graves C, McCartan N, Jell G, Potyka I, Stevens J, Williams NR, McNeil M, O'Driscoll BR, Mythen M, Grocott MPW.

BMJ Open. 2019 Jan 17;9(1):e021674. doi: 10.1136/bmjopen-2018-021674.

23.

Optimisation of Perioperative Cardiovascular Management to Improve Surgical Outcome II (OPTIMISE II) trial: study protocol for a multicentre international trial of cardiac output-guided fluid therapy with low-dose inotrope infusion compared with usual care in patients undergoing major elective gastrointestinal surgery.

Edwards MR, Forbes G, MacDonald N, Berdunov V, Mihaylova B, Dias P, Thomson A, Grocott MP, Mythen MG, Gillies MA, Sander M, Phan TD, Evered L, Wijeysundera DN, McCluskey SA, Aldecoa C, Ripollés-Melchor J, Hofer CK, Abukhudair H, Szczeklik W, Grigoras I, Hajjar LA, Kahan BC, Pearse RM; OPTIMISE II investigators.

BMJ Open. 2019 Jan 15;9(1):e023455. doi: 10.1136/bmjopen-2018-023455.

24.

Peri-operative care pathways: re-engineering care to achieve the 'triple aim'.

Grocott MPW, Edwards M, Mythen MG, Aronson S.

Anaesthesia. 2019 Jan;74 Suppl 1:90-99. doi: 10.1111/anae.14513. Review.

PMID:
30604413
25.

Patient optimisation before surgery: a clear and present challenge in peri-operative care.

Levy N, Grocott MPW, Carli F.

Anaesthesia. 2019 Jan;74 Suppl 1:3-6. doi: 10.1111/anae.14502. No abstract available.

PMID:
30604412
26.

Perioperative administration of buffered versus non-buffered crystalloid intravenous fluid to improve outcomes following adult surgical procedures: a Cochrane systematic review.

Odor PM, Bampoe S, Dushianthan A, Bennett-Guerrero E, Cro S, Gan TJ, Grocott MPW, James MFM, Mythen MG, O'Malley CMN, Roche AM, Rowan K, Burdett E.

Perioper Med (Lond). 2018 Dec 13;7:27. doi: 10.1186/s13741-018-0108-5. eCollection 2018. Review.

27.

Exercise interventions for people undergoing multimodal cancer treatment that includes surgery.

Loughney LA, West MA, Kemp GJ, Grocott MP, Jack S.

Cochrane Database Syst Rev. 2018 Dec 11;12:CD012280. doi: 10.1002/14651858.CD012280.pub2.

PMID:
30536366
28.

Organisational factors and mortality after an emergency laparotomy: multilevel analysis of 39 903 National Emergency Laparotomy Audit patients.

Oliver CM, Bassett MG, Poulton TE, Anderson ID, Murray DM, Grocott MP, Moonesinghe SR; National Emergency Laparotomy Audit collaborators.

Br J Anaesth. 2018 Dec;121(6):1346-1356. doi: 10.1016/j.bja.2018.07.040. Epub 2018 Oct 3.

PMID:
30442263
29.

Surgical Prehabilitation: Nutrition and Exercise.

Whittle J, Wischmeyer PE, Grocott MPW, Miller TE.

Anesthesiol Clin. 2018 Dec;36(4):567-580. doi: 10.1016/j.anclin.2018.07.013. Review.

PMID:
30390779
30.

Correction to: Intraoperative oxygenation in adult patients undergoing surgery (iOPS): a retrospective observational study across 29 UK hospitals.

Morkane CM, McKenna H, Cumpstey AF, Oldman AH, Grocott MPW, Martin DS; Pan London Perioperative Audit and Research Network (PLAN), South Coast Perioperative Audit and Research Collaboration (SPARC).

Perioper Med (Lond). 2018 Oct 24;7:26. doi: 10.1186/s13741-018-0106-7. eCollection 2018.

31.

Development and internal validation of a novel risk adjustment model for adult patients undergoing emergency laparotomy surgery: the National Emergency Laparotomy Audit risk model.

