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Items: 1 to 50 of 55

1.

A distal super enhancer mediates estrogen-dependent mouse uterine-specific gene transcription of Igf1 (insulin-like growth factor 1).

Hewitt SC, Lierz SL, Garcia M, Hamilton KJ, Gruzdev A, Grimm SA, Lydon JP, Demayo FJ, Korach KS.

J Biol Chem. 2019 Jun 21;294(25):9746-9759. doi: 10.1074/jbc.RA119.008759. Epub 2019 May 9.

PMID:
31073032
2.

Long-term glioblastoma survival following recovery from cytomegalovirus colitis: A case report.

Lamano JB, Quaggin-Smith JA, Horbinski CM, Tate MC, Grimm SA, Kumthekar PU, Bloch O.

J Clin Neurosci. 2019 Jun;64:18-21. doi: 10.1016/j.jocn.2019.03.051. Epub 2019 Apr 1.

PMID:
30948314
3.

DNA methylation in mice is influenced by genetics as well as sex and life experience.

Grimm SA, Shimbo T, Takaku M, Thomas JW, Auerbach S, Bennett BD, Bucher JR, Burkholder AB, Day F, Du Y, Duncan CG, French JE, Foley JF, Li J, Merrick BA, Tice RR, Wang T, Xu X; NISC Comparative Sequencing Program, Bushel PR, Fargo DC, Mullikin JC, Wade PA.

Nat Commun. 2019 Jan 18;10(1):305. doi: 10.1038/s41467-018-08067-z.

4.

Crohn's disease IRGM risk alleles are associated with altered gene expression in human tissues.

Ajayi TA, Innes CL, Grimm SA, Rai P, Finethy R, Coers J, Wang X, Bell DA, McGrath JA, Schurman SH, Fessler MB.

Am J Physiol Gastrointest Liver Physiol. 2019 Jan 1;316(1):G95-G105. doi: 10.1152/ajpgi.00196.2018. Epub 2018 Oct 18.

PMID:
30335469
5.

Genome-wide identification of FOXL2 binding and characterization of FOXL2 feminizing action in the fetal gonads.

Nicol B, Grimm SA, Gruzdev A, Scott GJ, Ray MK, Yao HH.

Hum Mol Genet. 2018 Dec 15;27(24):4273-4287. doi: 10.1093/hmg/ddy312.

PMID:
30212841
6.

Revealing a human p53 universe.

Nguyen TT, Grimm SA, Bushel PR, Li J, Li Y, Bennett BD, Lavender CA, Ward JM, Fargo DC, Anderson CW, Li L, Resnick MA, Menendez D.

Nucleic Acids Res. 2018 Sep 19;46(16):8153-8167. doi: 10.1093/nar/gky720.

7.

Dosage compensation and DNA methylation landscape of the X chromosome in mouse liver.

Duncan CG, Grimm SA, Morgan DL, Bushel PR, Bennett BD; NISC Comparative Sequencing Program, Roberts JD, Tyson FL, Merrick BA, Wade PA.

Sci Rep. 2018 Jul 4;8(1):10138. doi: 10.1038/s41598-018-28356-3.

8.

Loss of Glis3 causes dysregulation of retrotransposon silencing and germ cell demise in fetal mouse testis.

Ungewitter EK, Rotgers E, Kang HS, Lichti-Kaiser K, Li L, Grimm SA, Jetten AM, Yao HH.

Sci Rep. 2018 Jun 25;8(1):9662. doi: 10.1038/s41598-018-27843-x.

9.

Muver, a computational framework for accurately calling accumulated mutations.

Burkholder AB, Lujan SA, Lavender CA, Grimm SA, Kunkel TA, Fargo DC.

BMC Genomics. 2018 May 9;19(1):345. doi: 10.1186/s12864-018-4753-3.

10.

DNA methylation and transcriptome aberrations mediated by ERα in mouse seminal vesicles following developmental DES exposure.

Li Y, Hamilton KJ, Wang T, Coons LA, Jefferson WN, Li R, Wang Y, Grimm SA, Ramsey JT, Liu L, Gerrish KE, Williams CJ, Wade PA, Korach KS.

