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Items: 1 to 50 of 206

1.

Detection of early breast cancer beyond mammographic screening: a promising biomarker panel.

Hamann M, Grill S, Struck J, Bergmann A, Hartmann O, Pölcher M, Kiechle M.

Biomark Med. 2019 Sep;13(13):1107-1117. doi: 10.2217/bmm-2019-0085. Epub 2019 Aug 30.

PMID:
31468986
2.

Guiding self-organized pattern formation in cell polarity establishment.

Gross P, Kumar KV, Goehring NW, Bois JS, Hoege C, Jülicher F, Grill SW.

Nat Phys. 2019 Jul 2;15(3):293-300. doi: 10.1038/s41567-018-0358-7. Epub 2018 Dec 3.

3.

Two Separation-of-Function Isoforms of Human TPP1 Dictate Telomerase Regulation in Somatic and Germ Cells.

Grill S, Bisht K, Tesmer VM, Shami AN, Hammoud SS, Nandakumar J.

Cell Rep. 2019 Jun 18;27(12):3511-3521.e7. doi: 10.1016/j.celrep.2019.05.073.

4.

Short-Term Prediction of Adverse Outcomes Using the sFlt-1 (Soluble fms-Like Tyrosine Kinase 1)/PlGF (Placental Growth Factor) Ratio in Asian Women With Suspected Preeclampsia.

Bian X, Biswas A, Huang X, Lee KJ, Li TK, Masuyama H, Ohkuchi A, Park JS, Saito S, Tan KH, Yamamoto T, Dietl A, Grill S, Verhagen-Kamerbeek WDJ, Shim JY, Hund M.

Hypertension. 2019 Jul;74(1):164-172. doi: 10.1161/HYPERTENSIONAHA.119.12760. Epub 2019 Jun 12.

5.

Large scale multifactorial likelihood quantitative analysis of BRCA1 and BRCA2 variants: An ENIGMA resource to support clinical variant classification.

Parsons MT, Tudini E, Li H, Hahnen E, Wappenschmidt B, Feliubadaló L, Aalfs CM, Agata S, Aittomäki K, Alducci E, Alonso-Cerezo MC, Arnold N, Auber B, Austin R, Azzollini J, Balmaña J, Barbieri E, Bartram CR, Blanco A, Blümcke B, Bonache S, Bonanni B, Borg Å, Bortesi B, Brunet J, Bruzzone C, Bucksch K, Cagnoli G, Caldés T, Caliebe A, Caligo MA, Calvello M, Capone GL, Caputo SM, Carnevali I, Carrasco E, Caux-Moncoutier V, Cavalli P, Cini G, Clarke EM, Concolino P, Cops EJ, Cortesi L, Couch FJ, Darder E, de la Hoya M, Dean M, Debatin I, Del Valle J, Delnatte C, Derive N, Diez O, Ditsch N, Domchek SM, Dutrannoy V, Eccles DM, Ehrencrona H, Enders U, Evans DG, Farra C, Faust U, Felbor U, Feroce I, Fine M, Foulkes WD, Galvao HCR, Gambino G, Gehrig A, Gensini F, Gerdes AM, Germani A, Giesecke J, Gismondi V, Gómez C, Gómez Garcia EB, González S, Grau E, Grill S, Gross E, Guerrieri-Gonzaga A, Guillaud-Bataille M, Gutiérrez-Enríquez S, Haaf T, Hackmann K, Hansen TVO, Harris M, Hauke J, Heinrich T, Hellebrand H, Herold KN, Honisch E, Horvath J, Houdayer C, Hübbel V, Iglesias S, Izquierdo A, James PA, Janssen LAM, Jeschke U, Kaulfuß S, Keupp K, Kiechle M, Kölbl A, Krieger S, Kruse TA, Kvist A, Lalloo F, Larsen M, Lattimore VL, Lautrup C, Ledig S, Leinert E, Lewis AL, Lim J, Loeffler M, López-Fernández A, Lucci-Cordisco E, Maass N, Manoukian S, Marabelli M, Matricardi L, Meindl A, Michelli RD, Moghadasi S, Moles-Fernández A, Montagna M, Montalban G, Monteiro AN, Montes E, Mori L, Moserle L, Müller CR, Mundhenke C, Naldi N, Nathanson KL, Navarro M, Nevanlinna H, Nichols CB, Niederacher D, Nielsen HR, Ong KR, Pachter N, Palmero EI, Papi L, Pedersen IS, Peissel B, Perez-Segura P, Pfeifer K, Pineda M, Pohl-Rescigno E, Poplawski NK, Porfirio B, Quante AS, Ramser J, Reis RM, Revillion F, Rhiem K, Riboli B, Ritter J, Rivera D, Rofes P, Rump A, Salinas M, Sánchez de Abajo AM, Schmidt G, Schoenwiese U, Seggewiß J, Solanes A, Steinemann D, Stiller M, Stoppa-Lyonnet D, Sullivan KJ, Susman R, Sutter C, Tavtigian SV, Teo SH, Teulé A, Thomassen M, Tibiletti MG, Tischkowitz M, Tognazzo S, Toland AE, Tornero E, Törngren T, Torres-Esquius S, Toss A, Trainer AH, Tucker KM, van Asperen CJ, van Mackelenbergh MT, Varesco L, Vargas-Parra G, Varon R, Vega A, Velasco Á, Vesper AS, Viel A, Vreeswijk MPG, Wagner SA, Waha A, Walker LC, Walters RJ, Wang-Gohrke S, Weber BHF, Weichert W, Wieland K, Wiesmüller L, Witzel I, Wöckel A, Woodward ER, Zachariae S, Zampiga V, Zeder-Göß C, Investigators K, Lázaro C, De Nicolo A, Radice P, Engel C, Schmutzler RK, Goldgar DE, Spurdle AB.