Eugene N, Oliver CM, Bassett MG, Poulton TE, Kuryba A, Johnston C, Anderson ID, Moonesinghe SR, Grocott MP, Murray DM, Cromwell DA, Walker K; NELA collaboration.

Br J Anaesth. 2018 Oct;121(4):739-748. doi: 10.1016/j.bja.2018.06.026. Epub 2018 Aug 23.

PMID:
30236236
32.

Replicating measurements of total hemoglobin mass (tHb-mass) within a single day: precision of measurement; feasibility and safety of using oxygen to expedite carbon monoxide clearance.

Plumb JOM, Kumar S, Otto J, Schmidt W, Richards T, Montgomery HE, Grocott MPW.

Physiol Rep. 2018 Sep;6(17):e13829. doi: 10.14814/phy2.13829.

33.

The Smell of Hypoxia: using an electronic nose at altitude and proof of concept of its role in the prediction and diagnosis of acute mountain sickness.

Lacey JRN, Kidel C, van der Kaaij JM, Brinkman P, Gilbert-Kawai ET, Grocott MPW, Mythen MG, Martin DS; Xtreme Everest 2 Research Group.

Physiol Rep. 2018 Sep;6(17):e13854. doi: 10.14814/phy2.13854.

34.

Assessment of functional capacity before major non-cardiac surgery: an international, prospective cohort study.

Wijeysundera DN, Pearse RM, Shulman MA, Abbott TEF, Torres E, Ambosta A, Croal BL, Granton JT, Thorpe KE, Grocott MPW, Farrington C, Myles PS, Cuthbertson BH; METS study investigators.

Lancet. 2018 Jun 30;391(10140):2631-2640. doi: 10.1016/S0140-6736(18)31131-0.

PMID:
30070222
35.

Intraoperative oxygenation in adult patients undergoing surgery (iOPS): a retrospective observational study across 29 UK hospitals.

Morkane CM, McKenna H, Cumpstey AF, Oldman AH, Grocott MPW, Martin DS; Pan London Perioperative Audit and Research Network (PLAN); South Coast Perioperative Audit and Research Collaboration (SPARC).

Perioper Med (Lond). 2018 Jul 24;7:17. doi: 10.1186/s13741-018-0098-3. eCollection 2018. Erratum in: Perioper Med (Lond). 2018 Oct 24;7:26. South Coast Perioperative Audit and Research Collaboration (SPARC) [added].

36.

A systematic review of the safety and efficacy of aerobic exercise during cytotoxic chemotherapy treatment.

Cave J, Paschalis A, Huang CY, West M, Copson E, Jack S, Grocott MPW.

Support Care Cancer. 2018 Oct;26(10):3337-3351. doi: 10.1007/s00520-018-4295-x. Epub 2018 Jun 24.

PMID:
29936624
37.

Abnormal liver phosphatidylcholine synthesis revealed in patients with acute respiratory distress syndrome.

Dushianthan A, Cusack R, Grocott MPW, Postle AD.

J Lipid Res. 2018 Jun;59(6):1034-1045. doi: 10.1194/jlr.P085050. Epub 2018 May 1.

38.

What are the optimum components in a care bundle aimed at reducing post-operative pulmonary complications in high-risk patients?

Griffiths SV, Conway DH; POPC-CB Investigators, Sander M, Jammer I, Grocott MPW, Creagh-Brown BC.

Perioper Med (Lond). 2018 Apr 17;7:7. doi: 10.1186/s13741-018-0084-9. eCollection 2018.

39.

Metabolic adjustment to high-altitude hypoxia: from genetic signals to physiological implications.

Murray AJ, Montgomery HE, Feelisch M, Grocott MPW, Martin DS.

Biochem Soc Trans. 2018 Jun 19;46(3):599-607. doi: 10.1042/BST20170502. Epub 2018 Apr 20. Review.

PMID:
29678953
40.

A systematic review and consensus definitions for standardised end-points in perioperative medicine: pulmonary complications.

Abbott TEF, Fowler AJ, Pelosi P, Gama de Abreu M, Møller AM, Canet J, Creagh-Brown B, Mythen M, Gin T, Lalu MM, Futier E, Grocott MP, Schultz MJ, Pearse RM; StEP-COMPAC Group.