Proc Natl Acad Sci U S A. 2018 May 1;115(18):E4189-E4198. doi: 10.1073/pnas.1719010115. Epub 2018 Apr 16.

11.

GATA3 zinc finger 2 mutations reprogram the breast cancer transcriptional network.

Takaku M, Grimm SA, Roberts JD, Chrysovergis K, Bennett BD, Myers P, Perera L, Tucker CJ, Perou CM, Wade PA.

Nat Commun. 2018 Mar 13;9(1):1059. doi: 10.1038/s41467-018-03478-4.

12.

An obesity-associated gut microbiome reprograms the intestinal epigenome and leads to altered colonic gene expression.

Qin Y, Roberts JD, Grimm SA, Lih FB, Deterding LJ, Li R, Chrysovergis K, Wade PA.

Genome Biol. 2018 Jan 23;19(1):7. doi: 10.1186/s13059-018-1389-1.

13.

Transcriptome and DNA Methylome Analysis in a Mouse Model of Diet-Induced Obesity Predicts Increased Risk of Colorectal Cancer.

Li R, Grimm SA, Mav D, Gu H, Djukovic D, Shah R, Merrick BA, Raftery D, Wade PA.

Cell Rep. 2018 Jan 16;22(3):624-637. doi: 10.1016/j.celrep.2017.12.071.

14.

Base-Resolution Analysis of DNA Methylation Patterns Downstream of Dnmt3a in Mouse Naïve B Cells.

Duncan CG, Kondilis-Mangum HD, Grimm SA, Bushel PR, Chrysovergis K, Roberts JD, Tyson FL, Merrick BA, Wade PA.

G3 (Bethesda). 2018 Mar 2;8(3):805-813. doi: 10.1534/g3.117.300446.

15.

Role of ERα in Mediating Female Uterine Transcriptional Responses to IGF1.

Hewitt SC, Winuthayanon W, Lierz SL, Hamilton KJ, Donoghue LJ, Ramsey JT, Grimm SA, Arao Y, Korach KS.

Endocrinology. 2017 Aug 1;158(8):2427-2435. doi: 10.1210/en.2017-00349.

16.

The novel p53 target TNFAIP8 variant 2 is increased in cancer and offsets p53-dependent tumor suppression.

Lowe JM, Nguyen TA, Grimm SA, Gabor KA, Peddada SD, Li L, Anderson CW, Resnick MA, Menendez D, Fessler MB.

Cell Death Differ. 2017 Jan;24(1):181-191. doi: 10.1038/cdd.2016.130. Epub 2016 Nov 11.

17.

The Impact of Environmental and Endogenous Damage on Somatic Mutation Load in Human Skin Fibroblasts.

Saini N, Roberts SA, Klimczak LJ, Chan K, Grimm SA, Dai S, Fargo DC, Boyer JC, Kaufmann WK, Taylor JA, Lee E, Cortes-Ciriano I, Park PJ, Schurman SH, Malc EP, Mieczkowski PA, Gordenin DA.

PLoS Genet. 2016 Oct 27;12(10):e1006385. doi: 10.1371/journal.pgen.1006385. eCollection 2016 Oct.

18.

A phase II trial evaluating the effects and intra-tumoral penetration of bortezomib in patients with recurrent malignant gliomas.

Raizer JJ, Chandler JP, Ferrarese R, Grimm SA, Levy RM, Muro K, Rosenow J, Helenowski I, Rademaker A, Paton M, Bredel M.

J Neurooncol. 2016 Aug;129(1):139-46. doi: 10.1007/s11060-016-2156-3. Epub 2016 Jun 14.

PMID:
27300524
19.

Anaplastic astrocytoma.

Grimm SA, Chamberlain MC.

CNS Oncol. 2016 Jul;5(3):145-57. doi: 10.2217/cns-2016-0002. Epub 2016 May 27. Review.

20.

GATA3-dependent cellular reprogramming requires activation-domain dependent recruitment of a chromatin remodeler.

