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Items: 1 to 50 of 256

1.

Prognostic Role of Circulating miRNAs in Early-Stage Non-Small Cell Lung Cancer.

Ulivi P, Petracci E, Marisi G, Baglivo S, Chiari R, Billi M, Canale M, Pasini L, Racanicchi S, Vagheggini A, Delmonte A, Mariotti M, Ludovini V, Bonafè M, Crinò L, Grignani F.

J Clin Med. 2019 Jan 23;8(2). pii: E131. doi: 10.3390/jcm8020131.

2.

Eicosapentaenoic acid induces DNA demethylation in carcinoma cells through a TET1-dependent mechanism.

Ceccarelli V, Valentini V, Ronchetti S, Cannarile L, Billi M, Riccardi C, Ottini L, Talesa VN, Grignani F, Vecchini A.

FASEB J. 2018 May 14:fj201800245R. doi: 10.1096/fj.201800245R. [Epub ahead of print]

PMID:
29757674
3.

PML is required for telomere stability in non-neoplastic human cells.

Marchesini M, Matocci R, Tasselli L, Cambiaghi V, Orleth A, Furia L, Marinelli C, Lombardi S, Sammarelli G, Aversa F, Minucci S, Faretta M, Pelicci PG, Grignani F.

Oncogene. 2016 Apr 7;35(14):1876. doi: 10.1038/onc.2015.312. No abstract available.

PMID:
27052595
4.

Targeting the KRAS variant for treatment of non-small cell lung cancer: potential therapeutic applications.

Ricciuti B, Leonardi GC, Metro G, Grignani F, Paglialunga L, Bellezza G, Baglivo S, Mencaroni C, Baldi A, Zicari D, Crinò L.

Expert Rev Respir Med. 2016;10(1):53-68. doi: 10.1586/17476348.2016.1115349. Epub 2015 Nov 17. Review.

PMID:
26714748
5.

miRNAs and resistance to EGFR-TKIs in EGFR-mutant non-small cell lung cancer: beyond 'traditional mechanisms' of resistance.

Ricciuti B, Mecca C, Cenci M, Leonardi GC, Perrone L, Mencaroni C, Crinò L, Grignani F, Baglivo S, Chiari R, Sidoni A, Paglialunga L, Currà MF, Murano E, Minotti V, Metro G.

Ecancermedicalscience. 2015 Sep 2;9:569. doi: 10.3332/ecancer.2015.569. eCollection 2015.

6.

PML is required for telomere stability in non-neoplastic human cells.

Marchesini M, Matocci R, Tasselli L, Cambiaghi V, Orleth A, Furia L, Marinelli C, Lombardi S, Sammarelli G, Aversa F, Minucci S, Faretta M, Pelicci PG, Grignani F.

Oncogene. 2016 Apr 7;35(14):1811-21. doi: 10.1038/onc.2015.246. Epub 2015 Jun 29. Erratum in: Oncogene. 2016 Apr 7;35(14):1876.

7.

RARs and microRNAs.

Nervi C, Grignani F.

Subcell Biochem. 2014;70:151-79. doi: 10.1007/978-94-017-9050-5_8. Review.

PMID:
24962885
8.

Eicosapentaenoic acid activates RAS/ERK/C/EBPβ pathway through H-Ras intron 1 CpG island demethylation in U937 leukemia cells.

Ceccarelli V, Nocentini G, Billi M, Racanicchi S, Riccardi C, Roberti R, Grignani F, Binaglia L, Vecchini A.

PLoS One. 2014 Jan 13;9(1):e85025. doi: 10.1371/journal.pone.0085025. eCollection 2014.

9.

Transcriptional fine-tuning of microRNA-223 levels directs lineage choice of human hematopoietic progenitors.

Vian L, Di Carlo M, Pelosi E, Fazi F, Santoro S, Cerio AM, Boe A, Rotilio V, Billi M, Racanicchi S, Testa U, Grignani F, Nervi C.

