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Items: 47

1.

Rational Design of Fluorogenic and Spontaneously Blinking Labels for Super-Resolution Imaging.

Zheng Q, Ayala AX, Chung I, Weigel AV, Ranjan A, Falco N, Grimm JB, Tkachuk AN, Wu C, Lippincott-Schwartz J, Singer RH, Lavis LD.

ACS Cent Sci. 2019 Sep 25;5(9):1602-1613. doi: 10.1021/acscentsci.9b00676. Epub 2019 Sep 5.

2.

Bright and photostable chemigenetic indicators for extended in vivo voltage imaging.

Abdelfattah AS, Kawashima T, Singh A, Novak O, Liu H, Shuai Y, Huang YC, Campagnola L, Seeman SC, Yu J, Zheng J, Grimm JB, Patel R, Friedrich J, Mensh BD, Paninski L, Macklin JJ, Murphy GJ, Podgorski K, Lin BJ, Chen TW, Turner GC, Liu Z, Koyama M, Svoboda K, Ahrens MB, Lavis LD, Schreiter ER.

Science. 2019 Aug 16;365(6454):699-704. doi: 10.1126/science.aav6416. Epub 2019 Aug 1.

PMID:
31371562
3.

Bioorthogonal labeling with tetrazine-dyes for super-resolution microscopy.

Beliu G, Kurz AJ, Kuhlemann AC, Behringer-Pliess L, Meub M, Wolf N, Seibel J, Shi ZD, Schnermann M, Grimm JB, Lavis LD, Doose S, Sauer M.

Commun Biol. 2019 Jul 19;2:261. doi: 10.1038/s42003-019-0518-z. eCollection 2019.

4.

Multi-Color Single-Molecule Imaging Uncovers Extensive Heterogeneity in mRNA Decoding.

Boersma S, Khuperkar D, Verhagen BMP, Sonneveld S, Grimm JB, Lavis LD, Tanenbaum ME.

Cell. 2019 Jul 11;178(2):458-472.e19. doi: 10.1016/j.cell.2019.05.001. Epub 2019 Jun 6.

5.

Whole-Cell, 3D, and Multicolor STED Imaging with Exchangeable Fluorophores.

Spahn C, Grimm JB, Lavis LD, Lampe M, Heilemann M.

Nano Lett. 2019 Jan 9;19(1):500-505. doi: 10.1021/acs.nanolett.8b04385. Epub 2018 Dec 14.

PMID:
30525682
6.

A toolbox for multiplexed super-resolution imaging of the E. coli nucleoid and membrane using novel PAINT labels.

Spahn CK, Glaesmann M, Grimm JB, Ayala AX, Lavis LD, Heilemann M.

Sci Rep. 2018 Oct 3;8(1):14768. doi: 10.1038/s41598-018-33052-3.

7.

Cell-Specific Chemical Delivery Using a Selective Nitroreductase-Nitroaryl Pair.

Gruber TD, Krishnamurthy C, Grimm JB, Tadross MR, Wysocki LM, Gartner ZJ, Lavis LD.

ACS Chem Biol. 2018 Oct 19;13(10):2888-2896. doi: 10.1021/acschembio.8b00524. Epub 2018 Aug 29.

8.

Optimization of fluorophores for chemical tagging and immunohistochemistry of Drosophila neurons.

Meissner GW, Grimm JB, Johnston RM, Sutcliffe B, Ng J, Jefferis GSXE, Cachero S, Lavis LD, Malkesman O.

PLoS One. 2018 Aug 15;13(8):e0200759. doi: 10.1371/journal.pone.0200759. eCollection 2018.

9.

Robust model-based analysis of single-particle tracking experiments with Spot-On.

Hansen AS, Woringer M, Grimm JB, Lavis LD, Tjian R, Darzacq X.

Elife. 2018 Jan 4;7. pii: e33125. doi: 10.7554/eLife.33125.

10.

Visualizing long-term single-molecule dynamics in vivo by stochastic protein labeling.

Liu H, Dong P, Ioannou MS, Li L, Shea J, Pasolli HA, Grimm JB, Rivlin PK, Lavis LD, Koyama M, Liu Z.

Proc Natl Acad Sci U S A. 2018 Jan 9;115(2):343-348. doi: 10.1073/pnas.1713895115. Epub 2017 Dec 28.

11.

Semisynthetic fluorescent pH sensors for imaging exocytosis and endocytosis.

