Format
Sort by
Items per page

Send to

Choose Destination

See also: GRN granulin precursor in the Gene database

grn in Homo sapiensMus musculusRattus norvegicusAll 241 Gene records

Search results

Items: 1 to 20 of 2108

1.

Approaches to develop therapeutics to treat frontotemporal dementia.

Elia LP, Reisine T, Alijagic A, Finkbeiner S.

Neuropharmacology. 2020 Jan 8;166:107948. doi: 10.1016/j.neuropharm.2020.107948. [Epub ahead of print] Review.

PMID:
31962288
2.

Lipid-droplet-accumulating microglia represent a dysfunctional and proinflammatory state in the aging brain.

Marschallinger J, Iram T, Zardeneta M, Lee SE, Lehallier B, Haney MS, Pluvinage JV, Mathur V, Hahn O, Morgens DW, Kim J, Tevini J, Felder TK, Wolinski H, Bertozzi CR, Bassik MC, Aigner L, Wyss-Coray T.

Nat Neurosci. 2020 Jan 20. doi: 10.1038/s41593-019-0566-1. [Epub ahead of print]

PMID:
31959936
3.

Novel Alzheimer risk genes determine the microglia response to amyloid-β but not to TAU pathology.

Sierksma A, Lu A, Mancuso R, Fattorelli N, Thrupp N, Salta E, Zoco J, Blum D, Buée L, De Strooper B, Fiers M.

EMBO Mol Med. 2020 Jan 17:e10606. doi: 10.15252/emmm.201910606. [Epub ahead of print]

4.

Stability and oscillation analysis of a gene regulatory network with multiple time delays and diffusion rate.

Dong T, Zhang Q.

IEEE Trans Nanobioscience. 2020 Jan 8. doi: 10.1109/TNB.2020.2964900. [Epub ahead of print]

PMID:
31944962
5.

Plasma glial fibrillary acidic protein is raised in progranulin-associated frontotemporal dementia.

Heller C, Foiani MS, Moore K, Convery R, Bocchetta M, Neason M, Cash DM, Thomas D, Greaves CV, Woollacott IO, Shafei R, Van Swieten JC, Moreno F, Sanchez-Valle R, Borroni B, Laforce R Jr, Masellis M, Tartaglia MC, Graff C, Galimberti D, Rowe JB, Finger E, Synofzik M, Vandenberghe R, de Mendonca A, Tagliavini F, Santana I, Ducharme S, Butler CR, Gerhard A, Levin J, Danek A, Frisoni G, Sorbi S, Otto M, Heslegrave AJ, Zetterberg H, Rohrer JD; GENFI.

J Neurol Neurosurg Psychiatry. 2020 Jan 14. pii: jnnp-2019-321954. doi: 10.1136/jnnp-2019-321954. [Epub ahead of print]

PMID:
31937580
6.

Autosomal-dominant adult neuronal ceroid lipofuscinosis caused by duplication in DNAJC5 initially missed by Sanger and whole-exome sequencing.

Jedličková I, Cadieux-Dion M, Přistoupilová A, Stránecký V, Hartmannová H, Hodaňová K, Barešová V, Hůlková H, Sikora J, Nosková L, Mušálková D, Vyleťal P, Sovová J, Cossette P, Andermann E, Andermann F, Kmoch S; Adult NCL Gene Discovery Consortium.

Eur J Hum Genet. 2020 Jan 9. doi: 10.1038/s41431-019-0567-2. [Epub ahead of print]

PMID:
31919451
7.

Trajectory of lobar atrophy in asymptomatic and symptomatic GRN mutation carriers: a longitudinal MRI study.

Chen Q, Boeve BF, Senjem M, Tosakulwong N, Lesnick T, Brushaber D, Dheel C, Fields J, Forsberg L, Gavrilova R, Gearhart D, Graff-Radford J, Graff-Radford N, Jack CR Jr, Jones D, Knopman D, Kremers WK, Lapid M, Rademakers R, Ramos EM, Syrjanen J, Boxer AL, Rosen H, Wszolek ZK, Kantarci K.

Neurobiol Aging. 2019 Dec 12. pii: S0197-4580(19)30432-4. doi: 10.1016/j.neurobiolaging.2019.12.004. [Epub ahead of print]

PMID:
31918955
8.

Bayesian differential analysis of gene regulatory networks exploiting genetic perturbations.

Li Y, Liu D, Li T, Zhu Y.

BMC Bioinformatics. 2020 Jan 9;21(1):12. doi: 10.1186/s12859-019-3314-3.

9.

Assessment of executive function declines in presymptomatic and mildly symptomatic familial frontotemporal dementia: NIH-EXAMINER as a potential clinical trial endpoint.