Takaku M, Grimm SA, Shimbo T, Perera L, Menafra R, Stunnenberg HG, Archer TK, Machida S, Kurumizaka H, Wade PA.

Genome Biol. 2016 Feb 27;17:36. doi: 10.1186/s13059-016-0897-0.

21.

GATA3 in Breast Cancer: Tumor Suppressor or Oncogene?

Takaku M, Grimm SA, Wade PA.

Gene Expr. 2015;16(4):163-8. doi: 10.3727/105221615X14399878166113. Review.

22.

Bevacizumab and other novel therapies for recurrent oligodendroglial tumors.

Grimm SA, Chamberlain MC.

CNS Oncol. 2015;4(5):333-9. doi: 10.2217/cns.15.27. Epub 2015 Oct 28. Review.

23.

A randomized phase I/II study of ABT-888 in combination with temozolomide in recurrent temozolomide resistant glioblastoma: an NRG oncology RTOG group study.

Robins HI, Zhang P, Gilbert MR, Chakravarti A, de Groot JF, Grimm SA, Wang F, Lieberman FS, Krauze A, Trotti AM, Mohile N, Kee AY, Colman H, Cavaliere R, Kesari S, Chmura SJ, Mehta M.

J Neurooncol. 2016 Jan;126(2):309-16. doi: 10.1007/s11060-015-1966-z. Epub 2015 Oct 27.

24.

LIN28A Modulates Splicing and Gene Expression Programs in Breast Cancer Cells.

Yang J, Bennett BD, Luo S, Inoue K, Grimm SA, Schroth GP, Bushel PR, Kinyamu HK, Archer TK.

Mol Cell Biol. 2015 Sep;35(18):3225-43. doi: 10.1128/MCB.00426-15. Epub 2015 Jul 6.

25.

Financial burden experienced by patients undergoing treatment for malignant gliomas.

Kumthekar P, Stell BV, Jacobs DI, Helenowski IB, Rademaker AW, Grimm SA, Bennett CL, Raizer JJ.

Neurooncol Pract. 2014 Jun;1(2):71-76. Epub 2014 May 5.

26.

Concordance of patient and caregiver reports in evaluating quality of life in patients with malignant gliomas and an assessment of caregiver burden.

Jacobs DI, Kumthekar P, Stell BV, Grimm SA, Rademaker AW, Rice L, Chandler JP, Muro K, Marymont M, Helenowski IB, Wagner LI, Raizer JJ.

Neurooncol Pract. 2014 Jun;1(2):47-54. Epub 2014 May 5.

27.

Phase II study of panobinostat in combination with bevacizumab for recurrent glioblastoma and anaplastic glioma.

Lee EQ, Reardon DA, Schiff D, Drappatz J, Muzikansky A, Grimm SA, Norden AD, Nayak L, Beroukhim R, Rinne ML, Chi AS, Batchelor TT, Hempfling K, McCluskey C, Smith KH, Gaffey SC, Wrigley B, Ligon KL, Raizer JJ, Wen PY.

Neuro Oncol. 2015 Jun;17(6):862-7. doi: 10.1093/neuonc/nou350. Epub 2015 Jan 7. Erratum in: Neuro Oncol. 2015 Dec;17(12):1650.

28.

Economics of Malignant Gliomas: A Critical Review.

Raizer JJ, Fitzner KA, Jacobs DI, Bennett CL, Liebling DB, Luu TH, Trifilio SM, Grimm SA, Fisher MJ, Haleem MS, Ray PS, McKoy JM, DeBoer R, Tulas KM, Deeb M, McKoy JM.

J Oncol Pract. 2015 Jan;11(1):e59-65. doi: 10.1200/JOP.2012.000560. Epub 2014 Dec 2.

29.

Breast tumor specific mutation in GATA3 affects physiological mechanisms regulating transcription factor turnover.

Adomas AB, Grimm SA, Malone C, Takaku M, Sims JK, Wade PA.

BMC Cancer. 2014 Apr 22;14:278. doi: 10.1186/1471-2407-14-278.

30.