Hum Mutat. 2019 Sep;40(9):1557-1578. doi: 10.1002/humu.23818.

6.

Publisher Correction: Attachment of the blastoderm to the vitelline envelope affects gastrulation of insects.

Münster S, Jain A, Mietke A, Pavlopoulos A, Grill SW, Tomancak P.

Nature. 2019 Apr;568(7753):E14. doi: 10.1038/s41586-019-1143-1.

PMID:
30971828
7.

Attachment of the blastoderm to the vitelline envelope affects gastrulation of insects.

Münster S, Jain A, Mietke A, Pavlopoulos A, Grill SW, Tomancak P.

Nature. 2019 Apr;568(7752):395-399. doi: 10.1038/s41586-019-1044-3. Epub 2019 Mar 27. Erratum in: Nature. 2019 Apr 10;:.

PMID:
30918398
8.

Aurora A depletion reveals centrosome-independent polarization mechanism in Caenorhabditis elegans.

Klinkert K, Levernier N, Gross P, Gentili C, von Tobel L, Pierron M, Busso C, Herrman S, Grill SW, Kruse K, Gönczy P.

Elife. 2019 Feb 26;8. pii: e44552. doi: 10.7554/eLife.44552.

9.

Cadazolid for the treatment of Clostridium difficile infection: results of two double-blind, placebo-controlled, non-inferiority, randomised phase 3 trials.

Gerding DN, Cornely OA, Grill S, Kracker H, Marrast AC, Nord CE, Talbot GH, Buitrago M, Gheorghe Diaconescu I, Murta de Oliveira C, Preotescu L, Pullman J, Louie TJ, Wilcox MH.

Lancet Infect Dis. 2019 Mar;19(3):265-274. doi: 10.1016/S1473-3099(18)30614-5. Epub 2019 Jan 29.

10.

Morphogenetic degeneracies in the actomyosin cortex.

Naganathan SR, Fürthauer S, Rodriguez J, Fievet BT, Jülicher F, Ahringer J, Cannistraci CV, Grill SW.

Elife. 2018 Oct 22;7. pii: e37677. doi: 10.7554/eLife.37677.

11.

Soluble fms-like tyrosine kinase-1 to placental growth factor ratio: ruling out pre-eclampsia for up to 4 weeks and value of retesting.

Zeisler H, Llurba E, Chantraine FJ, Vatish M, Staff AC, Sennström M, Olovsson M, Brennecke SP, Stepan H, Allegranza D, Schoedl M, Grill S, Hund M, Verlohren S.

