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Items: 50

1.

In vitro and in vivo pharmacokinetic characterization of mavacamten, a first-in-class small molecule allosteric modulator of beta cardiac myosin.

Grillo MP, Erve JCL, Dick R, Driscoll JP, Haste N, Markova S, Brun P, Carlson TJ, Evanchik M.

Xenobiotica. 2018 Oct 1:1-16. doi: 10.1080/00498254.2018.1495856. [Epub ahead of print]

PMID:
30044681
2.

Self-reported HIV-positive status but subsequent HIV-negative test result using rapid diagnostic testing algorithms among seven sub-Saharan African military populations.

Harbertson J, Hale BR, Tran BR, Thomas AG, Grillo MP, Jacobs MB, McAnany J, Shaffer RA.

PLoS One. 2017 Jul 7;12(7):e0180796. doi: 10.1371/journal.pone.0180796. eCollection 2017.

3.

Voluntary Medical Male Circumcision among Rwanda Defense Force Members.

Grillo MP, Djibo DA, Macera CA, Murego C, Zimulinda E, Sebagabo M, Gatsinzi V.

Curr HIV Res. 2017;15(2):109-115. doi: 10.2174/1570162X15666170517095733.

PMID:
28521718
4.

Global HIV Prevention, Testing, and Counseling in Military Populations.

Grillo MP, Sloan M, Wankie C, Woodland K, Reader E, Porter B, Shaffer R, Macera CA, Bulterys M.

Curr HIV Res. 2017;15(2):95-101. doi: 10.2174/1570162X15666170516170412. Review.

PMID:
28521713
5.

Prevention Interventions for People Living with HIV in Military Settings.

Grillo MP, Sloan M, Wankie C, Woodland K, Reader E, Porter B, Macera CA, Shaffer RA.

Curr HIV Res. 2017;15(2):90-94. doi: 10.2174/1570162X15666170516165331. Review.

PMID:
28176645
6.

Evaluation of PIMATM CD4 System for Decentralization of Immunological Monitoring of HIV-Infected Patients in Senegal.

Faye B, Mbow M, Cheikh Seck M, Mbengue B, Wade D, Camara M, Cissé C, Diouf SG, Ndao B, Djibo A, Sylla Niang MD, Ndiaye T, Grillo MP, Dièye A.

PLoS One. 2016 May 11;11(5):e0154000. doi: 10.1371/journal.pone.0154000. eCollection 2016.

7.

Sexually transmitted infections and sexual behaviour of deploying shipboard US military personnel: a cross-sectional analysis.

Harbertson J, Scott PT, Moore J, Wolf M, Morris J, Thrasher S, D'Onofrio M, Grillo MP, Jacobs MB, Tran BR, Tian J, Ito SI, McAnany J, Michael N, Hale BR.

Sex Transm Infect. 2015 Dec;91(8):581-8. doi: 10.1136/sextrans-2015-052163.

8.

The impact of an educational film on promoting knowledge and attitudes toward HIV in soldiers of the Serbian Armed Forces.

Jadranin Ž, Dedić G, Vaughan F, Grillo MP, Šuljagić V.

Vojnosanit Pregl. 2015 Jul;72(7):569-75.

PMID:
26364448
9.

Detecting reactive drug metabolites for reducing the potential for drug toxicity.

Grillo MP.

Expert Opin Drug Metab Toxicol. 2015;11(8):1281-302. doi: 10.1517/17425255.2015.1048222. Epub 2015 May 25. Review.

PMID:
26005795
10.

Military HIV policy assessment in sub-Saharan Africa.

Thomas AG, Grillo MP, Djibo DA, Hale B, Shaffer RA.

Mil Med. 2014 Jul;179(7):773-7. doi: 10.7205/MILMED-D-13-00495.

PMID:
25003863
11.

Structure-assisted discovery of the first non-retinoid ligands for Retinol-Binding Protein 4.

