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Items: 1 to 50 of 92

1.

Factors Associated With 90-Day Readmission After Stroke or Transient Ischemic Attack: Linked Data From the Australian Stroke Clinical Registry.

Kilkenny MF, Dalli LL, Kim J, Sundararajan V, Andrew NE, Dewey HM, Johnston T, Alif SM, Lindley RI, Jude M, Blacker D, Gange N, Grimley R, Katzenellenbogen JM, Thrift AG, Lannin NA, Cadilhac DA; Stroke123 Investigators and AuSCR Consortium.

Stroke. 2019 Dec 11:STROKEAHA119026133. doi: 10.1161/STROKEAHA.119.026133. [Epub ahead of print]

PMID:
31822248
2.

Disparities in Antihypertensive Prescribing After Stroke: Linked Data From the Australian Stroke Clinical Registry.

Dalli LL, Kim J, Thrift AG, Andrew NE, Lannin NA, Anderson CS, Grimley R, Katzenellenbogen JM, Boyd J, Lindley RI, Pollack M, Jude M, Durairaj R, Shah D, Cadilhac DA, Kilkenny MF.

Stroke. 2019 Dec;50(12):3592-3599. doi: 10.1161/STROKEAHA.119.026823. Epub 2019 Oct 25.

PMID:
31648630
3.

Fits, faints, falls and funny turns: cost and capacity savings in Queensland from the accelerated transient attack pathway initiative (ATAP).

Blythe R, Kularatna S, White N, Graves N, Clark K, Middleton H, Grimley R.

Age Ageing. 2019 Jul 12. pii: afz086. doi: 10.1093/ageing/afz086. [Epub ahead of print]

PMID:
31297515
4.

Acute stroke patients not meeting their nutrition requirements: Investigating nutrition within the enriched environment.

Robertson ST, Grimley RS, Anstey C, Rosbergen IC.

Clin Nutr. 2019 Jun 12. pii: S0261-5614(19)30264-X. doi: 10.1016/j.clnu.2019.06.009. [Epub ahead of print]

PMID:
31235416
5.

Multicenter, Prospective, Controlled, Before-and-After, Quality Improvement Study (Stroke123) of Acute Stroke Care.

Cadilhac DA, Grimley R, Kilkenny MF, Andrew NE, Lannin NA, Hill K, Grabsch B, Levi CR, Thrift AG, Faux SG, Wakefield J, Cadigan G, Donnan GA, Middleton S, Anderson CS.

Stroke. 2019 Jun;50(6):1525-1530. doi: 10.1161/STROKEAHA.118.023075. Epub 2019 May 14.

6.

Thrombolysis Guided by Perfusion Imaging up to 9 Hours after Onset of Stroke.

Ma H, Campbell BCV, Parsons MW, Churilov L, Levi CR, Hsu C, Kleinig TJ, Wijeratne T, Curtze S, Dewey HM, Miteff F, Tsai CH, Lee JT, Phan TG, Mahant N, Sun MC, Krause M, Sturm J, Grimley R, Chen CH, Hu CJ, Wong AA, Field D, Sun Y, Barber PA, Sabet A, Jannes J, Jeng JS, Clissold B, Markus R, Lin CH, Lien LM, Bladin CF, Christensen S, Yassi N, Sharma G, Bivard A, Desmond PM, Yan B, Mitchell PJ, Thijs V, Carey L, Meretoja A, Davis SM, Donnan GA; EXTEND Investigators.

N Engl J Med. 2019 May 9;380(19):1795-1803. doi: 10.1056/NEJMoa1813046.

PMID:
31067369
7.

Assessment and selection for rehabilitation following acute stroke: a prospective cohort study in Queensland, Australia.

Grimley RS, Rosbergen IC, Gustaffson L, Horton E, Green T, Cadigan G, Cadilhac DA, Kuys S.

Clin Rehabil. 2019 Jul;33(7):1252-1263. doi: 10.1177/0269215519837585. Epub 2019 Mar 28.

PMID:
30919665
8.

Sex Differences in Care and Long-Term Mortality After Stroke: Australian Stroke Clinical Registry.

