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Items: 1 to 50 of 148

1.

Metabolic profiles to predict long-term cancer and mortality: the use of latent class analysis.

Santaolalla A, Garmo H, Grigoriadis A, Ghuman S, Hammar N, Jungner I, Walldius G, Lambe M, Holmberg L, Van Hemelrijck M.

BMC Mol Cell Biol. 2019 Jul 23;20(1):28. doi: 10.1186/s12860-019-0210-7.

2.

Induction of Neural Crest Stem Cells From Bardet-Biedl Syndrome Patient Derived hiPSCs.

Barrell WB, Griffin JN, Harvey JL; HipSci Consortium, Danovi D, Beales P, Grigoriadis AE, Liu KJ.

Front Mol Neurosci. 2019 Jun 21;12:139. doi: 10.3389/fnmol.2019.00139. eCollection 2019.

3.

Integrin-Mediated Macrophage Adhesion Promotes Lymphovascular Dissemination in Breast Cancer.

Evans R, Flores-Borja F, Nassiri S, Miranda E, Lawler K, Grigoriadis A, Monypenny J, Gillet C, Owen J, Gordon P, Male V, Cheung A, Noor F, Barber P, Marlow R, Francesch-Domenech E, Fruhwirth G, Squadrito M, Vojnovic B, Tutt A, Festy F, De Palma M, Ng T.

Cell Rep. 2019 May 14;27(7):1967-1978.e4. doi: 10.1016/j.celrep.2019.04.076.

4.

The Osteogenic Potential of the Neural Crest Lineage May Contribute to Craniosynostosis.

Doro D, Liu A, Grigoriadis AE, Liu KJ.

Mol Syndromol. 2019 Feb;10(1-2):48-57. doi: 10.1159/000493106. Epub 2018 Oct 13. Review.

5.

Hypoxia impacts human MSC response to substrate stiffness during chondrogenic differentiation.

Foyt DA, Taheem DK, Ferreira SA, Norman MDA, Petzold J, Jell G, Grigoriadis AE, Gentleman E.

Acta Biomater. 2019 Apr 15;89:73-83. doi: 10.1016/j.actbio.2019.03.002. Epub 2019 Mar 4.

6.

Vibratory stimulus to the masseter muscle impairs the oral fine motor control during biting tasks.

Kumar A, Tanaka Y, Takahashi K, Grigoriadis A, Wiesinger B, Svensson P, Trulsson M.

J Prosthodont Res. 2019 Jul;63(3):354-360. doi: 10.1016/j.jpor.2018.10.011. Epub 2019 Mar 2.

PMID:
30833186
7.

Murine Models of Bone Sarcomas.

Jacques C, Renema N, Ory B, Walkley CR, Grigoriadis AE, Heymann D.

Methods Mol Biol. 2019;1914:331-342. doi: 10.1007/978-1-4939-8997-3_18.

PMID:
30729474
8.

Pan-cancer transcriptomic analysis dissects immune and proliferative functions of APOBEC3 cytidine deaminases.

Ng JCF, Quist J, Grigoriadis A, Malim MH, Fraternali F.

Nucleic Acids Res. 2019 Feb 20;47(3):1178-1194. doi: 10.1093/nar/gky1316.

9.

Dual Mechanisms of LYN Kinase Dysregulation Drive Aggressive Behavior in Breast Cancer Cells.

Tornillo G, Knowlson C, Kendrick H, Cooke J, Mirza H, Aurrekoetxea-Rodríguez I, Vivanco MDM, Buckley NE, Grigoriadis A, Smalley MJ.

Cell Rep. 2018 Dec 26;25(13):3674-3692.e10. doi: 10.1016/j.celrep.2018.11.103.

10.

Author Correction: Bi-directional cell-pericellular matrix interactions direct stem cell fate.

Ferreira SA, Motwani MS, Faull PA, Seymour AJ, Yu TTL, Enayati M, Taheem DK, Salzlechner C, Haghighi T, Kania EM, Oommen OP, Ahmed T, Loaiza S, Parzych K, Dazzi F, Varghese OP, Festy F, Grigoriadis AE, Auner HW, Snijders AP, Bozec L, Gentleman E.

