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Items: 1 to 50 of 59

1.

Induction of Neural Crest Stem Cells From Bardet-Biedl Syndrome Patient Derived hiPSCs.

Barrell WB, Griffin JN, Harvey JL; HipSci Consortium, Danovi D, Beales P, Grigoriadis AE, Liu KJ.

Front Mol Neurosci. 2019 Jun 21;12:139. doi: 10.3389/fnmol.2019.00139. eCollection 2019.

2.

The Osteogenic Potential of the Neural Crest Lineage May Contribute to Craniosynostosis.

Doro D, Liu A, Grigoriadis AE, Liu KJ.

Mol Syndromol. 2019 Feb;10(1-2):48-57. doi: 10.1159/000493106. Epub 2018 Oct 13. Review.

3.

Hypoxia impacts human MSC response to substrate stiffness during chondrogenic differentiation.

Foyt DA, Taheem DK, Ferreira SA, Norman MDA, Petzold J, Jell G, Grigoriadis AE, Gentleman E.

Acta Biomater. 2019 Apr 15;89:73-83. doi: 10.1016/j.actbio.2019.03.002. Epub 2019 Mar 4.

4.

Murine Models of Bone Sarcomas.

Jacques C, Renema N, Ory B, Walkley CR, Grigoriadis AE, Heymann D.

Methods Mol Biol. 2019;1914:331-342. doi: 10.1007/978-1-4939-8997-3_18.

PMID:
30729474
5.

Author Correction: Bi-directional cell-pericellular matrix interactions direct stem cell fate.

Ferreira SA, Motwani MS, Faull PA, Seymour AJ, Yu TTL, Enayati M, Taheem DK, Salzlechner C, Haghighi T, Kania EM, Oommen OP, Ahmed T, Loaiza S, Parzych K, Dazzi F, Varghese OP, Festy F, Grigoriadis AE, Auner HW, Snijders AP, Bozec L, Gentleman E.

Nat Commun. 2018 Dec 18;9(1):5419. doi: 10.1038/s41467-018-07843-1.

6.

G-Alpha Subunit Abundance and Activity Differentially Regulate β-Catenin Signaling.

Banu A, Liu KJ, Lax AJ, Grigoriadis AE.

Mol Cell Biol. 2019 Feb 15;39(5). pii: e00422-18. doi: 10.1128/MCB.00422-18. Print 2019 Mar 1.

7.

Author Correction: Bi-directional cell-pericellular matrix interactions direct stem cell fate.

Ferreira SA, Motwani MS, Faull PA, Seymour AJ, Yu TTL, Enayati M, Taheem DK, Salzlechner C, Haghighi T, Kania EM, Oommen OP, Ahmed T, Loaiza S, Parzych K, Dazzi F, Varghese OP, Festy F, Grigoriadis AE, Auner HW, Snijders AP, Bozec L, Gentleman E.

Nat Commun. 2018 Nov 14;9(1):4851. doi: 10.1038/s41467-018-07398-1.

8.

Bi-directional cell-pericellular matrix interactions direct stem cell fate.

Ferreira SA, Motwani MS, Faull PA, Seymour AJ, Yu TTL, Enayati M, Taheem DK, Salzlechner C, Haghighi T, Kania EM, Oommen OP, Ahmed T, Loaiza S, Parzych K, Dazzi F, Varghese OP, Festy F, Grigoriadis AE, Auner HW, Snijders AP, Bozec L, Gentleman E.

Nat Commun. 2018 Oct 3;9(1):4049. doi: 10.1038/s41467-018-06183-4. Erratum in: Nat Commun. 2018 Nov 14;9(1):4851. Nat Commun. 2018 Dec 18;9(1):5419.

9.

Site-specific differences in osteoblast phenotype, mechanical loading response and estrogen receptor-related gene expression.

Gharibi B, Ghuman MS, Cama G, Rawlinson SCF, Grigoriadis AE, Hughes FJ.

Mol Cell Endocrinol. 2018 Dec 5;477:140-147. doi: 10.1016/j.mce.2018.06.011. Epub 2018 Jun 19.

PMID:
29928929
10.

Recurrent rearrangements of FOS and FOSB define osteoblastoma.

Fittall MW, Mifsud W, Pillay N, Ye H, Strobl AC, Verfaillie A, Demeulemeester J, Zhang L, Berisha F, Tarabichi M, Young MD, Miranda E, Tarpey PS, Tirabosco R, Amary F, Grigoriadis AE, Stratton MR, Van Loo P, Antonescu CR, Campbell PJ, Flanagan AM, Behjati S.