Phan HT, Gall SL, Blizzard CL, Lannin NA, Thrift AG, Anderson CS, Kim J, Grimley R, Castley HC, Hand P, Cadilhac DA.

J Womens Health (Larchmt). 2019 May;28(5):712-720. doi: 10.1089/jwh.2018.7171. Epub 2019 Mar 21.

PMID:
30900954
9.

Outcomes for Patients With In-Hospital Stroke: A Multicenter Study From the Australian Stroke Clinical Registry (AuSCR).

Cadilhac DA, Kilkenny MF, Lannin NA, Dewey HM, Levi CR, Hill K, Grabsch B, Grimley R, Blacker D, Thrift AG, Middleton S, Anderson CS, Donnan GA; Australian Stroke Clinical Registry Consortium.

J Stroke Cerebrovasc Dis. 2019 May;28(5):1302-1310. doi: 10.1016/j.jstrokecerebrovasdis.2019.01.026. Epub 2019 Feb 26.

PMID:
30824298
10.

Chest infection within 30 days of acute stroke, associated factors, survival and the benefits of stroke unit care: Analysis using linked data from the Australian Stroke Clinical Registry.

Chapman C, Cadilhac DA, Morgan P, Kilkenny MF, Grimley R, Sundararajan V, Purvis T, Johnston T, Lannin NA, Andrew NE.

Int J Stroke. 2019 Feb 21:1747493019833008. doi: 10.1177/1747493019833008. [Epub ahead of print]

PMID:
30789321
11.

Correction to: Hospital organizational context and delivery of evidence-based stroke care: a cross-sectional study.

Andrew NE, Middleton S, Grimley R, Anderson CS, Donnan GA, Lannin NA, Stroil-Salama E, Grabsch B, Kilkenny MF, Squires JE, Cadilhac DA; Stroke123 Investigators.

Implement Sci. 2019 Feb 8;14(1):13. doi: 10.1186/s13012-019-0862-x.

12.

Quality of life and age following stroke.

Kilkenny MF, Grimley R, Lannin NA.

Aging (Albany NY). 2019 Jan 28;11(3):845-846. doi: 10.18632/aging.101797. No abstract available.

13.

Hospital organizational context and delivery of evidence-based stroke care: a cross-sectional study.

Andrew NE, Middleton S, Grimley R, Anderson CS, Donnan GA, Lannin NA, Stroil-Salama E, Grabsch B, Kilkenny MF, Squires JE, Cadilhac DA; the Stroke123 Investigators.

Implement Sci. 2019 Jan 18;14(1):6. doi: 10.1186/s13012-018-0849-z. Erratum in: Implement Sci. 2019 Feb 8;14(1):13.

14.

The impact of environmental enrichment in an acute stroke unit on how and when patients undertake activities.

Rosbergen IC, Grimley RS, Hayward KS, Brauer SG.

Clin Rehabil. 2019 Apr;33(4):784-795. doi: 10.1177/0269215518820087. Epub 2018 Dec 23.

PMID:
30582368
15.

Weekend hospital discharge is associated with suboptimal care and outcomes: An observational Australian Stroke Clinical Registry study.

Kilkenny MF, Lannin NA, Levi C, Faux SG, Dewey HM, Grimley R, Hill K, Grabsch B, Kim J, Hand P, Crosby V, Gardner M, Rois-Gnecco J, Thijs V, Anderson CS, Donnan G, Middleton S, Cadilhac DA.

Int J Stroke. 2019 Jun;14(4):430-438. doi: 10.1177/1747493018806165. Epub 2018 Oct 22.

PMID:
30346259
16.

Factors influencing self-reported anxiety or depression following stroke or TIA using linked registry and hospital data.

Thayabaranathan T, Andrew NE, Kilkenny MF, Stolwyk R, Thrift AG, Grimley R, Johnston T, Sundararajan V, Lannin NA, Cadilhac DA.

Qual Life Res. 2018 Dec;27(12):3145-3155. doi: 10.1007/s11136-018-1960-y. Epub 2018 Aug 4.

PMID:
30078162
17.

Discovery of Potent, Selective, and Peripherally Restricted Pan-Trk Kinase Inhibitors for the Treatment of Pain.