Br J Anaesth. 2018 May;120(5):1066-1079. doi: 10.1016/j.bja.2018.02.007. Epub 2018 Mar 27.

41.

Tricks of the trade: delivering reliable healthcare.

Levett DZH, Grocott MPW.

Anaesthesia. 2018 Jun;73(6):671-674. doi: 10.1111/anae.14242. Epub 2018 Mar 26. No abstract available.

42.

Anesthetists (and Physicians) at Altitude.

Cumpstey AF, Milledge JS, Grocott MPW.

Int Anesthesiol Clin. 2018 Spring;56(2):47-64. doi: 10.1097/AIA.0000000000000184. Review. No abstract available.

PMID:
29521789
43.

Perioperative cardiopulmonary exercise testing (CPET): consensus clinical guidelines on indications, organization, conduct, and physiological interpretation.

Levett DZH, Jack S, Swart M, Carlisle J, Wilson J, Snowden C, Riley M, Danjoux G, Ward SA, Older P, Grocott MPW; Perioperative Exercise Testing and Training Society (POETTS).

Br J Anaesth. 2018 Mar;120(3):484-500. doi: 10.1016/j.bja.2017.10.020. Epub 2017 Nov 24.

44.

Inter-observer reliability of preoperative cardiopulmonary exercise test interpretation: a cross-sectional study.

Abbott TEF, Gooneratne M, McNeill J, Lee A, Levett DZH, Grocott MPW, Swart M, MacDonald N; ARCTIC study investigators.

Br J Anaesth. 2018 Mar;120(3):475-483. doi: 10.1016/j.bja.2017.11.071. Epub 2017 Nov 29.

45.

Perioperative structure and process quality and safety indicators: a systematic review.

Chazapis M, Gilhooly D, Smith AF, Myles PS, Haller G, Grocott MPW, Moonesinghe SR.

Br J Anaesth. 2018 Jan;120(1):51-66. doi: 10.1016/j.bja.2017.10.001. Epub 2017 Nov 24.

46.

Protocol for a randomised pilot multiple centre trial of conservative versus liberal oxygenation targets in critically ill children (Oxy-PICU).

Jones GAL, Ramnarayan P, Raman S, Inwald D, Grocott MPW, Eaton S, Ray S, Griksaitis MJ, Pappachan J, Wiley D, Mouncey PR, Wulff J, Harrison DA, Rowan KM, Peters MJ; Oxy-PICU Investigators for thePaediatric Intensive Care Society-Study Group (PICS-SG).

BMJ Open. 2017 Dec 14;7(12):e019253. doi: 10.1136/bmjopen-2017-019253.

47.

Prehabilitation and Nutritional Support to Improve Perioperative Outcomes.

West MA, Wischmeyer PE, Grocott MPW.

Curr Anesthesiol Rep. 2017;7(4):340-349. doi: 10.1007/s40140-017-0245-2. Epub 2017 Nov 7. Review.

48.

Fit for surgery? Perspectives on preoperative exercise testing and training.

Richardson K, Levett DZH, Jack S, Grocott MPW.

Br J Anaesth. 2017 Dec 1;119(suppl_1):i34-i43. doi: 10.1093/bja/aex393. Review.

49.

Effects of dietary nitrate on respiratory physiology at high altitude - Results from the Xtreme Alps study.

Cumpstey AF, Hennis PJ, Gilbert-Kawai ET, Fernandez BO, Poudevigne M, Cobb A, Meale P, Mitchell K, Moyses H, Pöhnl H, Mythen MG, Grocott MPW, Feelisch M, Martin DS; Xtreme Alps research group.

Nitric Oxide. 2017 Dec 1;71:57-68. doi: 10.1016/j.niox.2017.10.005. Epub 2017 Oct 16.

50.

Cohort study of preoperative blood pressure and risk of 30-day mortality after elective non-cardiac surgery.

Venkatesan S, Myles PR, Manning HJ, Mozid AM, Andersson C, Jørgensen ME, Hardman JG, Moonesinghe SR, Foex P, Mythen M, Grocott MPW, Sanders RD.

Br J Anaesth. 2017 Jul 1;119(1):174. doi: 10.1093/bja/aex223. No abstract available.

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