Ultrasound Obstet Gynecol. 2019 Mar;53(3):367-375. doi: 10.1002/uog.19178. Epub 2019 Feb 4.

12.

Modifiable Lifestyle Factors: Opportunities for (Hereditary) Breast Cancer Prevention - a Narrative Review.

Lammert J, Grill S, Kiechle M.

Breast Care (Basel). 2018 Apr;13(2):109-114. doi: 10.1159/000488995. Epub 2018 Apr 20. Review.

13.

Protein Dynamics in Complex DNA Lesions.

Aleksandrov R, Dotchev A, Poser I, Krastev D, Georgiev G, Panova G, Babukov Y, Danovski G, Dyankova T, Hubatsch L, Ivanova A, Atemin A, Nedelcheva-Veleva MN, Hasse S, Sarov M, Buchholz F, Hyman AA, Grill SW, Stoynov SS.

Mol Cell. 2018 Mar 15;69(6):1046-1061.e5. doi: 10.1016/j.molcel.2018.02.016.

14.

Hydrodynamic theory of active matter.

Jülicher F, Grill SW, Salbreux G.

Rep Prog Phys. 2018 Jul;81(7):076601. doi: 10.1088/1361-6633/aab6bb. Epub 2018 Mar 15.

PMID:
29542442
15.

Gene panel testing of 5589 BRCA1/2-negative index patients with breast cancer in a routine diagnostic setting: results of the German Consortium for Hereditary Breast and Ovarian Cancer.

Hauke J, Horvath J, Groß E, Gehrig A, Honisch E, Hackmann K, Schmidt G, Arnold N, Faust U, Sutter C, Hentschel J, Wang-Gohrke S, Smogavec M, Weber BHF, Weber-Lassalle N, Weber-Lassalle K, Borde J, Ernst C, Altmüller J, Volk AE, Thiele H, Hübbel V, Nürnberg P, Keupp K, Versmold B, Pohl E, Kubisch C, Grill S, Paul V, Herold N, Lichey N, Rhiem K, Ditsch N, Ruckert C, Wappenschmidt B, Auber B, Rump A, Niederacher D, Haaf T, Ramser J, Dworniczak B, Engel C, Meindl A, Schmutzler RK, Hahnen E.

Cancer Med. 2018 Apr;7(4):1349-1358. doi: 10.1002/cam4.1376. Epub 2018 Mar 9.

16.

Non-invasive perturbations of intracellular flow reveal physical principles of cell organization.

Mittasch M, Gross P, Nestler M, Fritsch AW, Iserman C, Kar M, Munder M, Voigt A, Alberti S, Grill SW, Kreysing M.

Nat Cell Biol. 2018 Mar;20(3):344-351. doi: 10.1038/s41556-017-0032-9. Epub 2018 Feb 5.

PMID:
29403036
17.

The N Terminus of the OB Domain of Telomere Protein TPP1 Is Critical for Telomerase Action.

Grill S, Tesmer VM, Nandakumar J.

Cell Rep. 2018 Jan 30;22(5):1132-1140. doi: 10.1016/j.celrep.2018.01.012.

18.

Impaired DNA damage response signaling by FUS-NLS mutations leads to neurodegeneration and FUS aggregate formation.

Naumann M, Pal A, Goswami A, Lojewski X, Japtok J, Vehlow A, Naujock M, Günther R, Jin M, Stanslowsky N, Reinhardt P, Sterneckert J, Frickenhaus M, Pan-Montojo F, Storkebaum E, Poser I, Freischmidt A, Weishaupt JH, Holzmann K, Troost D, Ludolph AC, Boeckers TM, Liebau S, Petri S, Cordes N, Hyman AA, Wegner F, Grill SW, Weis J, Storch A, Hermann A.

Nat Commun. 2018 Jan 23;9(1):335. doi: 10.1038/s41467-017-02299-1.

19.

Phase separation of a yeast prion protein promotes cellular fitness.

Franzmann TM, Jahnel M, Pozniakovsky A, Mahamid J, Holehouse AS, Nüske E, Richter D, Baumeister W, Grill SW, Pappu RV, Hyman AA, Alberti S.

Science. 2018 Jan 5;359(6371). pii: eaao5654. doi: 10.1126/science.aao5654.