Nat Commun. 2018 Jun 1;9(1):2150. doi: 10.1038/s41467-018-04530-z.

11.

Small animal models for the study of bone sarcoma pathogenesis:characteristics, therapeutic interests and limitations.

Jacques C, Renema N, Lezot F, Ory B, Walkley CR, Grigoriadis AE, Heymann D.

J Bone Oncol. 2018 Feb 21;12:7-13. doi: 10.1016/j.jbo.2018.02.004. eCollection 2018 Sep. Review.

12.

Differential Regulation of Human Bone Marrow Mesenchymal Stromal Cell Chondrogenesis by Hypoxia Inducible Factor-1α Hydroxylase Inhibitors.

Taheem DK, Foyt DA, Loaiza S, Ferreira SA, Ilic D, Auner HW, Grigoriadis AE, Jell G, Gentleman E.

Stem Cells. 2018 Sep;36(9):1380-1392. doi: 10.1002/stem.2844. Epub 2018 Jun 8.

13.

Calvarial Suture-Derived Stem Cells and Their Contribution to Cranial Bone Repair.

Doro DH, Grigoriadis AE, Liu KJ.

Front Physiol. 2017 Nov 27;8:956. doi: 10.3389/fphys.2017.00956. eCollection 2017. Review.

14.

Regulation of osteosarcoma cell lung metastasis by the c-Fos/AP-1 target FGFR1.

Weekes D, Kashima TG, Zandueta C, Perurena N, Thomas DP, Sunters A, Vuillier C, Bozec A, El-Emir E, Miletich I, Patiño-Garcia A, Lecanda F, Grigoriadis AE.

Oncogene. 2016 Jun 2;35(22):2948. doi: 10.1038/onc.2015.420. No abstract available.

PMID:
27251742
15.

Matrix-Gla protein promotes osteosarcoma lung metastasis and associates with poor prognosis.

Zandueta C, Ormazábal C, Perurena N, Martínez-Canarias S, Zalacaín M, Julián MS, Grigoriadis AE, Valencia K, Campos-Laborie FJ, Rivas Jde L, Vicent S, Patiño-García A, Lecanda F.

J Pathol. 2016 Aug;239(4):438-49. doi: 10.1002/path.4740. Epub 2016 Jun 29.

PMID:
27172275
16.

Small Molecule Inhibition of Transforming Growth Factor Beta Signaling Enables the Endogenous Regenerative Potential of the Mammalian Calvarium.

Senarath-Yapa K, Li S, Walmsley GG, Zielins E, Paik K, Britto JA, Grigoriadis AE, Wan DC, Liu KJ, Longaker MT, Quarto N.

Tissue Eng Part A. 2016 May;22(9-10):707-20. doi: 10.1089/ten.TEA.2015.0527. Epub 2016 Apr 26.

17.

Root and Eruption Defects in c-Fos Mice Are Driven by Loss of Osteoclasts.

Alfaqeeh S, Oralova V, Foxworthy M, Matalova E, Grigoriadis AE, Tucker AS.

J Dent Res. 2015 Dec;94(12):1724-31. doi: 10.1177/0022034515608828. Epub 2015 Oct 6.

PMID:
26442949
18.

Regulation of osteosarcoma cell lung metastasis by the c-Fos/AP-1 target FGFR1.

Weekes D, Kashima TG, Zandueta C, Perurena N, Thomas DP, Sunters A, Vuillier C, Bozec A, El-Emir E, Miletich I, Patiño-Garcia A, Lecanda F, Grigoriadis AE.

Oncogene. 2016 Jun 2;35(22):2852-61. doi: 10.1038/onc.2015.344. Epub 2015 Sep 21. Erratum in: Oncogene. 2016 Jun 2;35(22):2948.

19.

Specification of chondrocytes and cartilage tissues from embryonic stem cells.

Craft AM, Ahmed N, Rockel JS, Baht GS, Alman BA, Kandel RA, Grigoriadis AE, Keller GM.

Development. 2013 Jun;140(12):2597-610. doi: 10.1242/dev.087890.

20.

A specific role for phosphoinositide 3-kinase and AKT in osteoblasts?

McGonnell IM, Grigoriadis AE, Lam EW, Price JS, Sunters A.

Front Endocrinol (Lausanne). 2012 Jul 20;3:88. doi: 10.3389/fendo.2012.00088. eCollection 2012.

21.

Podoplanin is regulated by AP-1 and promotes platelet aggregation and cell migration in osteosarcoma.

Kunita A, Kashima TG, Ohazama A, Grigoriadis AE, Fukayama M.