Nat Commun. 2018 Dec 18;9(1):5419. doi: 10.1038/s41467-018-07843-1.

11.

G-Alpha Subunit Abundance and Activity Differentially Regulate β-Catenin Signaling.

Banu A, Liu KJ, Lax AJ, Grigoriadis AE.

Mol Cell Biol. 2019 Feb 15;39(5). pii: e00422-18. doi: 10.1128/MCB.00422-18. Print 2019 Mar 1.

12.

Molecular patterns of cancer colonisation in lymph nodes of breast cancer patients.

Chatterjee G, Pai T, Hardiman T, Avery-Kiejda K, Scott RJ, Spencer J, Pinder SE, Grigoriadis A.

Breast Cancer Res. 2018 Nov 20;20(1):143. doi: 10.1186/s13058-018-1070-3. Review.

13.

Author Correction: Bi-directional cell-pericellular matrix interactions direct stem cell fate.

Ferreira SA, Motwani MS, Faull PA, Seymour AJ, Yu TTL, Enayati M, Taheem DK, Salzlechner C, Haghighi T, Kania EM, Oommen OP, Ahmed T, Loaiza S, Parzych K, Dazzi F, Varghese OP, Festy F, Grigoriadis AE, Auner HW, Snijders AP, Bozec L, Gentleman E.

Nat Commun. 2018 Nov 14;9(1):4851. doi: 10.1038/s41467-018-07398-1.

14.

A Four-gene Decision Tree Signature Classification of Triple-negative Breast Cancer: Implications for Targeted Therapeutics.

Quist J, Mirza H, Cheang MCU, Telli ML, O'Shaughnessy JA, Lord CJ, Tutt ANJ, Grigoriadis A.

Mol Cancer Ther. 2019 Jan;18(1):204-212. doi: 10.1158/1535-7163.MCT-18-0243. Epub 2018 Oct 10.

15.

Bi-directional cell-pericellular matrix interactions direct stem cell fate.

Ferreira SA, Motwani MS, Faull PA, Seymour AJ, Yu TTL, Enayati M, Taheem DK, Salzlechner C, Haghighi T, Kania EM, Oommen OP, Ahmed T, Loaiza S, Parzych K, Dazzi F, Varghese OP, Festy F, Grigoriadis AE, Auner HW, Snijders AP, Bozec L, Gentleman E.

Nat Commun. 2018 Oct 3;9(1):4049. doi: 10.1038/s41467-018-06183-4. Erratum in: Nat Commun. 2018 Nov 14;9(1):4851. Nat Commun. 2018 Dec 18;9(1):5419.

16.

Recommendations on the Use of Magnetic Resonance Imaging for Collaborative Multicenter Studies in Primary Sclerosing Cholangitis.

Ringe KI, Grigoriadis A, Halibasic E, Wacker F, Manns MP, Schramm C, Lenzen H; MRI working group of the IPSCSG.

Hepatology. 2019 Mar;69(3):1358-1359. doi: 10.1002/hep.30276. Epub 2019 Feb 23. No abstract available.

PMID:
30222864
17.

Anti-Folate Receptor Alpha-Directed Antibody Therapies Restrict the Growth of Triple-negative Breast Cancer.

Cheung A, Opzoomer J, Ilieva KM, Gazinska P, Hoffmann RM, Mirza H, Marlow R, Francesch-Domenech E, Fittall M, Dominguez Rodriguez D, Clifford A, Badder L, Patel N, Mele S, Pellizzari G, Bax HJ, Crescioli S, Petranyi G, Larcombe-Young D, Josephs DH, Canevari S, Figini M, Pinder S, Nestle FO, Gillett C, Spicer JF, Grigoriadis A, Tutt ANJ, Karagiannis SN.

Clin Cancer Res. 2018 Oct 15;24(20):5098-5111. doi: 10.1158/1078-0432.CCR-18-0652. Epub 2018 Aug 1.

18.

Development of the jaw sensorimotor control and chewing - a systematic review.

Almotairy N, Kumar A, Trulsson M, Grigoriadis A.