PMID:
29301985
20.

Risk factors for tooth loss in middle and older age after up to 10 years: An observational cohort study.

Hassel AJ, Safaltin V, Grill S, Schröder J, Wahl HW, Klotz AL, Habibi E, Rammelsberg P, Zenthöfer A.

Arch Oral Biol. 2018 Feb;86:7-12. doi: 10.1016/j.archoralbio.2017.11.001. Epub 2017 Nov 6.

PMID:
29132069
21.

Feasibility of structured endurance training and Mediterranean diet in BRCA1 and BRCA2 mutation carriers - an interventional randomized controlled multicenter trial (LIBRE-1).

Kiechle M, Dukatz R, Yahiaoui-Doktor M, Berling A, Basrai M, Staiger V, Niederberger U, Marter N, Lammert J, Grill S, Pfeifer K, Rhiem K, Schmutzler RK, Laudes M, Siniatchkin M, Halle M, Bischoff SC, Engel C.

BMC Cancer. 2017 Nov 10;17(1):752. doi: 10.1186/s12885-017-3732-4.

22.

Clinical relevance of kallikrein-related peptidase 9, 10, 11, and 15 mRNA expression in advanced high-grade serous ovarian cancer.

Geng X, Liu Y, Diersch S, Kotzsch M, Grill S, Weichert W, Kiechle M, Magdolen V, Dorn J.

PLoS One. 2017 Nov 2;12(11):e0186847. doi: 10.1371/journal.pone.0186847. eCollection 2017.

23.

Smoking and physical inactivity increase cancer prevalence in BRCA-1 and BRCA-2 mutation carriers: results from a retrospective observational analysis.

Grill S, Yahiaoui-Doktor M, Dukatz R, Lammert J, Ullrich M, Engel C, Pfeifer K, Basrai M, Siniatchkin M, Schmidt T, Weisser B, Rhiem K, Ditsch N, Schmutzler R, Bischoff SC, Halle M, Kiechle M.

Arch Gynecol Obstet. 2017 Dec;296(6):1135-1144. doi: 10.1007/s00404-017-4546-y. Epub 2017 Oct 3.

PMID:
28975393
24.

Changes of tooth color in middle and old age: A longitudinal study over a decade.

Hassel AJ, Johanning M, Grill S, Schröder J, Wahl HW, Corcodel N, Klotz AL, Rammelsberg P, Zenthöfer A.

J Esthet Restor Dent. 2017 Nov 12;29(6):459-463. doi: 10.1111/jerd.12334. Epub 2017 Aug 31.

PMID:
28858417
25.

Tylophorine Analogs Allosterically Regulates Heat Shock Cognate Protein 70 And Inhibits Hepatitis C Virus Replication.

Wang Y, Lee S, Ha Y, Lam W, Chen SR, Dutschman GE, Gullen EA, Grill SP, Cheng Y, Fürstner A, Francis S, Baker DC, Yang X, Lee KH, Cheng YC.

Sci Rep. 2017 Aug 30;7(1):10037. doi: 10.1038/s41598-017-08815-z.

26.

The mechanics of positioning skin follicles.

Grill SW.

Science. 2017 Aug 25;357(6353):750-751. doi: 10.1126/science.aao2587. Epub 2017 Aug 24. No abstract available.

PMID:
28839057
27.

Highly-Efficient Guiding of Motile Microtubules on Non-Topographical Motor Patterns.

Reuther C, Mittasch M, Naganathan SR, Grill SW, Diez S.

Nano Lett. 2017 Sep 13;17(9):5699-5705. doi: 10.1021/acs.nanolett.7b02606. Epub 2017 Aug 23.

PMID:
28819981
28.

Correction: Controlling contractile instabilities in the actomyosin cortex.

Nishikawa M, Naganathan SR, Jülicher F, Grill SW.

Elife. 2017 Jul 19;6. pii: e30537. doi: 10.7554/eLife.30537. No abstract available.

29.

How Active Mechanics and Regulatory Biochemistry Combine to Form Patterns in Development.

Gross P, Kumar KV, Grill SW.

Annu Rev Biophys. 2017 May 22;46:337-356. doi: 10.1146/annurev-biophys-070816-033602. Review.