Novel DNA motif binding activity observed in vivo with an estrogen receptor α mutant mouse.

Hewitt SC, Li L, Grimm SA, Winuthayanon W, Hamilton KJ, Pockette B, Rubel CA, Pedersen LC, Fargo D, Lanz RB, DeMayo FJ, Schütz G, Korach KS.

Mol Endocrinol. 2014 Jun;28(6):899-911. doi: 10.1210/me.2014-1051. Epub 2014 Apr 8.

31.

Obesity, rather than diet, drives epigenomic alterations in colonic epithelium resembling cancer progression.

Li R, Grimm SA, Chrysovergis K, Kosak J, Wang X, Du Y, Burkholder A, Janardhan K, Mav D, Shah R, Eling TE, Wade PA.

Cell Metab. 2014 Apr 1;19(4):702-11. doi: 10.1016/j.cmet.2014.03.012.

32.

Diffusion abnormalities of the corpus callosum in patients receiving bevacizumab for malignant brain tumors: suspected treatment toxicity.

Futterer SF, Nemeth AJ, Grimm SA, Ragin AB, Chandler JP, Muro K, Marymont MH, Raizer JJ.

J Neurooncol. 2014 May;118(1):147-53. doi: 10.1007/s11060-014-1409-2. Epub 2014 Feb 28.

PMID:
24574050
33.

Fine-tuning of epigenetic regulation with respect to promoter CpG content in a cell type-specific manner.

Li R, Mav D, Grimm SA, Jothi R, Shah R, Wade PA.

Epigenetics. 2014 May;9(5):747-59. doi: 10.4161/epi.28075. Epub 2014 Feb 12.

34.

A phase II trial of PTK787/ZK 222584 in recurrent or progressive radiation and surgery refractory meningiomas.

Raizer JJ, Grimm SA, Rademaker A, Chandler JP, Muro K, Helenowski I, Rice L, McCarthy K, Johnston SK, Mrugala MM, Chamberlain M.

J Neurooncol. 2014 Mar;117(1):93-101. doi: 10.1007/s11060-014-1358-9. Epub 2014 Jan 22.

PMID:
24449400
35.

MBD3 localizes at promoters, gene bodies and enhancers of active genes.

Shimbo T, Du Y, Grimm SA, Dhasarathy A, Mav D, Shah RR, Shi H, Wade PA.

PLoS Genet. 2013;9(12):e1004028. doi: 10.1371/journal.pgen.1004028. Epub 2013 Dec 26.

36.

DNA methylation profiling in human B cells reveals immune regulatory elements and epigenetic plasticity at Alu elements during B-cell activation.

Lai AY, Mav D, Shah R, Grimm SA, Phadke D, Hatzi K, Melnick A, Geigerman C, Sobol SE, Jaye DL, Wade PA.

Genome Res. 2013 Dec;23(12):2030-41. doi: 10.1101/gr.155473.113. Epub 2013 Sep 6.

37.

An APOBEC cytidine deaminase mutagenesis pattern is widespread in human cancers.

Roberts SA, Lawrence MS, Klimczak LJ, Grimm SA, Fargo D, Stojanov P, Kiezun A, Kryukov GV, Carter SL, Saksena G, Harris S, Shah RR, Resnick MA, Getz G, Gordenin DA.

Nat Genet. 2013 Sep;45(9):970-6. doi: 10.1038/ng.2702. Epub 2013 Jul 14.

38.

Anaplastic astrocytoma.

Grimm SA, Pfiffner TJ.

Curr Treat Options Neurol. 2013 Jun;15(3):302-15. doi: 10.1007/s11940-013-0228-7.

PMID:
23543397
39.

Brainstem glioma: a review.

Grimm SA, Chamberlain MC.

Curr Neurol Neurosci Rep. 2013 May;13(5):346. doi: 10.1007/s11910-013-0346-3. Review.

PMID:
23512689
40.

Pharmacokinetics and efficacy of pemetrexed in patients with brain or leptomeningeal metastases.

