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Items: 1 to 50 of 194

1.

High school science fair: Student opinions regarding whether participation should be required or optional and why.

Grinnell F, Dalley S, Shepherd K, Reisch J.

PLoS One. 2018 Aug 10;13(8):e0202320. doi: 10.1371/journal.pone.0202320. eCollection 2018.

2.

Effects of dynamic matrix remodelling on en masse migration of fibroblasts on collagen matrices.

Ozcelikkale A, Dutton JC, Grinnell F, Han B.

J R Soc Interface. 2017 Oct;14(135). pii: 20170287. doi: 10.1098/rsif.2017.0287.

3.

Vascular disease-causing mutation, smooth muscle α-actin R258C, dominantly suppresses functions of α-actin in human patient fibroblasts.

Liu Z, Chang AN, Grinnell F, Trybus KM, Milewicz DM, Stull JT, Kamm KE.

Proc Natl Acad Sci U S A. 2017 Jul 11;114(28):E5569-E5578. doi: 10.1073/pnas.1703506114. Epub 2017 Jun 26.

4.

Confidence of IRB/REC Members in Their Assessments of Human Research Risk: A Study of IRB/REC Decision Making in Action.

Grinnell F, Sadler JZ, McNamara V, Senetar K, Reisch J.

J Empir Res Hum Res Ethics. 2017 Jul;12(3):140-149. doi: 10.1177/1556264617710386. Epub 2017 May 30.

PMID:
28558484
5.

High school science fair and research integrity.

Grinnell F, Dalley S, Shepherd K, Reisch J.

PLoS One. 2017 Mar 22;12(3):e0174252. doi: 10.1371/journal.pone.0174252. eCollection 2017.

6.

Rethink our approach to assessing risk.

Grinnell F.

Nature. 2015 Jun 18;522(7556):257. doi: 10.1038/522257a. No abstract available.

PMID:
26085235
7.

Preservation of tissue microstructure and functionality during freezing by modulation of cytoskeletal structure.

Park S, Seawright A, Park S, Craig Dutton J, Grinnell F, Han B.

J Mech Behav Biomed Mater. 2015 May;45:32-44. doi: 10.1016/j.jmbbm.2015.01.014. Epub 2015 Jan 24.

8.

PDGF‑stimulated dispersal of cell clusters and disruption of fibronectin matrix on three-dimensional collagen matrices requires matrix metalloproteinase-2.

da Rocha-Azevedo B, Ho CH, Grinnell F.

Mol Biol Cell. 2015 Mar 15;26(6):1098-105. doi: 10.1091/mbc.E14-09-1396. Epub 2015 Jan 14.

9.

The Interrelationship between Research Integrity, Conflict of Interest, and the Research Environment.

Grinnell F.

J Microbiol Biol Educ. 2014 Dec 15;15(2):162-4. doi: 10.1128/jmbe.v15i2.851. eCollection 2014 Dec.

10.

Introductory comments for the scientific ethics theme.

Fischer BA, Grinnell F, Zigmond MJ.

J Microbiol Biol Educ. 2014 Dec 15;15(2):82. doi: 10.1128/jmbe.v15i2.878. eCollection 2014 Dec. No abstract available.

11.

The different roles of myosin IIA and myosin IIB in contraction of 3D collagen matrices by human fibroblasts.

Liu Z, Ho CH, Grinnell F.

Exp Cell Res. 2014 Aug 15;326(2):295-306. doi: 10.1016/j.yexcr.2014.04.013. Epub 2014 Apr 25.

12.

Activation of MRTF-A-dependent gene expression with a small molecule promotes myofibroblast differentiation and wound healing.

Velasquez LS, Sutherland LB, Liu Z, Grinnell F, Kamm KE, Schneider JW, Olson EN, Small EM.

Proc Natl Acad Sci U S A. 2013 Oct 15;110(42):16850-5. doi: 10.1073/pnas.1316764110. Epub 2013 Sep 30.

13.

It is time to update US biomedical funding.

Grinnell F.