Wang Y, Connors R, Fan P, Wang X, Wang Z, Liu J, Kayser F, Medina JC, Johnstone S, Xu H, Thibault S, Walker N, Conn M, Zhang Y, Liu Q, Grillo MP, Motani A, Coward P, Wang Z.

Bioorg Med Chem Lett. 2014 Jul 1;24(13):2885-91. doi: 10.1016/j.bmcl.2014.04.089. Epub 2014 May 2.

PMID:
24835984
12.

HIV infection and risk factors among the armed forces personnel stationed in Kinshasa, Democratic Republic of Congo.

Rimoin AW, Hoff NA, Djoko CF, Kisalu NK, Kashamuka M, Tamoufe U, LeBreton M, Kayembe PK, Muyembe JJ, Kitchen CR, Saylors K, Fair J, Doshi R, Papworth E, Mpoudi-Ngole E, Grillo MP, Tshala F, Peeters M, Wolfe ND.

Int J STD AIDS. 2015 Mar;26(3):187-95. doi: 10.1177/0956462414533672. Epub 2014 May 14.

PMID:
24828556
13.

Discovery and optimization of 5-(2-((1-(phenylsulfonyl)-1,2,3,4-tetrahydroquinolin-7-yl)oxy)pyridin-4-yl)-1,2,4-oxadiazoles as novel gpr119 agonists.

Wang Y, Yu M, Zhu J, Zhang JK, Kayser F, Medina JC, Siegler K, Conn M, Shan B, Grillo MP, Liu JJ, Coward P.

Bioorg Med Chem Lett. 2014 Feb 15;24(4):1133-7. doi: 10.1016/j.bmcl.2013.12.127. Epub 2014 Jan 8.

PMID:
24440299
14.

Discovery and optimization of N-(3-(1,3-dioxo-2,3-dihydro-1H-pyrrolo[3,4-c]pyridin-4-yloxy)phenyl)benzenesulfonamides as novel GPR119 agonists.

Yu M, Ken Zhang J, Wang Y, Zhu J, Kayser F, Medina JC, Siegler K, Conn M, Shan B, Grillo MP, Coward P, Jim Liu J.

Bioorg Med Chem Lett. 2014 Jan 1;24(1):156-60. doi: 10.1016/j.bmcl.2013.11.053. Epub 2013 Dec 1.

PMID:
24332491
15.

Metabolism-guided discovery of a potent and orally bioavailable urea-based calcimimetic for the treatment of secondary hyperparathyroidism.

Wehn PM, Harrington PE, Carlson TJ, Davis J, Deprez P, Fotsch CH, Grillo MP, Lu JY, Morony S, Pattabiraman K, Poon SF, Reagan JD, St Jean DJ Jr, Temal T, Wang M, Yang Y, Henley C 3rd, Lively SE.

Bioorg Med Chem Lett. 2013 Dec 15;23(24):6625-8. doi: 10.1016/j.bmcl.2013.10.050. Epub 2013 Oct 31.

PMID:
24215889
16.

Discovery and optimization of arylsulfonyl 3-(pyridin-2-yloxy)anilines as novel GPR119 agonists.

Zhang JK, Li AR, Yu M, Wang Y, Zhu J, Kayser F, Medina JC, Siegler K, Conn M, Shan B, Grillo MP, Eksterowicz J, Coward P, Liu JJ.

Bioorg Med Chem Lett. 2013 Jun 15;23(12):3609-13. doi: 10.1016/j.bmcl.2013.04.014. Epub 2013 Apr 15.

PMID:
23648181
17.

Interaction of γ-glutamyltranspeptidase with ibuprofen-S-acyl-glutathione in vitro and in vivo in human.

Grillo MP, Lohr MT, Khera S.

Drug Metab Dispos. 2013 Jan;41(1):111-21. doi: 10.1124/dmd.112.048645. Epub 2012 Oct 10.

PMID:
23052971
18.

Metabolic activation of mefenamic acid leading to mefenamyl-S-acyl-glutathione adduct formation in vitro and in vivo in rat.

Grillo MP, Tadano Lohr M, Wait JC.