Bagal SK, Andrews M, Bechle BM, Bian J, Bilsland J, Blakemore DC, Braganza JF, Bungay PJ, Corbett MS, Cronin CN, Cui JJ, Dias R, Flanagan NJ, Greasley SE, Grimley R, James K, Johnson E, Kitching L, Kraus ML, McAlpine I, Nagata A, Ninkovic S, Omoto K, Scales S, Skerratt SE, Sun J, Tran-Dubé M, Waldron GJ, Wang F, Warmus JS.

J Med Chem. 2018 Aug 9;61(15):6779-6800. doi: 10.1021/acs.jmedchem.8b00633. Epub 2018 Jul 27.

PMID:
29944371
18.

Discovery of Allosteric, Potent, Subtype Selective, and Peripherally Restricted TrkA Kinase Inhibitors.

Bagal SK, Omoto K, Blakemore DC, Bungay PJ, Bilsland JG, Clarke PJ, Corbett MS, Cronin CN, Cui JJ, Dias R, Flanagan NJ, Greasley SE, Grimley R, Johnson E, Fengas D, Kitching L, Kraus ML, McAlpine I, Nagata A, Waldron GJ, Warmus JS.

J Med Chem. 2019 Jan 10;62(1):247-265. doi: 10.1021/acs.jmedchem.8b00280. Epub 2018 May 3.

PMID:
29672039
19.

Quality of Life Is Poorer for Patients With Stroke Who Require an Interpreter: An Observational Australian Registry Study.

Kilkenny MF, Lannin NA, Anderson CS, Dewey HM, Kim J, Barclay-Moss K, Levi C, Faux S, Hill K, Grabsch B, Middleton S, Thrift AG, Grimley R, Donnan G, Cadilhac DA; AuSCR Consortium.

Stroke. 2018 Mar;49(3):761-764. doi: 10.1161/STROKEAHA.117.019771. Epub 2018 Feb 9.

PMID:
29439194
20.

Prescription of antihypertensive medication at discharge influences survival following stroke.

Andrew NE, Kim J, Thrift AG, Kilkenny MF, Lannin NA, Anderson CS, Donnan GA, Hill K, Middleton S, Levi C, Faux S, Grimley R, Gange N, Geraghty R, Ermel S, Cadilhac DA; Australian Stroke Clinical Registry Consortium.

Neurology. 2018 Feb 27;90(9):e745-e753. doi: 10.1212/WNL.0000000000005023. Epub 2018 Jan 31.

PMID:
29386279
21.
22.

Mechanistic enzymology in drug discovery: a fresh perspective.

Holdgate GA, Meek TD, Grimley RL.

Nat Rev Drug Discov. 2018 Jan;17(1):78. doi: 10.1038/nrd.2017.257. Epub 2017 Dec 15.

PMID:
29242615
23.

Mechanistic enzymology in drug discovery: a fresh perspective.

Holdgate GA, Meek TD, Grimley RL.

Nat Rev Drug Discov. 2018 Feb;17(2):115-132. doi: 10.1038/nrd.2017.219. Epub 2017 Dec 1. Review. Erratum in: Nat Rev Drug Discov. 2017 Dec 15;:.

PMID:
29192286
24.

Treatment and Outcomes of Working Aged Adults with Stroke: Results from a National Prospective Registry.

Lannin NA, Anderson CS, Kim J, Kilkenny M, Bernhardt J, Levi C, Dewey HM, Bladin C, Hand P, Castley H, Hill K, Faux S, Grimley R, Grabsch B, Middleton S, Donnan G, Cadilhac DA.

Neuroepidemiology. 2017;49(3-4):113-120. doi: 10.1159/000484141. Epub 2017 Nov 14.

PMID:
29136634
25.

Improving quality and outcomes of stroke care in hospitals: Protocol and statistical analysis plan for the Stroke123 implementation study.

Cadilhac DA, Andrew NE, Kilkenny MF, Hill K, Grabsch B, Lannin NA, Thrift AG, Anderson CS, Donnan GA, Middleton S, Grimley R.