Am J Pathol. 2011 Aug;179(2):1041-9. doi: 10.1016/j.ajpath.2011.04.027. Epub 2011 Jun 12.

22.

Mesenchymal differentiation propensity of a human embryonic stem cell line.

Pringle S, De Bari C, Dell'Accio F, Przyborski S, Cooke MJ, Minger SL, Grigoriadis AE.

Cell Prolif. 2011 Apr;44(2):120-7. doi: 10.1111/j.1365-2184.2011.00744.x.

PMID:
21401753
23.

Stable knockdown of S100A4 suppresses cell migration and metastasis of osteosarcoma.

Fujiwara M, Kashima TG, Kunita A, Kii I, Komura D, Grigoriadis AE, Kudo A, Aburatani H, Fukayama M.

Tumour Biol. 2011 Jun;32(3):611-22. doi: 10.1007/s13277-011-0160-y. Epub 2011 Mar 1.

PMID:
21360024
24.

Neighbor of Brca1 gene (Nbr1) functions as a negative regulator of postnatal osteoblastic bone formation and p38 MAPK activity.

Whitehouse CA, Waters S, Marchbank K, Horner A, McGowan NW, Jovanovic JV, Xavier GM, Kashima TG, Cobourne MT, Richards GO, Sharpe PT, Skerry TM, Grigoriadis AE, Solomon E.

Proc Natl Acad Sci U S A. 2010 Jul 20;107(29):12913-8. doi: 10.1073/pnas.0913058107. Epub 2010 Jun 29. Erratum in: Proc Natl Acad Sci U S A. 2013 Mar 12;110(11):4428.

25.

A distinct spectrum of copy number aberrations in pediatric high-grade gliomas.

Bax DA, Mackay A, Little SE, Carvalho D, Viana-Pereira M, Tamber N, Grigoriadis AE, Ashworth A, Reis RM, Ellison DW, Al-Sarraj S, Hargrave D, Jones C.

Clin Cancer Res. 2010 Jul 1;16(13):3368-77. doi: 10.1158/1078-0432.CCR-10-0438. Epub 2010 Jun 22.

26.

Dlx homeobox gene family expression in osteoclasts.

Lézot F, Thomas BL, Blin-Wakkach C, Castaneda B, Bolanos A, Hotton D, Sharpe PT, Heymann D, Carles GF, Grigoriadis AE, Berdal A.

J Cell Physiol. 2010 Jun;223(3):779-87. doi: 10.1002/jcp.22095.

PMID:
20205208
27.

Directed differentiation of hematopoietic precursors and functional osteoclasts from human ES and iPS cells.

Grigoriadis AE, Kennedy M, Bozec A, Brunton F, Stenbeck G, Park IH, Wagner EF, Keller GM.

Blood. 2010 Apr 8;115(14):2769-76. doi: 10.1182/blood-2009-07-234690. Epub 2010 Jan 11.

28.

Periostin, a novel marker of intramembranous ossification, is expressed in fibrous dysplasia and in c-Fos-overexpressing bone lesions.

Kashima TG, Nishiyama T, Shimazu K, Shimazaki M, Kii I, Grigoriadis AE, Fukayama M, Kudo A.

Hum Pathol. 2009 Feb;40(2):226-37. doi: 10.1016/j.humpath.2008.07.008. Epub 2008 Sep 16.

PMID:
18799196
29.

A role for GATA-6 in vertebrate chondrogenesis.

Alexandrovich A, Qureishi A, Coudert AE, Zhang L, Grigoriadis AE, Shah AM, Brewer AC, Pizzey JA.

Dev Biol. 2008 Feb 15;314(2):457-70. doi: 10.1016/j.ydbio.2007.12.001. Epub 2007 Dec 8.

30.

Cell fate specification during calvarial bone and suture development.

Lana-Elola E, Rice R, Grigoriadis AE, Rice DP.

Dev Biol. 2007 Nov 15;311(2):335-46. Epub 2007 Sep 14.

31.

[Effect of TNF-alpha on murine osteoclast differentiation].

Zhao YM, Ge LH, Grigoriadis AE.

Beijing Da Xue Xue Bao Yi Xue Ban. 2005 Aug 18;37(4):433-5. Chinese.

32.

Changes in RANKL/OPG/RANK gene expression in peripheral mononuclear cells following treatment with estrogen or raloxifene.

Bashir A, Mak YT, Sankaralingam S, Cheung J, McGowan NW, Grigoriadis AE, Fogelman I, Hampson G.

Steroids. 2005 Dec 1;70(13):847-55. Epub 2005 Jul 7.