PMID:
28532214
30.

A lentivirus-free inducible CRISPR-Cas9 system for efficient targeting of human genes.

Bisht K, Grill S, Graniel J, Nandakumar J.

Anal Biochem. 2017 Aug 1;530:40-49. doi: 10.1016/j.ab.2017.05.001. Epub 2017 May 4.

31.

Mammalian Diaphanous 1 Mediates a Pathway for E-cadherin to Stabilize Epithelial Barriers through Junctional Contractility.

Acharya BR, Wu SK, Lieu ZZ, Parton RG, Grill SW, Bershadsky AD, Gomez GA, Yap AS.

Cell Rep. 2017 Mar 21;18(12):2854-2867. doi: 10.1016/j.celrep.2017.02.078.

32.

Regional dementia care networks in Germany: changes in caregiver burden at one-year follow-up and associated factors.

Laporte Uribe F, Gräske J, Grill S, Heinrich S, Schäfer-Walkmann S, Thyrian JR, Holle B.

Int Psychogeriatr. 2017 Jun;29(6):991-1004. doi: 10.1017/S1041610217000126. Epub 2017 Mar 2.

PMID:
28249632
33.

Optical tweezers studies of transcription by eukaryotic RNA polymerases.

Lisica A, Grill SW.

Biomol Concepts. 2017 Mar 1;8(1):1-11. doi: 10.1515/bmc-2016-0028.

PMID:
28222010
34.

A bosentan pharmacokinetic study to investigate dosing regimens in paediatric patients with pulmonary arterial hypertension: FUTURE-3.

Berger RMF, Gehin M, Beghetti M, Ivy D, Kusic-Pajic A, Cornelisse P, Grill S, Bonnet D; FUTURE-3 investigators.

Br J Clin Pharmacol. 2017 Aug;83(8):1734-1744. doi: 10.1111/bcp.13267. Epub 2017 Mar 23.

35.

Controlling contractile instabilities in the actomyosin cortex.

Nishikawa M, Naganathan SR, Jülicher F, Grill SW.

Elife. 2017 Jan 28;6. pii: e19595. doi: 10.7554/eLife.19595. Erratum in: Elife. 2017 Jul 19;6:.

36.

Lifestyle intervention in BRCA1/2 mutation carriers: study protocol for a prospective, randomized, controlled clinical feasibility trial (LIBRE-1 study).

Kiechle M, Engel C, Berling A, Hebestreit K, Bischoff S, Dukatz R, Gerber WD, Siniatchkin M, Pfeifer K, Grill S, Yahiaoui-Doktor M, Kirsch E, Niederberger U, Marter N, Enders U, Löffler M, Meindl A, Rhiem K, Schmutzler R, Erickson N, Halle M.

Pilot Feasibility Stud. 2016 Dec 19;2:74. doi: 10.1186/s40814-016-0114-7. eCollection 2016.

37.

Comparison of approaches for incorporating new information into existing risk prediction models.

Grill S, Ankerst DP, Gail MH, Chatterjee N, Pfeiffer RM.

Stat Med. 2017 Mar 30;36(7):1134-1156. doi: 10.1002/sim.7190. Epub 2016 Dec 11.

PMID:
27943382
38.

Nucleosomal arrangement affects single-molecule transcription dynamics.

Fitz V, Shin J, Ehrlich C, Farnung L, Cramer P, Zaburdaev V, Grill SW.

Proc Natl Acad Sci U S A. 2016 Nov 8;113(45):12733-12738. doi: 10.1073/pnas.1602764113. Epub 2016 Oct 24.

39.

Cortical flow aligns actin filaments to form a furrow.

Reymann AC, Staniscia F, Erzberger A, Salbreux G, Grill SW.

Elife. 2016 Oct 10;5. pii: e17807. doi: 10.7554/eLife.17807.

40.

An endosomal tether undergoes an entropic collapse to bring vesicles together.

Murray DH, Jahnel M, Lauer J, Avellaneda MJ, Brouilly N, Cezanne A, Morales-Navarrete H, Perini ED, Ferguson C, Lupas AN, Kalaidzidis Y, Parton RG, Grill SW, Zerial M.