Nature. 2013 Sep 12;501(7466):137. doi: 10.1038/501137a. No abstract available.

PMID:
24025803
14.

Fibroblast morphogenesis on 3D collagen matrices: the balance between cell clustering and cell migration.

da Rocha-Azevedo B, Grinnell F.

Exp Cell Res. 2013 Oct 1;319(16):2440-6. doi: 10.1016/j.yexcr.2013.05.003. Epub 2013 May 9. Review.

15.

Thermomechanical analysis of freezing-induced cell-fluid-matrix interactions in engineered tissues.

Han B, Teo KY, Ghosh S, Dutton JC, Grinnell F.

J Mech Behav Biomed Mater. 2013 Feb;18:67-80. doi: 10.1016/j.jmbbm.2012.10.014. Epub 2012 Nov 10.

16.

The effect of growth factor environment on fibroblast morphological response to substrate stiffness.

Grinnell F, Ho CH.

Biomaterials. 2013 Jan;34(4):965-74. doi: 10.1016/j.biomaterials.2012.10.036. Epub 2012 Nov 9.

17.

Fibroblast cluster formation on 3D collagen matrices requires cell contraction dependent fibronectin matrix organization.

da Rocha-Azevedo B, Ho CH, Grinnell F.

Exp Cell Res. 2013 Feb 15;319(4):546-55. doi: 10.1016/j.yexcr.2012.10.005. Epub 2012 Oct 29.

18.

Research integrity and everyday practice of science.

Grinnell F.

Sci Eng Ethics. 2013 Sep;19(3):685-701. doi: 10.1007/s11948-012-9376-5. Epub 2012 Jun 28.

PMID:
22740035
19.

Effects of freezing-induced cell-fluid-matrix interactions on the cells and extracellular matrix of engineered tissues.

Teo KY, DeHoyos TO, Dutton JC, Grinnell F, Han B.

Biomaterials. 2011 Aug;32(23):5380-90. doi: 10.1016/j.biomaterials.2011.04.008. Epub 2011 May 5.

20.

The differential regulation of cell motile activity through matrix stiffness and porosity in three dimensional collagen matrices.

Miron-Mendoza M, Seemann J, Grinnell F.

Biomaterials. 2010 Sep;31(25):6425-35. doi: 10.1016/j.biomaterials.2010.04.064.

21.

Promigratory and procontractile growth factor environments differentially regulate cell morphogenesis.

Rhee S, Ho CH, Grinnell F.

Exp Cell Res. 2010 Jan 15;316(2):232-44. doi: 10.1016/j.yexcr.2009.09.021. Epub 2009 Sep 29.

22.

Cell motility and mechanics in three-dimensional collagen matrices.

Grinnell F, Petroll WM.

Annu Rev Cell Dev Biol. 2010;26:335-61. doi: 10.1146/annurev.cellbio.042308.113318. Review.

PMID:
19575667
23.

Discovery in the lab: Plato's paradox and Delbrück's principle of limited sloppiness.

Grinnell F.

FASEB J. 2009 Jan;23(1):7-9. doi: 10.1096/fj.09-0102ufm. No abstract available.

PMID:
19118078
24.

Fibroblast mechanics in three-dimensional collagen matrices.

Grinnell F.

J Bodyw Mov Ther. 2008 Jul;12(3):191-3. doi: 10.1016/j.jbmt.2008.03.005. Epub 2008 May 23. Review.

25.

Oncogenic Ras-transformed human fibroblasts exhibit differential changes in contraction and migration in 3D collagen matrices.

Menezes GC, Miron-Mendoza M, Ho CH, Jiang H, Grinnell F.

Exp Cell Res. 2008 Oct 1;314(16):3081-91. doi: 10.1016/j.yexcr.2008.07.018. Epub 2008 Jul 26.

26.

Collagen fibril flow and tissue translocation coupled to fibroblast migration in 3D collagen matrices.

Miron-Mendoza M, Seemann J, Grinnell F.

Mol Biol Cell. 2008 May;19(5):2051-8. doi: 10.1091/mbc.E07-09-0930. Epub 2008 Mar 5.

