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Items: 23


Anti-PSMA/CD3 Bispecific Antibody Delivery and Antitumor Activity Using a Polymeric Depot Formulation.

Leconet W, Liu H, Guo M, Le Lamer-Déchamps S, Molinier C, Kim S, Vrlinic T, Oster M, Liu F, Navarro V, Batra JS, Noriega AL, Grizot S, Bander NH.

Mol Cancer Ther. 2018 Sep;17(9):1927-1940. doi: 10.1158/1535-7163.MCT-17-1138. Epub 2018 Jun 11.


Crystal Structure of the Homing Endonuclease I-CvuI Provides a New Template for Genome Modification.

Molina R, Redondo P, López-Méndez B, Villate M, Merino N, Blanco FJ, Valton J, Grizot S, Duchateau P, Prieto J, Montoya G.

J Biol Chem. 2015 Nov 27;290(48):28727-36. doi: 10.1074/jbc.M115.678342. Epub 2015 Sep 11.


Non-specific protein-DNA interactions control I-CreI target binding and cleavage.

Molina R, Redondo P, Stella S, Marenchino M, D'Abramo M, Gervasio FL, Epinat JC, Valton J, Grizot S, Duchateau P, Prieto J, Montoya G.

Nucleic Acids Res. 2012 Aug;40(14):6936-45. doi: 10.1093/nar/gks320. Epub 2012 Apr 11.


Chromosomal context and epigenetic mechanisms control the efficacy of genome editing by rare-cutting designer endonucleases.

Daboussi F, Zaslavskiy M, Poirot L, Loperfido M, Gouble A, Guyot V, Leduc S, Galetto R, Grizot S, Oficjalska D, Perez C, Delacôte F, Dupuy A, Chion-Sotinel I, Le Clerre D, Lebuhotel C, Danos O, Lemaire F, Oussedik K, Cédrone F, Epinat JC, Smith J, Yáñez-Muñoz RJ, Dickson G, Popplewell L, Koo T, VandenDriessche T, Chuah MK, Duclert A, Duchateau P, Pâques F.

Nucleic Acids Res. 2012 Jul;40(13):6367-79. Epub 2012 Mar 29.


Context dependence between subdomains in the DNA binding interface of the I-CreI homing endonuclease.

Grizot S, Duclert A, Thomas S, Duchateau P, Pâques F.

Nucleic Acids Res. 2011 Aug;39(14):6124-36. doi: 10.1093/nar/gkr186. Epub 2011 Apr 10.


The I-CreI meganuclease and its engineered derivatives: applications from cell modification to gene therapy.

Arnould S, Delenda C, Grizot S, Desseaux C, Pâques F, Silva GH, Smith J.

Protein Eng Des Sel. 2011 Jan;24(1-2):27-31. doi: 10.1093/protein/gzq083. Epub 2010 Nov 3. Review.


Molecular basis of engineered meganuclease targeting of the endogenous human RAG1 locus.

Muñoz IG, Prieto J, Subramanian S, Coloma J, Redondo P, Villate M, Merino N, Marenchino M, D'Abramo M, Gervasio FL, Grizot S, Daboussi F, Smith J, Chion-Sotinel I, Pâques F, Duchateau P, Alibés A, Stricher F, Serrano L, Blanco FJ, Montoya G.

Nucleic Acids Res. 2011 Jan;39(2):729-43. doi: 10.1093/nar/gkq801. Epub 2010 Sep 16.


Generation of redesigned homing endonucleases comprising DNA-binding domains derived from two different scaffolds.

Grizot S, Epinat JC, Thomas S, Duclert A, Rolland S, Pâques F, Duchateau P.

Nucleic Acids Res. 2010 Apr;38(6):2006-18. doi: 10.1093/nar/gkp1171. Epub 2009 Dec 21.


Efficient targeting of a SCID gene by an engineered single-chain homing endonuclease.

Grizot S, Smith J, Daboussi F, Prieto J, Redondo P, Merino N, Villate M, Thomas S, Lemaire L, Montoya G, Blanco FJ, Pâques F, Duchateau P.

