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Items: 22

1.

Safety of purified poloxamer 188 in sickle cell disease: phase I study of a non-ionic surfactant in the management of acute chest syndrome.

Ballas SK, Files B, Luchtman-Jones L, Benjamin L, Swerdlow P, Hilliard L, Coates T, Abboud M, Wojtowicz-Praga S, Grindel JM.

Hemoglobin. 2004 May;28(2):85-102.

PMID:
15182051
2.

Clinical studies in patients with solid tumors using a second-generation antisense oligonucleotide (GEM 231) targeted against protein kinase A type I.

Mani S, Goel S, Nesterova M, Martin RM, Grindel JM, Rothenberg ML, Zhang R, Tortora G, Cho-Chung YS.

Ann N Y Acad Sci. 2003 Dec;1002:252-62.

PMID:
14751840
3.

Distribution, metabolism, and excretion of a novel surface-active agent, purified poloxamer 188, in rats, dogs, and humans.

Grindel JM, Jaworski T, Piraner O, Emanuele RM, Balasubramanian M.

J Pharm Sci. 2002 Sep;91(9):1936-47.

PMID:
12210041
4.

Pharmacokinetics of a novel surface-active agent, purified poloxamer 188, in rat, rabbit, dog and man.

Grindel JM, Jaworski T, Emanuele RM, Culbreth P.

Biopharm Drug Dispos. 2002 Apr;23(3):87-103.

PMID:
12173548
5.

Purified poloxamer 188 for treatment of acute vaso-occlusive crisis of sickle cell disease: A randomized controlled trial.

Orringer EP, Casella JF, Ataga KI, Koshy M, Adams-Graves P, Luchtman-Jones L, Wun T, Watanabe M, Shafer F, Kutlar A, Abboud M, Steinberg M, Adler B, Swerdlow P, Terregino C, Saccente S, Files B, Ballas S, Brown R, Wojtowicz-Praga S, Grindel JM.

JAMA. 2001 Nov 7;286(17):2099-106.

PMID:
11694150
6.

Toxicological evaluation of oligonucleotide therapeutics.

Marquis JK, Grindel JM.

Curr Opin Mol Ther. 2000 Jun;2(3):258-63. Review.

PMID:
11249619
7.

Pharmacokinetics and metabolism of an oligodeoxynucleotide phosphorothioate (GEM91) in cynomolgus monkeys following intravenous infusion.

Grindel JM, Musick TJ, Jiang Z, Roskey A, Agrawal S.

Antisense Nucleic Acid Drug Dev. 1998 Feb;8(1):43-52.

PMID:
9512095
8.

Plasma levels, biotransformation and excretion of oxatomide (R 35 443) in rats, dogs and man.

Meuldermans W, Hendrickx J, Knaeps F, Lauwers W, Heykants J, Grindel JM.

Xenobiotica. 1984 Jun;14(6):445-62.

PMID:
6475104
9.

Reversed-phase high-performance liquid chromatographic assay for zomepirac in urine.

Grindel JM, Hills JF, Renzi NL.

J Chromatogr. 1983 Jan 14;272(1):210-5. No abstract available.

PMID:
6841543
10.

Pharmacokinetics and metabolism of tolmetin in normal and adjuvant arthritic Lewis rats.

Grindel JM, Migdalof BH, Yorgey KA, Pritchard JF.

Eur J Drug Metab Pharmacokinet. 1982 Oct-Dec;7(4):299-306. No abstract available.

PMID:
6984679
11.

The pharmacokinetic and metabolic profile of the antiinflammatory agent tolmetin in laboratory animals and man.

Grindel JM.

Drug Metab Rev. 1981;12(2):363-77. Review. No abstract available.

PMID:
7040019
12.

The metabolism of zomepirac sodium. II. Isolation and identification of the urinary metabolites in rat, mouse, rhesus monkey, and man.

Wu WN, Weaner LE, Kalbron J, O'Neill PJ, Grindel JM.

Drug Metab Dispos. 1980 Sep-Oct;8(5):349-52.

PMID:
6107234
13.

The metabolism of zomepirac sodium. I. Disposition in laboratory animals and man.

Grindel JM, O'Neill PJ, Yorgey KA, Schwartz MH, McKown LA, Migdalof BH, Wu WN.

Drug Metab Dispos. 1980 Sep-Oct;8(5):343-8.

PMID:
6107233
14.

Review of the pharmacokinetics and metabolism of zomepirac in man and animals.

Muschek LD, Grindel JM.

J Clin Pharmacol. 1980 Apr;20(4):223-9. Review.

PMID:
6769977
15.

Characterization of a new urinary metabolite of penfluridol in the rat, rabbit, dog, and man.

Grindel JM, Migdalof BH, Hills JF.

Drug Metab Dispos. 1979 Nov-Dec;7(6):448. No abstract available.

PMID:
43238
16.

The comparative metabolism and disposition of penfluridol-3H in the rat, rabbit, dog, and man.

Grindel JM, Migdalof BH, Cressman WA.

Drug Metab Dispos. 1979 Sep-Oct;7(5):325-9.

PMID:
40775
17.

Absorption and excretion of tolmetin in arthritic patients.

Grindel JM, Migdalof BH, Plostnieks J.

Clin Pharmacol Ther. 1979 Jul;26(1):122-8.

PMID:
445955
18.

Penfluridol: a neuroleptic drug designed for long duration of action.

Migdalof BH, Grindel JM, Heykants JJ, Janssen PA.

Drug Metab Rev. 1979;9(2):281-99. Review.

PMID:
385274
19.
22.

Importance of the aromatic ring in adrenergic amines. Nonaromatic analoques of phenylethanolamine as substrates for phenylethanolamine N-methyltransferase.

Grunewald GL, Grindel JM, Vincek WC, Borchardt RT.

Mol Pharmacol. 1975 Sep;11(5):694-9. No abstract available.

PMID:
1237082

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