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Start Selective and Rigidify: The Discovery Path toward a Next Generation of EGFR Tyrosine Kinase Inhibitors.

Engelhardt H, Böse D, Petronczki M, Scharn D, Bader G, Baum A, Bergner A, Chong E, Döbel S, Egger G, Engelhardt C, Ettmayer P, Fuchs JE, Gerstberger T, Gonnella N, Grimm A, Grondal E, Haddad N, Hopfgartner B, Kousek R, Krawiec M, Kriz M, Lamarre L, Leung J, Mayer M, Patel ND, Simov BP, Reeves JT, Schnitzer R, Schrenk A, Sharps B, Solca F, Stadtmüller H, Tan Z, Wunberg T, Zoephel A, McConnell DB.

J Med Chem. 2019 Nov 13. doi: 10.1021/acs.jmedchem.9b01169. [Epub ahead of print]


Pioneer interneurons instruct bilaterality in the Drosophila olfactory sensory map.

Kaur R, Surala M, Hoger S, Grössmann N, Grimm A, Timaeus L, Kallina W, Hummel T.

Sci Adv. 2019 Oct 23;5(10):eaaw5537. doi: 10.1126/sciadv.aaw5537. eCollection 2019 Oct.


An efficient method for the plating of haploid and diploid Emiliania huxleyi on solid medium.

Skeffington AW, Grimm A, Schönefeld S, Petersen K, Scheffel A.

J Phycol. 2019 Oct 28. doi: 10.1111/jpy.12942. [Epub ahead of print]


Hospital volume and mortality in liver resections for colorectal metastasis using population-based administrative data.

Hunger R, Mantke A, Herrmann C, Grimm AL, Ludwig J, Mantke R.

J Hepatobiliary Pancreat Sci. 2019 Sep 28. doi: 10.1002/jhbp.680. [Epub ahead of print]


Artefact and ablation performance of an MR-conditional high-power microwave system in bovine livers: an ex vivo study.

Grimm A, Winkelmann M, Weiß J, Gohla G, Blumenstock G, Nikolaou K, Clasen S, Hoffmann R.

Eur Radiol Exp. 2019 Sep 23;3(1):39. doi: 10.1186/s41747-019-0115-4.


Mitochondria modulatory effects of new TSPO ligands in a cellular model of tauopathies.

Grimm A, Lejri I, Hallé F, Schmitt M, Götz J, Bihel F, Eckert A.

J Neuroendocrinol. 2019 Sep 19:e12796. doi: 10.1111/jne.12796. [Epub ahead of print]


Safety and Efficacy of Teduglutide in Pediatric Patients With Intestinal Failure due to Short Bowel Syndrome: A 24-Week, Phase III Study.

Kocoshis SA, Merritt RJ, Hill S, Protheroe S, Carter BA, Horslen S, Hu S, Kaufman SS, Mercer DF, Pakarinen MP, Venick RS, Wales PW, Grimm AA.

JPEN J Parenter Enteral Nutr. 2019 Sep 8. doi: 10.1002/jpen.1690. [Epub ahead of print]


Visitors to a Tropical Marine Beach Show Evidence of Immunoconversions to Multiple Waterborne Pathogens.

Simmons KJ, Eason TN, Curioso CL, Griffin SM, Ramudit MKD, Oshima KH, Sams EA, Wade TJ, Grimm A, Dufour A, Augustine SAJ.

Front Public Health. 2019 Aug 19;7:231. doi: 10.3389/fpubh.2019.00231. eCollection 2019.


De novo variants in SLC12A6 cause sporadic early-onset progressive sensorimotor neuropathy.

Park J, Flores BR, Scherer K, Kuepper H, Rossi M, Rupprich K, Rautenberg M, Deininger N, Weichselbaum A, Grimm A, Sturm M, Grasshoff U, Delpire E, Haack TB.

J Med Genet. 2019 Aug 22. pii: jmedgenet-2019-106273. doi: 10.1136/jmedgenet-2019-106273. [Epub ahead of print]


Extended evaluation of the efficacy of a proactive forced oscillation technique-based auto-CPAP algorithm.