Staffaroni AM, Bajorek L, Casaletto KB, Cobigo Y, Goh SM, Wolf A, Heuer HW, Elahi FM, Ljubenkov PA, Dever R, Kornak J, Appleby B, Bove J, Bordelon Y, Brannelly P, Brushaber D, Caso C, Coppola G, Dheel C, Dickerson BC, Dickinson S, Dominguez S, Domoto-Reilly K, Faber K, Ferrall J, Fields JA, Fishman A, Fong J, Foroud T, Forsberg LK, Gavrilova R, Gearhart D, Ghazanfari B, Ghoshal N, Goldman J, Graff-Radford J, Graff-Radford N, Grant I, Grossman M, Haley D, Hsiung GY, Huey ED, Irwin DJ, Jones DT, Jones L, Kantarci K, Karydas A, Kaufer DI, Kerwin DR, Knopman DS, Kraft R, Kremers WK, Kukull WA, Litvan I, Lucente D, Lungu C, Mackenzie IR, Maldonado M, Manoochehri M, McGinnis SM, McKinley E, Mendez MF, Miller BL, Multani N, Onyike C, Padmanabhan J, Pantelyat A, Pearlman R, Petrucelli L, Potter M, Rademakers R, Ramos EM, Rankin KP, Rascovsky K, Roberson ED, Rogalski E, Sengdy P, Shaw LM, Syrjanen J, Tartaglia MC, Tatton N, Taylor J, Toga A, Trojanowski JQ, Weintraub S, Wang P, Wong B, Wszolek Z, Boxer AL, Boeve BF, Kramer JH, Rosen HJ; ARTFL/LEFFTDS consortium.

Alzheimers Dement. 2020 Jan;16(1):11-21. doi: 10.1016/j.jalz.2019.01.012.

PMID:
31914230
10.

Active lifestyles moderate clinical outcomes in autosomal dominant frontotemporal degeneration.

Casaletto KB, Staffaroni AM, Wolf A, Appleby B, Brushaber D, Coppola G, Dickerson B, Domoto-Reilly K, Elahi FM, Fields J, Fong JC, Forsberg L, Ghoshal N, Graff-Radford N, Grossman M, Heuer HW, Hsiung GY, Huey ED, Irwin D, Kantarci K, Kaufer D, Kerwin D, Knopman D, Kornak J, Kramer JH, Litvan I, Mackenzie IR, Mendez M, Miller B, Rademakers R, Ramos EM, Rascovsky K, Roberson ED, Syrjanen JA, Tartaglia MC, Weintraub S, Boeve B, Boxer AL, Rosen H, Yaffe K; ARTFL/LEFFTDS Study.

Alzheimers Dement. 2020 Jan;16(1):91-105. doi: 10.1002/alz.12001.

PMID:
31914227
11.

Comparison of sporadic and familial behavioral variant frontotemporal dementia (FTD) in a North American cohort.

Heuer HW, Wang P, Rascovsky K, Wolf A, Appleby B, Bove J, Bordelon Y, Brannelly P, Brushaber DE, Caso C, Coppola G, Dickerson B, Dickinson S, Domoto-Reilly K, Faber K, Ferrall J, Fields J, Fishman A, Fong J, Foroud T, Forsberg LK, Gearhart D, Ghazanfari B, Ghoshal N, Goldman J, Graff-Radford J, Graff-Radford N, Grant I, Grossman M, Haley D, Hsiung GY, Huey E, Irwin D, Jones D, Kantarci K, Karydas A, Kaufer D, Kerwin D, Knopman D, Kornak J, Kramer JH, Kraft R, Kremers WK, Kukull W, Litvan I, Ljubenkov P, Mackenzie IR, Maldonado M, Manoochehri M, McGinnis S, McKinley E, Mendez MF, Miller BL, Onyike C, Pantelyat A, Pearlman R, Petrucelli L, Potter M, Rademakers R, Ramos EM, Rankin KP, Roberson ED, Rogalski E, Sengdy P, Shaw L, Syrjanen J, Tartaglia MC, Tatton N, Taylor J, Toga A, Trojanowski J, Weintraub S, Wong B, Wszolek Z, Boeve BF, Rosen HJ, Boxer AL; ARTFL and LEFFTDS consortia.

Alzheimers Dement. 2020 Jan;16(1):60-70. doi: 10.1002/alz.12046.

PMID:
31914226
12.

Tracking disease progression in familial and sporadic frontotemporal lobar degeneration: Recent findings from ARTFL and LEFFTDS.

Rosen HJ, Boeve BF, Boxer AL.

Alzheimers Dement. 2020 Jan;16(1):71-78. doi: 10.1002/alz.12004. Review.