Martineau M, Somasundaram A, Grimm JB, Gruber TD, Choquet D, Taraska JW, Lavis LD, Perrais D.

Nat Commun. 2017 Nov 10;8(1):1412. doi: 10.1038/s41467-017-01752-5.

12.

General Synthetic Method for Si-Fluoresceins and Si-Rhodamines.

Grimm JB, Brown TA, Tkachuk AN, Lavis LD.

ACS Cent Sci. 2017 Sep 27;3(9):975-985. doi: 10.1021/acscentsci.7b00247. Epub 2017 Aug 9.

13.

Cohesin Can Remain Associated with Chromosomes during DNA Replication.

Rhodes JDP, Haarhuis JHI, Grimm JB, Rowland BD, Lavis LD, Nasmyth KA.

Cell Rep. 2017 Sep 19;20(12):2749-2755. doi: 10.1016/j.celrep.2017.08.092.

14.

Synthesis of Janelia Fluor HaloTag and SNAP-Tag Ligands and Their Use in Cellular Imaging Experiments.

Grimm JB, Brown TA, English BP, Lionnet T, Lavis LD.

Methods Mol Biol. 2017;1663:179-188. doi: 10.1007/978-1-4939-7265-4_15.

PMID:
28924668
15.

A general method to fine-tune fluorophores for live-cell and in vivo imaging.

Grimm JB, Muthusamy AK, Liang Y, Brown TA, Lemon WC, Patel R, Lu R, Macklin JJ, Keller PJ, Ji N, Lavis LD.

Nat Methods. 2017 Oct;14(10):987-994. doi: 10.1038/nmeth.4403. Epub 2017 Sep 4.

16.

Desensitized D2 autoreceptors are resistant to trafficking.

Robinson BG, Bunzow JR, Grimm JB, Lavis LD, Dudman JT, Brown J, Neve KA, Williams JT.

Sci Rep. 2017 Jun 29;7(1):4379. doi: 10.1038/s41598-017-04728-z.

17.

Quantifying transcription factor binding dynamics at the single-molecule level in live cells.

Presman DM, Ball DA, Paakinaho V, Grimm JB, Lavis LD, Karpova TS, Hager GL.

Methods. 2017 Jul 1;123:76-88. doi: 10.1016/j.ymeth.2017.03.014. Epub 2017 Mar 15.

18.

Glutamate-induced RNA localization and translation in neurons.

Yoon YJ, Wu B, Buxbaum AR, Das S, Tsai A, English BP, Grimm JB, Lavis LD, Singer RH.

Proc Natl Acad Sci U S A. 2016 Nov 1;113(44):E6877-E6886. Epub 2016 Oct 17.

19.

Rapid dynamics of general transcription factor TFIIB binding during preinitiation complex assembly revealed by single-molecule analysis.

Zhang Z, English BP, Grimm JB, Kazane SA, Hu W, Tsai A, Inouye C, You C, Piehler J, Schultz PG, Lavis LD, Revyakin A, Tjian R.

Genes Dev. 2016 Sep 15;30(18):2106-2118.

20.

Bright photoactivatable fluorophores for single-molecule imaging.

Grimm JB, English BP, Choi H, Muthusamy AK, Mehl BP, Dong P, Brown TA, Lippincott-Schwartz J, Liu Z, Lionnet T, Lavis LD.

Nat Methods. 2016 Dec;13(12):985-988. doi: 10.1038/nmeth.4034. Epub 2016 Oct 24.

PMID:
27776112
21.

Live-cell single-molecule tracking reveals co-recognition of H3K27me3 and DNA targets polycomb Cbx7-PRC1 to chromatin.

Zhen CY, Tatavosian R, Huynh TN, Duc HN, Das R, Kokotovic M, Grimm JB, Lavis LD, Lee J, Mejia FJ, Li Y, Yao T, Ren X.

Elife. 2016 Oct 10;5. pii: e17667. doi: 10.7554/eLife.17667.

22.

Real-time imaging of Huntingtin aggregates diverting target search and gene transcription.

Li L, Liu H, Dong P, Li D, Legant WR, Grimm JB, Lavis LD, Betzig E, Tjian R, Liu Z.

Elife. 2016 Aug 3;5. pii: e17056. doi: 10.7554/eLife.17056.

23.

Real-time quantification of single RNA translation dynamics in living cells.

