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Items: 38


CDK2 kinase activity is a regulator of male germ cell fate.

Singh P, Patel RK, Palmer N, Grenier JK, Paduch D, Kaldis P, Grimson A, Schimenti JC.

Development. 2019 Nov 6;146(21). pii: dev180273. doi: 10.1242/dev.180273.


Aberrant gene expression by Sertoli cells in infertile men with Sertoli cell-only syndrome.

Paduch DA, Hilz S, Grimson A, Schlegel PN, Jedlicka AE, Wright WW.

PLoS One. 2019 May 9;14(5):e0216586. doi: 10.1371/journal.pone.0216586. eCollection 2019. Erratum in: PLoS One. 2019 Aug 20;14(8):e0221648.


Tumor-secreted extracellular vesicles promote the activation of cancer-associated fibroblasts via the transfer of microRNA-125b.

Vu LT, Peng B, Zhang DX, Ma V, Mathey-Andrews CA, Lam CK, Kiomourtzis T, Jin J, McReynolds L, Huang L, Grimson A, Cho WC, Lieberman J, Le MT.

J Extracell Vesicles. 2019 Apr 14;8(1):1599680. doi: 10.1080/20013078.2019.1599680. eCollection 2019.


The Notch signaling pathway promotes basophil responses during helminth-induced type 2 inflammation.

Webb LM, Oyesola OO, Früh SP, Kamynina E, Still KM, Patel RK, Peng SA, Cubitt RL, Grimson A, Grenier JK, Harris TH, Danko CG, Tait Wojno ED.

J Exp Med. 2019 Jun 3;216(6):1268-1279. doi: 10.1084/jem.20180131. Epub 2019 Apr 11.


Dynamic transcriptome profiles within spermatogonial and spermatocyte populations during postnatal testis maturation revealed by single-cell sequencing.

Grive KJ, Hu Y, Shu E, Grimson A, Elemento O, Grenier JK, Cohen PE.

PLoS Genet. 2019 Mar 20;15(3):e1007810. doi: 10.1371/journal.pgen.1007810. eCollection 2019 Mar.


MiR-146a wild-type 3' sequence identity is dispensable for proper innate immune function in vivo.

Bertolet G, Kongchan N, Miller R, Patel RK, Jain A, Choi JM, Saltzman AB, Christenson A, Jung SY, Malovannaya A, Grimson A, Neilson JR.

Life Sci Alliance. 2019 Feb 18;2(1). pii: e201800249. doi: 10.26508/lsa.201800249. Print 2019 Feb.


Developmental Origin Governs CD8+ T Cell Fate Decisions during Infection.

Smith NL, Patel RK, Reynaldi A, Grenier JK, Wang J, Watson NB, Nzingha K, Yee Mon KJ, Peng SA, Grimson A, Davenport MP, Rudd BD.

Cell. 2018 Jun 28;174(1):117-130.e14. doi: 10.1016/j.cell.2018.05.029. Epub 2018 Jun 14.


Characterizing mRNA Sequence Motifs in the 3'-UTR Using GFP Reporter Constructs.

Geissler R, Grimson A.

Methods Mol Biol. 2018;1720:77-88. doi: 10.1007/978-1-4939-7540-2_6.


Fetal and adult progenitors give rise to unique populations of CD8+ T cells.

Wang J, Wissink EM, Watson NB, Smith NL, Grimson A, Rudd BD.

Blood. 2016 Dec 29;128(26):3073-3082. doi: 10.1182/blood-2016-06-725366. Epub 2016 Nov 15.


Transcriptome profiling of the developing male germ line identifies the miR-29 family as a global regulator during meiosis.

Hilz S, Fogarty EA, Modzelewski AJ, Cohen PE, Grimson A.

RNA Biol. 2017 Feb;14(2):219-235. doi: 10.1080/15476286.2016.1270002. Epub 2016 Dec 16.


A position-specific 3'UTR sequence that accelerates mRNA decay.

Geissler R, Grimson A.