Herkenrath SD, Treml M, Anduleit N, Richter K, Pietzke-Calcagnile A, Schwaibold M, Schäfer R, Alshut R, Grimm A, Hagmeyer L, Randerath WJ.

Sleep Breath. 2019 Aug 6. doi: 10.1007/s11325-019-01901-8. [Epub ahead of print]


Guidelines for neuromuscular ultrasound training.

Tawfik EA, Cartwright MS, Grimm A, Boon AJ, Kerasnoudis A, Preston DC, Wilder-Smith E, Axer H, Hobson-Webb LD, van Alfen N, Crump N, Shahrizaila N, Inkpen P, Mandeville R, Sakamuri S, Shook SJ, Shin S, Walker FO.

Muscle Nerve. 2019 Oct;60(4):361-366. doi: 10.1002/mus.26642. Epub 2019 Aug 12.


TSPO Ligands Boost Mitochondrial Function and Pregnenolone Synthesis.

Lejri I, Grimm A, Hallé F, Abarghaz M, Klein C, Maitre M, Schmitt M, Bourguignon JJ, Mensah-Nyagan AG, Bihel F, Eckert A.

J Alzheimers Dis. 2019 Jun 24. doi: 10.3233/JAD-190127. [Epub ahead of print]


Nerve Ultrasonography as an Additive Tool to Clinical Examination and Electrodiagnostics in Sporadic Mononeuritis - Imaging is the Key.

Winter N, Dammeier N, Schäffer E, Bornemann A, Stahl JH, Herlan S, Schuhmann MU, Grimm A.

Ultraschall Med. 2019 Aug;40(4):465-472. doi: 10.1055/a-0919-4768. Epub 2019 Jun 25.


Mitochondria- and Oxidative Stress-Targeting Substances in Cognitive Decline-Related Disorders: From Molecular Mechanisms to Clinical Evidence.

Lejri I, Agapouda A, Grimm A, Eckert A.

Oxid Med Cell Longev. 2019 May 12;2019:9695412. doi: 10.1155/2019/9695412. eCollection 2019. Review.


Cooperation between Constitutive and Inducible Chemokines Enables T Cell Engraftment and Immune Attack in Solid Tumors.

Dangaj D, Bruand M, Grimm AJ, Ronet C, Barras D, Duttagupta PA, Lanitis E, Duraiswamy J, Tanyi JL, Benencia F, Conejo-Garcia J, Ramay HR, Montone KT, Powell DJ Jr, Gimotty PA, Facciabene A, Jackson DG, Weber JS, Rodig SJ, Hodi SF, Kandalaft LE, Irving M, Zhang L, Foukas P, Rusakiewicz S, Delorenzi M, Coukos G.

Cancer Cell. 2019 Jun 10;35(6):885-900.e10. doi: 10.1016/j.ccell.2019.05.004.


Median nerve dissection after brachial artery catheterization revealed by high-resolution ultrasound.

Stefanou MI, Schubert V, Ruschil C, Winter N, Schuhmann MU, Ziemann U, Grimm A.

Clin Neurophysiol. 2019 Jul;130(7):1081-1082. doi: 10.1016/j.clinph.2019.04.007. Epub 2019 Apr 18. No abstract available.


Feasibility of Dixon magnetic resonance imaging to quantify effects of physical training on muscle composition-A pilot study in young and healthy men.

Grimm A, Nickel MD, Chaudry O, Uder M, Jakob F, Kemmler W, Quick HH, Engelke K.

Eur J Radiol. 2019 May;114:160-166. doi: 10.1016/j.ejrad.2019.03.019. Epub 2019 Mar 26.


Gated Conditional Displacement Readout of Superconducting Qubits.

Touzard S, Kou A, Frattini NE, Sivak VV, Puri S, Grimm A, Frunzio L, Shankar S, Devoret MH.

Phys Rev Lett. 2019 Mar 1;122(8):080502. doi: 10.1103/PhysRevLett.122.080502.


MRI, CT and high resolution macro-anatomical images with cryosectioning of a Beagle brain: Creating the base of a multimodal imaging atlas.

Czeibert K, Baksa G, Grimm A, Nagy SA, Kubinyi E, Petneházy Ö.