PMID:
31914219
13.

Genetic screening of a large series of North American sporadic and familial frontotemporal dementia cases.

Ramos EM, Dokuru DR, Van Berlo V, Wojta K, Wang Q, Huang AY, Deverasetty S, Qin Y, van Blitterswijk M, Jackson J, Appleby B, Bordelon Y, Brannelly P, Brushaber DE, Dickerson B, Dickinson S, Domoto-Reilly K, Faber K, Fields J, Fong J, Foroud T, Forsberg LK, Gavrilova R, Ghoshal N, Goldman J, Graff-Radford J, Graff-Radford N, Grant I, Grossman M, Heuer HW, Hsiung GR, Huey E, Irwin D, Kantarci K, Karydas A, Kaufer D, Kerwin D, Knopman D, Kornak J, Kramer JH, Kremers W, Kukull W, Litvan I, Ljubenkov P, Lungu C, Mackenzie I, Mendez MF, Miller BL, Onyike C, Pantelyat A, Pearlman R, Petrucelli L, Potter M, Rankin KP, Rascovsky K, Roberson ED, Rogalski E, Shaw L, Syrjanen J, Tartaglia MC, Tatton N, Taylor J, Toga A, Trojanowski JQ, Weintraub S, Wong B, Wszolek Z, Rademakers R, Boeve BF, Rosen HJ, Boxer AL; ARTFL/LEFFTDS consortium, Coppola G.

Alzheimers Dement. 2020 Jan;16(1):118-130. doi: 10.1002/alz.12011.

PMID:
31914217
14.

Granulins modulate liquid-liquid phase separation and aggregation of prion-like C-terminal domain of the neurodegeneration-associated protein TDP-43.

Bhopatkar AA, Uversky VN, Rangachari V.

J Biol Chem. 2020 Jan 6. pii: jbc.RA119.011501. doi: 10.1074/jbc.RA119.011501. [Epub ahead of print]

15.

Genome-wide analysis of PYL-PP2C-SnRK2s family in Camellia sinensis.

Xu P, Zhang X, Su H, Liu X, Wang Y, Hong G.

Bioengineered. 2020 Dec;11(1):103-115. doi: 10.1080/21655979.2019.1710932.

PMID:
31903833
16.

Network Inference Analysis Identifies SETDB1 as a Key Regulator for Reverting Colorectal Cancer Cells into Differentiated Normal-Like Cells.

Lee S, Lee C, Hwang CY, Kim D, Han Y, Hong SN, Kim SH, Cho KH.

Mol Cancer Res. 2020 Jan;18(1):118-129. doi: 10.1158/1541-7786.MCR-19-0450.

PMID:
31896605
17.

Multimodal MRI of grey matter, white matter, and functional connectivity in cognitively healthy mutation carriers at risk for frontotemporal dementia and Alzheimer's disease.

Feis RA, Bouts MJRJ, Dopper EGP, Filippini N, Heise V, Trachtenberg AJ, van Swieten JC, van Buchem MA, van der Grond J, Mackay CE, Rombouts SARB.

BMC Neurol. 2019 Dec 27;19(1):343. doi: 10.1186/s12883-019-1567-0.

18.

Impaired β-glucocerebrosidase activity and processing in frontotemporal dementia due to progranulin mutations.

Arrant AE, Roth JR, Boyle NR, Kashyap SN, Hoffmann MQ, Murchison CF, Ramos EM, Nana AL, Spina S, Grinberg LT, Miller BL, Seeley WW, Roberson ED.

Acta Neuropathol Commun. 2019 Dec 23;7(1):218. doi: 10.1186/s40478-019-0872-6.

19.

Characterization of lysosomal proteins Progranulin and Prosaposin and their interactions in Alzheimer's disease and aged brains: increased levels correlate with neuropathology.

Mendsaikhan A, Tooyama I, Bellier JP, Serrano GE, Sue LI, Lue LF, Beach TG, Walker DG.

Acta Neuropathol Commun. 2019 Dec 21;7(1):215. doi: 10.1186/s40478-019-0862-8.

20.

Homozygous GRN mutations: new phenotypes and new insights into pathological and molecular mechanisms.

Huin V, Barbier M, Bottani A, Lobrinus JA, Clot F, Lamari F, Chat L, Rucheton B, Fluchère F, Auvin S, Myers P, Gelot A, Camuzat A, Caillaud C, Jornéa L, Forlani S, Saracino D, Duyckaerts C, Brice A, Durr A, Le Ber I.

Brain. 2020 Jan 1;143(1):303-319. doi: 10.1093/brain/awz377.

PMID:
31855245

Supplemental Content

Support Center