RNA Biol. 2016 Nov;13(11):1075-1077. Epub 2016 Aug 26. Review.


Integrated network analysis reveals distinct regulatory roles of transcription factors and microRNAs.

Guo Y, Alexander K, Clark AG, Grimson A, Yu H.

RNA. 2016 Nov;22(11):1663-1672. Epub 2016 Sep 7.


The roles of microRNAs and siRNAs in mammalian spermatogenesis.

Hilz S, Modzelewski AJ, Cohen PE, Grimson A.

Development. 2016 Sep 1;143(17):3061-73. doi: 10.1242/dev.136721. Review.


A widespread sequence-specific mRNA decay pathway mediated by hnRNPs A1 and A2/B1.

Geissler R, Simkin A, Floss D, Patel R, Fogarty EA, Scheller J, Grimson A.

Genes Dev. 2016 May 1;30(9):1070-85. doi: 10.1101/gad.277392.116.


High-throughput discovery of post-transcriptional cis-regulatory elements.

Wissink EM, Fogarty EA, Grimson A.

BMC Genomics. 2016 Mar 3;17:177. doi: 10.1186/s12864-016-2479-7.


A Proteome-wide Fission Yeast Interactome Reveals Network Evolution Principles from Yeasts to Human.

Vo TV, Das J, Meyer MJ, Cordero NA, Akturk N, Wei X, Fair BJ, Degatano AG, Fragoza R, Liu LG, Matsuyama A, Trickey M, Horibata S, Grimson A, Yamano H, Yoshida M, Roth FP, Pleiss JA, Xia Y, Yu H.

Cell. 2016 Jan 14;164(1-2):310-323. doi: 10.1016/j.cell.2015.11.037.


miR-150 Regulates Differentiation and Cytolytic Effector Function in CD8+ T cells.

Smith NL, Wissink EM, Grimson A, Rudd BD.

Sci Rep. 2015 Nov 9;5:16399. doi: 10.1038/srep16399.


MicroRNAs and Their Targets Are Differentially Regulated in Adult and Neonatal Mouse CD8+ T Cells.

Wissink EM, Smith NL, Spektor R, Rudd BD, Grimson A.

Genetics. 2015 Nov;201(3):1017-30. doi: 10.1534/genetics.115.179176. Epub 2015 Sep 28.


Widespread alternative and aberrant splicing revealed by lariat sequencing.

Stepankiw N, Raghavan M, Fogarty EA, Grimson A, Pleiss JA.

Nucleic Acids Res. 2015 Sep 30;43(17):8488-501. doi: 10.1093/nar/gkv763. Epub 2015 Aug 10.


miRNA-embedded shRNAs for Lineage-specific BCL11A Knockdown and Hemoglobin F Induction.

Guda S, Brendel C, Renella R, Du P, Bauer DE, Canver MC, Grenier JK, Grimson AW, Kamran SC, Thornton J, de Boer H, Root DE, Milsom MD, Orkin SH, Gregory RI, Williams DA.

Mol Ther. 2015 Sep;23(9):1465-74. doi: 10.1038/mt.2015.113. Epub 2015 Jun 17.


Systematic analysis of the Hmga2 3' UTR identifies many independent regulatory sequences and a novel interaction between distal sites.

Kristjánsdóttir K, Fogarty EA, Grimson A.

RNA. 2015 Jul;21(7):1346-60. doi: 10.1261/rna.051177.115. Epub 2015 May 21.


Dgcr8 and Dicer are essential for sex chromosome integrity during meiosis in males.

Modzelewski AJ, Hilz S, Crate EA, Schweidenback CT, Fogarty EA, Grenier JK, Freire R, Cohen PE, Grimson A.

J Cell Sci. 2015 Jun 15;128(12):2314-27. doi: 10.1242/jcs.167148. Epub 2015 May 1.


Noncoding RNA: linking microRNAs to their targets.

Grimson A.

Nat Chem Biol. 2015 Feb;11(2):100-1. doi: 10.1038/nchembio.1741. No abstract available.


Rapid proliferation and differentiation impairs the development of memory CD8+ T cells in early life.