Nature. 2016 Sep 1;537(7618):107-111. doi: 10.1038/nature19326. Epub 2016 Aug 24.

41.

Predictors of free flap loss in the head and neck region: A four-year retrospective study with 451 microvascular transplants at a single centre.

Mücke T, Ritschl LM, Roth M, Güll FD, Rau A, Grill S, Kesting MR, Wolff KD, Loeffelbein DJ.

J Craniomaxillofac Surg. 2016 Sep;44(9):1292-8. doi: 10.1016/j.jcms.2016.04.029. Epub 2016 Apr 26.

PMID:
27527675
42.

Effects of lifestyle intervention in BRCA1/2 mutation carriers on nutrition, BMI, and physical fitness (LIBRE study): study protocol for a randomized controlled trial.

Kiechle M, Engel C, Berling A, Hebestreit K, Bischoff SC, Dukatz R, Siniatchkin M, Pfeifer K, Grill S, Yahiaoui-Doktor M, Kirsch E, Niederberger U, Enders U, Löffler M, Meindl A, Rhiem K, Schmutzler R, Erickson N, Halle M.

Trials. 2016 Jul 29;17:368. doi: 10.1186/s13063-016-1504-0.

43.

Stochastic resetting in backtrack recovery by RNA polymerases.

Roldán É, Lisica A, Sánchez-Taltavull D, Grill SW.

Phys Rev E. 2016 Jun;93(6):062411. doi: 10.1103/PhysRevE.93.062411. Epub 2016 Jun 20.

PMID:
27415302
44.

Influence of the sFlt-1/PlGF Ratio on Clinical Decision-Making in Women with Suspected Preeclampsia.

Klein E, Schlembach D, Ramoni A, Langer E, Bahlmann F, Grill S, Schaffenrath H, van der Does R, Messinger D, Verhagen-Kamerbeek WD, Reim M, Hund M, Stepan H.

PLoS One. 2016 May 31;11(5):e0156013. doi: 10.1371/journal.pone.0156013. eCollection 2016.

45.

A central processing sensory deficit with Parkinson's disease.

Hwang S, Agada P, Grill S, Kiemel T, Jeka JJ.

Exp Brain Res. 2016 Aug;234(8):2369-79. doi: 10.1007/s00221-016-4642-4. Epub 2016 Apr 8.

46.

Determining Physical Properties of the Cell Cortex.

Saha A, Nishikawa M, Behrndt M, Heisenberg CP, Jülicher F, Grill SW.

Biophys J. 2016 Mar 29;110(6):1421-9. doi: 10.1016/j.bpj.2016.02.013.

47.

Mechanisms of backtrack recovery by RNA polymerases I and II.

Lisica A, Engel C, Jahnel M, Roldán É, Galburt EA, Cramer P, Grill SW.

Proc Natl Acad Sci U S A. 2016 Mar 15;113(11):2946-51. doi: 10.1073/pnas.1517011113. Epub 2016 Feb 29.

48.

Actomyosin-driven left-right asymmetry: from molecular torques to chiral self organization.

Naganathan SR, Middelkoop TC, Fürthauer S, Grill SW.

Curr Opin Cell Biol. 2016 Feb;38:24-30. doi: 10.1016/j.ceb.2016.01.004. Epub 2016 Jan 30. Review.

PMID:
26829488
49.

Finasteride Reduces Risk of Bladder Cancer in a Large Prospective Screening Study.

Morales EE, Grill S, Svatek RS, Kaushik D, Thompson IM Jr, Ankerst DP, Liss MA.

Eur Urol. 2016 Mar;69(3):407-10. doi: 10.1016/j.eururo.2015.08.029. Epub 2015 Aug 28.

PMID:
26320383
50.

A Liquid-to-Solid Phase Transition of the ALS Protein FUS Accelerated by Disease Mutation.

Patel A, Lee HO, Jawerth L, Maharana S, Jahnel M, Hein MY, Stoynov S, Mahamid J, Saha S, Franzmann TM, Pozniakovski A, Poser I, Maghelli N, Royer LA, Weigert M, Myers EW, Grill S, Drechsel D, Hyman AA, Alberti S.

Cell. 2015 Aug 27;162(5):1066-77. doi: 10.1016/j.cell.2015.07.047.

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