PMID:
16005483
33.

The pasteurella multocida toxin interacts with signalling pathways to perturb cell growth and differentiation.

Lax AJ, Pullinger GD, Baldwin MR, Harmey D, Grigoriadis AE, Lakey JH.

Int J Med Microbiol. 2004 Apr;293(7-8):505-12. Review.

PMID:
15149025
34.

Regulation of osteoblast differentiation by Pasteurella multocida toxin (PMT): a role for Rho GTPase in bone formation.

Harmey D, Stenbeck G, Nobes CD, Lax AJ, Grigoriadis AE.

J Bone Miner Res. 2004 Apr;19(4):661-70. Epub 2004 Jan 5.

35.

Accelerated cell cycle progression in osteoblasts overexpressing the c-fos proto-oncogene: induction of cyclin A and enhanced CDK2 activity.

Sunters A, Thomas DP, Yeudall WA, Grigoriadis AE.

J Biol Chem. 2004 Mar 12;279(11):9882-91. Epub 2003 Dec 29.

36.

Overexpression of cadherins suppresses pulmonary metastasis of osteosarcoma in vivo.

Kashima T, Nakamura K, Kawaguchi J, Takanashi M, Ishida T, Aburatani H, Kudo A, Fukayama M, Grigoriadis AE.

Int J Cancer. 2003 Mar 20;104(2):147-54.

37.

Expression of collagenase-3 (MMP-13) in c-fos-induced osteosarcomas and chondrosarcomas is restricted to a subset of cells of the osteo-/chondrogenic lineage.

Tuckermann JP, Vallon R, Gack S, Grigoriadis AE, Porte D, Lutz A, Wagner EF, Schmidt J, Angel P.

Differentiation. 2001 Dec;69(1):49-57.

PMID:
11776394
38.
39.

Inhibition of chondrocyte differentiation in vitro by constitutive and inducible overexpression of the c-fos proto-oncogene.

Thomas DP, Sunters A, Gentry A, Grigoriadis AE.

J Cell Sci. 2000 Feb;113 ( Pt 3):439-50.

40.

A putative role for c-Fos in the pathophysiology of Paget's disease.

Beedles KE, Sharpe PT, Wagner EF, Grigoriadis AE.

J Bone Miner Res. 1999 Oct;14 Suppl 2:21-8.

PMID:
10510209
41.

Control of cell cycle gene expression in bone development and during c-Fos-induced osteosarcoma formation.

Sunters A, McCluskey J, Grigoriadis AE.

Dev Genet. 1998;22(4):386-97.

PMID:
9664690
42.

Embryonic overexpression of the c-Fos protooncogene. A murine stem cell chimera applicable to the study of fibrodysplasia ossificans progressiva in humans.

Olmsted EA, Gannon FH, Wang ZQ, Grigoriadis AE, Wagner EF, Zasloff MA, Shore EM, Kaplan FS.

Clin Orthop Relat Res. 1998 Jan;(346):81-94.

PMID:
9577414
43.
44.

c-fos-induced osteosarcoma formation in transgenic mice: cooperativity with c-jun and the role of endogenous c-fos.

Wang ZQ, Liang J, Schellander K, Wagner EF, Grigoriadis AE.

Cancer Res. 1995 Dec 15;55(24):6244-51.

45.

Fos and bone cell development: lessons from a nuclear oncogene.

Grigoriadis AE, Wang ZQ, Wagner EF.

Trends Genet. 1995 Nov;11(11):436-41. Review.

PMID:
8578600
46.

c-Fos: a key regulator of osteoclast-macrophage lineage determination and bone remodeling.

Grigoriadis AE, Wang ZQ, Cecchini MG, Hofstetter W, Felix R, Fleisch HA, Wagner EF.

Science. 1994 Oct 21;266(5184):443-8.

PMID:
7939685
47.
48.

Osteoblasts are target cells for transformation in c-fos transgenic mice.

Grigoriadis AE, Schellander K, Wang ZQ, Wagner EF.

J Cell Biol. 1993 Aug;122(3):685-701.

49.

Stable murine chondrogenic cell lines derived from c-fos-induced cartilage tumors.

Wang ZQ, Grigoriadis AE, Wagner EF.

J Bone Miner Res. 1993 Jul;8(7):839-47.

PMID:
7688930
50.

Bone and haematopoietic defects in mice lacking c-fos.

Wang ZQ, Ovitt C, Grigoriadis AE, Möhle-Steinlein U, Rüther U, Wagner EF.

Nature. 1992 Dec 24-31;360(6406):741-5.

PMID:
1465144

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