Int J Stroke. 2018 Jan;13(1):96-106. doi: 10.1177/1747493017730741. Epub 2017 Sep 15.

PMID:
28914187
26.

Improving discharge care: the potential of a new organisational intervention to improve discharge after hospitalisation for acute stroke, a controlled before-after pilot study.

Cadilhac DA, Andrew NE, Stroil Salama E, Hill K, Middleton S, Horton E, Meade I, Kuhle S, Nelson MR, Grimley R; Australian Stroke Clinical Registry Consortium.

BMJ Open. 2017 Aug 4;7(8):e016010. doi: 10.1136/bmjopen-2017-016010.

27.

Development of a theory-informed implementation intervention to improve the triage, treatment and transfer of stroke patients in emergency departments using the Theoretical Domains Framework (TDF): the T3 Trial.

Craig LE, Taylor N, Grimley R, Cadilhac DA, McInnes E, Phillips R, Dale S, O'Connor D, Levi C, Fitzgerald M, Considine J, Grimshaw JM, Gerraty R, Cheung NW, Ward J, Middleton S.

Implement Sci. 2017 Jul 17;12(1):88. doi: 10.1186/s13012-017-0616-6.

28.

Embedding an enriched environment in an acute stroke unit increases activity in people with stroke: a controlled before-after pilot study.

Rosbergen IC, Grimley RS, Hayward KS, Walker KC, Rowley D, Campbell AM, McGufficke S, Robertson ST, Trinder J, Janssen H, Brauer SG.

Clin Rehabil. 2017 Nov;31(11):1516-1528. doi: 10.1177/0269215517705181. Epub 2017 May 1.

PMID:
28459184
29.

Risk-adjusted hospital mortality rates for stroke: evidence from the Australian Stroke Clinical Registry (AuSCR).

Cadilhac DA, Kilkenny MF, Levi CR, Lannin NA, Thrift AG, Kim J, Grabsch B, Churilov L, Dewey HM, Hill K, Faux SG, Grimley R, Castley H, Hand PJ, Wong A, Herkes GK, Gill M, Crompton D, Middleton S, Donnan GA, Anderson CS.

Med J Aust. 2017 May 1;206(8):345-350. Erratum in: Med J Aust. 2017 Aug 21;207(4):180.

PMID:
28446116
30.

Quality of Acute Care and Long-Term Quality of Life and Survival: The Australian Stroke Clinical Registry.

Cadilhac DA, Andrew NE, Lannin NA, Middleton S, Levi CR, Dewey HM, Grabsch B, Faux S, Hill K, Grimley R, Wong A, Sabet A, Butler E, Bladin CF, Bates TR, Groot P, Castley H, Donnan GA, Anderson CS; Australian Stroke Clinical Registry Consortium.

Stroke. 2017 Apr;48(4):1026-1032. doi: 10.1161/STROKEAHA.116.015714. Epub 2017 Mar 3.

PMID:
28258253
31.

Testing a systematic approach to identify and prioritise barriers to successful implementation of a complex healthcare intervention.

Craig LE, Churilov L, Olenko L, Cadilhac DA, Grimley R, Dale S, Martinez-Garduno C, McInnes E, Considine J, Grimshaw JM, Middleton S.

BMC Med Res Methodol. 2017 Feb 7;17(1):24. doi: 10.1186/s12874-017-0298-4.

32.

The effect of an enriched environment on activity levels in people with stroke in an acute stroke unit: protocol for a before-after pilot study.

Rosbergen IC, Grimley RS, Hayward KS, Walker KC, Rowley D, Campbell AM, McGufficke S, Robertson ST, Trinder J, Janssen H, Brauer SG.

Pilot Feasibility Stud. 2016 Aug 2;2:36. eCollection 2016.

34.

Better outcomes for hospitalized patients with TIA when in stroke units: An observational study.

Phan TG, Srikanth V, Cadilhac DA, Grimley R, Donnan GA, Anderson CS.

Neurology. 2016 Oct 18;87(16):1745-1746. No abstract available.

PMID:
27754911
35.

Better outcomes for hospitalized patients with TIA when in stroke units: An observational study.