Drug Metab Dispos. 2012 Aug;40(8):1515-26. doi: 10.1124/dmd.112.046102. Epub 2012 May 10.

PMID:
22577085
19.

Effect of culture time on the basal expression levels of drug transporters in sandwich-cultured primary rat hepatocytes.

Tchaparian EH, Houghton JS, Uyeda C, Grillo MP, Jin L.

Drug Metab Dispos. 2011 Dec;39(12):2387-94. doi: 10.1124/dmd.111.039545. Epub 2011 Aug 24.

20.

Constituents in kava extracts potentially involved in hepatotoxicity: a review.

Olsen LR, Grillo MP, Skonberg C.

Chem Res Toxicol. 2011 Jul 18;24(7):992-1002. doi: 10.1021/tx100412m. Epub 2011 May 3. Review.

PMID:
21506562
22.

HIV type 1 pol gene diversity and genotypic antiretroviral drug resistance mutations in Malabo, Equatorial Guinea.

Djoko CF, Wolfe ND, Vidal N, Tamoufe U, Montavon C, LeBreton M, Pike BL, Fair J, Mbacham WF, Benito A, Rimoin AW, Saylors K, Mpoudi-Ngole E, Grillo MP, Peeters M.

AIDS Res Hum Retroviruses. 2010 Sep;26(9):1027-31. doi: 10.1089/aid.2010.0046.

23.

Stereoselective flunoxaprofen-S-acyl-glutathione thioester formation mediated by acyl-CoA formation in rat hepatocytes.

Grillo MP, Wait JC, Tadano Lohr M, Khera S, Benet LZ.

Drug Metab Dispos. 2010 Jan;38(1):133-42. doi: 10.1124/dmd.109.029371.

24.

Covalent binding of phenylacetic acid to protein in incubations with freshly isolated rat hepatocytes.

Grillo MP, Lohr MT.

Drug Metab Dispos. 2009 May;37(5):1073-82. doi: 10.1124/dmd.108.026153. Epub 2009 Feb 5.

PMID:
19196839
25.

Gamma-glutamyltranspeptidase-mediated degradation of diclofenac-S-acyl-glutathione in vitro and in vivo in rat.

Grillo MP, Hua F, March KL, Benet LZ, Knutson CG, Ware JA.

Chem Res Toxicol. 2008 Oct;21(10):1933-8. doi: 10.1021/tx800073p. Epub 2008 Aug 12.

PMID:
18693772
26.

Enantioselective formation of ibuprofen-S-acyl-glutathione in vitro in incubations of ibuprofen with rat hepatocytes.

Grillo MP, Hua F.

Chem Res Toxicol. 2008 Sep;21(9):1749-59. doi: 10.1021/tx800098h. Epub 2008 Aug 5.

PMID:
18680316
27.

A novel bioactivation pathway for 2-[2-(2,6-dichlorophenyl)aminophenyl]ethanoic acid (diclofenac) initiated by cytochrome P450-mediated oxidative decarboxylation.

Grillo MP, Ma J, Teffera Y, Waldon DJ.

Drug Metab Dispos. 2008 Sep;36(9):1740-4. doi: 10.1124/dmd.108.021287. Epub 2008 Jun 9.

PMID:
18541695
28.

Metabolic activation of carboxylic acids.

Skonberg C, Olsen J, Madsen KG, Hansen SH, Grillo MP.

Expert Opin Drug Metab Toxicol. 2008 Apr;4(4):425-38. doi: 10.1517/17425255.4.4.425 . Review.

PMID:
18433345
29.

Differential effects of fibrates on the metabolic activation of 2-phenylpropionic acid in rats.

Li C, Grillo MP, Badagnani I, Fife KL, Benet LZ.

Drug Metab Dispos. 2008 Apr;36(4):682-7. doi: 10.1124/dmd.107.017764. Epub 2008 Jan 10.

PMID:
18187563
30.

Development of a psychological treatment service for pruritic skin conditions.

Long D, Long RA, Grillo MP, Marshman G.