Kumthekar P, Grimm SA, Avram MJ, Kaklamani V, Helenowski I, Rademaker A, Cianfrocca M, Gradishar W, Patel J, Mulcahy M, McCarthy K, Raizer JJ.

J Neurooncol. 2013 Apr;112(2):247-55. doi: 10.1007/s11060-013-1055-0. Epub 2013 Jan 25.

PMID:
23354655
41.

Outcome of discontinuing bevacizumab prior to malignant glioma progression.

Sherman WJ, Raizer JJ, Grimm SA.

J Neurooncol. 2013 Jan;111(1):87-9. doi: 10.1007/s11060-012-0985-2. Epub 2012 Oct 12. No abstract available.

PMID:
23065093
42.

State of the art and perspectives in the treatment of glioblastoma.

Grimm SA, Chamberlain MC.

CNS Oncol. 2012 Sep;1(1):49-70. doi: 10.2217/cns.12.5. Review.

43.

Phase I study of arsenic trioxide and temozolomide in combination with radiation therapy in patients with malignant gliomas.

Grimm SA, Marymont M, Chandler JP, Muro K, Newman SB, Levy RM, Jovanovic B, McCarthy K, Raizer JJ.

J Neurooncol. 2012 Nov;110(2):237-43. doi: 10.1007/s11060-012-0957-6. Epub 2012 Aug 9.

PMID:
22875709
44.

Research resource: whole-genome estrogen receptor α binding in mouse uterine tissue revealed by ChIP-seq.

Hewitt SC, Li L, Grimm SA, Chen Y, Liu L, Li Y, Bushel PR, Fargo D, Korach KS.

Mol Endocrinol. 2012 May;26(5):887-98. doi: 10.1210/me.2011-1311. Epub 2012 Mar 22.

45.

Pemetrexed in the treatment of relapsed/refractory primary central nervous system lymphoma.

Raizer JJ, Rademaker A, Evens AM, Rice L, Schwartz M, Chandler JP, Getch CC, Tellez C, Grimm SA.

Cancer. 2012 Aug 1;118(15):3743-8. doi: 10.1002/cncr.26709. Epub 2011 Dec 16.

46.

Treatment of brain metastases: chemotherapy.

Grimm SA.

Curr Oncol Rep. 2012 Feb;14(1):85-90. doi: 10.1007/s11912-011-0211-y. Review.

PMID:
22161303
47.

Phase I study of panobinostat in combination with bevacizumab for recurrent high-grade glioma.

Drappatz J, Lee EQ, Hammond S, Grimm SA, Norden AD, Beroukhim R, Gerard M, Schiff D, Chi AS, Batchelor TT, Doherty LM, Ciampa AS, Lafrankie DC, Ruland S, Snodgrass SM, Raizer JJ, Wen PY.

J Neurooncol. 2012 Mar;107(1):133-8. doi: 10.1007/s11060-011-0717-z. Epub 2011 Oct 8.

PMID:
21984064
48.

Metastatic glioblastoma: case presentations and a review of the literature.

Kalokhe G, Grimm SA, Chandler JP, Helenowski I, Rademaker A, Raizer JJ.

J Neurooncol. 2012 Mar;107(1):21-7. doi: 10.1007/s11060-011-0731-1. Epub 2011 Oct 2. Review.

PMID:
21964740
49.

MapSplice: accurate mapping of RNA-seq reads for splice junction discovery.

Wang K, Singh D, Zeng Z, Coleman SJ, Huang Y, Savich GL, He X, Mieczkowski P, Grimm SA, Perou CM, MacLeod JN, Chiang DY, Prins JF, Liu J.

Nucleic Acids Res. 2010 Oct;38(18):e178. doi: 10.1093/nar/gkq622. Epub 2010 Aug 27.

50.

Glioblastoma: a method for predicting response to antiangiogenic chemotherapy by using MR perfusion imaging--pilot study.

Sawlani RN, Raizer J, Horowitz SW, Shin W, Grimm SA, Chandler JP, Levy R, Getch C, Carroll TJ.

Radiology. 2010 May;255(2):622-8. doi: 10.1148/radiol.10091341.

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