PLoS One. 2019 Mar 7;14(3):e0213458. doi: 10.1371/journal.pone.0213458. eCollection 2019.


Differentiation Between Guillain-Barré Syndrome and Acute-Onset Chronic Inflammatory Demyelinating Polyradiculoneuritis-a Prospective Follow-up Study Using Ultrasound and Neurophysiological Measurements.

Grimm A, Oertl H, Auffenberg E, Schubert V, Ruschil C, Axer H, Winter N.

Neurotherapeutics. 2019 Jul;16(3):838-847. doi: 10.1007/s13311-019-00716-5.


A Comparison between 6-point Dixon MRI and MR Spectroscopy to Quantify Muscle Fat in the Thigh of Subjects with Sarcopenia.

Grimm A, Meyer H, Nickel MD, Nittka M, Raithel E, Chaudry O, Friedberger A, Uder M, Kemmler W, Engelke K, Quick HH.

J Frailty Aging. 2019;8(1):21-26. doi: 10.14283/jfa.2018.16.


The Age Factor Revisited: Timing in Acquisition Interacts With Age of Onset in Bilingual Acquisition.

Schulz P, Grimm A.

Front Psychol. 2019 Jan 14;9:2732. doi: 10.3389/fpsyg.2018.02732. eCollection 2018.


Link between the unfolded protein response and dysregulation of mitochondrial bioenergetics in Alzheimer's disease.

Poirier Y, Grimm A, Schmitt K, Eckert A.

Cell Mol Life Sci. 2019 Apr;76(7):1419-1431. doi: 10.1007/s00018-019-03009-4. Epub 2019 Jan 25.


Phenotypic spectrum of autosomal recessive retinitis pigmentosa without posterior column ataxia caused by mutations in the FLVCR1 gene.

Kuehlewein L, Schöls L, Llavona P, Grimm A, Biskup S, Zrenner E, Kohl S.

Graefes Arch Clin Exp Ophthalmol. 2019 Mar;257(3):629-638. doi: 10.1007/s00417-018-04233-7. Epub 2019 Jan 17.


Anchor Peptide-Mediated Surface Immobilization of a Grubbs-Hoveyda-Type Catalyst for Ring-Opening Metathesis Polymerization.

Grimm AR, Sauer DF, Mirzaei Garakani T, Rübsam K, Polen T, Davari MD, Jakob F, Schiffels J, Okuda J, Schwaneberg U.

Bioconjug Chem. 2019 Mar 20;30(3):714-720. doi: 10.1021/acs.bioconjchem.8b00874. Epub 2019 Jan 29.


Differential effects of learned associations with words and pseudowords on event-related brain potentials.

Kulke L, Bayer M, Grimm AM, Schacht A.

Neuropsychologia. 2019 Feb 18;124:182-191. doi: 10.1016/j.neuropsychologia.2018.12.012. Epub 2018 Dec 17.


Anaemia requiring red blood cell transfusion is associated with unfavourable 90-day survival in surgical patients with sepsis.

Kristof K, Büttner B, Grimm A, Mewes C, Schmack B, Popov AF, Ghadimi M, Beissbarth T, Hinz J, Bergmann I, Mansur A.

BMC Res Notes. 2018 Dec 11;11(1):879. doi: 10.1186/s13104-018-3988-z.


Nerve ultrasound characterizes AMN polyneuropathy as inhomogeneous and focal hypertrophic.

Rattay TW, Just J, Röben B, Hengel H, Schüle R, Synofzik M, Söhn AS, Winter N, Dammeier N, Schöls L, Grimm A.

Orphanet J Rare Dis. 2018 Nov 3;13(1):194. doi: 10.1186/s13023-018-0939-7.


Indications for neuromuscular ultrasound: Expert opinion and review of the literature.

Walker FO, Cartwright MS, Alter KE, Visser LH, Hobson-Webb LD, Padua L, Strakowski JA, Preston DC, Boon AJ, Axer H, van Alfen N, Tawfik EA, Wilder-Smith E, Yoon JS, Kim BJ, Breiner A, Bland JDP, Grimm A, Zaidman CM.