Australas J Dermatol. 2006 Nov;47(4):237-41.

PMID:
17034464
31.
32.
33.

Studies on the chemical reactivity of diclofenac acyl glucuronide with glutathione: identification of diclofenac-S-acyl-glutathione in rat bile.

Grillo MP, Knutson CG, Sanders PE, Waldon DJ, Hua F, Ware JA.

Drug Metab Dispos. 2003 Nov;31(11):1327-36.

PMID:
14570764
34.

Exploration of in vitro pro-drug activation and futile cycling by glutathione S-transferases: thiol ester hydrolysis and inhibitor maturation.

Ibarra C, Grillo MP, Lo Bello M, Nucettelli M, Bammler TK, Atkins WM.

Arch Biochem Biophys. 2003 Jun 15;414(2):303-11.

PMID:
12781783
35.

Covalent binding of 2-phenylpropionyl-S-acyl-CoA thioester to tissue proteins in vitro.

Li C, Olurinde MO, Hodges LM, Grillo MP, Benet LZ.

Drug Metab Dispos. 2003 Jun;31(6):727-30.

PMID:
12756204
36.

In vivo mechanistic studies on the metabolic activation of 2-phenylpropionic acid in rat.

Li C, Grillo MP, Benet LZ.

J Pharmacol Exp Ther. 2003 Apr;305(1):250-6.

PMID:
12649376
37.

In vitro studies on the chemical reactivity of 2,4-dichlorophenoxyacetyl-S-acyl-CoA thioester.

Li C, Grillo MP, Benet LZ.

Toxicol Appl Pharmacol. 2003 Mar 1;187(2):101-9.

PMID:
12649042
38.

Enantioselective covalent binding of 2-phenylpropionic Acid to protein in vitro in rat hepatocytes.

Li C, Benet LZ, Grillo MP.

Chem Res Toxicol. 2002 Nov;15(11):1480-7.

PMID:
12437340
39.
40.

Studies on the reactivity of clofibryl-S-acyl-CoA thioester with glutathione in vitro.

Grillo MP, Benet LZ.

Drug Metab Dispos. 2002 Jan;30(1):55-62.

PMID:
11744612
41.
42.

Effect of alpha-fluorination of valproic acid on valproyl-S-acyl-CoA formation in vivo in rats.

Grillo MP, Chiellini G, Tonelli M, Benet LZ.

Drug Metab Dispos. 2001 Sep;29(9):1210-5.

PMID:
11502730
43.

Thiol ester hydrolysis catalyzed by glutathione S-transferase A1-1.

Dietze EC, Grillo MP, Kalhorn T, Nieslanik BS, Jochheim CM, Atkins WM.

Biochemistry. 1998 Oct 20;37(42):14948-57.

PMID:
9778372
45.

Developmentally regulated expression of the CYP4A genes in the spontaneously hypertensive rat kidney.

Kroetz DL, Huse LM, Thuresson A, Grillo MP.

Mol Pharmacol. 1997 Sep;52(3):362-72.

PMID:
9281597
46.

Lack of utility of routine chest radiographs in HIV-infected patients.

Olson PE, Wallace MR, Grillo MP, Rossetti RJ, Miller LK.

AIDS. 1996 Apr;10(4):446-7. No abstract available.

PMID:
8728054
47.
48.

Metabolic chiral inversion of flurbiprofen-CoA in vitro.

Porubek DJ, Sanins SM, Stephens JR, Grillo MP, Kaiser DG, Halstead GW, Adams WJ, Baillie TA.

Biochem Pharmacol. 1991 Jun 21;42(1):R1-4. No abstract available.

PMID:
2069582
49.

S-(N-methylcarbamoyl)glutathione: a reactive S-linked metabolite of methyl isocyanate.

Pearson PG, Slatter JG, Rashed MS, Han DH, Grillo MP, Baillie TA.

Biochem Biophys Res Commun. 1990 Jan 15;166(1):245-50.

PMID:
2302207
50.

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