Physiol Behav. 2018 Oct 1;194:456-465. doi: 10.1016/j.physbeh.2018.06.037. Epub 2018 Jun 28.

PMID:
29960013
19.

Site-specific differences in osteoblast phenotype, mechanical loading response and estrogen receptor-related gene expression.

Gharibi B, Ghuman MS, Cama G, Rawlinson SCF, Grigoriadis AE, Hughes FJ.

Mol Cell Endocrinol. 2018 Dec 5;477:140-147. doi: 10.1016/j.mce.2018.06.011. Epub 2018 Jun 19.

PMID:
29928929
20.

Excitatory drive of masseter muscle during mastication with dental implants.

Grigoriadis A, Trulsson M.

Sci Rep. 2018 Jun 5;8(1):8597. doi: 10.1038/s41598-018-26926-z.

21.

Recurrent rearrangements of FOS and FOSB define osteoblastoma.

Fittall MW, Mifsud W, Pillay N, Ye H, Strobl AC, Verfaillie A, Demeulemeester J, Zhang L, Berisha F, Tarabichi M, Young MD, Miranda E, Tarpey PS, Tirabosco R, Amary F, Grigoriadis AE, Stratton MR, Van Loo P, Antonescu CR, Campbell PJ, Flanagan AM, Behjati S.

Nat Commun. 2018 Jun 1;9(1):2150. doi: 10.1038/s41467-018-04530-z.

22.

Small animal models for the study of bone sarcoma pathogenesis:characteristics, therapeutic interests and limitations.

Jacques C, Renema N, Lezot F, Ory B, Walkley CR, Grigoriadis AE, Heymann D.

J Bone Oncol. 2018 Feb 21;12:7-13. doi: 10.1016/j.jbo.2018.02.004. eCollection 2018 Sep. Review.

23.

Differential Regulation of Human Bone Marrow Mesenchymal Stromal Cell Chondrogenesis by Hypoxia Inducible Factor-1α Hydroxylase Inhibitors.

Taheem DK, Foyt DA, Loaiza S, Ferreira SA, Ilic D, Auner HW, Grigoriadis AE, Jell G, Gentleman E.

Stem Cells. 2018 Sep;36(9):1380-1392. doi: 10.1002/stem.2844. Epub 2018 Jun 8.

24.

Carboplatin in BRCA1/2-mutated and triple-negative breast cancer BRCAness subgroups: the TNT Trial.

Tutt A, Tovey H, Cheang MCU, Kernaghan S, Kilburn L, Gazinska P, Owen J, Abraham J, Barrett S, Barrett-Lee P, Brown R, Chan S, Dowsett M, Flanagan JM, Fox L, Grigoriadis A, Gutin A, Harper-Wynne C, Hatton MQ, Hoadley KA, Parikh J, Parker P, Perou CM, Roylance R, Shah V, Shaw A, Smith IE, Timms KM, Wardley AM, Wilson G, Gillett C, Lanchbury JS, Ashworth A, Rahman N, Harries M, Ellis P, Pinder SE, Bliss JM.

Nat Med. 2018 May;24(5):628-637. doi: 10.1038/s41591-018-0009-7. Epub 2018 Apr 30.

25.

Systematic identification of functionally relevant risk alleles to stratify aggressive versus indolent prostate cancer.

Nowinski S, Santaolalla A, O'Leary B, Loda M, Mirchandani A, Emberton M, Van Hemelrijck M, Grigoriadis A.

Oncotarget. 2018 Feb 5;9(16):12812-12824. doi: 10.18632/oncotarget.24400. eCollection 2018 Feb 27.

26.

Integrated genomics and functional validation identifies malignant cell specific dependencies in triple negative breast cancer.

Patel N, Weekes D, Drosopoulos K, Gazinska P, Noel E, Rashid M, Mirza H, Quist J, Brasó-Maristany F, Mathew S, Ferro R, Pereira AM, Prince C, Noor F, Francesch-Domenech E, Marlow R, de Rinaldis E, Grigoriadis A, Linardopoulos S, Marra P, Tutt ANJ.