Clin Neurophysiol. 2018 Dec;129(12):2658-2679. doi: 10.1016/j.clinph.2018.09.013. Epub 2018 Sep 25. Review.


Local Oxidative Damage in the Soma and Dendrites Quarantines Neuronal Mitochondria at the Site of Insult.

Grimm A, Cummins N, Götz J.

iScience. 2018 Aug 31;6:114-127. doi: 10.1016/j.isci.2018.07.015. Epub 2018 Jul 23.


Repeatability of Dixon magnetic resonance imaging and magnetic resonance spectroscopy for quantitative muscle fat assessments in the thigh.

Grimm A, Meyer H, Nickel MD, Nittka M, Raithel E, Chaudry O, Friedberger A, Uder M, Kemmler W, Engelke K, Quick HH.

J Cachexia Sarcopenia Muscle. 2018 Dec;9(6):1093-1100. doi: 10.1002/jcsm.12343. Epub 2018 Sep 16.


Pigs that recover from porcine reproduction and respiratory syndrome virus infection develop cytotoxic CD4+CD8+ and CD4+CD8- T-cells that kill virus infected cells.

Chung CJ, Cha SH, Grimm AL, Ajithdoss D, Rzepka J, Chung G, Yu J, Davis WC, Ho CS.

PLoS One. 2018 Sep 6;13(9):e0203482. doi: 10.1371/journal.pone.0203482. eCollection 2018.


Donor Dopamine Does Not Affect Liver Graft Survival: Evidence of Safety From a Randomized Controlled Trial.

Benck U, Jung M, Krüger B, Grimm A, Weiss C, Yard BA, Lehner F, Kiessling A, Fischer L, Gallinat A, Kleespies A, Lorf T, Sucher R, Mönch C, Scherer MN, Rahmel A, Schemmer P, Krämer BK, Schnuelle P.

Liver Transpl. 2018 Oct;24(10):1336-1345. doi: 10.1002/lt.25301.


Chronisch immunvermittelte Neuropathien – Diagnostik und Therapie.

Grimm A, Axer H.

Fortschr Neurol Psychiatr. 2018 Jul;86(7):439-452. doi: 10.1055/s-0044-101831. Epub 2018 Jul 20. Review. German.


Not your average Saturday night palsy-High resolution nerve ultrasound resolves rare cause of wrist drop.

Heiling B, Waschke A, Ceanga M, Grimm A, Witte OW, Axer H.

Clin Neurol Neurosurg. 2018 Sep;172:160-161. doi: 10.1016/j.clineuro.2018.07.006. Epub 2018 Jul 9.


Analysis of blood supply in the hard palate and maxillary tuberosity-clinical implications for flap design and soft tissue graft harvesting (a human cadaver study).

Shahbazi A, Grimm A, Feigl G, Gerber G, Székely AD, Molnár B, Windisch P.

Clin Oral Investig. 2019 Mar;23(3):1153-1160. doi: 10.1007/s00784-018-2538-3. Epub 2018 Jul 1.


Evaluation of 2-point, 3-point, and 6-point Dixon magnetic resonance imaging with flexible echo timing for muscle fat quantification.

Grimm A, Meyer H, Nickel MD, Nittka M, Raithel E, Chaudry O, Friedberger A, Uder M, Kemmler W, Quick HH, Engelke K.

Eur J Radiol. 2018 Jun;103:57-64. doi: 10.1016/j.ejrad.2018.04.011. Epub 2018 Apr 12.


Mitochondria, Estrogen and Female Brain Aging.

Lejri I, Grimm A, Eckert A.

Front Aging Neurosci. 2018 Apr 27;10:124. doi: 10.3389/fnagi.2018.00124. eCollection 2018. Review.


Nerve ultrasound normal values - Readjustment of the ultrasound pattern sum score UPSS.

Grimm A, Axer H, Heiling B, Winter N.

Clin Neurophysiol. 2018 Jul;129(7):1403-1409. doi: 10.1016/j.clinph.2018.03.036. Epub 2018 Apr 13.


[Recognizing rare cardiac diseases by electrocardiogram].