Morisaki T, Lyon K, DeLuca KF, DeLuca JG, English BP, Zhang Z, Lavis LD, Grimm JB, Viswanathan S, Looger LL, Lionnet T, Stasevich TJ.

Science. 2016 Jun 17;352(6292):1425-9. doi: 10.1126/science.aaf0899. Epub 2016 May 5.

24.

Design and Synthesis of a Calcium-Sensitive Photocage.

Heckman LM, Grimm JB, Schreiter ER, Kim C, Verdecia MA, Shields BC, Lavis LD.

Angew Chem Int Ed Engl. 2016 Jul 11;55(29):8363-6. doi: 10.1002/anie.201602941. Epub 2016 May 24.

25.

RNA Polymerase II cluster dynamics predict mRNA output in living cells.

Cho WK, Jayanth N, English BP, Inoue T, Andrews JO, Conway W, Grimm JB, Spille JH, Lavis LD, Lionnet T, Cisse II.

Elife. 2016 May 3;5. pii: e13617. doi: 10.7554/eLife.13617.

26.

Steroid Receptors Reprogram FoxA1 Occupancy through Dynamic Chromatin Transitions.

Swinstead EE, Miranda TB, Paakinaho V, Baek S, Goldstein I, Hawkins M, Karpova TS, Ball D, Mazza D, Lavis LD, Grimm JB, Morisaki T, Grøntved L, Presman DM, Hager GL.

Cell. 2016 Apr 21;165(3):593-605. doi: 10.1016/j.cell.2016.02.067. Epub 2016 Apr 7.

27.

High-density three-dimensional localization microscopy across large volumes.

Legant WR, Shao L, Grimm JB, Brown TA, Milkie DE, Avants BB, Lavis LD, Betzig E.

Nat Methods. 2016 Apr;13(4):359-65. doi: 10.1038/nmeth.3797. Epub 2016 Mar 7.

28.

Synthesis of a Far-Red Photoactivatable Silicon-Containing Rhodamine for Super-Resolution Microscopy.

Grimm JB, Klein T, Kopek BG, Shtengel G, Hess HF, Sauer M, Lavis LD.

Angew Chem Int Ed Engl. 2016 Jan 26;55(5):1723-7. doi: 10.1002/anie.201509649. Epub 2015 Dec 11.

29.

Virginia Orange: A Versatile, Red-Shifted Fluorescein Scaffold for Single- and Dual-Input Fluorogenic Probes.

Grimm JB, Gruber TD, Ortiz G, Brown TA, Lavis LD.

Bioconjug Chem. 2016 Feb 17;27(2):474-80. doi: 10.1021/acs.bioconjchem.5b00566. Epub 2015 Dec 22.

30.

A general method to improve fluorophores for live-cell and single-molecule microscopy.

Grimm JB, English BP, Chen J, Slaughter JP, Zhang Z, Revyakin A, Patel R, Macklin JJ, Normanno D, Singer RH, Lionnet T, Lavis LD.

Nat Methods. 2015 Mar;12(3):244-50, 3 p following 250. doi: 10.1038/nmeth.3256. Epub 2015 Jan 19.

31.

3D imaging of Sox2 enhancer clusters in embryonic stem cells.

Liu Z, Legant WR, Chen BC, Li L, Grimm JB, Lavis LD, Betzig E, Tjian R.

Elife. 2014 Dec 24;3:e04236. doi: 10.7554/eLife.04236.

32.

Single-molecule tracking of the transcription cycle by sub-second RNA detection.

Zhang Z, Revyakin A, Grimm JB, Lavis LD, Tjian R.

Elife. 2014;3:e01775. doi: 10.7554/eLife.01775. Epub 2014 Jan 28.

33.

Correlative photoactivated localization and scanning electron microscopy.

Kopek BG, Shtengel G, Grimm JB, Clayton DA, Hess HF.

PLoS One. 2013 Oct 25;8(10):e77209. doi: 10.1371/journal.pone.0077209. eCollection 2013.

34.

Carbofluoresceins and carborhodamines as scaffolds for high-contrast fluorogenic probes.

Grimm JB, Sung AJ, Legant WR, Hulamm P, Matlosz SM, Betzig E, Lavis LD.

ACS Chem Biol. 2013;8(6):1303-10. doi: 10.1021/cb4000822. Epub 2013 Apr 24.

35.