Smith NL, Wissink E, Wang J, Pinello JF, Davenport MP, Grimson A, Rudd BD.

J Immunol. 2014 Jul 1;193(1):177-84. doi: 10.4049/jimmunol.1400553. Epub 2014 May 21.


Dissecting disease inheritance modes in a three-dimensional protein network challenges the "guilt-by-association" principle.

Guo Y, Wei X, Das J, Grimson A, Lipkin SM, Clark AG, Yu H.

Am J Hum Genet. 2013 Jul 11;93(1):78-89. doi: 10.1016/j.ajhg.2013.05.022. Epub 2013 Jun 20.


AGO4 regulates entry into meiosis and influences silencing of sex chromosomes in the male mouse germline.

Modzelewski AJ, Holmes RJ, Hilz S, Grimson A, Cohen PE.

Dev Cell. 2012 Aug 14;23(2):251-64. doi: 10.1016/j.devcel.2012.07.003. Epub 2012 Aug 2.


Weak seed-pairing stability and high target-site abundance decrease the proficiency of lsy-6 and other microRNAs.

Garcia DM, Baek D, Shin C, Bell GW, Grimson A, Bartel DP.

Nat Struct Mol Biol. 2011 Sep 11;18(10):1139-46. doi: 10.1038/nsmb.2115.


A targeted approach to miRNA target identification.

Grimson A.

Nat Methods. 2010 Oct;7(10):795-7. doi: 10.1038/nmeth1010-795. Epub 2010 Sep 29. No abstract available.


Early origins and evolution of microRNAs and Piwi-interacting RNAs in animals.

Grimson A, Srivastava M, Fahey B, Woodcroft BJ, Chiang HR, King N, Degnan BM, Rokhsar DS, Bartel DP.

Nature. 2008 Oct 30;455(7217):1193-7. doi: 10.1038/nature07415. Epub 2008 Oct 1.


MicroRNA targeting specificity in mammals: determinants beyond seed pairing.

Grimson A, Farh KK, Johnston WK, Garrett-Engele P, Lim LP, Bartel DP.

Mol Cell. 2007 Jul 6;27(1):91-105.


Caenorhabditis elegans SMG-2 selectively marks mRNAs containing premature translation termination codons.

Johns L, Grimson A, Kuchma SL, Newman CL, Anderson P.

Mol Cell Biol. 2007 Aug;27(16):5630-8. Epub 2007 Jun 11.


The widespread impact of mammalian MicroRNAs on mRNA repression and evolution.

Farh KK, Grimson A, Jan C, Lewis BP, Johnston WK, Lim LP, Burge CB, Bartel DP.

Science. 2005 Dec 16;310(5755):1817-21. Epub 2005 Nov 24.


CAR-1, a protein that localizes with the mRNA decapping component DCAP-1, is required for cytokinesis and ER organization in Caenorhabditis elegans embryos.

Squirrell JM, Eggers ZT, Luedke N, Saari B, Grimson A, Lyons GE, Anderson P, White JG.

Mol Biol Cell. 2006 Jan;17(1):336-44. Epub 2005 Nov 2.


Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs.

Lim LP, Lau NC, Garrett-Engele P, Grimson A, Schelter JM, Castle J, Bartel DP, Linsley PS, Johnson JM.

Nature. 2005 Feb 17;433(7027):769-73. Epub 2005 Jan 30.


Phosphorylation of hUPF1 induces formation of mRNA surveillance complexes containing hSMG-5 and hSMG-7.

Ohnishi T, Yamashita A, Kashima I, Schell T, Anders KR, Grimson A, Hachiya T, Hentze MW, Anderson P, Ohno S.

Mol Cell. 2003 Nov;12(5):1187-200.


SMG-2 is a phosphorylated protein required for mRNA surveillance in Caenorhabditis elegans and related to Upf1p of yeast.

Page MF, Carr B, Anders KR, Grimson A, Anderson P.

Mol Cell Biol. 1999 Sep;19(9):5943-51.

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