Cell Death Differ. 2014 Feb;21(2):290-301. doi: 10.1038/cdd.2013.145. Epub 2013 Oct 18.

10.

Epigenetic role of miRNAs in normal and leukemic hematopoiesis.

Pagano F, De Marinis E, Grignani F, Nervi C.

Epigenomics. 2013;5(5):539-52. doi: 10.2217/epi.13.55.

11.

A pool of peptides extracted from wheat bud chromatin inhibits tumor cell growth by causing defective DNA synthesis.

Mancinelli L, Secca T, De Angelis PM, Mancini F, Marchesini M, Marinelli C, Barberini L, Grignani F.

Cell Div. 2013 Aug 6;8:11. doi: 10.1186/1747-1028-8-11. eCollection 2013.

12.

Transcriptional targeting by microRNA-polycomb complexes: a novel route in cell fate determination.

Zardo G, Ciolfi A, Vian L, Billi M, Racanicchi S, Grignani F, Nervi C.

Cell Cycle. 2012 Oct 1;11(19):3543-9. doi: 10.4161/cc.21468. Epub 2012 Aug 16.

13.

Polycombs and microRNA-223 regulate human granulopoiesis by transcriptional control of target gene expression.

Zardo G, Ciolfi A, Vian L, Starnes LM, Billi M, Racanicchi S, Maresca C, Fazi F, Travaglini L, Noguera N, Mancini M, Nanni M, Cimino G, Lo-Coco F, Grignani F, Nervi C.

Blood. 2012 Apr 26;119(17):4034-46. doi: 10.1182/blood-2011-08-371344. Epub 2012 Feb 10. Erratum in: Blood. 2014 Feb 20;123(8):1279.

PMID:
22327224
14.

Eicosapentaenoic acid demethylates a single CpG that mediates expression of tumor suppressor CCAAT/enhancer-binding protein delta in U937 leukemia cells.

Ceccarelli V, Racanicchi S, Martelli MP, Nocentini G, Fettucciari K, Riccardi C, Marconi P, Di Nardo P, Grignani F, Binaglia L, Vecchini A.

J Biol Chem. 2011 Aug 5;286(31):27092-102. doi: 10.1074/jbc.M111.253609. Epub 2011 Jun 9.

15.

Blocking the APRIL circuit enhances acute myeloid leukemia cell chemosensitivity.

Bonci D, Musumeci M, Coppola V, Addario A, Conticello C, Hahne M, Gulisano M, Grignani F, De Maria R.

Haematologica. 2008 Dec;93(12):1899-902. doi: 10.3324/haematol.13035. Epub 2008 Oct 6.

16.

Epigenetic reprogramming of breast cancer cells by valproic acid occurs regardless of estrogen receptor status.

Travaglini L, Vian L, Billi M, Grignani F, Nervi C.

Int J Biochem Cell Biol. 2009 Jan;41(1):225-34. doi: 10.1016/j.biocel.2008.08.019. Epub 2008 Aug 22.

PMID:
18789398
17.

A three-step pathway comprising PLZF/miR-146a/CXCR4 controls megakaryopoiesis.

Labbaye C, Spinello I, Quaranta MT, Pelosi E, Pasquini L, Petrucci E, Biffoni M, Nuzzolo ER, Billi M, Foà R, Brunetti E, Grignani F, Testa U, Peschle C.

Nat Cell Biol. 2008 Jul;10(7):788-801. doi: 10.1038/ncb1741. Epub 2008 Jun 22.

PMID:
18568019
18.

Oncoproteins, heterochromatin silencing and microRNAs: a new link for leukemogenesis.

Nervi C, Fazi F, Grignani F.

Epigenetics. 2008 Jan-Feb;3(1):1-4. Review.

PMID:
18416028
19.

Epigenetic silencing of the myelopoiesis regulator microRNA-223 by the AML1/ETO oncoprotein.

Fazi F, Racanicchi S, Zardo G, Starnes LM, Mancini M, Travaglini L, Diverio D, Ammatuna E, Cimino G, Lo-Coco F, Grignani F, Nervi C.