Nat Commun. 2018 Mar 13;9(1):1044. doi: 10.1038/s41467-018-03283-z.

27.

An RNAi screen of Rho signalling networks identifies RhoH as a regulator of Rac1 in prostate cancer cell migration.

Tajadura-Ortega V, Garg R, Allen R, Owczarek C, Bright MD, Kean S, Mohd-Noor A, Grigoriadis A, Elston TC, Hahn KM, Ridley AJ.

BMC Biol. 2018 Mar 6;16(1):29. doi: 10.1186/s12915-018-0489-4.

28.

Histological scoring of immune and stromal features in breast and axillary lymph nodes is prognostic for distant metastasis in lymph node-positive breast cancers.

Grigoriadis A, Gazinska P, Pai T, Irhsad S, Wu Y, Millis R, Naidoo K, Owen J, Gillett CE, Tutt A, Coolen AC, Pinder SE.

J Pathol Clin Res. 2018 Jan 8;4(1):39-54. doi: 10.1002/cjp2.87. eCollection 2018 Jan.

29.

Repurposing Tin Mesoporphyrin as an Immune Checkpoint Inhibitor Shows Therapeutic Efficacy in Preclinical Models of Cancer.

Muliaditan T, Opzoomer JW, Caron J, Okesola M, Kosti P, Lall S, Van Hemelrijck M, Dazzi F, Tutt A, Grigoriadis A, Gillett CE, Madden SF, Burchell JM, Kordasti S, Diebold SS, Spicer JF, Arnold JN.

Clin Cancer Res. 2018 Apr 1;24(7):1617-1628. doi: 10.1158/1078-0432.CCR-17-2587. Epub 2018 Jan 16.

30.

Bite or brain: Implication of sensorimotor regulation and neuroplasticity in oral rehabilitation procedures.

Kumar A, Kothari M, Grigoriadis A, Trulsson M, Svensson P.

J Oral Rehabil. 2018 Apr;45(4):323-333. doi: 10.1111/joor.12603. Epub 2018 Jan 18. Review.

PMID:
29314189
31.

Calvarial Suture-Derived Stem Cells and Their Contribution to Cranial Bone Repair.

Doro DH, Grigoriadis AE, Liu KJ.

Front Physiol. 2017 Nov 27;8:956. doi: 10.3389/fphys.2017.00956. eCollection 2017. Review.

32.

Evaluation of CDK12 Protein Expression as a Potential Novel Biomarker for DNA Damage Response-Targeted Therapies in Breast Cancer.

Naidoo K, Wai PT, Maguire SL, Daley F, Haider S, Kriplani D, Campbell J, Mirza H, Grigoriadis A, Tutt A, Moseley PM, Abdel-Fatah TMA, Chan SYT, Madhusudan S, Rhaka EA, Ellis IO, Lord CJ, Yuan Y, Green AR, Natrajan R.

Mol Cancer Ther. 2018 Jan;17(1):306-315. doi: 10.1158/1535-7163.MCT-17-0760. Epub 2017 Nov 13.

33.

Gene expression modules in primary breast cancers as risk factors for organotropic patterns of first metastatic spread: a case control study.

Lawler K, Papouli E, Naceur-Lombardelli C, Mera A, Ougham K, Tutt A, Kimbung S, Hedenfalk I, Zhan J, Zhang H, Buus R, Dowsett M, Ng T, Pinder SE, Parker P, Holmberg L, Gillett CE, Grigoriadis A, Purushotham A.

Breast Cancer Res. 2017 Oct 13;19(1):113. doi: 10.1186/s13058-017-0881-y.

34.

Utility of VS38c in the diagnostic and prognostic assessment of osteosarcoma and other bone tumours/tumour-like lesions.

Hookway ES, Orosz Z, Uchihara Y, Grigoriadis A, Hassan AB, Oppermann U, Athanasou NA.

Clin Sarcoma Res. 2017 Sep 18;7:17. doi: 10.1186/s13569-017-0083-5. eCollection 2017.

35.

Training-induced dynamics of accuracy and precision in human motor control.

Kumar A, Tanaka Y, Grigoriadis A, Grigoriadis J, Trulsson M, Svensson P.