Nucleic Acids Res. 2009 Sep;37(16):5405-19. doi: 10.1093/nar/gkp548. Epub 2009 Jul 7.


Crystal structure of I-DmoI in complex with its target DNA provides new insights into meganuclease engineering.

Marcaida MJ, Prieto J, Redondo P, Nadra AD, Alibés A, Serrano L, Grizot S, Duchateau P, Pâques F, Blanco FJ, Montoya G.

Proc Natl Acad Sci U S A. 2008 Nov 4;105(44):16888-93. doi: 10.1073/pnas.0804795105. Epub 2008 Oct 30.


Stereoselective glycal fluorophosphorylation: synthesis of ADP-2-fluoroheptose, an inhibitor of the LPS biosynthesis.

Dohi H, Périon R, Durka M, Bosco M, Roué Y, Moreau F, Grizot S, Ducruix A, Escaich S, Vincent SP.

Chemistry. 2008;14(31):9530-9. doi: 10.1002/chem.200801279.


Engineered I-CreI derivatives cleaving sequences from the human XPC gene can induce highly efficient gene correction in mammalian cells.

Arnould S, Perez C, Cabaniols JP, Smith J, Gouble A, Grizot S, Epinat JC, Duclert A, Duchateau P, Pâques F.

J Mol Biol. 2007 Aug 3;371(1):49-65. Epub 2007 May 10.


Structure of colicin I receptor bound to the R-domain of colicin Ia: implications for protein import.

Buchanan SK, Lukacik P, Grizot S, Ghirlando R, Ali MM, Barnard TJ, Jakes KS, Kienker PK, Esser L.

EMBO J. 2007 May 16;26(10):2594-604. Epub 2007 Apr 26.


A combinatorial approach to create artificial homing endonucleases cleaving chosen sequences.

Smith J, Grizot S, Arnould S, Duclert A, Epinat JC, Chames P, Prieto J, Redondo P, Blanco FJ, Bravo J, Montoya G, Pâques F, Duchateau P.

Nucleic Acids Res. 2006;34(22):e149. Epub 2006 Nov 27.


Structure of the Escherichia coli heptosyltransferase WaaC: binary complexes with ADP and ADP-2-deoxy-2-fluoro heptose.

Grizot S, Salem M, Vongsouthi V, Durand L, Moreau F, Dohi H, Vincent S, Escaich S, Ducruix A.

J Mol Biol. 2006 Oct 20;363(2):383-94. Epub 2006 Jul 29.


Structure of the OmpA-like domain of RmpM from Neisseria meningitidis.

Grizot S, Buchanan SK.

Mol Microbiol. 2004 Feb;51(4):1027-37.


Detection and characterization of merohedral twinning in two protein crystals: bacteriorhodopsin and p67(phox).

Royant A, Grizot S, Kahn R, Belrhali H, Fieschi F, Landau EM, Pebay-Peyroula E.

Acta Crystallogr D Biol Crystallogr. 2002 May;58(Pt 5):784-91. Epub 2002 Apr 26.


Mechanism of NADPH oxidase activation by the Rac/Rho-GDI complex.

Di-Poï N, Fauré J, Grizot S, Molnár G, Pick E, Dagher MC.

Biochemistry. 2001 Aug 28;40(34):10014-22.


Crystal structure of the Rac1-RhoGDI complex involved in nadph oxidase activation.

Grizot S, Fauré J, Fieschi F, Vignais PV, Dagher MC, Pebay-Peyroula E.

Biochemistry. 2001 Aug 28;40(34):10007-13.


Small angle neutron scattering and gel filtration analyses of neutrophil NADPH oxidase cytosolic factors highlight the role of the C-terminal end of p47phox in the association with p40phox.

Grizot S, Grandvaux N, Fieschi F, Fauré J, Massenet C, Andrieu JP, Fuchs A, Vignais PV, Timmins PA, Dagher MC, Pebay-Peyroula E.

Biochemistry. 2001 Mar 13;40(10):3127-33.


The Ku70 autoantigen interacts with p40phox in B lymphocytes.

Grandvaux N, Grizot S, Vignais PV, Dagher MC.

J Cell Sci. 1999 Feb;112 ( Pt 4):503-13.

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