Cancer Cell. 2007 Nov;12(5):457-66.

20.

deltaN-p73 is a transcriptional target of the PML/RARalpha oncogene in myeloid differentiation.

Mainardi S, Pelosi A, Palescandolo E, Riccioni R, Fontemaggi G, Diverio D, Testa U, Sacchi A, Grignani F, Lo-Coco F, Levrero M, Blandino G, Rizzo MG.

Cell Death Differ. 2007 Nov;14(11):1968-71. Epub 2007 Aug 10. No abstract available.

21.

MicroRNAs 17-5p-20a-106a control monocytopoiesis through AML1 targeting and M-CSF receptor upregulation.

Fontana L, Pelosi E, Greco P, Racanicchi S, Testa U, Liuzzi F, Croce CM, Brunetti E, Grignani F, Peschle C.

Nat Cell Biol. 2007 Jul;9(7):775-87. Epub 2007 Jun 24.

PMID:
17589498
22.

Heterochromatic gene repression of the retinoic acid pathway in acute myeloid leukemia.

Fazi F, Zardo G, Gelmetti V, Travaglini L, Ciolfi A, Di Croce L, Rosa A, Bozzoni I, Grignani F, Lo-Coco F, Pelicci PG, Nervi C.

Blood. 2007 May 15;109(10):4432-40. Epub 2007 Jan 23.

PMID:
17244680
23.

Btg2 enhances retinoic acid-induced differentiation by modulating histone H4 methylation and acetylation.

Passeri D, Marcucci A, Rizzo G, Billi M, Panigada M, Leonardi L, Tirone F, Grignani F.

Mol Cell Biol. 2006 Jul;26(13):5023-32.

24.

Targeting fusion protein/corepressor contact restores differentiation response in leukemia cells.

Racanicchi S, Maccherani C, Liberatore C, Billi M, Gelmetti V, Panigada M, Rizzo G, Nervi C, Grignani F.

EMBO J. 2005 Mar 23;24(6):1232-42. Epub 2005 Feb 24. Erratum in: EMBO J. 2005 May 18;24(10):1899.

25.

Long-term survival after videothoracoscopic lobectomy for stage I lung cancer.

Roviaro G, Varoli F, Vergani C, Nucca O, Maciocco M, Grignani F.

Chest. 2004 Sep;126(3):725-32.

PMID:
15364748
26.

Expression of SMRTbeta promotes ligand-induced activation of mutated and wild-type retinoid receptors.

Côté S, McNamara S, Brambilla D, Bianchini A, Rizzo G, del Rincón SV, Grignani F, Nervi C, Miller WH Jr.

Blood. 2004 Dec 15;104(13):4226-35. Epub 2004 Aug 19.

PMID:
15319284
27.

Non-small cell lung cancer with chest wall invasion: evolution of surgical treatment and prognosis in the last 3 decades.

Roviaro G, Varoli F, Grignani F, Vergani C, Pagano C, Maciocco M, Romanelli A.

Chest. 2003 May;123(5):1341-7.

PMID:
12740245
28.

PML/RAR alpha fusion protein expression in normal human hematopoietic progenitors dictates myeloid commitment and the promyelocytic phenotype.

Grignani F, Valtieri M, Gabbianelli M, Gelmetti V, Botta R, Luchetti L, Masella B, Morsilli O, Pelosi E, Samoggia P, Pelicci PG, Peschle C.

Blood. 2000 Aug 15;96(4):1531-7.

PMID:
10942402
29.

Gene regulation in normal and leukaemic progenitor/stem cells.

De Maria R, Grignani F, Testa U, Valtieri M, Ziegler BL, Peschle C.

Haematologica. 1999 Jun;84 Suppl EHA-4:8-10. Review. No abstract available.

PMID:
10907455
30.

Formation of PML/RAR alpha high molecular weight nuclear complexes through the PML coiled-coil region is essential for the PML/RAR alpha-mediated retinoic acid response.