27.

Distinguishing fibroblast promigratory and procontractile growth factor environments in 3-D collagen matrices.

Jiang H, Rhee S, Ho CH, Grinnell F.

FASEB J. 2008 Jul;22(7):2151-60. doi: 10.1096/fj.07-097014. Epub 2008 Feb 13.

PMID:
18272655
28.

Fibroblast mechanics in 3D collagen matrices.

Rhee S, Grinnell F.

Adv Drug Deliv Rev. 2007 Nov 10;59(13):1299-305. Epub 2007 Aug 14. Review.

29.

Microtubule function in fibroblast spreading is modulated according to the tension state of cell-matrix interactions.

Rhee S, Jiang H, Ho CH, Grinnell F.

Proc Natl Acad Sci U S A. 2007 Mar 27;104(13):5425-30. Epub 2007 Mar 16.

30.

Intelligent design: fallacy recapitulates ontogeny.

Grinnell F.

FASEB J. 2006 Mar;20(3):410-1. No abstract available.

PMID:
16507757
32.

Nested collagen matrices: a new model to study migration of human fibroblast populations in three dimensions.

Grinnell F, Rocha LB, Iucu C, Rhee S, Jiang H.

Exp Cell Res. 2006 Jan 1;312(1):86-94. Epub 2005 Oct 27.

PMID:
16256985
33.

Subject vulnerability: the precautionary principle of human research.

Grinnell F.

Am J Bioeth. 2004 Summer;4(3):72-4; discussion W32. No abstract available.

PMID:
16192151
34.

Cell-matrix entanglement and mechanical anchorage of fibroblasts in three-dimensional collagen matrices.

Jiang H, Grinnell F.

Mol Biol Cell. 2005 Nov;16(11):5070-6. Epub 2005 Aug 17.

35.

Misconduct: acceptable practices differ by field.

Grinnell F.

Nature. 2005 Aug 11;436(7052):776. No abstract available.

PMID:
16094343
36.

Defining embryo death would permit important research.

Grinnell F.

Chron High Educ. 2003 May 16;49(36):B13. No abstract available.

PMID:
15287127
37.

Human embryo research: from moral uncertainty to death.

Grinnell F.

Am J Bioeth. 2004 Winter;4(1):12-3. No abstract available.

PMID:
15035923
38.
40.

Fibroblast biology in three-dimensional collagen matrices.

Grinnell F.

Trends Cell Biol. 2003 May;13(5):264-9. Review.

PMID:
12742170
41.

Fibroblast quiescence in floating collagen matrices: decrease in serum activation of MEK and Raf but not Ras.

Fringer J, Grinnell F.

J Biol Chem. 2003 Jun 6;278(23):20612-7. Epub 2003 Mar 27.

42.

Dendritic fibroblasts in three-dimensional collagen matrices.

Grinnell F, Ho CH, Tamariz E, Lee DJ, Skuta G.

Mol Biol Cell. 2003 Feb;14(2):384-95.

43.

Modulation of fibroblast morphology and adhesion during collagen matrix remodeling.

Tamariz E, Grinnell F.

Mol Biol Cell. 2002 Nov;13(11):3915-29.

44.

Bioethical pluralism and complementarity.

Grinnell F, Bishop JP, McCullough LB.

Perspect Biol Med. 2002 Summer;45(3):338-49. Review.

PMID:
12114829
46.

Ambiguity, trust, and the responsible conduct of research.

Grinnell F.

Sci Eng Ethics. 1999 Apr;5(2):205-14. No abstract available.

PMID:
11657858
47.
48.

Fibroblast-collagen-matrix contraction: growth-factor signalling and mechanical loading.

Grinnell F.

Trends Cell Biol. 2000 Sep;10(9):362-5. Review.

PMID:
10932093
49.

Activation of ERK and p38 MAP kinases in human fibroblasts during collagen matrix contraction.

Lee DJ, Rosenfeldt H, Grinnell F.

Exp Cell Res. 2000 May 25;257(1):190-7.

PMID:
10854067
50.

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