The chemistry of small-molecule fluorogenic probes.

Grimm JB, Heckman LM, Lavis LD.

Prog Mol Biol Transl Sci. 2013;113:1-34. doi: 10.1016/B978-0-12-386932-6.00001-6. Review.

PMID:
23244787
36.

Synthesis of rhodamines from fluoresceins using Pd-catalyzed C-N cross-coupling.

Grimm JB, Lavis LD.

Org Lett. 2011 Dec 16;13(24):6354-7. doi: 10.1021/ol202618t. Epub 2011 Nov 17.

37.

Facile and general synthesis of photoactivatable xanthene dyes.

Wysocki LM, Grimm JB, Tkachuk AN, Brown TA, Betzig E, Lavis LD.

Angew Chem Int Ed Engl. 2011 Nov 18;50(47):11206-9. doi: 10.1002/anie.201104571. Epub 2011 Sep 26. No abstract available.

38.

A divergent approach to the synthesis of 3-substituted-2-pyrazolines: Suzuki cross-coupling of 3-sulfonyloxy-2-pyrazolines.

Grimm JB, Wilson KJ, Witter DJ.

J Org Chem. 2009 Aug 21;74(16):6390-3. doi: 10.1021/jo9011859.

PMID:
20560575
39.

Exploring the pharmacokinetic properties of phosphorus-containing selective HDAC 1 and 2 inhibitors (SHI-1:2).

Heidebrecht RW Jr, Chenard M, Close J, Dahlberg WK, Fleming J, Grimm JB, Hamill JE, Harsch A, Haines BB, Hughes B, Kral AM, Middleton RE, Mushti C, Ozerova N, Szewczak AA, Wang H, Wilson K, Witter DJ, Secrist JP, Miller TA.

Bioorg Med Chem Lett. 2009 Apr 1;19(7):2053-8. doi: 10.1016/j.bmcl.2009.02.009. Epub 2009 Feb 8.

PMID:
19268585
40.

Phenylglycine and phenylalanine derivatives as potent and selective HDAC1 inhibitors (SHI-1).

Wilson KJ, Witter DJ, Grimm JB, Siliphaivanh P, Otte KM, Kral AM, Fleming JC, Harsch A, Hamill JE, Cruz JC, Chenard M, Szewczak AA, Middleton RE, Hughes BL, Dahlberg WK, Secrist JP, Miller TA.

Bioorg Med Chem Lett. 2008 Mar 15;18(6):1859-63. doi: 10.1016/j.bmcl.2008.02.012. Epub 2008 Feb 10.

PMID:
18304810
41.

Absence of the Thorpe-Ingold Effect by gem-Diphenyl Groups in Ring-Closing Enyne Metathesis.

Kim YJ, Grimm JB, Lee D.

Tetrahedron Lett. 2007 Nov 5;48(45):7961-7964.

42.

A new strategy for the synthesis of benzylic sulfonamides: palladium-catalyzed arylation and sulfonamide metathesis.

Grimm JB, Katcher MH, Witter DJ, Northrup AB.

J Org Chem. 2007 Oct 12;72(21):8135-8. Epub 2007 Sep 20.

PMID:
17880242
43.

Determination of glomerular filtration rate in dogs using contrast-enhanced computed tomography.

O'Dell-Anderson KJ, Twardock R, Grimm JB, Grimm KA, Constable PD.

Vet Radiol Ultrasound. 2006 Mar-Apr;47(2):127-35.

PMID:
16553143
44.
45.

What is your diagnosis? A pedunculated heterogeneous mineral opacity structure is evident ventral to the third premolar on the left mandible.

Olds AM, Stewart AA, Grimm JB.

J Am Vet Med Assoc. 2004 Apr 1;224(7):1073-4. No abstract available.

PMID:
15074850
46.

Design, synthesis, and development of novel caprolactam anticonvulsants.

Grimm JB, Stables JP, Brown ML.

Bioorg Med Chem. 2003 Sep 1;11(18):4133-41.

PMID:
12927875
47.

The effect of a combination of medetomidine-butorphanol and medetomidine, butorphanol, atropine on glomerular filtration rate in dogs.

Grimm JB, Grimm KA, Kneller SK, Tranquilli WJ, Crochik SS, Bischoff MG, Podolski JL.

Vet Radiol Ultrasound. 2001 Sep-Oct;42(5):458-62.

PMID:
11678570

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