Cadilhac DA, Kim J, Lannin NA, Levi CR, Dewey HM, Hill K, Faux S, Andrew NE, Kilkenny MF, Grimley R, Thrift AG, Grabsch B, Middleton S, Anderson CS, Donnan GA; Australian Stroke Clinical Registry Consortium.

Neurology. 2016 May 31;86(22):2042-8. doi: 10.1212/WNL.0000000000002715. Epub 2016 May 4.

36.

Design and development of histone deacetylase (HDAC) chemical probes for cell-based profiling.

Albrow VE, Grimley RL, Clulow J, Rose CR, Sun J, Warmus JS, Tate EW, Jones LH, Storer RI.

Mol Biosyst. 2016 May 24;12(6):1781-9. doi: 10.1039/c6mb00109b.

PMID:
27021930
37.

Triage, treatment, and transfer: evidence-based clinical practice recommendations and models of nursing care for the first 72 hours of admission to hospital for acute stroke.

Middleton S, Grimley R, Alexandrov AW.

Stroke. 2015 Feb;46(2):e18-25. doi: 10.1161/STROKEAHA.114.006139. Epub 2015 Jan 6. Review. No abstract available. Erratum in: Stroke. 2015 May;46(5):e129.

PMID:
25563641
38.

(R)-PFI-2 is a potent and selective inhibitor of SETD7 methyltransferase activity in cells.

Barsyte-Lovejoy D, Li F, Oudhoff MJ, Tatlock JH, Dong A, Zeng H, Wu H, Freeman SA, Schapira M, Senisterra GA, Kuznetsova E, Marcellus R, Allali-Hassani A, Kennedy S, Lambert JP, Couzens AL, Aman A, Gingras AC, Al-Awar R, Fish PV, Gerstenberger BS, Roberts L, Benn CL, Grimley RL, Braam MJ, Rossi FM, Sudol M, Brown PJ, Bunnage ME, Owen DR, Zaph C, Vedadi M, Arrowsmith CH.

Proc Natl Acad Sci U S A. 2014 Sep 2;111(35):12853-8. doi: 10.1073/pnas.1407358111. Epub 2014 Aug 18.

39.

STroke imAging pRevention and treatment (START): A longitudinal stroke cohort study: Clinical trials protocol.

Carey LM, Crewther S, Salvado O, Lindén T, Connelly A, Wilson W, Howells DW, Churilov L, Ma H, Tse T, Rose S, Palmer S, Bougeat P, Campbell BC, Christensen S, Macaulay SL, Favaloro J, O' Collins V, McBride S, Bates S, Cowley E, Dewey H, Wijeratne T, Gerraty R, Phan TG, Yan B, Parsons MW, Bladin C, Barber PA, Read S, Wong A, Lee A, Kleinig T, Hankey GJ, Blacker D, Markus R, Leyden J, Krause M, Grimley R, Mahant N, Jannes J, Sturm J, Davis SM, Donnan GA; START Research Team.

Int J Stroke. 2015 Jun;10(4):636-44. doi: 10.1111/ijs.12190. Epub 2013 Nov 10.

PMID:
24206623
40.

Discovery of novel irreversible inhibitors of interleukin (IL)-2-inducible tyrosine kinase (Itk) by targeting cysteine 442 in the ATP pocket.

Harling JD, Deakin AM, Campos S, Grimley R, Chaudry L, Nye C, Polyakova O, Bessant CM, Barton N, Somers D, Barrett J, Graves RH, Hanns L, Kerr WJ, Solari R.

J Biol Chem. 2013 Sep 27;288(39):28195-206. doi: 10.1074/jbc.M113.474114. Epub 2013 Aug 9.

41.

Identification of novel interacting partners of Sirtuin6.

Polyakova O, Borman S, Grimley R, Vamathevan J, Hayes B, Solari R.

PLoS One. 2012;7(12):e51555. doi: 10.1371/journal.pone.0051555. Epub 2012 Dec 11.

42.

Over expression of wild type or a catalytically dead mutant of Sirtuin 6 does not influence NFκB responses.