Grimm W, Grimm A, Grimm K, Efimova E.

Internist (Berl). 2018 Jun;59(6):618-629. doi: 10.1007/s00108-018-0400-y. Review. German.


Circadian Control of DRP1 Activity Regulates Mitochondrial Dynamics and Bioenergetics.

Schmitt K, Grimm A, Dallmann R, Oettinghaus B, Restelli LM, Witzig M, Ishihara N, Mihara K, Ripperger JA, Albrecht U, Frank S, Brown SA, Eckert A.

Cell Metab. 2018 Mar 6;27(3):657-666.e5. doi: 10.1016/j.cmet.2018.01.011. Epub 2018 Feb 22.


Nerve Ultrasound Predicts Treatment Response in Chronic Inflammatory Demyelinating Polyradiculoneuropathy-a Prospective Follow-Up.

Härtig F, Ross M, Dammeier NM, Fedtke N, Heiling B, Axer H, Décard BF, Auffenberg E, Koch M, Rattay TW, Krumbholz M, Bornemann A, Lerche H, Winter N, Grimm A.

Neurotherapeutics. 2018 Apr;15(2):439-451. doi: 10.1007/s13311-018-0609-4.


Endovascular Treatment of Dural Arteriovenous Fistulas of the Anterior or Posterior Condylar Vein : A Cadaveric and Clinical Study and Literature Review.

Hellstern V, Aguilar-Pérez M, Schob S, Bhogal P, AlMatter M, Kurucz P, Grimm A, Henkes H.

Clin Neuroradiol. 2019 Jun;29(2):341-349. doi: 10.1007/s00062-018-0669-1. Epub 2018 Feb 5.


Nerve ultrasound in polyneuropathies.

Telleman JA, Grimm A, Goedee S, Visser LH, Zaidman CM.

Muscle Nerve. 2018 May;57(5):716-728. doi: 10.1002/mus.26029. Epub 2018 Jan 23.


Ultrasound and MRI of nerves for monitoring disease activity and treatment effects in chronic dysimmune neuropathies - Current concepts and future directions.

Décard BF, Pham M, Grimm A.

Clin Neurophysiol. 2018 Jan;129(1):155-167. doi: 10.1016/j.clinph.2017.10.028. Epub 2017 Nov 10. Review.


Anatomy of the sphenopalatine artery and its implications for transnasal neurosurgery.

Eordogh M, Grimm A, Gawish I, Patonay L, Reisch R, Briner HR, Baksa G.

Rhinology. 2018 Mar 1;56(1):82-88. doi: 10.4193/Rhin17.181.


A look inside the nerve - Morphology of nerve fascicles in healthy controls and patients with polyneuropathy.

Grimm A, Winter N, Rattay TW, Härtig F, Dammeier NM, Auffenberg E, Koch M, Axer H.

Clin Neurophysiol. 2017 Dec;128(12):2521-2526. doi: 10.1016/j.clinph.2017.08.022. Epub 2017 Sep 19.


Frequent genes in rare diseases: panel-based next generation sequencing to disclose causal mutations in hereditary neuropathies.

Dohrn MF, Glöckle N, Mulahasanovic L, Heller C, Mohr J, Bauer C, Riesch E, Becker A, Battke F, Hörtnagel K, Hornemann T, Suriyanarayanan S, Blankenburg M, Schulz JB, Claeys KG, Gess B, Katona I, Ferbert A, Vittore D, Grimm A, Wolking S, Schöls L, Lerche H, Korenke GC, Fischer D, Schrank B, Kotzaeridou U, Kurlemann G, Dräger B, Schirmacher A, Young P, Schlotter-Weigel B, Biskup S.

J Neurochem. 2017 Dec;143(5):507-522. doi: 10.1111/jnc.14217. Epub 2017 Nov 7.


Nerve ultrasound as follow-up tool in treated multifocal motor neuropathy.

Rattay TW, Winter N, Décard BF, Dammeier NM, Härtig F, Ceanga M, Axer H, Grimm A.

Eur J Neurol. 2017 Sep;24(9):1125-1134. doi: 10.1111/ene.13344. Epub 2017 Jul 5.


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