Sci Rep. 2017 Jul 28;7(1):6784. doi: 10.1038/s41598-017-07078-y.

36.

Erratum: PIM1 kinase regulates cell death, tumor growth and chemotherapy response in triple-negative breast cancer.

Brasó-Maristany F, Filosto S, Catchpole S, Marlow R, Quist J, Francesch-Domenech E, Plumb DA, Zakka L, Gazinska P, Liccardi G, Meier P, Gris-Oliver A, Cheang MCU, Perdrix-Rosell A, Shafat M, Noël E, Patel N, McEachern K, Scaltriti M, Castel P, Noor F, Buus R, Mathew S, Watkins J, Serra V, Marra P, Grigoriadis A, Tutt AN.

Nat Med. 2017 Jun 6;23(6):788. doi: 10.1038/nm0617-788b. No abstract available.

PMID:
28586336
37.

Erratum: PIM1 kinase regulates cell death, tumor growth and chemotherapy response in triple-negative breast cancer.

Brasó-Maristany F, Filosto S, Catchpole S, Marlow R, Quist J, Francesch-Domenech E, Plumb DA, Zakka L, Gazinska P, Liccardi G, Meier P, Gris-Oliver A, Cheang MC, Perdrix-Rosell A, Shafat M, Noël E, Patel N, McEachern K, Scaltriti M, Castel P, Noor F, Buus R, Mathew S, Watkins J, Serra V, Marra P, Grigoriadis A, Tutt AN.

Nat Med. 2017 Apr 7;23(4):526. doi: 10.1038/nm0417-526c. No abstract available.

PMID:
28388604
38.

Erratum to: Outcomes of implant therapy in patients with a history of aggressive periodontitis. A systematic review and meta-analysis.

Theodoridis C, Grigoriadis A, Menexes G, Vouros I.

Clin Oral Investig. 2017 Apr;21(3):965. doi: 10.1007/s00784-017-2060-z. No abstract available.

PMID:
28181073
39.

PIK3CA mutations are common in lobular carcinoma in situ, but are not a biomarker of progression.

Shah V, Nowinski S, Levi D, Shinomiya I, Kebaier Ep Chaabouni N, Gillett C, Grigoriadis A, Graham TA, Roylance R, Simpson MA, Pinder SE, Sawyer EJ.

Breast Cancer Res. 2017 Jan 17;19(1):7. doi: 10.1186/s13058-016-0789-y.

40.

RORγt+ Innate Lymphoid Cells Promote Lymph Node Metastasis of Breast Cancers.

Irshad S, Flores-Borja F, Lawler K, Monypenny J, Evans R, Male V, Gordon P, Cheung A, Gazinska P, Noor F, Wong F, Grigoriadis A, Fruhwirth GO, Barber PR, Woodman N, Patel D, Rodriguez-Justo M, Owen J, Martin SG, Pinder SE, Gillett CE, Poland SP, Ameer-Beg S, McCaughan F, Carlin LM, Hasan U, Withers DR, Lane P, Vojnovic B, Quezada SA, Ellis P, Tutt AN, Ng T.

Cancer Res. 2017 Mar 1;77(5):1083-1096. doi: 10.1158/0008-5472.CAN-16-0598. Epub 2017 Jan 12.

41.

Splicing imbalances in basal-like breast cancer underpin perturbation of cell surface and oncogenic pathways and are associated with patients' survival.

Gracio F, Burford B, Gazinska P, Mera A, Mohd Noor A, Marra P, Gillett C, Grigoriadis A, Pinder S, Tutt A, de Rinaldis E.

Sci Rep. 2017 Jan 6;7:40177. doi: 10.1038/srep40177.

42.

Outcomes of implant therapy in patients with a history of aggressive periodontitis. A systematic review and meta-analysis.

Theodoridis C, Grigoriadis A, Menexes G, Vouros I.

Clin Oral Investig. 2017 Mar;21(2):485-503. doi: 10.1007/s00784-016-2026-6. Epub 2016 Dec 24. Review. Erratum in: Clin Oral Investig. 2017 Apr;21(3):965.

PMID:
28013438
43.