Grignani F, Gelmetti V, Fanelli M, Rogaia D, De Matteis S, Ferrara FF, Bonci D, Grignani F, Nervi C, Pelicci PG.

Oncogene. 1999 Nov 4;18(46):6313-21.

31.

Very large amounts of peripheral blood progenitor cells eliminate severe thrombocytopenia after high-dose melphalan in advanced breast cancer patients.

Benedetti G, Patoia L, Giglietti A, Alessio M, Pelicci P, Grignani F.

Bone Marrow Transplant. 1999 Nov;24(9):971-9.

32.

Negative regulation of erythropoiesis by caspase-mediated cleavage of GATA-1.

De Maria R, Zeuner A, Eramo A, Domenichelli C, Bonci D, Grignani F, Srinivasula SM, Alnemri ES, Testa U, Peschle C.

Nature. 1999 Sep 30;401(6752):489-93.

PMID:
10519553
33.

Expression of caveolin-1 is required for the transport of caveolin-2 to the plasma membrane. Retention of caveolin-2 at the level of the golgi complex.

Parolini I, Sargiacomo M, Galbiati F, Rizzo G, Grignani F, Engelman JA, Okamoto T, Ikezu T, Scherer PE, Mora R, Rodriguez-Boulan E, Peschle C, Lisanti MP.

J Biol Chem. 1999 Sep 3;274(36):25718-25.

34.

Natural killer cell-mediated lysis of autologous cells modified by gene therapy.

Liberatore C, Capanni M, Albi N, Volpi I, Urbani E, Ruggeri L, Mencarelli A, Grignani F, Velardi A.

J Exp Med. 1999 Jun 21;189(12):1855-62.

35.

Expression and role of PML gene in normal adult hematopoiesis: functional interaction between PML and Rb proteins in erythropoiesis.

Labbaye C, Valtieri M, Grignani F, Puglisi R, Luchetti L, Masella B, Alcalay M, Testa U, Peschle C.

Oncogene. 1999 Jun 10;18(23):3529-40.

36.

Atypical response to all-trans retinoic acid in a der(5)t(5;17) acute promyelocytic leukemia.

Mozziconacci MJ, Liberatore C, Grignani F, Sainty D, Pelicci PG, Birg F, Lafage-Pochitaloff M.

Leukemia. 1999 Jun;13(6):862-8.

37.

Role of T-helper type 2 cytokines in down-modulation of fas mRNA and receptor on the surface of activated CD4(+) T cells: molecular basis for the persistence of the allergic immune response.

Spinozzi F, Agea E, Fizzotti M, Bassotti G, Russano A, Droetto S, Bistoni O, Grignani F, Bertotto A.

FASEB J. 1998 Dec;12(15):1747-53.

PMID:
9837865
38.

Caspases mediate retinoic acid-induced degradation of the acute promyelocytic leukemia PML/RARalpha fusion protein.

Nervi C, Ferrara FF, Fanelli M, Rippo MR, Tomassini B, Ferrucci PF, Ruthardt M, Gelmetti V, Gambacorti-Passerini C, Diverio D, Grignani F, Pelicci PG, Testi R.

Blood. 1998 Oct 1;92(7):2244-51.

PMID:
9746761
39.

Cooperation between the RING + B1-B2 and coiled-coil domains of PML is necessary for its effects on cell survival.

Fagioli M, Alcalay M, Tomassoni L, Ferrucci PF, Mencarelli A, Riganelli D, Grignani F, Pozzan T, Nicoletti I, Grignani F, Pelicci PG.

Oncogene. 1998 Jun 4;16(22):2905-13.

40.

In vitro response to all-trans retinoic acid of acute promyelocytic leukemias with nonreciprocal PML/RARA or RARA/PML fusion genes.

Mozziconacci MJ, Liberatore C, Brunel V, Grignani F, Arnoulet C, Ferrucci PF, Fernandez F, Sainty D, Pelicci PG, Birg F, Lafage-Pochitaloff M.