Grimley R, Polyakova O, Vamathevan J, McKenary J, Hayes B, Patel C, Smith J, Bridges A, Fosberry A, Bhardwaja A, Mouzon B, Chung CW, Barrett N, Richmond N, Modha S, Solari R.

PLoS One. 2012;7(7):e39847. doi: 10.1371/journal.pone.0039847. Epub 2012 Jul 6. Erratum in: PLoS One. 2012;7(9). doi:10.1371/annotation/9c1a5765-6471-401f-bc74-a916c8ead46f.

43.

A case of bilateral lower cranial nerve palsies after base of skull trauma with complex management issues: case report and review of the literature.

Lehn AC, Lettieri J, Grimley R.

Neurologist. 2012 May;18(3):152-4. doi: 10.1097/NRL.0b013e318247bb6f. Review.

PMID:
22549358
44.

Dual pathology of corticobasal degeneration and Parkinson's disease in a patient with clinical features of progressive supranuclear palsy.

Mooney T, Tampiyappa A, Robertson T, Grimley R, Burke C, Ng K, Patrikios P.

Neurol India. 2011 Nov-Dec;59(6):887-90. doi: 10.4103/0028-3886.91371.

PMID:
22234205
45.

A multicentre, randomized, double-blinded, placebo-controlled Phase III study to investigate EXtending the time for Thrombolysis in Emergency Neurological Deficits (EXTEND).

Ma H, Parsons MW, Christensen S, Campbell BC, Churilov L, Connelly A, Yan B, Bladin C, Phan T, Barber AP, Read S, Hankey GJ, Markus R, Wijeratne T, Grimley R, Mahant N, Kleinig T, Sturm J, Lee A, Blacker D, Gerraty R, Krause M, Desmond PM, McBride SJ, Carey L, Howells DW, Hsu CY, Davis SM, Donnan GA; EXTEND investigators.

Int J Stroke. 2012 Jan;7(1):74-80. doi: 10.1111/j.1747-4949.2011.00730.x.

PMID:
22188854
46.

Discovery and characterization of small molecule inhibitors of the BET family bromodomains.

Chung CW, Coste H, White JH, Mirguet O, Wilde J, Gosmini RL, Delves C, Magny SM, Woodward R, Hughes SA, Boursier EV, Flynn H, Bouillot AM, Bamborough P, Brusq JM, Gellibert FJ, Jones EJ, Riou AM, Homes P, Martin SL, Uings IJ, Toum J, Clement CA, Boullay AB, Grimley RL, Blandel FM, Prinjha RK, Lee K, Kirilovsky J, Nicodeme E.

J Med Chem. 2011 Jun 9;54(11):3827-38. doi: 10.1021/jm200108t. Epub 2011 May 13.

PMID:
21568322
47.

National survey of management of transient ischaemic attack in Australia: take immediate action.

Price CJ, Blacker DJ, Grimley RS, Dewey HM, Gerraty RP, Koblar SA, Denisenko SM, Storey CE, Bladin CF, Hill KM.

Med J Aust. 2009 Jul 6;191(1):17-20.

PMID:
19580530
48.

Immunomodulatory activity of a methionine aminopeptidase-2 inhibitor on B cell differentiation.

Priest RC, Spaull J, Buckton J, Grimley RL, Sims M, Binks M, Malhotra R.

Clin Exp Immunol. 2009 Mar;155(3):514-22. doi: 10.1111/j.1365-2249.2008.03843.x. Epub 2008 Dec 3.

49.

Abdominal aortic aneurysm surgery in a district general hospital: a 15-years experience.

Qureshi NA, Rehman A, Slater N, Moss E, Shiralkar S, Patel RT, Grimley RP, Jayatunga AP.

Ann Vasc Surg. 2007 Nov;21(6):749-53. Epub 2007 May 18.

PMID:
17512166
50.

Bridging the gap between in silico and cell-based analysis of the nuclear factor-kappaB signaling pathway by in vitro studies of IKK2.

Ihekwaba AE, Wilkinson SJ, Waithe D, Broomhead DS, Li P, Grimley RL, Benson N.

FEBS J. 2007 Apr;274(7):1678-90. Epub 2007 Feb 20.

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