Functional and prognostic significance of the genomic amplification of frizzled 6 (FZD6) in breast cancer.

Corda G, Sala G, Lattanzio R, Iezzi M, Sallese M, Fragassi G, Lamolinara A, Mirza H, Barcaroli D, Ermler S, Silva E, Yasaei H, Newbold RF, Vagnarelli P, Mottolese M, Natali PG, Perracchio L, Quist J, Grigoriadis A, Marra P, Tutt AN, Piantelli M, Iacobelli S, De Laurenzi V, Sala A.

J Pathol. 2017 Feb;241(3):350-361. doi: 10.1002/path.4841. Epub 2016 Dec 29.

44.

PIM1 kinase regulates cell death, tumor growth and chemotherapy response in triple-negative breast cancer.

Brasó-Maristany F, Filosto S, Catchpole S, Marlow R, Quist J, Francesch-Domenech E, Plumb DA, Zakka L, Gazinska P, Liccardi G, Meier P, Gris-Oliver A, Cheang MC, Perdrix-Rosell A, Shafat M, Noël E, Patel N, McEachern K, Scaltriti M, Castel P, Noor F, Buus R, Mathew S, Watkins J, Serra V, Marra P, Grigoriadis A, Tutt AN.

Nat Med. 2016 Nov;22(11):1303-1313. doi: 10.1038/nm.4198. Epub 2016 Oct 24. Erratum in: Nat Med. 2017 Apr 7;23 (4):526. Nat Med. 2017 Jun 6;23 (6):788.

45.

Functional redundancy between Apc and Apc2 regulates tissue homeostasis and prevents tumorigenesis in murine mammary epithelium.

Daly CS, Shaw P, Ordonez LD, Williams GT, Quist J, Grigoriadis A, Van Es JH, Clevers H, Clarke AR, Reed KR.

Oncogene. 2017 Mar 30;36(13):1793-1803. doi: 10.1038/onc.2016.342. Epub 2016 Oct 3.

46.

Tandem duplications contribute to not one but two distinct phenotypes.

Watkins J, Tutt A, Grigoriadis A.

Proc Natl Acad Sci U S A. 2016 Sep 6;113(36):E5257-8. doi: 10.1073/pnas.1610228113. Epub 2016 Aug 19. No abstract available.

47.

Regulation of osteosarcoma cell lung metastasis by the c-Fos/AP-1 target FGFR1.

Weekes D, Kashima TG, Zandueta C, Perurena N, Thomas DP, Sunters A, Vuillier C, Bozec A, El-Emir E, Miletich I, Patiño-Garcia A, Lecanda F, Grigoriadis AE.

Oncogene. 2016 Jun 2;35(22):2948. doi: 10.1038/onc.2015.420. No abstract available.

PMID:
27251742
48.

Targeting folate receptor alpha for cancer treatment.

Cheung A, Bax HJ, Josephs DH, Ilieva KM, Pellizzari G, Opzoomer J, Bloomfield J, Fittall M, Grigoriadis A, Figini M, Canevari S, Spicer JF, Tutt AN, Karagiannis SN.

Oncotarget. 2016 Aug 9;7(32):52553-52574. doi: 10.18632/oncotarget.9651. Review.

49.

Matrix-Gla protein promotes osteosarcoma lung metastasis and associates with poor prognosis.

Zandueta C, Ormazábal C, Perurena N, Martínez-Canarias S, Zalacaín M, Julián MS, Grigoriadis AE, Valencia K, Campos-Laborie FJ, Rivas Jde L, Vicent S, Patiño-García A, Lecanda F.

J Pathol. 2016 Aug;239(4):438-49. doi: 10.1002/path.4740. Epub 2016 Jun 29.

PMID:
27172275
50.

Mutation Processes in 293-Based Clones Overexpressing the DNA Cytosine Deaminase APOBEC3B.

Akre MK, Starrett GJ, Quist JS, Temiz NA, Carpenter MA, Tutt AN, Grigoriadis A, Harris RS.

PLoS One. 2016 May 10;11(5):e0155391. doi: 10.1371/journal.pone.0155391. eCollection 2016.

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