Genes Chromosomes Cancer. 1998 Jul;22(3):241-50.

PMID:
9624536
41.

The PML/RARalpha fusion protein inhibits tumor necrosis factor-alpha-induced apoptosis in U937 cells and acute promyelocytic leukemia blasts.

Testa U, Grignani F, Samoggia P, Zanetti C, Riccioni R, Lo Coco F, Diverio D, Felli N, Passerini CG, Grell M, Pelicci PG, Peschle C.

J Clin Invest. 1998 May 15;101(10):2278-89.

42.

The acute promyelocytic leukaemia specific PML and PLZF proteins localize to adjacent and functionally distinct nuclear bodies.

Ruthardt M, Orleth A, Tomassoni L, Puccetti E, Riganelli D, Alcalay M, Mannucci R, Nicoletti I, Grignani F, Fagioli M, Pelicci PG.

Oncogene. 1998 Apr 16;16(15):1945-53.

43.

Terminal megakaryocytic differentiation of TF-1 cells is induced by phorbol esters and thrombopoietin and is blocked by expression of PML/RARalpha fusion protein.

Testa U, Grignani F, Hassan HJ, Rogaia D, Masciulli R, Gelmetti V, Guerriero R, Macioce G, Liberatore C, Barberi T, Mariani G, Pelicci PG, Peschle C.

Leukemia. 1998 Apr;12(4):563-70.

44.

Endoscopic treatment of bronchopleural fistulas.

Varoli F, Roviaro G, Grignani F, Vergani C, Maciocco M, Rebuffat C.

Ann Thorac Surg. 1998 Mar;65(3):807-9.

PMID:
9527218
45.

Defective expression of Fas messenger RNA and Fas receptor on pulmonary T cells from patients with asthma.

Spinozzi F, Fizzotti M, Agea E, Piattoni S, Droetto S, Russano A, Forenza N, Bassotti G, Grignani F, Bertotto A.

Ann Intern Med. 1998 Mar 1;128(5):363-9.

PMID:
9490596
46.

Fusion proteins of the retinoic acid receptor-alpha recruit histone deacetylase in promyelocytic leukaemia.

Grignani F, De Matteis S, Nervi C, Tomassoni L, Gelmetti V, Cioce M, Fanelli M, Ruthardt M, Ferrara FF, Zamir I, Seiser C, Grignani F, Lazar MA, Minucci S, Pelicci PG.

Nature. 1998 Feb 19;391(6669):815-8.

PMID:
9486655
47.

The promyelocytic leukemia gene product (PML) forms stable complexes with the retinoblastoma protein.

Alcalay M, Tomassoni L, Colombo E, Stoldt S, Grignani F, Fagioli M, Szekely L, Helin K, Pelicci PG.

Mol Cell Biol. 1998 Feb;18(2):1084-93.

48.

High-efficiency gene transfer and selection of human hematopoietic progenitor cells with a hybrid EBV/retroviral vector expressing the green fluorescence protein.

Grignani F, Kinsella T, Mencarelli A, Valtieri M, Riganelli D, Grignani F, Lanfrancone L, Peschle C, Nolan GP, Pelicci PG.

Cancer Res. 1998 Jan 1;58(1):14-9.

49.

Cell death induction by the acute promyelocytic leukemia-specific PML/RARalpha fusion protein.

Ferrucci PF, Grignani F, Pearson M, Fagioli M, Nicoletti I, Pelicci PG.

Proc Natl Acad Sci U S A. 1997 Sep 30;94(20):10901-6.

50.

Characterization of the retinoid binding properties of the major fusion products present in acute promyelocytic leukemia cells.

Benedetti L, Levin AA, Scicchitano BM, Grignani F, Allenby G, Diverio D, Lo Coco F, Avvisati G, Ruthardt M, Adamo S, Pelicci PG, Nervi C.

Blood. 1997 Aug 1;90(3):1175-85.

PMID:
9242550

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